MISCELLANEOUS DRUGS

1.Man take overdose from drug then take the antidote but still no effect, why?

antidote dose was small

2. Biological substance can be stored at … C ? 2 – 80C

3. What pharmacist should do when wrong medication prescribed from Dr?

Inform prescriber doctor

4.Example of drug - disease interaction?

Pioglitazone & heart failure, Celecoxib & Cardiac toxicity

5. Bioavailability refers to extent and rate at which the active moiety enters?

systemic circulation or "site of action"

6. Anti-dote of iron? Desferoxamine

(Desferoxamine acts by binding free iron in the blood stream and enhancing its
elimination in the urine )

7. Drug acts on non-receptor mechanism? Drug is used to remove excess iron

by binding to free iron? Desferoxamine

8. Decrease or increase dose to the patient by technician is?

Omission error Or improper dose error

9. Types of error in Pharmacy? dispensing error

10. Nurse gives patient dose 2 hours later, what is the type of error?

wrong time error , administration error

11. Example of error of deteriorating drug? giving expired drug, storing

drug out Refrigerator

12. Most occurring error in prescription? wrong drug order

13. Most error that may occur when patient is transferred from one unit of facility
to another? missing drug he was taking

14.Which committee rules out a drug from the hospital? Therapeutic

evaluation committee

15. Non formulary drug order reviewed by? Management of the drug? Removing a
drug from formulary? Formula of drug can be adjusted by?

Pharmacy & therapeutic committee

16. BUN , Creatinine , Potassium , Sodium is high so patient should stop?

Gemfibrozil or Metformin

17. Patient with pneumonia went to hospital to get vaccine, which should give?

Pregnant women suffer from upper respiratory disease took ceftriaxone IV, Which
vaccines hospital should give her?

Patient suffers from lung obstruction, which vaccine should he take?

both Pneumonia and Influenza

18.What will happen if we break down sustained release drug instead of using it as
tablet? Toxicity

19. What is the toxic when breakup sustained release drug? multi-dose
toxicity

20. Who is the reasonable for determining the best dosage form?
Pharmacist/Clinical pharmacist

21. In large amount of parental medication, we use? Sterile water for

Injection

22. Teething gel for children contain? Anti-septic

23. Drug must keep in dark box, used for pain of toothache, dangerous effect to
infant as seizure and toxicity? Clove oil
24. Man with BMI 85% of his age, so he is? Very obese

25. Child with BMI 85% of his age, so he is? Obese

26. Child with BMI 85% of his age has muscle and skin thickness, so he need test?
Body fat

27. Five years old child with BMI 80% of his age, skin thickness and arm muscles
are normal,so he is? Normal range

28. Taking Mycophenolate "Cellcept" she want to be pregnant?

stop Mycophenolate before 6 weeks of trying to be pregnant

29. When woman start folic acid? before pregnancy with one month and 1st
trimester

30. Pregnant women must take which vaccine? influenza type 2

31. Pregnant have hepatitis B, TTT ?

Hepatitis B vaccine with immunoglobulin hepatitis HBIG

32. Prescription is valid to dispense within? 72 hours

33. Uncontrolled drug maximum prescription time? 90

34. Gasoline fumes induce toxicity of? Lead

35. Anti-dote of lead is? Penicillamine or edetate disodium

calcium (CaNa2EDTA)

36. TDM ? individualize pharmacokinetic parameters

37. Which drug contra-indicated in breastfeeding and pregnancy?
Lithium ( category D )

38. Methotrexate , atorvastatin , simvastatin , warfarin , Finasteride can't be used

in pregnancy? Category X

39. Drug is toxic for neonate in breastfeeding? Metronidazole(1),

Voriconazole(2)

40. What is stopped in lactation? anti-cholinergic as Atropine &

ipratropium "Atrovent"

41. Drugs contraindicated during lactation?

Anticancer , Aspirin , Iodine , Androgen , Bromocriptine , tetracycline

42. What is the most common dispensed OTC in Pharmacy? Oral anti-
septic

43. OTC multi-vitamin analogue? Vitamin D

44. Most common dispensed in OTC ? multi-vitamins or analgesic as

Paracetamol or ibuprofen

45. Non aqueous preparation? Essence colloid and Elixir

46. Albumin & dextran & starch are? colloid solution

47. How many ml syrup you prepare in pharmacy? 60

48. Side effects and adverse drug reaction in geriatrics due to? Major cause of
drug interaction in elderly people due to? Polypharmacy

49. Increase osteoporosis in geriatric will increase? bone fracture

50. Process requires CYP450 ? oxidation

51. Which is Not true about adsorption?

chemical property and irreversible, But true is? Physical property and
reversible
52. Mechanical error during filling the prescription? Dispense the wrong
drug

53. Sign of shock? Hypoperfusion( reduced amount of blood flow)

54. Who is responsible for release of investigational drugs from manufacturer to

Pharmacy?

Chief pharmacist

55. Who sign the form send to FDA to investigate in drug? Chief
pharmacist

56. Task of pharmacists in medical center and hospital? control formulary

of drugs

57. Man came to emergency after burns, toxicity is due to?

Cyanide N.B ; Cyanide toxicity is Cardiac toxicity

58. First baby milk?

( colostrum ) ; yellowish liquid especially rich in immune factors secreted by

mammary gland of female mammals a few days before and after birth of their
young.

59. Lactulose used in hepatic encephalopathy patient to?

acidify the colon to inhibit absorption of ammonia

60. What are the benefits of patient orientation formulary system is hospitals?

safe and effective medicines

61. Desired patient benefits in formulary system in hospital ? ensure effective

and quality drug

62. Type of water used in preparation of cold cream? distilled water

63. When does pharmacist send a report about side effects? every month
64. How many times measure drug conc for therapeutic drug monitoring in stable
patient?

once during therapy

65. To be the medical center contain highly efficient data must be available follow

( choose the appreciate medications and the least side effects )

66. What is the best base to prepare drug for dry skin? ointment base

67. Drug will make bioavailability and stomach incompatibility, if you break the
pill into half? enteric coated

68. Trituration ?

reducing particle size , purification process of crude chemicals containing soluble

impurities , dilution of potent drug power with inert diluent powder usually lactose
in definite proportion by weight

67. Particle size affect the following:

a. solubility
b. dissolution or dissolution rate
c. content-content uniformity
d. suspendability or Suspend ability
e. penetrability
f. Dose to dose uniformity
g.Uniformity of tablet
h. All of the above

68. To be medical center contain highly efficient data?

choose the appropriate medications and least side effects

69. When choosing a drug according to? Safety

70. When FDA need more experiments,analysis,researches about drug in phase 4,

it means?

needs more about safety

71.When pharmacopeia put the drug as phase 4 ? safety

72. How many phases applied to drug to be approved by FDA ? 4 phases

73. Acc to FDA, the most dangerous abbreviation that shouldn't be written on
prescription is? PRN

74. Most dangerous abbreviation put in prescription for pt with pain in joint?

OD , QD , QOD , Q1D, QID

75. 1 kg = 2.2 pound

76. Probiotics ? supplement that give beneficial bacteria and yeast, live yeast or
bacteria that are good for health

77. Elderly man with hypothyroidism and hyperlipidemia, what is CHAD score for
atrial fibrillation prior stroke? ( 2 )

78. In case of 75 years old has HTN , DM , hyperlipidemia what score according to
CHADS?

3, but if acc to chads-VASC ( 4 )

CHF score=1, stroke/transient ischemic attack score=2,HTN=1, DM=1

According to CHADS, age score=1

And According to CHADS-VASC, age score=2

79. Why is isotretinoin "anti-acne" " contra-indicated in pregnancy?

( category X and is vit a derivative that cause abortion in high dose )

80. Osmality of plasma is similar to Osmality of? 0.9% solution of NaCl

'saline'
81. Pt with diabetes, ketoacidosis, blood pressure 90/60 , K slight high , HCO3
low>> initiate with? saline 0.9%

82. Patient with Hemodynamic shock HS treated with? Patient with septic shock ,
BP 70/40 , K slight high? Saline

83. Child with 85% of his weight , what is reason? Subcutaneous fat

84. Breastfeeding strategy to avoid effect of drug taken by mom on baby ?

take medicine after breastfeeding

84. Conc ; 9 ppm = 9 mg in 1000 ml or 1 liter

85. Css is dependent ? T half

86. What should pharmacist do to minimize risk and side effects of otc drugs?

tell him about side effects

87. How much the dose difference in critical ill patient than original patient?
twice

88. White woman came to Dr with osteoporosis, he wrote Ca and vit D and what?
Alendronate

89. Alendronate dose?

( 5 – 10 mg/daily ) " 5 mg once daily or 35 mg once weekly in prevention in

postmenopausal woman – 10 mg once daily or 70 mg once weekly " TTT of
osteoporosis

90. Your advice for pt takes Alendronate?

take it 1/2 hr before breakfast with water and stand upright for 1/2 hr

91. GMP ? ( good manufacturing practice ) , establishment of all safety and

efficiency of drug manufacture procedure
92. Two vaccines live and killed , how can be administered ? at the same
time

93. Patient burn hand when cooking? wash with water for 20-30 min

94. What is vitamin needed in treatment by corticosteroids for 2 years for chronic
disease?

Ca and Vitamin D

95. Which vit D for patients with renal failure ? Calcitriol = 1,25-
dihydroxycholecalciferol

96. At what age tuberculosis vaccine BCG should given ? at birth

97. MMR ?

( mixture of live attenuated viruses ) The vaccines given to immunize against

measles, mumps and rubella

98. MMR vaccine is given at what age? first dose 12 months , second dose 4
years

99. Child is taking high dose of amoxicillin for otitis media, came to hospital for
pneumonia and influenza vaccine ? proceed to give the vaccine

100. Route of administration of Enoxaparin and Morphine?

( Enoxaparin ; SC ) ( Morphine ; IV or oral – IM – rectal )

101. What should you do if Dr prescribe amoxicillin but you have not the brand?
give the generic

102. Dose of Ferrous sulfate ? 600 mg/ day or 300 mg BID

103. Pharmacy regulation and guidelines is coming from?

sFDA or GPhC general pharmaceutical council

104. In which muscle we give vaccine for infants?

the vastus lateralis muscle in the anterolateral thigh

105. Validity of pharmacy permit? 5 years

106. Category B in pregnancy?

( animal reproduction studies have failed to demonstrate risk to the fetus and there
are no adequate and well controlled studies in pregnant woman - May me
acceptable )

Category A ? generally acceptable

Category C ? use with caution

Category D ? use in life threatening

107. Diphtheria ? is an infection caused by the bacterium

Corynebacterium diphtheria

108. Vit C is used for? Preservaive

109. Daily recommended dose of vit C in male ; 90 mg/day (in

female ; 75 mg/day )

110. Role of scientific office in pharmaceutical company ?

provide scientific , technical and marketing information on pharmaceutical

preparations throughout the Kingdom

111. Drug dispensed to patient and nurse found that there was another dose at
patient room? Nurse received extra vial in the bag?
return the dose to pharmacy

112. Baby with immunodeficiency syndrome SCIB took immunoglobulin which

vaccine is contra-indicated? RV rotavirus
113. The best drug delivery in infant? Neutralizer

114. Masking acidic taste of syrup use which flavor? strong base anion
exchange resins

115. Organo-phosphorus toxicity removed by? Pralidoxime and Atropine,

Pralidoxime , Atropine

116. Pt is in omeprazole and it is expired , what is your advice? buy a new one

117. Drug-Disease interaction ?

Furosemide and Osteoporosis

( Furosemide is loop diuretic cause Hypocalcemia and induce osteoporosis NOT

osteoarthritis )

118. Compassionate drug use? use of new un-approved drug

119. Off label ?

medication is used in a manner not specified in FDA approved packaging level

-----Unapproved

120. Pregnant woman should watch out for? vitamin A

(daily intake of vitamin A for adult female is 700 mcg , for adult male is 900
mcg , for breastfeeding is 1200-1300)

121. Sevelamer "Renagel" ?

decrease serum uric acid and phosphorus concentration in chronic kidney disease,
treat hyperphosphatemia

122. Dosage form preferred for children? Oral

123. Biosimilar ?
is biological medical product that is identical copy of original product that is
manufactured by different company, are officially approved versions of original
products and can be manufactured when original products expire.

OR

Biosimilar is a biologic medical , highly similar to another already approved

biological medicine

OR

similar to approved biological product

124. Receptor response in milliseconds and other in seconds?

ligand gated receptors and G – protein receptors

125. Example of isotonic solution ? Ringer solution

126. Example of high alert solution ? dextrose 20%

127. Smoker man drink coffee , take steroid , married to 2 wifes , how many
factors affect ulcer? 3

128. Woman wants the prescription of her drug because her case is like his case as
she said , what will you do ? give her the telephone of prescriber doctor

129. What is the time interval between 2 drugs if half life is 4 hours? 8 hours

130. What are the 5 rights of drug administration? Right patient , drug , dose ,
route , time

131. Base is used in suppository? Cocoa butter

132. More important mentalic multivitamin? which is found in vit B12 ?

Cobalt

133. Tablet must be uniform to ensure? Bioavailability

134. Infant with croup , what is the virus that cause this? Para influenza

135. Which is fast absorption SC or rectal or oral or topical ? SC

136. Side effects of calcium carbonate? constipation

137. One drop has volume of…? variable depending on the liquid and dropper

138. Pharmacovigilance (PV or PhV)? Postapproval standing scientific and data

gathering activities related to the detection , assessment , understanding , prevent
side effects S.E

139. Child swallowed 100 capsules of iron , each cap contains 18mg? gastric
lavage

140. MOA of Benzoyl peroxide gel in Acne ? keratolytic ( N.B ; Benzyl

benzoic acid is used in Acne)

141. Which increase absorption of iron? Vitamin C = ascorbic acid ,

meat and fish

142. MOA of Beta carotene ? is precursor of Vitamin A ( NB ; vit A

= retinol )

143. Who is the patient with multiple prescription Note take OTC? geriatric

144. What is the precaution for child with Neisseria?

isolate to prevent transmission through close respiratory or mucus membrane

contact

145. Girl came to pharmacy with her brother drugs needing same drugs? send
her to doctor

146. Live vaccines?

influenza , measles , mumps , rotavirus , tuberculosis BCG , rubella , yellow

fever , varicella, polio sabin

147. Pregnancy vaccines?

routine : inactivated influenza IIV - Tdap TT/Td >>>> Safe

Not contra-indicated : Hepatitis A and B - Pneumococcal - Meningococcal -

yellow fever - inactivated poliovirus
Contra-indicated : MMR - Live attenuated influenza LAIV - Varicella

148.Test for renal function?

