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Product Summary

Claims Overview

® ® ® ®
Synovea ® HR
Asyntra D-Stress VitaSynol C Synoxyl AZ Synoxyl HSS
& Asyntra ® SL
Microbiome Friendly 24/7
A Breakthrough Photostabilizer The Gold Standards In Skin Lightening
Destress Your Skin Stable and Bioavailable Vit C Prevention & Repair of Skin
with In-vivo SPF Boosting & Even Toning
Damage

Hexylresorcinol;
Isosorbide Dicaprylate, Bakuchiol, Trimethoxybenzylidene
Tetrahexyldecyl Ascorbate Acetyl Zingerone Caprylic/Capric Triglycerides, Ethyl
Ethyl Linoleate Pentanedione Linoleate, Hexylresorcinol

Synactin ® AC Sytenol ® A Synastol ® TC Hydra Synol ® DOI Synovea ® EL


5-in-1 Solutions for Mitigating Acne- The True alternative The Holistic Solution to Pollution A Smart Lipophilic Skin Hydrator A Smart Synergist with Multiple
affected Skin to Retinol & Blue Light Damage & Barrier Builder Skin Benefits

Caprylic/Capric Triglycerides, Ethyl Bakuchiol Terminalia Chebula Fruit Extract Isosorbide Dicaprylate Ethyl Linoleate
Linoleate, Hexylresorcinol

More info on www.sytheonltd.com


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®
Asyntra D-Stress
Destress Your Skin

In-vitro data Clinical Use


INCI Applications Origin
and biological properties studies level

Isosorbide • Enhances Anandamide (the bliss molecule) by • Enhances innate antioxidant system to fight 2 to 4% • Stress relief products Green
Dicaprylate, reducing FAAH and FABP-5 Enzymes against inflammation • Sensitive skin chemistry,
Bakuchiol, • Strengthens skin barrier by boosting ceramides • Maintains hydration through strengthening skin Plant,
Ethyl Linoleate • Even toner Extraction
• Reduces stress by repressing cortisol (stress barrier
marker) • Calms skin redness in rosacea-prone skin
• Performance enhancer for CBD & Hemp Oil subjects

Sytheon Ltd.
10 Waterview boulevard, Parsippany, NJ 07054
Email: info@sytheonltd.com
Tel: +1 973.988.1075

Sytheon France
88 Avenue du Général Leclerc, 92100 Boulogne-Billancourt
Email : sytheon@sytheonltd.com
Tel: +33 (0)1.4110.8182
More info on www.sytheonltd.com
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®
VitaSynol C
Stable and Bioavailable Vitamin C

In-vitro data Clinical Use


INCI Applications Origin
and biological properties studies level

Tetrahexyldecyl • Improved stability against heat and oxidation • Corrects & prevents intrinsic & extrinsic aging 2 to 30% • Corrects & prevents Organic
Ascorbate compared to Vitamin C • Reduces UV induced pigmentation, even toning intrinsic & extrinsic synthesis
• Easy to formulate due to lipophilicity aging
• Reduces melanin synthesis by tyrosinase • Reduces UV induced
inhibition pigmentation, even
toning
• Reduces UV-induced cell damage
• Increases Collagen synthesis and reduces its
degradation
• Improves stability & performances when
combined with Synoxyl® AZ

Sytheon Ltd.
10 Waterview boulevard, Parsippany, NJ 07054
Email: info@sytheonltd.com
Tel: +1 973.988.1075

Sytheon France
88 Avenue du Général Leclerc, 92100 Boulogne-Billancourt
Email : sytheon@sytheonltd.com
Tel: +33 (0)1.4110.8182
More info on www.sytheonltd.com
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®
Synoxyl AZ
Microbiome Friendly 24/7 Prevention & Repair of Skin Damage

In-vitro data Clinical Use


INCI Applications Origin
and biological properties studies level

Acetyl Zingerone • All-in-one – Antioxidant, Quencher & Selective • Significant reduction (>25%) in wrinkles, uneven 0.5 to 1% • Sun Preparation: Organic
Chelator – First in the Industry pigmentation & skin redness in 4 weeks Photoaging prevention synthesis
• Reduces immediate and delayed skin damages • Improved skin’s defenses by protecting UV- • After-Sun: Photoaging
( CPDs) – First in the Industry induced damages repair
• Photochemically stable antioxidant in contrast • Complementary
to conventional antioxidants Biological Protection to
• Maintains ECM integrity by strongly SPF products
upregulating all six matrisome genes/proteins • Anti-pollution: Skin
• Reverses sign of cellular senescence Detox

Sytheon Ltd.
10 Waterview boulevard, Parsippany, NJ 07054
Email: info@sytheonltd.com
Tel: +1 973.988.1075

