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17th March 2024 – Dermatology

Dr. Nuwangika Marcellin - 10:30am – 12:30pm


Consultant Dermatologist
BH, Balapitiya

Dermatology MCQ for MD Medicine Selection Exam

1. T/F Regarding Pyoderma gangrenosum,


A) The initial lesion is often a pustule.
B) Type of neutrophilic dermatosis.
C) Associated with cocaine use.
D) Bullous variant is commonly associated with inflammatory bowel disease.
E) Wide surgical debridement is the treatment of choice.

2. T/F Regarding Psoriasis


A) Streptococcal illness is associated with guttate psoriasis.
B) Salmon patch is a recognized nail change.
C) Arthritis mutilans is the most common type of psoriatic arthritis.
D) Antimalarials exacerbates psoriasis.
E) Acitretin is a mode of treatment in pustular psoriasis.

3. Lichen Planus
A) Mucosal lesions are seen in 70 – 75% of patients with cutaneous disease.
B) Enalapril is associated with lichenoid drug eruptions.
C) Lichen planopilaris causes non scarring alopecia.
D) Onycholysis is a known nail abnormality.
E) Erosive LP has a risk of squamous cell carcinoma.

4. Seborrheic Dermatitis,
A) Is a common mild chronic eczema that typically affects areas with a high density
of sebaceous glands – scalp, face, central chest and ano‐genital areas.
B) Etiologic links with Malassezia (Pityrosporum) species have been identified.
C) Extensive and therapy‐resistant seborrheic dermatitis can be seen in HIV infection.
D) More commonly observed in patients with Parkinson disease and cerebrovascular
accidents.
E) Topical antifungals are the mainstay of therapy due to their safety at all ages.
5. T/F regarding Acne
A) Abrupt, monomorphous eruption of inflammatory papules and pustules is often
observed in drug induced acne.
B) Acné excoriée is associated with stress.

C) PAPA syndrome is an autoinflammatory disorder associated with severe nodulocystic


acne.
D) Acne fulminans is characterized by the febrile ulcerative necrotic acne lesions aloand
various systemic inflammatory signs and symptoms.
E) Isotretinoin is a mode of treatment in pregnancy.

6. T/F regarding Hidradenitis Suppurativa,


(i) It is a chronic condition characterized by recurrent “boils” and draining sinus tracts
with subsequent scarring.
(ii) Occurs on eccrine gland bearing sites
(iii) There is a familial form of hidradenitis suppurativa with autosomal recessive
inheritance.
(iv) Women are more frequently affected than men.
(v) Associated with Crohn disease.

7. T/F regarding Immunobullous disease,


A) Bullous pemphigoid is characterized by flaccid bullae.
B) Mucosal involvement is seen in 80% of pemphigus vulgaris patients.
C) Although over 90% of Dermatitis Herpetiformis patients have evidence of a gluten‐
sensitive enteropathy, only about 20% have intestinal symptoms of celiac disease.
D) Vancomycin is the most common cause of drug induced linear IgA bullous disease.
E) Rituximab is a mode of treatment in severe pemphigus vulgaris.

8. Urticaria and Angioedema


A) Chronic urticaria is defined as urticaria lasting for more than 6 weeks.
B) Chronic spontaneous urticaria has been associated with autoimmune disease.
C) Schnitzler’s syndrome is associated with monoclonal gammopathy.
D) Drug induced angioedema is associated with low C4 levels.
E) Urticarial vasculitis resembles urticaria clinically but lasts less than 24 hours.

9. T/F regarding Sweets syndrome


A) GM‐CSF is known to cause drug induced sweets syndrome.
B) Up to 20% of patients have internal malignancies.
C) Vesiculobullous variant is most frequently associated with myelogenous leukemia.
D) The cutaneous eruption of Sweet’s syndrome favors the lower extremities.
E) Ocular involvement and arthritis are less common systemic manifestations

10. T/F regarding cutaneous vasculitis


A) Rheumatoid Arthritis is a known cause.
B) Poly Arteritis Nodosa is associated with subcutaneous nodules.
C) Type 1 cryoglobulineamia causes small vessel vasculitis.
D) Churg Strauss Syndrome causes necrotizing vasculitis of small to medium‐sized vessels
with infiltrates of eosinophils.
A) Infective endocarditis causes aseptic vasculitis.