Cr Cl, BUN, urea, Serum Creatine. All is correct but the best is Serum Creatine

149. Most important for constipation patient? daily take water

150. PO ? drug taken by mouth

151. Varicella zoster virus (VZV)? Cause Chickenpox

152. Patient identification by? name and medical record number

153. Cyclosporine is used as? immunosuppressant after organ transplantation

154. Most drug used in immune suppression? ( Cortisone )

first ; anti-inflammatory drugs of cortisosteroid such as Prednisone

Second ; cytotoxic drugs such as Azathioprine and Cyclophosphamide

third ; fungal and bacterial derivatives such as Cyclosporine

155. Nurse wants dose in syringe, how pharmacist dispense the dose?

in vial and she dispense when reach bedside

156. When expire date for drug end in December? 31 December

157. TTT of head lice?

Premethrin – Lindan – Malathion – Ivermectin – Piperonyl butoxid – Itraconazole

– Terbinafin – Benzyl alcohol lotion

158. Most common cause for pediatric dose error than adult? most
medication is liquid

159. Benefit of using the unit-dose-system ? decrease medication error

" Dose error "

160. Normal water is used in? external preparation

161. To say the suspension is good? moderate shaking for reconstitution

(N.B ; in suspension formation , chelating agent is not used )

162. Drug is waiting FDA approval to be formulary of hospital ? drug still

waiting for approval by therapeutic and pharmacy committee? non-formulary

163. Drug is waiting FDA approval to be commercial? un-registered drug

164. Reconsituation antibiotic or refrigerated should be used within? 14 days

165. Pt with renal failure shouldn't take magnesium sulfate, why? it decrease
excretion of magnesium

166. Magnesium is contra-indicated in renal impairment because of…..?

Accumulation

167. If maximum moisturization required use? Lotion

168. Lab test can be done now? iron

169. Lab test have to done today CBC

170. Patient with ulcerative colitis TTT on Cortison and mesalazin , must use ?
Calcium ( as corticosteroid drugs induce osteoporosis )

*If Colitis only without Cortisone , must take ( Vit B12 )

*colitis & cortisone…………..use calcium

*but for prophylaxis must use (Calcium+Vit B12)

171. Folic acid dose in non-pregnant (400mcg/day)

in pregnant (600mcg/day) , in lactating (500mcg/day)

172. P.R.N ? When needed or When required

173. Vaccines should be administered for every pregnancy in 27 and 36 weeks?

Tdap = tetaunes+diaphthria+pertussis

174. The same vaccine of Tdap but for children 0-6 years? Dtap

175. Calcium dose for geriatric? ( 1000 - 1200 mg)

(N.B ; calcium dose for 65 years woman ? 1200 mg )

176.

177. Vit D3 dose for geriatric? (600 iu)

( Vit D for younger than 70 (600 iu) for older than 70 (800 iu))

178. renal clearance + hepatic clearance + lung clearance ? total body

clearance

179. Respiratory acidosis is caused by ? C02 retention

180. P.C = after meals , A.C = before meals , QID=QDS=

4 times daily

181. After drug metabolism, the drug become? Polar

182. Sodium bicarbonate antacid make an out elimination of ? pka = 1.2

weak acid

183. PKa for normal water in room temperature? 14

184. Aspirin pka is 3.2 , will be stable at PH? 2 or 3 or 4 or 6

185. Routine medication for influenza? , which vaccine should be taken

although you don't need it? influenza vaccine

186. Influenza vaccine is contra-indicated in? 0 – 6 months baby

187. Live vaccines are contra-indicated for patients with? CD4 count less than
200

188. . Etidronate is used in ttt of ? Osteoporosis or Paget's disease

189. Emergency members should take what vaccine to avoid nosocomial infection?
Emergemcy staff vaccine?

( Meningitis vaccine )

190. Probiotics ? ( bacteria and yeast eaten to provide patient with health )
191. Which drug can be taken by inhalation? ( Amyl nitrite for angina or
Halothane is a general inhalation anesthetic )

192. Grinding of solid or powder in liquid or ointment? Levigation

193. Change the drug from tablet to final powder? Disintegration

194. Which is used to counteract toxicity of drug after 1 hour of ingestion?

activated charcoal

195. Which of the following is released by bacterial cell wall during phagocytosis?
endotoxin

196. Which of the following is released by bacterial cell wall during infection or
growth? Exotoxin

197. PPM ? part per million Or million part

198. Which drug is used as Antispasmodic? Baclofen

199. Used in Psoriasis ? Coal tar

200. The Latin abbreviation for " Stat "? immediately

201. Which is used to deal with adverse drug effects ? pharmacovigilance

"safety"

202. Study in which we use different studies to make conclusion?

meta analysis(1) or systematic review(2)

203. Toxidrome ? ( over poison induced syndrome ) - ( physical signs

and symptoms due to specific toxicity syndrome )

204. Prescription label should contains? physician name ; in case of

opioid, it contains? patient name

label of drug must contain ; Patient name & Prescription must

contain ; Physician name

205. If a medication error happened , the first person to refer is? Prescriber
206. Unit dose system in hospital? to decrease medication error

207. What is meaning of FDA fast track? ( drugs that shows promising
results for life-threatening disease with No others available can do that )

208. Prevention of cervical precancer and cancer caused by human papilloma virus
16 and 18?

HPV human papilloma virus vaccine

209. What is the vaccine that reduce incidence of infertility ? HPV human
papilloma virus vaccine

210. Unit dose cassettes in hospital has doses of ? Day

211. Who is more prone to influenza symptoms and problems? Pregnant

212. High distribution volume = concentration of drug in tissues is

higher than that in plasma

213. 45 years old man, his volume of distribution is 35L, what is the interpretation?
drug is highly distributed in plasma

Vd = total amount of drug in the body / drug in plasma concentration

214. 1st order elimination ? increase of drug dose >>> increase

elimination rate

215. Another name for soluble solution ? Homogenous

216. Which of the following conditions have non preventable adverse effects ?

( tachycardia with someone forgot his dose of anti-HTN and took 3 pills )

217. Dantrolene ? skeletal muscle relaxant acting as a receptor antagonist to the

ryanodine receptor, and decreasing free intracellular calcium concentration

218. Ergot alkaloids? as Dihydroergotamine and ergotamine , Used

in uterine stimulant

219. Storage of narcotic prescriptions ? ( 36 months )

220. You should keep the prescription of narcotic in pharmacy for? 5 years

221. Drug dependence means? addiction ( N.B ; Benzodiazepines

cause dependence)

222. Dependence ? increase dose of drug associated with withdrawal

symptoms if sudden decrease

223. Tolerance ? increase dose of drug to obtain the same effect

224. Man came to hospital with vomiting and dizzy after he ingested toxic dose of
certain drug, what is the most important step? watch the vital signs and
make them normal

225. Drug makes urine Red? " Rifampicin - Phenazopyridine - Senna -

Doxorubicin "

226.Drug makes urine Brown? Nitrofurantoin ( Metronidazole -- dark urine

)

227. Drugs are stored in the body in? fat & protein (1) , fat only (2)

228. If drug has the same active ingredient like other drug but not contain the same
inactive ingredients? ( Pharmaceutical Equivalent )

229. The ethical principle of veracity equires that? ( we act with honesty ,
without deception )

230. Principle of non-maleficence requires that pharmacist? ( do goods to

patients, placing Pt benefits above all else )

231. Style of management in which the owner of pharmacy emphasizes the

development of detailed policies and written procedures for employees to observe
at all times is referred to as?

( bureaucratic )

232. Pharmacist responsibility in hospital? ( deal with drug interactions )

233. Plasma concentration of drug in all body is? ( Distribution rate )

234. About steady state concentration during IV administration?

directly proportional to infusion rate & inversely proportional to total body
clearance

235. To compare between 2 drugs, use?

( pharmacokinetic parameters and pharmacdynamic parameters )

236. The 5 types of WBCs? neutrophils, eosinophils, basophils,

lymphocytes, and monocytes

237. The most common disintegrator in compressed tablet is? ( Starch )

238. Gums are used in tableting primarily as? ( Binding agents )

239. Why Solid dosage forms are better than solution dosage forms?

( accurate - easy to handle - more stable )

240. Liquid dosage form differs from solid in? ( easy in administration )

241. Most described dosage solid form? ( tablet )

242. Arrangement of electromagnetic waves in an increase ranking in air?

Alpha - Beta - Gamma

243. Examples of electromagnetic waves? ( X-ray and Gamma ray )

244. Hypertonic solutions can be adjusted by? ( make dilution by add more
solvent )

245. Enterohepatic recycling (EHR) is a feedback mechanism resulting from the

combined roles of the liver and intestine. EHR begins with drug absorption across
the intestine into the portal circulation, followed by uptake into the hepatocytes.
EHR depends on?

Dosage form - Extent of drug passed in feces - Gall bladder state

( except extent of drug absorption from stomach )

246. Drugs show multidrug resistance(MDR)? Anti-biotics & Anti-

cancer (in some cases anticancer drug show MDR)
247.Miscible liquids means those which can mix easily with or without stirring
which are least likely to be miscible? ( polar + non-polar )

248. The ability of liquid to dissolve in another liquid is called……?

( Miscibility )

249. Similar properties between solution and suspension : Both components be

separated from each other by physical processes - both are composed of 2 or more
components

250. In treatment of osteoporosis, hormone replacement therapy (HRT) is used

when other ttt fail

251. Which decrease the exposure to radiation?

increase distance from radiation source - put shelves - out from radiation place

(Wrong : decrease the activity of radiation person correct)

252. Drugs have different crystal structures so different in?

Polymorphism

253. Suspension eye drop differ than ophthalmic solution in?

( less commonly used & used for insoluble drugs )

254. Michaelis–Menten equation ? is enzyme kinetics law

255. Controlled released drug delivery depend on ?

( ready programmed & no influence of the body fluid )

256. Example of pathological toxicity ? ( hepatic necrosis from acetaminophen

= Paracetamol )

257. Amount of water in adult male is 60 % and in adult female is 55 %

258. Metabolism in intestine? ( hydrolysis )

259. DOC for anemic patient refuses to take injection? Oral Ferrous gluconate
N.B; iron sucrose is injection
260.

261.

262. The most commonly method used in the sterilization in our society?

( Autoclave 1st ) ,( dry heat 2nd )

263. Small group of medications in any health organization that medical staff deal
with them in caution and their loss from the place cause very serious problem so
there is special way to store and dispense them? ( High alert drugs )

264. Which is contra-indicated to all vaccines? ( CD4 less than 200 )

265. Which prevents neural tube defects "birth defect"? ( Folic acid )

266. Why creatinine is used as indicator for renal function?

( it's bound to protein that is only excreted by kidney )

267. Linear pharmacokinetics = First order = clearance don’t changed

268. Non Linear pharmacokinetics = Zero order

269. Cockcroft-Gault equation is used for glomerular filtration and is indicated

for…?

( chronic = bilateral renal failure )

270. Drug clearance ? ( elimination of drug from the body )

Clearance is defined as the rate of drug elimination divided by the plasma

concentration of the drug

271. Which may cause acute renal failure ? ( IV radiological substance )

272. What is effect of obesity on absorption of lipid soluble drug?

No effect on absorption but increase distribution volume

273. Baby with positive RSV test "Respiratory syncytial virus", chronic lung
disease, intervention?

IV fluids and supportive care

274. First pass effect? is a phenomenon of drug metabolism whereby the

concentration of a drug is greatly reduced before it reaches the systemic circulation
, blood that perfuse virtually all gastrointestinal tissue passes through the liver by
means of the hepatic renal vein

275. Toxiderm ? the syndromes are caused by toxin

276. T1/2 in first line is …..? 0.693 K

277. PH measures? ( Acidity )

278. If drug is eliminated by first order elimination , what determines when will it
reach steady state?

a.Half-life b.dose interval c.elimination rate d.drug dose

279. Acc to therapeutic index = therapeutic ratio , the larger therapeutic index
the drug is safer

280. Studies in which data is collected from different studies?

( Meta-analysis ) or ( Systematic review )

281. When you say on two drugs have the same bioequivalence?
( Pharmacokinetics parameters ) ADME

282. Aspartame is added to some preparation as …..? ( sweeting agent )

283. To avoid acute renal failure? ( maintain hydration )

284. Drugs cause heartburn ?

Potassium supplement as KCl - iron supplements - antibiotics - oral

bisphosphonate - quinidine - pain relievers

285. Ophthalmic preparations shouldn't have preservatives

286. Drugs cause hepatoxicity? Paracetamol - ketoconazole - rifampicin -

quinolones

287. Drugs is used for TTT of premature Ejaculation ? Dapoxetine

288. Which one in IV admix is ISO class 5 ? Cleanroom

289. Live vaccine and another inactive ? taken immediately

290. Which prevent bone fracture in osteoporosis? Ibandronate

291. TTT of Methemoglobinemia MMGE? Methylene blue 1-2 mg/Kg

292. What is avoided during using Methotrexate? Aspirin

293. Fat soluble vitamins K-E-D-A are important for ….? Liver

294. q.h.s = at bedtime

295. In elderly, what is Physiological effect of drug distribution?

increase lipid sol & decrease water sol drugs

296. Drug will be more absorbed in presence of H2 blocker as Ranitidine

"increase dissolution rate" ? Naproxen

Concomitant administration of H2 blockers may increase the dissolution rate of

enteric –coated naproxen, causing the drug to be released in the stomach instead of
the small intestine
297. What is cytochrome subtype responsible for drug interaction between
omeprazole and clopidogril? CYP2C19

298. What are pharmacokinetic parameters studied for drug before it to patient and
for estimation of dose in DAT patient ? bioequivalence studies

299. What is the parameter used in pharmacokinetics to assess the renal function?
CrCl

300. Which drug has increasing oral bioavailability when broken from big particle
to small particle? dissolution rate limited

301. In obese patient, the lipid soluble drug = drug distribution will? increase

302. What should we do when administration rate = elimination rate ? same

dose

303. How many t 1/2 needed to eliminate 99% of drug after single dose? At what
time 99% of the drug will be cleared from the plasma? 6.6 T half

304. Which organ/tissue contributes for two compartments of drug distribution?

adipose tissue

305. Anti-depressant Selective serotonin reuptake inhibitors (SSRIs) Citalopram ,

maximum dose in elderly over 60 years old is 20 mg/day due to QT prolongation ,
what can be problematic with iron supplement in elderly? Absorption

306. 85 year old women is taking ferrous sulphate to treat an iron deficiency
anemia. Changes in which of the following pharmacokinetic properties associated
with aging can most affect this agent?

a. absorption b.distridution c. metabolism d. renal elimination

307.All the following patients are seeing their pediatrician today and are due for
immunizations on the basis of the routine schedule. For which one of the following
patients would it be best to recommend deferring immunizations until later?

a. 12 month old boy who recently completed a cycle of chemotherapy for acute
lymphocytic leukemia.

b. 6 month old girl receiving amoxicillin for otitis media.

c. 12 month old HIV positive boy who’s most recent CD4 count was greater than
1000.

d. 12 year old girl completing a prednisone burst ( 1 mg/kg/day for 5 days) for
asthma exacerbation.