Sytheon France
88 Avenue du Général Leclerc, 92100 Boulogne-Billancourt
Email : sytheon@sytheonltd.com
Tel: +33 (0)1.4110.8182
More info on www.sytheonltd.com
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®
Synoxyl HSS
A Breakthrough Photostabilizer with In-vivo SPF Boosting

In-vitro data Clinical Use


INCI Applications Origin
and biological properties studies level

Trimethoxybenzy- • Highly effective photostabilizer compared to • Cost-effective high-performance sunscreen 0.5 to 2.5% • High SPF ecofriendly Organic
lidene commercial stabilizers products sunscreens based on synthesis
Pentanedione • Reduces formation of radicals • In-vivo SPF boosting by ≥50% in organic organic or inorganic UV
& inorganic sunscreens while alone no Filters
• Biodegradable – Ecofriendly sunscreen
products contribution to SPF • Color cosmetics
(Lipsticks)
• Toiletries using
photosensitive
fragrances and/or dyes

Sytheon Ltd.
10 Waterview boulevard, Parsippany, NJ 07054
Email: info@sytheonltd.com
Tel: +1 973.988.1075

Sytheon France
88 Avenue du Général Leclerc, 92100 Boulogne-Billancourt
Email : sytheon@sytheonltd.com
Tel: +33 (0)1.4110.8182
More info on www.sytheonltd.com
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® ®
Synovea HR & Asyntra SL
The Gold Standards In Skin Lightening & Even Toning

In-vitro data Clinical Use


INCI Applications Origin
and biological properties studies level

Hexylresorcinol; • Multi-targeted (8 sites) inhibition of melanin • Skin lightening & even toning 0.5 to 1% • Skin lightening and even Organic
Caprylic/Capric synthesis • Works for normal & hyperpigmented skin of all toner synthesis
Triglycerides, Ethyl • In direct antioxidant – stimulates glutathione phototypes 2 to 4% • Hyperpigmentation or
Linoleate, Hexylre- • Strong reduction in proinflammatory biomarker • Proven to be 2 to 4-times more effective than dark spots correction
sorcinol NF-kB Hydroquinone • Asyntra® SL is a
• Significant improvement in skin complexion synergistic liquid blend
of Hexylresorcinol &
Ethyl Linoleate

Sytheon Ltd.
10 Waterview boulevard, Parsippany, NJ 07054
Email: info@sytheonltd.com
Tel: +1 973.988.1075

Sytheon France
88 Avenue du Général Leclerc, 92100 Boulogne-Billancourt
Email : sytheon@sytheonltd.com
Tel: +33 (0)1.4110.8182
More info on www.sytheonltd.com
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®
Synactin AC
5-in-1 Solutions for Mitigating Acne-affected
Skin

In-vitro data Clinical Use


INCI Applications Origin
and biological properties studies level

Caprylic/Capric • Regulates follicular keratinization & barrier • Mitigates all major targets of acne-affected 2 to 4% • Anti-acne Organic
Triglycerides, Ethyl function skin • Post-inflammatory synthesis
Linoleate, Hexylre- • Decreases sebaceous gland activity • Improves skin texture & complexion pigmentation
sorcinol treatments for
• Decreases follicular bacterial population • Significant reduction in skin erythema
phototypes IV, V & VI
• Produces anti-inflammatory effect
• Reduces post-inflammatory hyperpigmentation

Sytheon Ltd.
10 Waterview boulevard, Parsippany, NJ 07054
Email: info@sytheonltd.com
Tel: +1 973.988.1075

Sytheon France
88 Avenue du Général Leclerc, 92100 Boulogne-Billancourt
Email : sytheon@sytheonltd.com
Tel: +33 (0)1.4110.8182
More info on www.sytheonltd.com
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®
Sytenol A
The True alternative to Retinol

In-vitro data Clinical Use


INCI Applications Origin
and biological properties studies level

Bakuchiol • Retinol-like activity (DNA microarray & PCR • Double-blind, randomized comparative clinical 0.5 to 1% • Antiaging - day & night Plant,
array) study with Retinol – significant reduction in • Antiacne >99%
• Boosts Collagen I, III & IV wrinkle surface area & hyperpigmentation; pure well-
much better skin tolerance than Retinol • Sun preparation: defined
• Inhibits MMPs Preventative protection compound
• Anti-acne study- significant reduction in acne
• Broad-action antioxidant lesion & improvement in skin complexion
• Protects mitochondrial genome
• Increases mitochondrial biogenesis

NATRUE
APPROVED

Sytheon Ltd.
10 Waterview boulevard, Parsippany, NJ 07054
Email: info@sytheonltd.com
Tel: +1 973.988.1075

