Pre-K Assessment: Pemphigus

Vulgaris
1. What is pemphigus vulgaris?
a. A blistering disease caused by bacteria
b. A disease that affects the immune system
c. A condition that affects the bones
d. A common cold

2. How are antibodies involved in pemphigus

vulgaris?
a. Antibodies help protect the body from the disease
b. Antibodies cause the formation of blisters
c. Antibodies prevent the formation of blisters
d. Antibodies have no effect on pemphigus vulgaris

3. What happens to the skin in pemphigus

vulgaris?
a. It becomes thicker and stronger
b. It loses adherence and forms blisters
c. It becomes itchy and red
d. It becomes darker in color

4. Who is more likely to be affected by pemphigus

vulgaris?
a. Men
b. Women
c. Children
d. Elderly people

5. Which ethnic groups are affected at a higher rate

by pemphigus vulgaris?
a. African Americans
b. Hispanic Americans
c. Mediterranean and Ashkenazi Jews
d. Native Americans

6. Which part of the body is almost always involved

in pemphigus vulgaris?
a. The eyes
b. The mouth
c. The hands
d. The feet

7. What is a common symptom of pemphigus

vulgaris in the mouth?
a. Intact bullae
b. Map-like erosions and ulcerations
c. Superficial itching
d. Swelling of the cheeks

8. What is a positive Nikolsky's sign?

a. A nonspecific feature of pemphigus vulgaris
b. A sign of a different skin condition
c. A reaction to certain foods
d. A sign of infection
9. How is pemphigus vulgaris diagnosed?
a. Through a blood test
b. Through a skin biopsy
c. Through a urine sample
d. Through a physical examination

10. What is the main treatment for pemphigus

vulgaris?
a. Surgery
b. Antibiotics
c. Steroids and immunomodulatory drugs
d. Radiation therapy

11. How are refractory cases of pemphigus vulgaris

controlled?
a. With home remedies
b. With physical therapy
c. With intravenous immunoglobulin therapy
d. With acupuncture

12. What is paraneoplastic pemphigus?

a. A variant of pemphigus vulgaris associated with underlying neoplasia
b. A contagious form of pemphigus vulgaris
c. A form of pemphigus vulgaris that affects the eyes
d. A condition caused by excessive sun exposure

13. What type of diseases are associated with

paraneoplastic pemphigus?
a. Cardiovascular diseases
b. Neurological diseases
c. Arthritis
d. Underlying neoplasia

14. How does paraneoplastic pemphigus differ from

pemphigus vulgaris?
a. Paraneoplastic pemphigus only affects the skin
b. Paraneoplastic pemphigus is caused by a bacterial infection
c. Paraneoplastic pemphigus is more common in children
d. Paraneoplastic pemphigus is associated with underlying neoplasia

15. What is the role of autoantibodies in

paraneoplastic pemphigus?
a. They protect the body from neoplasia
b. They target and destroy desmosomes and hemidesmosomes
c. They prevent the formation of blisters
d. They have no effect on paraneoplastic pemphigus

16. How is paraneoplastic pemphigus diagnosed?

a. Through a blood test
b. Through a skin biopsy
c. Through a urine sample
d. Through a physical examination

17. What is the recommended treatment for

paraneoplastic pemphigus?
a. Surgical removal of the underlying neoplasia
b. Antibiotics
c. Radiation therapy
d. Diagnosis and management of the underlying neoplasm
18. Can the mucocutaneous disease of
paraneoplastic pemphigus resolve?
a. Yes, with proper treatment of the underlying neoplasm
b. No, it is a lifelong condition
c. It depends on the severity of the disease
d. It resolves on its own without treatment

19. Which of the following neoplasms has been

associated with paraneoplastic pemphigus?
a. Breast cancer
b. Lung cancer
c. Prostate cancer
d. Colon cancer

20. Why is the diagnosis and management of the

underlying neoplasm essential in paraneoplastic
pemphigus?
a. It can prevent further spread of the neoplasm
b. It can cure paraneoplastic pemphigus
c. It is a necessary step before any treatment can be provided
d. It has no effect on the mucocutaneous disease

Answer Key (Always review AI generated answers for accuracy - Math is more likely to be
inaccurate):

1. b
2. b
3. b
4. b
5. c
6. b
7. b
8. a
9. b
10. c
11. c
12. a
13. d
14. d
15. b
16. b
17. d
18. a
19. b
20. a