308. A 2 year old child came to clinic for taking hepatitis A vaccine, we know that
he took pneumonia vaccine from month ago, so we should:

Give him the vaccine immediately

309. A nurse was giving the medication to a hepatitis B patient when she got
infected with his blood, when she made analysis the result was HBSAG negative
and HBSAB negative , so she should be treated with:

Give her immunoglobulin + Hepatitis B vaccine

310. A pregnant women has Hepatitis B when she delivers we must give her baby:

Hepatitis B vaccine with immunoglobulin hepatitis

311. A kidney failure patient with hyperkalemia which of the following should be
used

a. insulin

b. thiazide diuretic

c. calcium gluconate (or Ca carbonate)

NB

*Due to the DOC in case of renal failure is loop diuretic not thiazides

*calcium is used as prophylaxis of arrhymia due to hyperkalemia

* calcium gluconate or Ca carbonate both are right

312. A 2 year old child has taken Hepatitis A vaccine and came to take MMR

Vaccine

Should take MMR vaccine immediately

313. A pregnant women in her 9 th month, she has hyperproteinemia and
hypertension. What is the recommended medication for her?

MgSO4

NB:

*This case called “Eclampsia” characterized by HTN + hyperproteinemia

* MgSO4 used to treat seizures not for HTN

314. A women with septic shock….came tp emergency who take ABC(airway,

breathing and circulation)

HR=122, BP=90/70 mmHg, serum creatinine=6, Na and Cl very high than normal
range and high pulse. What should she take?

a.albumin 5% bolus b.NaCl saline c. furosemide d.dopamine

315. A patient has septic shock and his BP 70/40 mmHg, a slight increase in K
level and Na within normal range…which drug should be recommended for him?

a. dopamine b. furosemide c.saline d.albumin

NB:

Severe septic shock , we recommend IV fluids (1) then

dopamine (2)( also DOC in case of septic shock with normal sodium + kidney
injury)

Anaphylactic shock = epinephrine

Cardiac shock = dopamine

316.Prevents neural tube defect (NTD) in fetus? Folic acid

317.analysis for man 65 year renal failure

Result

Sodium =110 (normal 135-145 mEq/L)

Potassium=9(normal3.5-5.5 mEq/L)

Urea=54 (normal 35-40)

Serum creatinine=10(upto 3.5) …..which of the following?

a.0.22% NaCl saline 500ml/hr

b.0.9% NaCl saline 500ml/hr

c. MgSO4

318.A patient takes multivitamin and his lab results show high K,high BUN and
serum Cr…..what is the cause of these results? Renal insufficiency

319. A summary of a case that a patient suffers from headache, nausea, vomiting
and blurred vision.he went to a hospital with alcohol toxicity(methanol) and did
kidney and liver analysis.his results and the normal range of the tests have shown
to you….all results about to be normal….the question is….what is your
recommendation for methanol toxicity?

a. vomiting and nausea

b.vertigo and vomiting

c. blurred vision

d. lab results

320. A child is born to hepatitis B positive mother?

a. first dose of the hepatitis B vaccine

b. one dose of the hepatitis B immune globulin (HBIG)

c. Both of them
321. A patient’s Cr clearance is 70% what should we do with the drug dose which
eliminated by kidney?

Decrease the dose by 30%(NB: if Cr clearance is 30% then decrease the dose by
70% )

322. A girl 16 year has DM type 1 and she takes insulin in specific medical
schedule…she take pioglitazone with insulin according to instructions of her
doctor from 2 month ago….she complain nausea and vomiting from two days as
she escaped from the schedule…she made lab tests and you have shown her results
in details….some of her results:

HR=110, BP=80/50….initially you give her?

0.9 NS in 500 ml solution

323. Category X

Studies in animals or humans have demonstrated fetal abnormalities and/or there is

positive evidence of human fetal risk based on adverse reaction data from
investigational or marketing experience, and the risks involved in use of the drug
in pregnant women clearly outweighs any possible benefit. The drug is CI in
women who are or may become pregnant.

324. when should women change her pregnant pills?

It is needed to be changed even she doesn’t forget to use pills

325.ttt for BPH…..? alpha adrenergic blocker(1)………..alpha reductase

inhibitor(prostste size greater than 40gm)(2)
326. A dyslipidemia patient has IHD…..CI with this case? Celecoxib

327.48 years man he took pneumococcal with influenza vaccines, which vaccine
should take next? Influenza

328.Lithium and gentamycin can be measured and curved down after? 8hrs(TDM)

329.warfarin antidepressant drug interaction?

decrease warfarin metabolism, increase plasma level

330. old patient end stage colorectal cancer take 60mg morphine twice. Suffer pain
when he go to bathroom add? Mg

331. category B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there
are no adequate and well controlled studies in pregnant women

332. child receive high dose amoxicillin for otitis media and he has appointment
for vaccine what we do shall we postponed the vaccination? No

333. speed of response of receptors( receptor response in milliseconds and other

receptor respond in seconds)? Ligand gated receptors and G protein receptors

334. category A ? no evidence of any risk on human and animals

335. A child swallowed 100 capsules of iron each capsule contains 18 mg , no

signs and symptoms ,so the ttt is? Gastric lavage

336. Vaccine CI in pregnancy

337. Case of 45 year patient with kidney failure from 2 year ago with increased K
and life threatening arrhythmia, the patient should be treated with? Calcium
chloride IV

338. Iodine contrast medium for patient who have diabetes and take metformin,
glipizide and have normal ranal function?

Stop taking metformin before the exam and not to begin using it again until 48
hours after exam

339. drug not cross placenta? Insulin

340. Child patient start course of antibiotics he take the drug for seven days and
still one dose and he have to take vaccine? Take vaccine immediately

341. TDM aim is to? Individualize pharmacokinetic parameter

342. what kind of error for dose more or less than prescribed? Improper dose
error

343. Dr. want to know about interactions between garlic and drug, he should read?

344. Dr. prescribe chlorpheniramine for a driver but the pharmacist discover a
problem?

The error occur and drug won’t reach the patient

345. After dispensing drug the pharmacist find mistakes, what should do? Patient
who received the drug

346. non formulary drugs are dispensed to? Inpatient(indoor patient)

347. drug waiting to be registered in saudi drug committee? Non formulary drug
348. all these drugs are controlled drugs except?

a.carbamazepine b.rivotril c.tylenol d.diazepam e.fosamax

349. Patient adult has vaccinated in 2010 against influenza, 2011 against influenza,
2012 against meningococcal, 2012 against influenza, 2013 against meningococcal,
what is the vaccine should take now? Influenza

350. Formulating of the drug is done by? Drug therapeutic committee

351. If a lactating mother has less milk production, what are the effects on nursing
infant? Diminished weight gain

352.Non formulary drugs given to? Non affordable patient

353. drug decrease dopamine action? Amlodipine

354. OTC medications

355.interaction between 2 or more drugs, known as? Drug-drug interaction

356. Process of using the drug is? One of the following is a component of drug
processes ? administration

357. A hospital on formulating drug, efficacy, work overload, and costs are taken
in concern, A, B, C, D and E are antifungal drug available in the market. All have
the same efficacy. The hospital was using drug E for a period of time. According to
the following data which drug is best to be used by the hospital: DRUG COST
FREQUENCY DURATION

a-3.25 BID 14 DAYS b-2.25 ONCE DAILY 14 DAYS c-5.5 BID 7

DAYS d-2.25 BID 7 DAYS

358.at 250C ,benzoic acid is much more soluble in benzene than it is in water. In
this situation benzoic acid could be considered to be ? non polar
359. African American women take lisinopril and another hypertensive drug suffer
from nose swelling and other symptoms what make her more suspected to this
reaction?

Ethnicity(1)…………drug combination(2)

360. Very small molecule(1 part ) soluble in more than 10,000 part of water?
Insoluble

360. “Protect from light” in USP means? Amber glass

(N.B if question asked in USP the answer is amber glass ,if not …….the answer
is “Light resistant container” )

361. narrow therapeutic index(NTI) means the ratio between LD50 and ED50 is
small

NTI = more dangerous

Eg: digoxin, phenytoin, lithium, theophyllin, etc

362. drugs that physician should care when using it ? low therapeutic index
drugs

363. Bioavailability? Area Under the Curve

364. A drug has dose –dependent according to pharmacokinetic parameter?

Phenytoin
365. Vitamine CI in pregnancy in highly doses? Vitamin A

366. amantadine ? antiviral and antiparkinsonian

367.

368.

369. In high therapeutic index:-

a-more toxicity
b-no side effects
c. The drug is less likely to cause serious side effects

370. which of the following is not fungus:-

a-mushroom
b-E.coli

371. charcoal:-
a-adsorbant
b-absorbant

372. in pregnancy all are avoided except:-

a-phenytoin
b-phenobarbital
c-valproic acid
d-clonazepam

373. which is true about dry gum emulsion:-

a-ratio 4:2:1
b-water gum and oil are added together and triturated slowly
c-oil and gum are triturated and water added slowly.
d-non of the above
e- gum and oil are added together and triturated then add water at once

NOTE: (wet gum emulsion: water and gum are triturated and oil added slowly +
4:2:1 ratio)

374. emulsion inversion:

a-conversion of W/O emulsion to O/w emulsion and vice versa

375. electrical conductivity is a feature of (or something like that)

a-W/O emulsion
b-O/w emulsion

376. velocity in dispersed phase affected by:-

a-particle size
b-particle homogeneity
c-electric charge
d-all

377. Cmax stand for:-

the maximum conc that drug conc reach

378. Tmax stand for:-

time at which plasma concentration reach maximum
379.

i. from diagram, the drug is completely cleared form body after:-

24hr
ii. Tmax in this chart equal :3hr

380. the drug conc above MTC indicate for

a-toxicity
b-side effect

381. drug below MEC

a-ineffective
b-toxic

382. MTC means

a- Maximum toxic conc.
b- Maximum safe conc.
c- Minimum toxic conc.