Sytheon France
88 Avenue du Général Leclerc, 92100 Boulogne-Billancourt
Email : sytheon@sytheonltd.com
Tel: +33 (0)1.4110.8182
More info on www.sytheonltd.com
>> Home page

®
Synastol TC
The Holistic Solution to Pollution
& Blue Light Damage

In-vitro data Clinical Use


INCI Applications Origin
and biological properties studies level

Terminalia Chebula • Significantly reduces oxidative stress induced • Reduces wrinkle depth & skin roughness 0.5 to 1% • Anti-pollution: skin detox Plant,
Fruit Extract by urban dust & blue light • Significant reduction in under-eye dark circle & blue light protection direct
• Significant reduction in pro-inflammatory • Green cosmetic skin extraction
• Provides even skin tone
biomarkers – IL-6 & IL-8 care: super fruit with
• Reduces & repairs barrier dysfunction ayurvedic claims
• Cascading & broad-action super fruit • Anti-aging
antioxidant
• Multitargeted anti-aging product –
Antiglycation & Glycation reversal

Sytheon Ltd.
10 Waterview boulevard, Parsippany, NJ 07054
Email: info@sytheonltd.com
Tel: +1 973.988.1075

Sytheon France
88 Avenue du Général Leclerc, 92100 Boulogne-Billancourt
Email : sytheon@sytheonltd.com
Tel: +33 (0)1.4110.8182
More info on www.sytheonltd.com
>> Home page

®
Hydra Synol DOI
A Smart Lipophilic Skin Hydrator
& Barrier Builder

In-vitro data Clinical Use


INCI Applications Origin
and biological properties studies level

Isosorbide • Multitargeted skin hydrator & barrier builder • Smart skin hydrator – helps move moisture 2 to 4% • Long lasting skin Plant,
Dicaprylate (DNA microarray & PCR array) where it is needed hydrator Green
• Stimulates AQP-3 gene (& protein), CD44, tight • Very effective in providing long-lasting • Barrier building cremes/ chemistry
junctions, desmosome, Epidermal genes/ (>48 hrs.) & controlled hydration lotions
proteins • Improves & extends tanning effect in glow • Hair gloss products
• Upregulation of E-Cadherin provides skin products • Self-tanning glow
homeostasis products
• Baby care & color
cosmetics

Sytheon Ltd.
10 Waterview boulevard, Parsippany, NJ 07054
Email: info@sytheonltd.com
Tel: +1 973.988.1075

Sytheon France
88 Avenue du Général Leclerc, 92100 Boulogne-Billancourt
Email : sytheon@sytheonltd.com
Tel: +33 (0)1.4110.8182
More info on www.sytheonltd.com
>> Home page

®
Synovea EL
A Smart Synergist with Multiple Skin Benefits

In-vitro data Clinical Use


INCI Applications Origin
and biological properties studies level

Ethyl Linoleate • Stimulates genes associated with fatty acid • Reduces multiple signs of acne when 2 to 5% • Skin hydration Plant,
transport, long-chain fatty acid metabolism, combined with Triethyl Citrate • Anti-acne products Green
and lipid localization • Enhances skin lightening effect when chemistry
• Hyperpigmentation
• Stimulates genes associated with the negative combined with Synovea® HR treatments
regulation of adaptive immunity and leukocyte • Maintains stratum corneum acid mantle
proliferation
• Dose-dependent inhibition of proinflammatory
biomarker NF-kB

Sytheon Ltd.
10 Waterview boulevard, Parsippany, NJ 07054
Email: info@sytheonltd.com
Tel: +1 973.988.1075

Sytheon France
88 Avenue du Général Leclerc, 92100 Boulogne-Billancourt
Email : sytheon@sytheonltd.com
Tel: +33 (0)1.4110.8182
More info on www.sytheonltd.com
>> Home page

Asyntra ® D-Stress VitaSynol ® C Synoxyl ® AZ Synoxyl ® HSS Synovea ® HR Synactin ® AC Sytenol ® A Synastol ® TC Hydra Synovea ® EL

& Asyntra ® SL Synol ® DOI

Anti-aging

Hyperpigmentation-control

Skin Hydration

Skin Redness

Anti-acne

Skin Lightening

Anti-inflammation

Under-Eye Dark Circles

Skin Tone

Skin Barrier Repair

Skin Protection

Anti-wrinkle

Skin Elasticity

Photostabilizer

Antioxidant*

Anti-pollution/Blue Light

SPF Booster

Solubilizer

Oil Soluble

Water Soluble

Color intensity determines the degree of effectiveness of the active ingredient


represents indirect antioxidant activity

More info on www.sytheonltd.com

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