11. T/F regarding lupus erythematosus,


A) 50 % of patients with discoid lupus erythematosus will progress to SLE.
B) Lesions of Subacute cutaneous lupus erythematosus has an annular configuration or
psoriasiform appearance.
C) Patients with Rowell’s syndrome have cutaneous lesions resembling toxic epidermal
necrolysis or erythema multiforme major.
D) Lupus panniculitis occurs predominantly on the face, upper arms, upper trunk,
breasts, buttocks, and thighs.
E) More than 90 % of patients with neonatal LE have anti La antibodies.

12. Leprosy
A) Tuberculoid leprosy is associated with high cell mediated immune response.
B) Type 2 lepra reactions are due to type 3 hypersensitivity reactions to lepra bacilli.
C) Skin biopsy is essential in diagnosis.
D) Rifampicin daily dose is included in leprosy muti drug therapy.
E) Agranulocytosis is a side effect of Dapsone.

13. T/F regarding skin infections,


A) Bullous impetigo is caused by streptococci bacteria.
B) Exogenous exposure to mycobacterium tuberculosis produces primarily the
tuberculous chancre and TB verrucosa cutis.
C) Chromoblastomycosis is caused by actinomycetes.
D) Cutaneous Leishmaniasis typically presents as a painful plaque with a central ulcer.
E) Kerion is usually caused by animal dermatophytes.

14. Genetic disease and skin,


A) Prescence of Axillary freckling is a diagnostic criteria of neurofibromatosis type 1.
B) Facial angiofibromas are typically present at birth in tuberous sclerosis.
C) Darier disease has autosomal recessive transmission.
D) Xeroderma pigmentosum patients have increased risk of cutaneous cancers.
E) Chronic mucocutaneous candidiasis may be associated with autoimmune
endocrinopathies.
15. T/F regarding Alopecia
A) Alopecia areata is a B cell driven autoimmune disease.
B) DLE on the scalp causes cicatricial alopecia.
C) Telogen effluvium is the most common form of scarring type of hair loss in association
with systemic diseases.
D) Trichotillomania is often associated with psychological stress or a personality disorder.
E) Spironolactone is a mode of treatment in female pattern hair loss.

16. 60‐year‐old male with chronic kidney disease presented with dusky skin macules
involving 40 % of body surface area. Some lesions had central bullae. On further
examination he had conjunctival erythema, painful oral ulcers, and genital skin peeling.
He was treated with cephalexin 1 week back by his GP for his oral ulcers. 6 weeks ago,
he started taking alopurinol 100 mg daily given by his nephrologist as his uric acid level
was high. His liver profile showed total bilirubin‐ 185 µmol/l, direct bilirubin‐ 149, ALT‐
250 U/L, AST‐ 162. What is the diagnosis?
A) Cephalexin induced Drug Reaction with Eosinophilia with Systemic Symptoms
B) Allopurinol induced Drug Reaction with Eosinophilia with Systemic Symptoms
C) Allopurinol induced Steven Jhonson syndrome.
D) Cephalexin induced Toxic Epidermal Necrolysis.
E) Allopurinol induced Toxic Epidermal Necrolysis.

17. A 25‐year‐old male presented with fever, malaise, arthralgia, and examination revealed
psoriasiform scaly plaques on trunk, palms, and soles. He has elevated AST and ALT and
gives a history of sexual promiscuity with an unknown partner. What investigation do
you need to confirm the diagnosis?
A) Blood picture
B) HIV screening
C) Skin biopsy
D) TPPA/TPHA
E) ANA
18. A 70‐year‐old female with diabetic nephropathy presented with following painful skin
lesions on her buttocks and thighs for 3 days. Initially it started as purple colored
mottling.

What is your diagnosis?


A. Medium vessel vasculitis
B. Antiphospholipid syndrome
C. Calcinosis cutis
D. Warfarin induced skin necrosis.
E. Calciphylaxis

19. 24‐year‐old female presented with generalized fatigue and recently she noticed below
changes in her hands. She has a habit of using sanitizers frequently and GP has treated
her as contact dermatitis with topical steroids without much improvement. She also has
itchy scaly scalp and GP has given ketoconazole shampoo without much improvement.
Her eyelids were swollen from time to time and treated for allergies by her GP. What
investigation do you order to help in diagnosing her condition?
A) Patch testing.
B) Skin prick testing
C) Creatine phosphokinase
D) Skin biopsy
E) Liver profile

20. 52‐year‐old diabetes patient presented with following asymptomatic lesions on his
trunk. What is your diagnosis?

A) Diabetic bullae
B) Diabetic dermopathy
C) Tinea corporis
D) Granuloma annulare
E) Discoid eczema

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