383. particles size affects:

A.Dissolution
B. Uniformity in the tablets(homogenicity)
C. solubility
D. ALL

384. IV in emergency: except

A. The fastest and the standard in Er
B. good for titrating the dose
C. safest and convenient for the patient

385. Foam in pharmacy found as spray used for :

a. Burn dressing and topical but not for rectal administration
b. Topical and rectal but not for burns
c. Topical, rectal and for burn dressing✔
d. Topical only

386. Conductivity test – Dilution test – Dye test used for which dosage form :
a. Susp.
b. Emulsion
c. Foam
d. Gel

387. Bacteria move by :

a. Pilli
b. Flagella

388. Adipose tissue and skeletal glucose transporter : GLUT4

389. We avoid extreme change in temperature in emulsions? Why avoid change

temperature in emulsion ? to avoid cracking

390. Two hydrophobic particles with opposite charge mixed with water this is?
emulsification

391. Not typical coating for tablet?

volatile coating

392. Tablet not using disintegrating, lubricant agent?

effervesant tablet
393. kwashiorkor syndrome is deficiency of? protein

394. Acidic drug carrier in plasma is ? albumin

395. Pharmaceutical equivalent EXCEPT ?

a. chemical form
b. dosage form
c. conc
d. same AUC & extent

e. have same rate of extent and bioequivalence

396. Refregerator temperature is ? 2-80C

397. titanium Dioxide used in sunscreen for ?

a. Reflect the UV

b. Absorb the UV
c. Humectants agent

398.medicine can be Sold? Patient came to the pharmacy, he was angry and
shouting he want to buy a medicine but as a pharmacist following the roles only
can give (medicine Sold)

a-in Original Packet

b-if part is given it should be include the batch no, drug name and expiry date
c-if part is given a copy of the leaflet should be given to pt
d. pack
e. strip
f-All
399. For tablet preparation all can be used except :
a- Wet granulation method
b- Dry granulation method
c- direct Compressed
d- Indirect compressed
400. Patient taking INH,Methotrexate and amiodarone What he may have as side
effect of these medications ?
a-Pancytopenia,

b- liver cirrhosis(or Hepatotoxicity)

401. MTC mean: minimum toxic concentration or maximum safe

concentration

402. MEC mean : minimum effective concentration

403. clinical use therapeutic range : between MTC & MEC

404.AUC:area under the plot ofconcentration- time curve

405.

a. T max of IV curve : zero

b. Tmax of oral curve : 4 hr
c. Assume zero order for iv curve what will be the t half = 12hr
a. (since he said Zero order…but if first order t1/2 will be 4hr)
d. The colored area reflect : AUC
e. Which is true: Onset of IV is faster than oral
f. Cmax: maximum concentration of the drug to reach maximum effect
g. Tmax: time required to reach maximum plasma concentration
h. AUC measured by: Trapezoidal method
i. clinical use therapeutic range ; between MTC & MEC
 j. iv onset : 0 hr
k. oral onset: 4 hr

406.Which of these drugs contraindicated in Pregnancy:

a. tinzaparin b. Ganciclovir c. Methyldopa

407. Which of the following is NOT a drug metabolizing enzyme?

a. CYP 3A4 b. CYP 450

c. UDP-GTN-acetyl transferase d. Alcohol dehydrogenase

408.Advantages of IV route over oral route:

1- safe and convenient, rapid onset, dose can be titrated, can be used in ER

2- safe and convenient, can be used in ER

3- rapid onset, dose can be titrated, can be used in ER

4- rapid onset, can be used in ER

409. High risk of nosocomial infection?

a. Surgery b. mechanicalventilator c. hospitalized >10 days d.Health care staff

410.laminar airflow hood is cleaned by?

a. Alcohol b. bleaching tablet c. ammonia d.soap and hot

water

411. Cataplexy is (the case was about narcolepsy and cataplexy):

a. Seizure b. Increase muscle tone c. Sudden and total loss of muscle
tone

412. Which one of the following is not a chelate?

a. Hemoglobin b. Lactulose c. Amikacind. cisplatin

413. What is true about Lactulose? laxative decrease ammonia levels in

hepatitis
414. Study about cell mediated immunity?
a. T Cell or T-lymphocytes b. IgG c. IgM d. IgE

415. Treatment of hiccup?

a.baclofen b. Chlorphenamine

Note: we can use also: typical antipsychotics- metoclopramide and muscle

relaxants to treat hiccups

416. vaccines document kept for:?

a. min. 2 yrs b.min. 3 yrs c.min. 5 yrs

417. Meaning of high therapeutic index? no SE or less SE or low SE

418. meningitis caused by gram negative? patient have Neisseria meningitis and
his CSF analysis reviewed a gram negative bacteria?
a. Hemophilus influenza b. Streptococcus c. Mycobacterium tb

419. Albumin highly bind to ? a. Weak Acid b. Weak base

420. cold cream: a. w/o b. o/w

421. side effect of tetracycline, furosemide and corticosteroids? acute

pancreatitis

422. To achieve max bioavailability ،if ph = 5.2 (slight acidic) the best
pharmaceutical form is? A drug degrades at pH=5.5, traverse muco-cutaneous
membranes. Which of the following preparations should be used to ensure
maximum bioavailability?
a) IV solution
b) Capsule
c) Suspension
d) Aerosol

423. the expiration date on original package NOV 2015 today is 1 DEC 2014, the
pharmacist repackaged the medicine with FDA guidelines :25% of remaining time
on the original package to max. 6 months what is the new expiration date?
FEB 2015

NOTE:IF they didn’t mention 25% then answer will be MAY 2015

424. blood transfusion which element make liver toxicity: Iron

425. Patient came to the pharmacy; he was angry and shouting he want to buy a
medicine but as a pharmacist following the roles only can give (medicine Sold)?

a. Original Packet b. packleaflet c. strip d. ALL

426. All of the following are NOT activated receptors except:

a- Cholestyramine b- AL. OH c- Mannitol

d- Neostigmine ( reversible Acetylcholinesterase inhibitor)

427. Case of patient had injury and result in HIB from previously 6 months what is
the least effective in his case:?

a. Interferon alone b.Vaccine

must be given with 24 hours to maximum of 7 days after exposure

428. A case associated with hepatic failure? Ascites

429. Aspartame not given with patient who has?

a. phenylketonuria b.phenylketoanemia

430. Corn is:Too much pressure on illy fitted foots

431. Which of the following parameters you CANNOT overcome by making

prodrug:Potency

432. Patient has glutamate allergy he suffers from:Caeolic disease

433. Pretender to medicineskill called: Quackery

434. Most drugs are:

a- Strong electrolytes b- Weak electrolytes

c- Non electrolytes d- Highly ionic e- None of the above

435. Which part of the can considered as the heart of the can?

a.valve or actuator b.propellent c. tube

436. Which part in aerosol press on valve?

a. Actuator b. House c. Dip tube

437. Which of the following gases are used as a propellant in aerosol container?

a.nitrogen b.carbon dioxide c. nitrous oxide d.all

other liquified gases include: fluorinated & Fluoro-chlorinated hydrocarbons

other commonly used are: dichloro-difluoro-&methane-trichloro-mono-fluoro-
methane

438. 38-Case of a patient asked for an OTC for her constipation, she said that
she experienced painful defecation. you decided to transfer her to a physician
because you think she has:
a.Anal fissure b.Anal fistula c.Rectal fissure d. Rectal abscess

439. patient came to pharmacy and bought a UTI indicator test, which of the
following is true?
A.it’s a test that convert dietary nitrite to nitrous
B. it’s a test that indicate anaerobic bacteria only
C.it’s a case that indicate gram positive bacteria only
D.it’s a kit that contains 30 dipstick in a packet

440. How to differentiate between kidney failure & rejection of a kidney

transplant?
A.Creatinine clearance test B.glomerular filtration rate
C. albumin test D.calcitonin clearance

441. Whichof the following is NOT colloid solution?

A.albumin5% B. ringer`s solution C.dextran D.beta-starch

442. 48-Female Patient having osteoporosis, wants to initiate a treatment,

which of the following is NOT true?
A.Alendronate should be taken 60 min. Before breakfast
b.hormone replacement therapy should be considered
c. Ca and vit. D is essential
D.outcome should be assessed with periodic bone density
E.raloxifene is selective oestrogen modulator

443. Which of the following drug interactions is not used therapeutically?

a- Epinephrine / Lidocaine b- Probenecid / Penicillin
c- Pseudoephedrine / Salbutamol d- Trimethoprim / Sulphamethoxazole

444. Which of the following is the main domain in producing gastric acid?
a. Histamine b.gastrin

445. Which is not essential amino acid:

a. Threonine b. Tryptophan c. Glutamate d. Methionine

446. pateint come to pharmacy ask about his hand, he has grey burrow's on
web?
a. scabies b. psoriasis

447. Major pathway of excretion of Calcium is?

a. Kidney b. Gut c. Kidney and Gut d. None of the above

448. normal prescription valid for?

a. no limit b. 6 month c. 9 months d. 1 year

449. where histamine is stored in the GIT?

a. Basophiles b. Parietal cells c. Enterochromaffin cell

Note: histamine release from Enterochromaffin-like cells

Note: Enterochromaffin-like cells release Histamine which binds to H2-receptors
and stimulates parietal cells to secrete Gastric acids.

450. All of the following drugs are avoided with azathioprine except?
a. Propranolol b. Allopurinol c. Enalapril d. mycophenolate mofetil
NB.
Avoid the use of azathioprine with
BCG, Febuxostat, Mercaptopurine, Natalizumab, Pimecrolimus, Tacrolimus,
Tofacitinib, Leflunomide, 5 ASA, Ace inhibitors, Allopurinol, Denosumab,
Ribavirin, Roflumilast, Sulfamethoxzole, Trastuzumab, Trimethoprim,
Coccidioidin, Sipuleucel t, Vaccines, Vitmin k antagonist

451. The metabolic effect of combining glucocorticoid and tacrolimus is?

a. Hypocalcemia b. Hyperglycemia c. Hyperlipidemia d. Hyponatremia

452. Affect dissolution rate, absorption rate, content uniformity and stability?
a. particle size b. size distribution c. interaction with surface molecule

453. A chronic condition characterized by epidermal hyperplasia and hyperplasia

turn over with red scaly lesions? A skin condition characterized by red scaly
patches?

a. Acne b. Psoriasis c. Erythematosus d. Eczema

454. bacteroids are: irregularly shaped form of a nitrogen-fixing bacterium (such as

a rhizobium) found especially in root nodules of legumes

455. Most dangerous life-threatening seizure should go to emergency? Status

epilepticus

456. to distinguish and differentiate between o/w or w/o we use?

a. Miscibility test b. Conductivity test c. Staining test d. All

457. hypodermal injection?

a. Under skin b. in muscles

458.flat, scale like, multilayered? Stratified squamous epithelia

459. not test of stability of emulsions?

a.miscellization b. globular size c. centrifugation d. viscosity test

460.histamine autorecepteor:H3

-Glut 1-ERYTHROCYTES, mast cells, brain and heart, vessels

-Glut 2- kidney, liver, pancreas and intestine
-Glut 3- neurons and placenta
-Glut 4-fat and adipose tissue +skeletal muscles
461. patient with HBV infection after few months of needle exposure which is
least effective?

a. HBV vaccine b. Interferon

462. patient Experienced oliguria, the best way to treat oliguria? Hydration

463. immune serum globulin usually taken?

a. IM1st b. SC c. IV

( by all route )

464. small size suspension not taken? IV

465. Patient with allergy conjunctivitis using lens?

Neither gas permeable lenses nor soft lens should wear during apply eye drop.

466. In which phase of drug investigation is the efficacy and the dose of drug
determined to be used in further trials?

a. Phase 1 b. Phase 2 c. Phase4 d. phase3

Pre-clinical  on animals pharmacology and toxicology
Phase 1 Determination drug effect on healthy volunteers
Phase 2 Determination dose +efficacy +Side effects on ptn with disease or
condition
Phase 3 large scale multi centered study
Phase4 After FDA submission +Side effects post marketing +Safety
Phase 5FDA approval on the modification

467. Pubmed definition:Database that access Medline freely and concern

about science researches and biomedical life.
Note: The other choices are about chargable or for specific person

468. Which medications can be dispensed without a prescription?

a) Aspirin 81 mg b) Decussate sodium 100 mg 5tab
c) Loratadine 10mg tab d) ALL

469.Which are examples of situations when a pharmacist should not dispense

a prescription?
a) Pharmacist suspects fraud or cheating.
b) Pharmacist thinks the medication might harm the patient
c) Pharmacist doesn’t know the doctor
d) ALL

470. Which is not a responsibility of HAAD?

a) Pharmacy b) Drug store c) Scientific Office d) Door to door pharmacy

471. What is a pharmaceutical alternative?

a. Drug products that contain the same therapeutic moiety but as different salts,
esters, or complexes.
b. Drug products that contain the same therapeutic moiety but as different dosage.
c. same active moiety, different in solubility
d. same active moiety, different strength
e. different active moiety, same action

472. what is the definition of a formulary?

a. list of drugs to be used in hospital, clinics and pharmacies
b. An official list of drugs approved for prescription or administration to
patients of a hospital and clinic and pharmacy

473. what is the definition of Randomized clinical trials?

a- randomly assigning patients into study groups
b- randomly assigning treatment into patients
c- random segregation of patients upon treatment
d- randomly assigning physicians.

474. Which is appropriate when counselling for Isotretinoin?

a) The acne will get worse when you first start treatment, but after that it will get
better
b) Avoid sunlight as this medication will make your skin burn more easily
c) Your night vision may improve, as this medication contains vitamin A
d) Avoid pregnancy

475. Which is a prodrug? DRUG is enzyme inhibitor in the primary action?

a- Enalapril b- captopril

476. Which of the following is considered as illegal?

a) Asking a demographic question for a patient with hypertension
b) Discussing a rare genetic disease case of a patient with other colleagues in the
cafeteria
c) Advising a patient to see a consultant because you think the treatment given by
his resident is ineffective

477. Which medicine causes steatorrhea?

a. orlistat(known asTetrahydrolipstatin)
b. simvastatin

478. counsel for orlistat? Change life style,cause steatorrhea, Inform him
about diet and life style

479. Bioavailability F= 1-E refers to?

a-elimination rate b-extraction ratio C-excretion rate d- ALL

480. RX: Timolol 25% eye drop, S: i.o.d. BID, M: 15 ml. on prescription label
should read as:

a- apply 1 drop into both eyes twice daily

b- apply 1 drop into left eye twice daily
c- apply 1 drop into right eye twice daily
d- shake will and install drop into left eye twice daily
Note: Eye  O Ear a Right= d , Left=s , Both= u
STAT=Immediately, BID= twice , TID= Three times , QID=4 time ,
Q.d= Each day, QOD=Every other day , SOS=If necessary

481. Which is NOT an example of adulteration?

a-Wrong number of pills in a bottle

b-Change in the tab expeint
c-Manufacture change the dose

482. Which of these are enzyme inducers?

a) Phenobarbital b) Cimetidine c) carbamazepine d) erythromycin

 Common Cytochrome inducers are:
 Phenytoin, Phenobarbital (Barbiturates)
 Theophylline
 Carbamazepine
 Alcohol
 Rifampin
 Oral contraceptives
 Griseofulvin
 Common Cytochrome inhibitors are:
o Azoles
o Clofibrate
o Erythromycin
o Allopurinol
o Chloramphenicol
o INH
o Cimetidine

483. Metabolism of ethanol?

a) Cyp450 b) alcohol dehydrogenase c) glucuronide d) all

484. Junior pharmacist new one, he asks about Refill?

narcotic prescription must be dispensed under restrict condition

485. about the insecticides as DIFP, which increase the transdermal
absorption??
A- High lipid solubility B- High molecular wt. C- Volatility D- A+B

