Scribd Logo
Upload

Welcome to Scribd!

  • Lecture 24, Human-Microbial Interactions - EN

    Uploaded by

    Nariopolus
    5 views18 pages
    This document summarizes a lecture on human-microbial interactions and the microflora of the human gastrointestinal tract, skin, oral cavity, and mucosal tissues. It discusses how mammals can be classified based on where fermentation occurs in their digestive tract, such as foregut fermenters like ruminants and hindgut fermenters like cecal animals. It also describes the microflora found in different parts of the human body and their roles, including providing digestion of macromolecules and secretion of acids and vitamins in the gastrointestinal tract. Finally, it briefly discusses opportunistic pathogens like Candida albicans and issues like human microbiome, obesity, and interactions between pathogens and the human

    Original Description:

    Original Title

    Lecture 24, Human-microbial interactions_EN

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    This document summarizes a lecture on human-microbial interactions and the microflora of the human gastrointestinal tract, skin, oral cavity, and mucosal tissues. It discusses how mammals can be classified based on where fermentation occurs in their digestive tract, such as foregut fermenters like ruminants and hindgut fermenters like cecal animals. It also describes the microflora found in different parts of the human body and their roles, including providing digestion of macromolecules and secretion of acids and vitamins in the gastrointestinal tract. Finally, it briefly discusses opportunistic pathogens like Candida albicans and issues like human microbiome, obesity, and interactions between pathogens and the human

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    5 views18 pages

    Lecture 24, Human-Microbial Interactions - EN

    Uploaded by

    Nariopolus
    This document summarizes a lecture on human-microbial interactions and the microflora of the human gastrointestinal tract, skin, oral cavity, and mucosal tissues. It discusses how mammals can be classified based on where fermentation occurs in their digestive tract, such as foregut fermenters like ruminants and hindgut fermenters like cecal animals. It also describes the microflora found in different parts of the human body and their roles, including providing digestion of macromolecules and secretion of acids and vitamins in the gastrointestinal tract. Finally, it briefly discusses opportunistic pathogens like Candida albicans and issues like human microbiome, obesity, and interactions between pathogens and the human

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 18

    Microbiology 2

    CU20627

    Lecture 24
    K.F. Wannee
    Human-microbial interactions Lecturer Life Sciences,
    Chemistry Department,
    HZ University of Applied
    Sciences
    Mammals as Microbial Habitats

    Normal Human-Microbial Interactions


    • (Beneficial) Microflora of the Skin, Oral Cavity,
    Gastrointestinal Tract, and Mucosal Tissues

    Human-Pathogen Interactions
    The Mammalian Gut

    • Herbivores, carnivores, and omnivores


    The Mammalian Gut of Herbivores
    Foregut fermenters Examples: Ruminants (photo 1), colobine monkeys,
    macropod marsupials, hoatzin (photo 2)

    1. 2.

    Foregut
    fermentation
    chamber

    Acidic stomach

    Small intestine
    Hindgut fermenters Examples: Cecal animals (photos 3 and 4), primates,
    some rodents, some reptiles

    3. 4.

    Cecum
    Hindgut
    Large fermentation
    intestine chambers
    (colon)
    Microflora of the Human Gastrointestinal Tract

    -Digestion of macromolecules
    -Secretion of acid
    (HCl) → sterilization -Continued digestion
    -Absorption of bile acids
    -Absorption of monosaccharides,
    amino acids, fatty acids, water and vitamin B12
    • Colonization of gut begins at birth
    • Human gut microorganisms and obesity?
    The Human Microbiome
    Microflora of the Skin
    Microflora of the Oral Cavity
    Microflora of Mucosal Tissues – Respiratory
    Tract
    Microflora of Mucosal Tissues – Urogenital
    Tract (1)
    Microflora of Mucosal Tissues – Urogenital tract
    (2)

    e.g. Lactobacillus acidophilus


    Human–Pathogen Interactions: The Basics

    Mucus Colonization
    Microbial
    cells

    Epithelial
    cell
    Human–Pathogen Interactions: The Basics
    Opportunistic pathogens
    Candida albicans (yeast-like Methicillin-resistant Staphylococcus
    fungus) aureus (MRSA)
    Homework assignments

    • Assignment 21
    • Deadline Sun Dec 17th

    • Study theory lecture 25

    • Pre-class assignment lecture 25


    • Deadline Sun Dec 17th

    You might also like