486. To know the patient, understand how to use drug: when use medicine

487. If two drugs are pharmaceutically equivalent which statement is not true:
a. they have the same active ingredient b. they have same dosage form
c. they have same route of administration c. they are bioequivalent

488. generic drug means?

a. Have the same active ingredient +same as original brand, Chemical name of
b. the Brand drug not under protection of generator company
c. Drug not manufactured by the generator company
d. drug not under the protection of parent company to manufacture alone
e. drug manufactured by other companies other than parent company

489. about facilitated diffusion ?

down gradient + protein carrier+ similar to P-glycoprotein found in the

intestine

490. Primary Active transport needs: Hydrolysis of ATP

Note: Active transport (from low to high against gradient and need energy)
Passive diffusion:(from high to low gradient and no need energy) if adding
transporterFacilitated
secondary active transport: Ion-down gradient +another molecule or ion-against
gradient (e.g.: Na/Glu pump)

491. nephroprotective immune suppressant?

a. sirolimus b. tacrolimus
492. Vaccine for elderly people that is given yearly for respiratory? For elderly
patient with chronic respiratory condition, which vaccine usually recommended on
yearly basis?
a- influenza vaccine
b- Pneumocccous vaccine
C-meningococcal vaccine

493. About missed or broken ampoule. How to keep them in HAAD section in
pharmacy?
a-use the facility (incidence form) and send to HAAD
b-put them in disposal bag c- ship them in secured bag

494. What is the pore size of Littre for cold sterilization: 0.22micron

495. what is the lowest degree in refrigerator :2 0C

Cool temperature: 8-15 Cold temperature:2-8 Room temperature: 15-25

495. Saline flush is used for?

Small volume of saline is used to flush active drug into circulation

496. If the bioavailability of drug is decreased due to interaction with other

drugs what is true?

a. Higher doses needed or dose of this drug may need to be increased

b. change route
c. stop medication
d. absorption of the drug increase
e. renal excretion of the drug increase
f. metabolism of the drug decrease
467. which is associated with symptoms before rash and lesions: Cold sore

468. Which have narrow therapeutic index:

A -vancomycin, alprazolam, heparin
B -Heparin, warfarin, vancomycin, digoxin
C –warfarin, heparin, alprazolam

469. which route of administration is not used with parenteral suspensions?

a. IV b. IM c. intradermal

470. Which of the following is direct method test of non-compliance?

a. Pill count indirect b. Computerization indirect

c. patient interview indirect c. Marker or trace

471. An indirect test for calculating bacteria?

a. coulter counter direct b. colorimeter test

472. Sodium lauryl sulphate is used as?

a. antifoaming b. Antioxidant c. Solubilizing agent

Note: solubilizing, surfactant, foaming, cleanings, wetting, detergent

473. not tests of stability of emulsions?

a. Micellization b. Globular size c. Centrifugation d. Viscosity test

474. The filler that help in dispersing and mixing well or strengthening the
component?

a. Sugar b. Titanium dioxide

475. the glidant is?

a. sugar b. talc

476. Role of silica gel sachet?

a. Binder b. hygroscopic c. lubrication d. glidant agent

477. which is a fundamental test for new drug:

a-Ionization and purity b-Dissociation Constant and intrinsic solubility

c-Intrinsic solubility and polymorphism

478. benzyl alcohol is added to medical prep. As?

a. Diluent b. emulsifier c. preservative d. solvent

479. pt take tetracycline and antacid the best advice for him?

2 hours intervals between the 2 medications

480. Which one is not used for pregnant woman with haemorrhoids?

A. witch hazel B. lidocaine C. hydrocortisone D. Bismuth subsalicylate

481. you found that they issued an expired medication from your stock. what
is your action?

a. call and inform the prescriber

b. document the medication error to haad

c. Try to contact ptn to return medication

482. a regular customer to your pharmacy came with a RX but from your
record u discovered, a drug-drug interaction between the new and the old
medications. what is your best action?
A. refuse to issue the RX
B. tell the ptn about the drug interaction and send him to the doctor
C. call the doctor and tell him to change the drug to avoid interaction

483. INH, amiodarone & MTX common S.E?

a. Heart failure b. Cirrhosis c. Pancytopenia d. Pulmonary problem

484. high temp is avoided in emulsion to prevent: Cracking

485. aggregation of oil droplets on glass after shaking it disappears (emulsion)

Creaming
486. Oil droplets on surface of emulsion and when mixed become homogenous
what is it called? Emulsion preparation and it is homogenous but with oil droplet
on the glass ,The emulsion will reform on shaking this is called: ( this as
segregation of the low density particles at the top on the glass so?
Creaming

487. +ve & - ve particles mixed together with water what is called?
Emulsification

488. 2 hydrophilic/hydrophobic particles mixed with water in presence of

emulsifying agent called: Emulsification

489. If an emulsion is able to conduct electricity then the dispersion phase is

probably:
a. Aqueous b. Non-Aqueous c. Low – lipophilic d. Hydrophilic

490. which is not quantitative?

a. safety b. affinity c. potency

491. Which of the following is anaerobic bacteria?

Clostridium sopranges, Clostridium perfringens

492. About those medications that have confusing route of administration

what you should do?
a. Return prescription to dr
b. Change expiry of the drug on the shelf
c. Add details and instructions about different route of administration in the
prescription

493. not used in dandruff

a. permethrin b. Selenium Sulphide c. ketoconazole d. Salicylic acid

494. two equal drug used together what their action called?

a. addition b. Synergistic

495. histamin not secreted from:

a. epithelial cells
b. SC fatty tissue
c. peripheral neurons
d. stomach

496. In preparing ideal aqueous tablets coating cannot use: Volatile solvent

497. to determine professionality of the pharmacy? Inventory Turn over

498. All can be as a Coat of tablet except?

a. Solvent b. Effervescent c. volatile

499. Poliomyelitis Vaccine? inactivated (dead) poliovirus

(it has both live attenuated and inactivated but the live attenuated associated with
higher risk to develop the infection so mainly used the inactivated form is used)

500. Which of the following need referral to doctor?

A- Diabetic patient with diarrhea more than 36 hrs.
B- 8 years old child with diarrhea more than 36 hrs. and fever (38°C)
C- Adult with diarrhea more than 4 days.

d. All

501. Saline flush, which is the best statement to describe:

a. Insert drug into blood circulation

b. Flush the face and body

c. Dilute drugs then insert in the blood

502. Must avoid Gluten, people who have which diseases? Coeliac disease

503. in highly polar compound like mannitol elimination rate equal to?

a. absorption b. excretion c. distribution

504. Drug that promote hyperglycaemia in DM except?

a. NSAID b. nicotinic acid c. diuretic d. opioid
505. International drug compendium?
a. Martindale b. Merck manual c. chemical abstract

506. Electronic database? Medscape

507. Primary clinical data, the pharmacist can find in?

a. Abstract b. journal or literature

508. How can you get medication information resource?

a. literature b. chemical abstract, international
c. pharmaceutical abstract d. Medline

509. RNA bonds are( 5' , 3' & hydroxyl or amide & hexose or ribose
sugar???):5’3’Hydroxyl + ribose sugar
510. pharmacist do self-inspection to the pharmacy except:
a. Sign it by himself b. Send report to HAAD
NOTE:Document and keep in pharmacy in a file Let pharmacy owner sign it

511. IV solution in patient in the hospital become cloudy?

a. warm it b. stops it c. complete it d. slow infusion

512. Promethazine is alkaline drug:

a. increase absorption in stomach b. increase ionization in intestine
c. increase excretion in NaHCO3 d. increase excretion in NH4Cl

513. Used Drug when the mother is RH negative and her husband RH
positive?

RH Immunoglobulin

514. If drug have low bioavailability its mean?

a. low gastric absorption b. low metabolism

c. low renal excretion c. high dose must be taken

515. Regarding FDA Regulations, When the manufacturer (developer) must

register the item in FDA:
A- From the beginning-Raw material
B- Before you test in patient

C- Before you test it in human volunteers

D- Before you make a toxicology test in lab animals

516. After circulation of certain drug, it proven that it causes severe

haemorrhage the FDA decide to stop this circulation, this is called?
a. drug recall class I b. II c. II d. none of these

Drug recall classification: assigned by the FDA.

*Class I: potential for serious SE and death.
*Class II: potential for temporary or reversible SE or when serious SE are unlikely.
*Class III: not likely to cause serious SE

517. Drug suppresses T lymphocytes:

a) Etanercept (suppress TNF not T lymphocyte)
b) adalimumab
c) Infliximab(suppress TNF)
d) Cyclosporin2nd
e) Alefacept 1st

N.B Basiliximab and Daclizumab suppress T lymphocytes but not in choices.

Note: Etanercept- Adalimumab- Infliximab =Block Tumor necrosis factor (TNF)

Cyclosporin- Tacrolimus- Sirolimus = Block Calcineurin and subsequently
suppress T-Lymphocytes
Alefacept= Binds to CD4 on T-lymphocytes and used for Psoriasis ttt

518. Drug suppresses T lymphocytes:

a. Etanercept b. Abatacept c. Infliximab d. Adalimumab
All used for RA
N.B Basiliximab (Prevent organ
rejection) and Daclizumab (Multiple
sclerosis) suppress T-lymphocytes too
519. which of the following cause depression in T-lymphocyte:
Abatacept, Alefacept, Sirolimus, Basiliximab, Baclizumab

520. Topical treatment for hair loss(baldness) for 25 years old male:Minoxidil.

521. Female is menopause, she experiences hot flushes, developed spinal

osteoporosis which to use?

a. Alendronate b. Estrogen and progesterone c. progestin

Note :If there is no alderonate in choices, the answer will be (estrogen and
progesterone

522. Factors affect cerebro-spinal fluid (CSF) penetration Except:

a) lipid solubility b. water solubility
c. Molecular weight d. Plasma protein binding

523. A patient suffers from esophagus reflex, which additional symptoms if

happened the patient should be referred to cardiologist?

a) mild pain in arms

b) pain in central abdominal
c) pain that spread to jaws, neck, shoulders and arms

d) pain in iliac fossa

524. Pharmacist monitoring of drug dispensing and refill will give an idea
about?

a) Drug utilization b) Drug disposal c) Drug adherence

525. What’s the type of study that’s MOST reliable?

a) Cohort randomized trials b) Case study
c) Case report d) case series

526. What’s the type of study that’s LEAST reliable?

a) Cohort randomized b) Case study
c) Case report d) Case series

527. Manufacturer recall of medication from pharmacy is called:

a) Voluntary call b) Immediate recall c) involuntary call

528. Which Iron dose is questionable?

a. 120 mg for 20 kg child

b. 90 mg for 15 kg child
c. 21 mg for 7 kg infant
d. 30 mg for 6 kg infant

Note: For child: 1 kg 6mg infant: 1 kg 3mg

529. Carbon monoxide binds to?

a. hemoglobin b. myoglobin c. cytochrome oxidase d. all

530. What should be done to prevent aspiration pneumonia?

a. Elevation of the head b. Taking the antibiotics

531. Which of the following will not cyp450 of theophylline?

a. Carbamazepine b. Cimetidine c. Phenobarbital d. Smoking

532. Two oppositely charged hydrophobic mixed with water what will
happen?

Emulsification
533. Which is NOT a non-mast cell that produce histamine?
a. Adipose tissue b. CNS cells c. Epidermis d. GI cells

534. Zoledronic acid?

Bisphosphonate Derivative, used in osteoporosis, Hypercalcemia of malignancy, to

prevent skeletal fractures in patients with cancer like myeloma, or prostate cancer.

MOA:inhibits bone resorption via actions on osteoclasts.

535. Drugs excreted in milk should have:

a. High lipid solubility b. Low bioavailability

c. weak base d. Low protein binding

536. Drug cause photosensitivity?

a. ciprofloxacin b. Doxycycline c. fluoxetine d. all

Note: Photosensitivity inducers: Quinolones, tetracyclines, Thiazides, SSRI,

Chemotherapy, mycophenolate mofetil, corticosteroids, sulfasalazine, sulphonyl
urea

537. Bacteriostatic?
a. doxycycline b. Amoxicillin

MST-CHLOR=Macrolide-sulfonamides-tetracycline-chloramphenicol

538. Vit. C and aspirin?

vitamin acts as an antioxidant in the stomach to decrease aspirin-induced stomach
damage

539. Which of the following is true about ORILSTAT?

a. it inhibits absorption of dietary fat (Lipase inhibitor)
b. patient should consume about 30 % of fats in diet (not more than 30% fats in
daily total calorie)
c. no more than one dose should be taken in 24 hours
540. Immune serum globulin is usually administrated by which type of
injection?

a.IV b. IM c. SC d. ID e. all

541.Grape fruit should not be used with which of the following:

a.losartan b. omeprazole c.Nifedipine d. Levothyroxine

Grapefruit has significant interactions with

 Nifedipine Verapamil Felodipine =CCBs
 Amiodarone Cyclosporine Levothyroxine Buspirone
 Statins (Except: Rosuvastatin-Pravastatin-Fluvastatin)

542.Which is weak electrolyte?

a. urea b. ephedrine c.glucose

Note: NaCl is strong electrolyte

543.Worker has been injured with blood infected with hepatitis B. upon
analysis it shows he has HB surface antigen. the most proper action is:
a. give immunoglobulin b. give vaccine
c. give Ig and vaccine d. do nothing as its only surface antigen

544. Not used together?

a. Acitretin +UVB b. Acitretin + puva

c. Acitretin+psoralen+UVA d. MTX+UVA

545. A property of bulk forming laxative? bulk laxatives are gluten free

546. Patient travelling on plane, to prevent jet lag effect and help him sleep
use? melatonin

547. Epigastric pain relieved by eating: duodenal ulcer

548. In cryotherapy you need:30 d to see results in warts

Note:Podophyllin is used in wart treatment & it is: grey node around finger.
549. How can you manage the drug interaction between quinolone &
amiodarone?

a. Avoid quinolone b. monitor amiodarone

c. decrease amiodarone dose by 25%

550. As a pharmacist how can you know that a patient comes to your
pharmacy has a vision problem:
a. Wearing thick glasses b. Looking as doggy eyes

c. Wearing black glasses d. All of the above

551. All of the following are true except:

a. COPD is a progressive disease

b. COPD respond to bronchodilators

c. COPD respond to corticosteroids

d. Skeletal muscle dysfunction is a common and CHF are common complication

552. a state of consciousness involving focused attention and reduced

peripheral awareness? Hypnosis

553. The aim of auxiliary label is to?

provide additional information about a drug

554. if you have a ptn with hearing problem and you want to make it clear for
him about using the drug you add? Auxiliary label

555. if a foreigner ptn has come to your pharmacy you need to add to the
instructions? Auxiliary label

556. Ancient Indian medicine called? Ayurveda

557. The following is true about demulcent?

a. formula used for soothing mucous membranes

b. Can’t be used on a skin

(Demulcent: sooth mucous membrane/ Emollient: Skin)

558. The content of electrolytes in a solution is expressed by?

a. Grams b. Milliequivalents

559. The enzyme responsible for conversion of fibrinogen into fibrin?

a. Thrombin b. Antithrombin

560. Which are problems in counseling a healthcare with patient regarding?

A. Cultural b. verbal and nonverbal communication

c. Food Habits d. Religion e. all

561. which of the following is /are generalized seizures

a. tonic clonic seizures b. febrile seizures

c. status epilepticus d. absence seizures

562. the definition of hemostasis? the stopping of a flow of blood

563. the definition of hematinic?

nutrient required for the formation of blood cells in the process of hematopoiesis.
The main hematinics are iron, B12, and folate. Deficiency in hematinics can lead
to anemia

564. hematopoietic system?

The bodily system of organs and tissues involved in the production of blood.
primarily the bone marrow, spleen, tonsils, and lymph nodes

565. Hemorheology?
the science of the flow of blood in relation to the pressures, flow, volumes, and
resistances in blood vessels, especially in terms of blood viscosity and red blood
cell deformation in the microcirculation

566. The hemostatic system includes?

a. platelet aggregation b. platelet coagulation c. fibrinolysis
NOTE :

*medicine or vitamin or mineral as iron that increase hemoglobin conc. in blood ;

it is called----Hematinic .

*medicine that increase blood cell formation , it is called -------Hematopoietic ,

*medicine that improve blood viscosity ------ Hemorheologic

*medicine that comprises platelet aggregation and fibrinolysis-------Hemostatic

567. phenol is?

a. Carboxylic acid b. Carbolic acid (C6H5OH) c. Carbonic acid

568. which of the following is true about microemulsion?

a. It is a translucent thermodynamically stable
b. It is an opaque emulsion

569. which of the following is an antidote for radiation?

a. Safranine b. Anthranine c. Crystal violet d. Prussian blue

To treat thallium poisoning or radioactive cesium poisoning. and used for exposure
to radioactive material until the underlying type is determined. Often given with
mannitol or sorbitol to increase the speed it moves through the intestines

570. syrups can resist microbial growth because of?

a. Osmotic effect b. Antioxidant effect

(Evaporation of alcohol>Water = accumulates on surface No Bacterial growth)

571. the agent that can kill microbes in or on an object?

a. bactericide b. antiseptic c. disinfectant d. Detergent

572. the study of liquid?

a. Rheology b. Pharmacokinetics c. Pharmacodynamics

573. Target Total cholesterol in patient with MI?

a. 150 b. 100
normal<200 mg/dl

574. which of the following is considered to be effective in accidental drug

poisoning?

a. Activated charcoal b. universal antidote c. ipecac syrup

575. Alcohol may be incorporated at which of the following dermal

preparations?

a. lotions b. ointments c. supp.

576. The group of people which is more susceptible to diseases?

a. 62 years and above

577. Used as preservatives?

a. Na benzoate b. Methyl parabens

578. the antagonistic use of leukotriene antagonist followed with B2 agonist is:
Physiological antagonist

579. stimulate the antibody production? Salicylic acid

580. drug contain paracetamol and codeine:Need authorized prescriber

581. What holds back Vitamin E from being favorable as supplement?

a. causes diarrhea on regular dose

b. causes bone pain and hair loss in toxic doses

c. fat soluble and absorbed like water soluble vitamins

582. How can soriatane (Acitretin) best classified?

a. Psoriasis treatment b. Estrogen c. Progesterone

d. Ovulatory treatment e. Anabolic treatment

d. Ovulatory treatment e. Anabolic treatment

583. oral administration, the greatest amount of iron absorption occurs in the
a. ascending colon stomach b. Duodenum and upper jejunum

c. sigmoid colon d. transverse colon

e. stomach

584. patient injured by wire what question you ask

a. when did happen

b. was the wire dirty ( is the blade is clean or dirty )

c. did u take tetanus vaccines in last10 years.

d. Are you have allergy to any medicines

585. Psoriasis characterized by

a. redness and allergic reaction

b. silver scales

c. itching

d.red, allergic, itchy, white-silvery scaly

586. Difference in diagnosis between pyelonephritis and cystitis?

loin pain Fever pus in urine

587. for dry eye, you give all except?

a. vinyl alcohol E/D b. polyethylene glycol E/D

c. Chloramphenicol d. Tears

588. What is/are true of lactulose?

a. . It is an artificial sweetener (man-made BUT NOT sweetener)

b. It is a laxative

c. It decrease blood ammonialevels

589. isotretinoin is commonly employed in treatment which of the following?

Acne

590. The most serious potential consequence of ingestion of a liquid

hydrocarbon such as kerosene or gasoline is
(A)inactivation of hepatic enzymes

(B) the corrosive action of the poison

(C) the paralysis of peristaltic motion of the GI tract

(D) dissolution of the mucus coat of the oesophagus

(E) the aspiration of the poison into the respiratory tract

591. Which of following would be consider a level with normal range for
healthy adult?

Total cholesterol 175mg/dl

592. Patient should refer to doctor if he is:

a. Patients more than 60 years three times in six months

b. Patient previously Diagnosed with the same condition.

593. Vaccines?

a. Tamiflu b. Oseltamivir c. Vaxigrip d. BCG

594. Agent used in cancer and rheumatoid?

a. Methotrexate b. Infliximab

Methotrexate used in: Rheumatoid Arthritis, Crohns disease, Psoriasis & as

antimetabolite cytotoxic drug.

595. Iron is essential for?Oxygen transport

596. Elidel is CDB used in: atopic dermatitis

Pimecrolimus (immunomodulating agent of the calcineurin inhibitor class)

597. Methylcellulose are added to drops to increase intraocular contact time
to form:Lubricant

598. Vitamin A: derived from beta-carotene

599. When there is an announcement for a drug call what do you have to do
first thing:
a. Call the patient to stop taking the drug

b. Collect current stock and return back to store

c. Check the total cost of current stock

d. Check which patients received the drugs.
600. Minor burn patient advise him to put?

a. ice b. running water for 10 min.

601. Acute pancreatitis study collecting data from old records which type of
study is it
a. cohort b. case control study c. cross sectional d. census

602. Drug not to penetrate the breast milk?

a. Weak acid b. Low lipid solubility c. High lipid solubility

603. Swelling of one leg and pain can be a cause of?

a. D V thrombophlebitis b. CHF c. STROKE d. Osteoarthritis

604. A woman came to pharmacy seeking help as her baby crying during
plane descend, because of otitis media, she wants to prevent her baby next
time, the pharmacist can advise her:

a. Nursing her baby b. Suggest decongestant nasal spray

605. Grapefruit should be avoided in patient taking?

a. Valsartan b. Buspirone c. Felodipine

606. Lactase enzyme is commercially available for the treatment of?

a. Lactose intolerance b. crohn’s disease

607. Eye drop after opening should be used for?

a. 14 days b. 28 Days c. 7 days

608. Methimazole is week base (PKa 10.2) what the anti-dot?

NH4Cl(to acidify urine)

609. What is the hay fever?

a. Bacterial b. viral c. allergen

610. What the cause of spina bifida?Deficiency of folic acid

611. Which is used in film coating?Titanium oxide

612. DPT? Diphtheria-Pertussis- tetanus

613. Treatment of scabies‫؟‬permethrin

614. Why influenza virus should be taken yearly?

to cope with the different species of virus every year

615. Normal serum level of potassium?3.5-5 mmole/l

616. Which of these diseases caused by Papilloma virus‫؟‬Cervical cancer

617. Obesity: mass body index >30

618. Which of these drugs cause anaemia?? Rifampicin phenytoin methotrexate
619. Virus that cause Warts? papilloma virus

620. Which of these drugs cause nephrotoxicity with aminoglycosides?

Diuretics

621. Case: man has leg ulcer and hyperglycaemia what is the disease that increase
the ulcer:
a. Hypertension b. glaucoma c. nephropathy d. neuropathy
622. ptn came to pharmacy with old prescription, he wants to repeat the
antibiotics, ur boss told u ok coz he knows him, what should u do?
refuse to dispense it and report HAAD

623. arrange the following descending from higher acidity to lower

a. aqua regia (acidic).b. sulfuric acid (acidic)c. dist. Water (neutral)d. Na.
bicarb (alkaline)

624. arrange the following from less to more important?

Case report,Case study,Case control,cohort study

625. - drugs used in ttt of non-Hodgkin and RA:

a. Rituximab b. Omalizumab(Asthma) c. Adalimumab (only in RA)

626. How can u measure morphine solution: Oral syringe

627. Drugs can be returned for this reason except???

a. Factory not follows GMP b. AI partially degraded
c. excipients partially degraded d. no of tablets not written in the bottle

628. what is true about clearance?

Cl = elimination rate/cons. cl = Q*ECl= 0.7 (Vd/t1/2)

629. Which of the following is an example of oligosaccharide?

a. Sucrosedi b. Starch poly c. Glucose mono

630. Amino acid IV solution may contain all the following:

a. Low amount of non-essential amino acids.
b. Different concentrations of different amino acids.
c. Contain amounts of big branched amino acids.
631. A patient come to your pharmacy and give you a prescription, you told
him to come two hours later. When he comes, his prescription was not ready.
he shouted at you. what would you say to him:
a. Calm down his behaviour disturbs all in the pharmacy
b. If you continue to shout your prescription would take a longer time.
c- Go out and get your medicine from another pharmacy.
d- Shout at him and tell him to go out.

632. What are the major causes of hypercalcemia?

a- Malignancy, calcium dietary.
b- Malignancy, hyperparathyroidism.
c- Calcium dietary, hyperthyroidism.
d- Malignancy, hyperthyroidism.
633. A patient comes to your pharmacy and behaves in a rude manner. How
would you deal with him?
a- Assertiveness. b. Aggressiveness. c. Frustration d. Rudely.

634. A patient was prescribed for hypercalcemia. What is the serum calcium
concentration above which the patient is to be considered as hypercalcaemic?
a. 10.5 b. 8.5 c. 15.5 d. 9.5

Note: Normal range is (8.5-10.2)

635. A prescription came to you with atenolol. But you give the patient
allopurinol instead of atenolol. What would you do first?

a. call the patient b. call the physician c. Call the Haad.

636. Methotrexate is used in:

a. psoriasis b. breast cancer c. osteoporosis

637. Treatment of alopecia include:

a. finasteride b. minoxidil c. chlorhexidine

638. Drugs cause dry mouth:

a. simvastatin b. hyoscine butyl bromide

639. Which one of the following is a vaccine:
a. Tamiflu b. engerix-b c. tripedia

640. Omega 3 tablets dose in a patient with myocardial infarction would be?
1gm

641. Study of the effect of diabetes mellitus on pancreatitis using historical

insurance claim is called?
Case Control studies

642. which of the following Antiseptic and germicide:

a. Povidone b. Chlorhexidine c. Cetyl Pyridinium

643. . control study:

means comparing variable between 2 groups one takes drug and one placebo

644. All of the following are methods for emulsions stability test EXCEPT:
a. Viscosity b. Flocculation c. coalescence d. miscellization

645. suppository basis EXCEPT:

a. cocoa butter b. Gelatin

c. Polyethylene Glycol d. Ascorbyl Palmitate

646. the term (drug misuse) means:

a. Taking more than giving dose b. Taking less than giving dose
c. Taking other people medication d. All of the above

647. which of following used in kidney disorder because it has

nephroprotective property:
a. Cisplatin b. azathioprine c. dopamine

648. If you search for drug formulation reference,properties,structure

andpurity substance, drug formula reference:

a. pharmacopeia b. Martindale c. Remington

649. The errors that occur in pharmacy?

a. report haad b. discuss with patient c. reported in file in pharmacy

650. In 24 hours pharmacy we need:
3 Pharmacists and unlimited number of assistants

651. High volume of distribution meaning?

high tendency to bind to tissues

652. a prescription of verapamil with not clear handwriting what to do?

Call the doctor and ask him

653. Act as adsorbent:

a. Charcoal b. Kaolin

654. organ responsible for lipid+protein+TG synthesis: Liver

655. IV ROUTE IN EMERGENCY

656. which is not true about immune reconstitution inflammatory syndrome :

A-Corticosteroids and anti- inflammatory drugs don’t shorten inflammation action
b-The action of antiviral start when virus load is high
c-The pt start respond to treatment when CD4 is high or something like

657. Patient was on cyclosporine and changes to tacrolimus. Tacrolimus

comparison with Cyclosporine all answers are true except:
a. more potent
b. less nephrotoxicity
c. longer duration

tacrolimus more potent than cycosporine and cause more hyperglycemia,

hyperlipidemia and nephrotoxicity as compared to cyclosporine (gum
hyperplasia and hirsutism)

658. Cyclosporine is more toxic in which route?

a. IV b. SC c. oral

659. Emulsions undergoing different temperatures by increasing the temperature so

what the effect will happen to it
a. oiling
b. Molting
c. Caking
d. cracking

660. the most common side effect of (furosemide, corticosteroids, tetracycline) is:
a- acute pancreatitis
b- Acute gout
c- Megaloblastic anemia
d- Acute asthma

661. In Randomization controlled trials, randomization refers to:

Randomly assigning people to groups that compare different
treatments(True)
N.B) The other choices is about taking definite people not random

662. Bioavailability of the drug decrease

a-decrease renal clearance.
B-increase the oral dose
c- Highly bound to protein binding

663. Case about a patient having GERD … the purpose of the question what
secrete gastric acid
A-Histamin
B-Parietal cells

664 .physiological mediator for acid secretion in stomach:

A.Gastrin
B.histamin
C.Muscurinic
D.vagal response

665. If drug is taken by incorrect route, what will happen?

a. Ineffective
b. Toxicity
c. Drug interaction
d. Omission of doses
666. pt. has pain in his left eye and he sees halo around light
A. Glaucoma ✔
B.cataract
Note: Cataract: blurred vision
Glaucoma :pain

667. Female is menopause, she experiences hot flushes, developed spinal

osteoporosis which to use?
a. Aldosterone
b. Estrogen and progesterone

668. electrical conductivity of emulsion, dispered phase is:

a-Aqueous
b-Non-aqueous

669. patient need to refill prescription but the dose is not appears clearly what u should do?
Call the doctor and ask him about the dose

670. A drug with t1/2 3hrs ,how many of this drug will remain in the body after 24
hrs ?

less than 1%

671. otic is a word used for which part of body :

a. Ear
b. Eye

672. if a patient has a disease in his eye he should be referred to a :

a. Pathologist
b. Opthalmologist

673. The most poisoning of children happens in :

a. Home
b. Playground
c. School
674. The most important poisoning treatment measure is :
a. Prevention
b. Supportive
c. Treatment

d. supervision

675. A pharmacist in a busy pharmacy is making counseling session with a patient

what he should do :
a. Ending the session early
b. Asking the staff to be quit to concentrate with the patient

676. Hard gelatin capsule is not suitable for filling material :

a. Capsule
b. Paste
c. Liquid
d. Table

677. - regardingpoisining which can be used :

a. Charcoal
b. Kaoline
c. Both
d. None of the above

678. Formula for calculating the dose for a child more than 2 years :
young's rule = age/age+12 × ADULTS DOSE

679. Who is responsible for filling instruction for a prescription

a. Nurse
b. Prescriber
c. Pharmacist

680. the definition of hematinic:

drug or a medicine or a vitamin that increases the hemoglobin content of the blood.

A hematinic is a medicine that increases the hemoglobin content of the blood.

Hematinic are used to treat iron-deficiency anemia. Hematinic are usually
vitamins or minerals, such as vitamin B12 or iron, that are essential for
normal erythropoiesis.

681. The aim of adding sugar is : sweetening agent

682. which drug used in pregnancy with hsv:( herpes simplex virus)

Acyclovir (drug of choice)

NOTE: also valacyclovir, famcyclovir are used

683. If woman pregnant with HIV use

zidovudine or lamivudine

684. Most common cause of frequent urination,low flow rate of urine,and UTI :
BPH

685. which of the following is true about ORILSTAT ?

a. it inhibit absorption of dietary fat (Lipase inhibitor)1st

b. patient should consume about 30 % of fats in diet (not more than 30% fats in
daily total calorie) 2nd

c. no more than one dose should be taken in 24 hours

686. immune serum globulin is usually administrated by which type of injection ?

a. intradermal b. im c. iv

d. sc e. anyone of them

687. For dosage that may develop confusion for the route of administration ; as
pharmacist as if what of the following you will do or act
A. Remove label and cancel it
B. Write the expiry date on the label
C. Write the right method of administration on the label
D. Return the whole prescription to the Dr

688. as if is a pharmacist make counseling , why

a. To monitor therapy out come b. Reduce side effect

c. Improve compliance d. All

689. Aerosol is a colloid of fine solid particles or liquid droplets, in

Gas

690. What occur as a result of hypoventilation

Hypoxia,, Cystic fibrosis

691. adjusting ph &buffering of ophthalamic preparation to:

a. To be more comfortable b. To improve solubility
c. To improve bioavilability d. ALL

692. NB. if water is internal phase so classified W/O and if water is the
external phase then O/W
693. Advantage of IV route is true: (without except)
a.used in emergency
b.dose can be titrated
c.fastest
d. safe and convenient

694. what would be the rate of infusion of calcium in case of hypocalcaemia?

a- 400-500ml/hr.
b- 500-100ml/hr.
c- 200-300ml/hr.
d- 1000-1500ml/hr
695. If a female with vaginal infection came to you. You would refer her to
physician if she
a- Older than 60 years old
b- Has repeated infection
c- Went to physician previously for the same reason

696. The person with ultimate responsibility of wrong dispensing of drug is

Licensed pharmacist
697. To get primary drug information
a- primary literature
b- Scientific journals

698. Tylenol Elixir (Acetaminophen 160mg + 8mg codiene) example of:

a. pharmacist intervention needed
b. requires a written order from an authorized prescriber
c. example of legally exempted codeine product
d. regulated under the Benzodiazepines and Other Targeted Substances Act

699. All of the following are reasons that elderly patients are more susceptible to
drug-induced
cognitive changes, EXCEPT:
a. elderly patients are more likely to take multiple drugs.

b. elderly patients may have hepatic dysfunction.

c. elderly patients may have renal dysfunction.

d. elderly patients are more sensitive to CNS effects of drugs.

e. elderly patients have increased metabolic rates for producing psychoactive
metabolites.

700. All of the following are cytochrome enzyme EXCEPT:

a. CYP 450 b. CYP 3A4 c. CYP 0
d. CYP 1A4 e. CYP 2A1

701. Intrinsic gastric factor:

a. Iron b. Folic acid c. Cyanocobalamine

702. MOAI given with nasal decongestant can cause?

HTN crisis

703. where histamin is stored in the GIT

A-Basophiles
B-Parietal cells

704. Patient was on cyclosporine and changes to tacrolimus) Tacrolimus

comparison with Cyclosporine, what’s true about tacrolimus?
a) longer duration, less nephrotoxic, need low dose of corticosteroid along with it.
b) lower rejection rates, less potent, less nephrotoxic
c) short duration, less nephrotoxic, need low dose of corticosteroid along with it.
d) lower rejection rates and it need low dose of corticosteroid along with it.

705. Lithium CI with? Ibuprofen

706. Cyclopegia- paralysis of the ciliary muscle of the eye resulting in a loss of
accommodation

707. Immune serum globulin is usually administrated by which type of injection?

a.IV b. IM c. SC d. intradermal e. all

708. Which of the following must adjust the dose in renal impairment:
Digoxin - pyrazinamide

709. Beta blockers are used in all the following except:

a) Migraine
b) Bronchial asthma
c) Hyperthyroidism

710. Corns are associated with:

High pressure from shoes

711. A case 54 yrs pt. feels fatigue even while doing daily physical activity such
as brushing, taking bath . feels shortness of breath with little movement , needs to
keep at least 2 pillows to sleep with comfort . According to New York Heart
Association (NYHA) classification , he belongs to?
Class 4
712. Aim and Objectives belongs to which part of research paper ?
a. Introduction
b. Discussion
c. Methodology
d. Conclusion

713. A pt. complaints of darks stool, constipation. which medication is she likely
into?
Iron supplement

714. Use of VEEGUM in topical prep. such as creams and ointment ?

a. Colouring agent
b. emulsifying agent
c. suspending agent
d. Preservative

715. Special method used to prepare emulsion ?

a. Dry gum method
b. dry heat

716. A long case summary of pharmacokinetics – First order kinetics depends on?
elimination half-life

717. Process of adding carbohydrate to protein is called as? Glycosylation

718. A long case summary - How to assess medication adherence in pt.?

a. Check physician visit record
b. Check prescription refill
c. Ask pt.
d. Ask Pt.’s wife

719. A 65 yrs man had past history of surgery 3 yrs ago , c/o heart burn, abdominal
discomfort while eating , pain in stomach after eating . He has two wives , Drinks
4-5 cups of coffee , smokes 20 cigarettes/day , takes NSAIDs for pain . how many
risk factors are contributing to peptic ulcer disease ?
a. 1
b. 3
c. 4
d. 6
Be careful, if the case says it female pt. and above 70yrs then these are also the
risk factors of PUD
720. A long case with lots of lab test . only WBC is high . what is the indication?
Infection

721. Which of the following is correct for water of injection?

a. comes as multiple use vials
b. contains less than 1000/L microbes
c. prepared through reverse osmosis
d. It is packed as 2L

722. How many phases are required in clinical phase to approve new drug?
3 phases

723. Herb that works like ondansetron ?

Ginger

724. A long case summary. pt has egg allergy and wants to take vaccine. which
vaccine is CI?
MMR

725. A case of female athlete feels dizzy, weakness,fatigue and not able to do her
daily practice for her upcoming competition . She had heavy menstruation last
year. what is the intervention ?
a. Give her iron supplements extended release for whole day
b. Give iron supplements with ascorbic acid
c. take iron supplements along with a cup of tea or coffee

726. What is the meaning of Attunated vaccine ?

pathogen with less virulence and still viable

727. what difficulty does KSA faces during pilgrimage season regarding safety?
Controlling the epidemic disease

728. which drug formulary will u refer to find the drug-drug interaction of two
drugs ?
Lexicomp
729. Structure of phospholipids is given as asked which statement is right?
Hydrophilic head with hydrophobic tail

730. A case of pt. who had anaphylactic reaction of red rashes after administering
vaccine?
a. Type I
b. Type II
c. Type III
d. Type IV

731. Pharmacist gave a tight hand shake to manager before leaving the pharmacy.
What kind of communication is this?
a. Verbal
b. Non verbal
c. Physical
d. Visual

732. A female customer comes to pharmacy and doesn’t know how to administer
vaginal pessary. The pharmacist shows her sires of images to administer the
medication . what kind of communication is this type?
a. Verbal
b. Non verbal
c. Physical
d. Visual

734. Manager of an institute sets aim and goals for the company . this falls under
which category of principles of management ?
a. planning
b. directing
c. organising
d. controlling

735. A pharmacist dispensed a wrong drug and ultimately caused a drug error . it
was notified to manager. what will the manager do?
a. fire the pharmacist
b. conducts a meeting, discuss abt the error openly and find ways to overcome
c. Shouts at the pharmacist infrnt of the pt.
d. complaints to MOH

736. A case given and the pt is taking sevelamer for. what is its side effect?
Hypocalcemia
737. In phase I of clinical trails , which statement is true:
A drugs metabolism and excretion are studied on healthy individual

738. Which statement is correct in Lipinski rule of 5 ?

739. gene variant ?

a. genotype
b. phenotype
c. allele
d. haplotype

740. A structure that has both sugar and non-sugar end ?

Glycoside

741. whn should woman start folic acid before pregnant ?

1 month before

742. when a pharmacist doesn’t disclose the pt. name or medical condition of that
pt. in public is known as? confidentiality

743. what is the use of water for injection?

preparation of parenteral drugs

744. Humanistic outcome is measured by?

quality of life

745. Toxicity of carbon monoxide due to?

decrease oxygen carring capacity of hemoglobin
746. First line of sepsis? Norepinephrine

747. Frist approach to diaper inflammation? Petrolatum

748. measure crcl in a case? Equation of creatinine clearance in adult? Cockcroft-

Gault

749. Most source of infection in sterile area is? People

750. Carbohydrate polymer ? Glucagon

751. scale for adverse drug reaction with drugs ? Narnjo scale

752. Oleaginous base for ointment? white petroleum

753. To estimate Cr.cl in pediatrics we use? Equation of creatinine clearance in

children?
Schwartz equation

754. Normal plasma in human body in liter ? 3.5 L

755. function of coenzyme Q ? Reduce NAD to NADH

756. in buffer room type of gloves ? sterile gloves with powder

757. Naranjo scale for drug = 9 what does that mean ? Definite

758. What is function of golgi bodies? Energy production

759. if the mean age of participant is 50 with 5 standard deviation meaning ?

Within 5 of the age

760. Which association that define Thalidomide disaster ? kefauver-harris

amendment

761. Which one carry high risk for IV admixture?

Preparing IV admixture from non-sterile products

762. Central tendency affected by skewing values which one? Range

763. Isotonic NS and Dextrose solution? 0.9 % saline
Or 5% Dextrose

764. which of these measures used in central tendency?

Measures of Central Tendency: Mean, Median, and Mode

765. What is the best method to present Numerical data ? In tables

766. Concentration menthol in 0.6 syrup ? 6

767. causality assessment scale? Naranjo Algorithm

768. What is benefit of OTC ? Easely accessible for patients

769. Iso 5 particle size?

no more than 3,520 par3cles equal to or larger than 0.5 microns per cubic meter of
air

770. Aspirin bond ? Covalent

771. Role of Krebs cycle? Energy production (production ofATP)and biosynthesis

772. Most group use OTC? Adult

773. If a drug has Mwt more than 500 in which way will excrete? Biliary

774. Volume of blood in the body? 5 liters

775. Normal range of Cr. Clearance?

Normal creatinine clearance is 88–128 mL/min for healthy women and 97–137
mL/min for
healthy men
or
Creatinine clearance in a healthy young person is about 95 milliliters per minute
for
women/120 milliliters per minute for men. This means that each minute, that
person's
kidneys clear 95-120 mL of blood free of creatinine

776. Resting membrane potential ion distribution?

2Na and 3k inside while 3Na and 2k outside the inside is negative and the outside
positive
the resting membrane potential is -70

777. Enzyme metabolize starch? Amylase

778. Sevelamer phosphate binder?

Sevelamer, a polymeric compound, acts by binding to phosphate molecules in the
gut,
limiting its absorption and thus lowering serum phosphate levels w/o altering Ca,
Al, or
bicarbonate levels

779. Abbreviation lead to drug error

780. In which place produces spinal fluid? choroid plexus

781. Boric acid in preparation? buffer

782. Buffer system in human body? Bicarbonate

783. Meaning of OMM abbreviation?

Optimal Medical Management medicine

784. In parenteral nutrition what take in consideration when calculating?

Propofol

785. How we measuring Synthetic liver function?

Albumin

786. Example of 2 different drugs, similar letters, How we avoid errors when we
inter the
prescription to the system? tall man letter

787. not from WBC ? reticulocyte

788. The organ is responsible for energy production in the body? Liver

789. Cockcroft-Gault used to calculate ? Stable chronic renal impaired

790. Intangible cost? Pain, suffering, anxiety and fatigue

791. pc= after meals

792. Reabsorption of Amino acid in renal tubules? proximal convoluted

793. Colon absorptive surface is important for? water, K

794. Precursor of bile? Cholesterol

795. Function of GOLGI bodies in the cell?

transporting, modifying, and packaging proteins and lipids into vesicles for
delivery to targeted destinations

796. Function of mitochondria in the cell? Energy

797. PRN = as needed

798. Naranjo score is 3 for propability so it is? Possible

Note: Naranjo score is from -4 to +13

1 to 4 possible
5 to 8 propable
9 and more definite
0 and less doubtful

799. Define maslow needs in order

800. Which type of medication that can be crushed? Immediate release tablet

801. sidanafil and tamsulosin?

24 h separation of doses

802. sidanafil and tadanafil ?

4h separation of doses

803. tamsulisin and tadanafil?

48h separation of doses

804. What are the vaccines that are kept in the freezer?
Varicella zoster, MMR

805. A child has muscle pain and the doctor examined the thickness of his skin,
what are the options?
a. To know the amount of fats.
b. To examine the artery, think.
c. To know the thickness of its skin

806. What is the enzyme that converts folate(vit b9)?

Methylenetetrahydrofolate

807. How is the form of vitamin D in the kidneys?

D3, 1,25-dihydroxycholecalciferol is produced by the kidney

808. Niacin side effect ?

flushing and dyspepsia

809. Function of chylomicron ? (Adipose tissue)

A-transport fat from intestine to tissue
B-transport lipid from intestine to tissue
C-transport lipid from liver

810. What is the purine base of nucleic acid?

A-adenine and guanine
B-cytosine and thymine(pyrimidine bases of DNA)
C-cytosine and uracil(pyrimidine bases of RNA)

811. 1 gtt ou TID meaning ?

One drop in both eye three times

812. contraindication of enteral feeding?

Major GI bleeding, high output uncontrolled fistula ,paralytic
lieus , intestinal obstruction, Generalized peritonitis

813. Facultative Halophile organism mean?

That survive and reproduce at high salt concentration, but also
can survive and reproduce at not high salt concentration .

814. Which Immunosuppressive Agent cause Hirsutism

A- cyclosporin B- azathioprine C-sirolimus

815. Active form of Vitamin D ?

calcitriol

816. Which osteoporosis drug reduce risk of hip fracture?

Aledronate

817. Dose of Ca in 76y/o male with osteoporosis ?

1200mg/D

818. Why ibuprofen increase bleeding of warfarin ?

Moi ( warfarin & NSAID )
High protein binding and the cytochrome P450 (CYP)-dependent
clearance mechanisms of NSAIDs can affect the serum levels of warfarin

819. Cost effectiveness

different clinical outcomes

820. Cost utility

quality of life

821. Cost benefit

estimating the strengths and weaknesses of alternatives used
to determine options which provide the best approach to *achieving
benefits while preserving savings

822. Test dragendorff

Alkaloid

823. Palmetto Saw plant for

BPH
824. Drug causes acute renal function ?
Aminoglycoside,ACEIs, NSAIDs

825. Structure BDZ

826. Structure lbuprofen

827. Structure aspirin

828. Structure dihydropyridine

829. Fast route administration

IV and then rectal

830. woman she can't sleep, Your advice to her

A. Eat food before go to sleep
B. Drink water before go to the bed
C . Reduce exercises
D. Wake up and sleep same time

831. advers effect drug

SFDA

832. Which set the rules and regulations for pharmacy practice in Saudi Arabia?
MOH

833.Antidote snake bites

antivenom add neostigmine if there is tachycardia

834. lab test low phosphate

vitamin D

835. Case scenario 2 patient isolated for new disease ?

Case-series

836. certified pharmacist?

SCFHS

837. ISO5 class?

100

838. vaccine for Hajj ?

Hep A , Hep B ,IPV , MCV,MPSV ,TD

839. vaccine live- attenuated?

MMR, RV, Varicella, Zoster

840. your cousin come to your pharmacy ?

Justice queue in a row

841. calcium in pregnant?

1200-1500

842. clopedgrel
cyp19
843. warfarin
cyp9

844. MTX+corticosteroids =
Give adalimumab

845. MTX as mono therapy =

give infliximab

846. Elevated liver function due vitamin A or B3 ?

vitamin A

847. Despenia➡ ticagrelor

848.Dyspepsia➡ Dabigatran

849. Incidence
measures the risk that a new disease develops in each
population within a specified period, Incidence (%) * 100

850. prevalence
measures the extent to which a certain disease (i.e., new or
pre-existing) is spread among a given population within a specified
period

851. Relative risk (RR)

is mainly used in cohort studies, while odds ratio is mainly used
in case-control studies

852. Cost minimization analysis (CMA):

Finds the least expensive drug and assumes that the two
alternatives have equal efficacy

853. Cost utility analysis (CUA):

Measures therapeutic consequences inutility units and the
outcomes is calculated by quality-adjusted life years (QALYs)

854. Iron function

(specifically hemoglobin) transports oxygen in the blood
855. Treatment of hyperkalemia
calcium gluconate
calcium chloride
insulin , bicarbonate , diuretics , hemodialysis

856. hepatic encephalopathy how decreases ammonia

Lactulose

857. plant decreases or prevent UTI

cranberry juice

858. 797
sterile preparations

859. Immunology . What is hapten?

Hapten : small molecule never induce immune response unless
coupled with carrier protein.

860. Which immunoglobulin can pass placenta?

IgG

861. immunoglobulin in human colostrum?

IgA, IgM

862. The biological agents temperature?

2 to 8 °C

863. Varicella vaccine for

Chickenpox

864. How to avoid STDs? ( sexually transmitted disease)

Using condom

865. Source funding for service delivery ?

MOH

866.Which type of bacteria can growth equally in presence or absence

of oxygen:
Aerotolerant anaerobe
867. Pili function in bacteria ?
Pili are used to transfer DNA and for attachment to surfaces.
Pili are used for motility

868. Endotoxin characteristic ?

Endotoxins are heat stable lipopolysaccharide-protein complexes which form
structural components of cell wall of Gram Negative Bacteria and liberated only on
cell lysis or death of bacteria.

867. Polysterene role ?

a. Increase Ca
b. Increase k
c. Decrease Ca
d. Decrease k

868. Intern pharmacist want to search in letirature where she should

search ?
pub med

869. Ebola transmission

Body fluids

870. Ebola effect ?

Hemorrhagic fever

871. Function of colipase ?

Colipase is a cofactor of pancreatic lipase. It allows the lipase
to anchor itself to the lipid-water interface. Without colipase the enzyme is washed
off by bile salts, which have an inhibitory effect on the lipase. Enterostatin has a
biological activity as a satiety signal.

872. Patient with hypotension and WBC was over 10000 what should
patient receive ?
ringer lactate

873. Drug cause tachycardia when infused rapidly ?

amitriptyline
Theophylline
874. Which of the following reduce severity and duration of cold ?
vitamin c

875. Which of the following capsule size has the largest size ?
000

876. What can we use for sterilization of gloves ?

isopropyl 70%

877. can use tap water for compounding

external preparation

878. Which drug cause crystalluria

sulphadiazine, acyclovir, triamterene, piridoxylate, primidone

879. Type of allergy from bennett butter?

Type IgE

880. Ig for allergy?

Type IgE

881. Which immunoglobulin found in serum predominantly?

Immunoglobulin G (IgG)

882. First Ig released in the body?

IgM

883. Allergy types?

884. By which one antibodies are produced?
B lymphocytes

885. Passive immunity?

Immunoglobulin

886. Patient has eaten peanut and he develop angioedema and swelling so which
type of
allergy?
Immediate allergy

887. Which one is true about cromolyn for prevention of allergic rhinitis?
Take it before contact with allergen, 1 to 2 weeks prior to allergen

888. Allergic hypersensitive?

IgE

889. Which one of these in blood?

IgG

890. Which one of these have gamma globulin?

IgG

891. Type of immunoglobulin initiate when infection attack?

IgM

892. Which type of immunoglobulin that caused an Immediate immunity ?

immunoglobulin E (IgE)

893. Ig can’t reach to placenta?

IgM

894. Which of the following is the most likely to cause serious bleeding when are
given with aspirin?
A) Antacids
B) PPIs
C) H2-antagonists

895. Drug interactions between clopidogrel and omeprazole through which enzyme
?
Omeprazole —> enzyme inhibitor
Clopidogrel —> prodrug
Omeprazole inhibit conversion of clopidogrel to the active metabolite
So we have to shift to pantoprazole

896. The synthesis of glycogen from glucose called?

Glycogenesis

897. Creatinine Released from ? muscle

898. Creatine Released from ? liver

899. Health care system?
a. Primary
b. Secondary
c. Tertiary

900. Recall ? industrial error in number of batches

901. Withdrawals ?
stop the production due to death, confirmative serious, lethal effect
902. Suspended ?
for more investigation about the drug

903. If the Child less than 9 years of age He take flu season vaccines in first time?
Give Two Dose of flu season vaccine the durations between two dose in less 4
week

904. if Greater child than 9 years old or adult and he take vaccines in first time?
just take One dose

905. Administrators route of vaccine? All vaccine —> IM

906. except ?
IM or SC: 1- IPV* inactivated polio vaccine
2- PPSV pneumococcal polysaccharide vaccine
Orally: 1- OPV oral polio vaccine
2- RV Rotavirus vaccine
SC: 1- MMR
2- Varicella
3- Zostavax

907. All vaccine in refrigeration (2-8 C) Except ?

Zostavax in frozen “BELOW -15”

908. influenza (flu) vaccine with antiviral medications, Have two influenza
vaccine?
1- inactive influenza vaccine: I can take with antiviral drug no problem
2-Live attenuated vaccine: Cannot take together
- should stop antiviral 48 hours than take Live attenuated influenza vaccine
- take live attenuated influenza vaccine then wait 2 week after 2 week you can take
antiviral

909. Administration of vaccine?

1- All Live vaccine and inactivated vaccine: can take together
2- All inactivated vaccine: can take together but if missing one dose of inactivated
vaccine - you can take tomorrow
3- All live vaccine: can take together - but if missing one dose - you can take after
28 day
910. Corticosteroids with Live vaccine?
1- if the patient take high dose of steroids less than 14 day: you can give live
vaccine
2- if the patient take high dose of steroids more than 14 day: you cannot give the
vaccine should discontinuing the steroids 1 months at least than you can take the
vaccine
911. Hep B vaccine: Newborn , 2 months, 4 months, 6 months

912. Hep A vaccine:

a. 18 months
b. 24 months
c. recommended for travel to most part of the world

913. MMR vaccine: 12 months, 18 months, (4-6 years)

914. Pregnancy receives one Tdap dose any trimester of pregnancy ?

Third trimester

915. Deep wound + Unknown Vaccination history? Td + TIG

916. Deep wound + Patient has vaccinated within 5 years ? No vaccine

917. Deep wound + Patient has not vaccinated within 5 years ? Only Td

918. Minor wound + Unknown vaccination history ? only Td

919. Minor wound + Patient has vaccinated within 10 years ? No vaccine needed

920. Minor wound + Patient hasn’t vaccinated within 10 years ? only Td

921. Latex? HPV , RV

922. Gelatin? MMR , yellow fever ,Varciella, Zoster

923. Egg? MMR , yellow fever , influnza vaccine

924. Neomycin? IPV ( inactivated polio vaccine ), MMR , Varciella , zVL

925. if the drug have 5 hr half-life how many % of drug after 24 hr ? 3.13%
Hours: 0 – 5 – 10 – 15 – 20 – 24
Percentage: 100% - 50% - 25% - 12.5% - 6.25% - 3.13%

926. What Is The Most High Risk When Happen Error?

a. Look Like Medication
b. High Alert Medication
c. Sound Like Medication

927. Medication not to give in G6PD deficiency ?

Sulfa + Quinolone + Aspirin + Chloroquine + nitrofurantoin

928. You want to inform the population about something what is the best way to
inform them?
Media hub

929. Convince someone to take vaccine type of this ? logic (logos)

930. Persuasion has three basic types: Ethos – Logos – Pathos

1- Ethos: It is linked with morality and ethics.
2- Logos: Logos comes of logic, therefore writers use logic, reasoning, and
rationality to
convince audiences of their perspectives.
3- Pathos: The third method is pathos, which invokes and appeals to the emotions
of the audience.

931. Nonverbal communication? body position

Other examples:
eye contact, facial expressions, gestures, posture and body orientation, body
language, touch, para-linguistic, silence.

932. Prescription you can’t read properly what is written what do you do?
Call the physician to double check

933. 795
Non sterile preparation

934. Natural product for burn? Aloe

935. Which drug should be in refrigeration?

These include insulins, antibiotic liquids, injections, eye drops, vaccine
936. What is apoptosis ? programmed cell death

937. In cough what is the enzyme ? Bradykinin

938. One came to you in the pharmacy and told you she opened the eye drop 45
days ago what should she do?
Discard the medication ( expiry date 28 days after open)

939. mean arterial blood pressure level Is 70-80 MAP?

a. 50 b. 55 c. 60 d. 65 (correct answer 73.3)
NOTE: MAP=DP+1/3(SP-DP) OR MAP=((2(DP)+SP)/3)

940.