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Anatomy And Physiology 9th Edition

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Chapter 07: Cell Growth and Development
Patton: Anatomy and Physiology, 9th Edition

MULTIPLE CHOICE

1. The pairing of bases of a strand of DNA is obligatory. If a strand of DNA were composed of
the base sequence of ATCG, what would be the obligatory sequence of its opposing base
pairs?
a. TAGC
b. CGAT
c. GCTA
d. ATCG
ANS: A DIF: Application REF: p. 121
TOP: Deoxyribonucleic Acid (DNA)

2. Which of the following is not true of RNA?


a. It is a single strand.
b. It contains uracil rather than thymine.
c. The obligatory base pairs are adenine and uracil, and guanine and cytosine.
d. It contains deoxyribose sugar.
ANS: D DIF: Synthesis REF: pp. 122, 123 TOP: Transcription

3. The correct order of the phases of mitosis is:


a. anaphase, telophase, metaphase, prophase.
b. prophase, metaphase, anaphase, telophase.
c. prophase, anaphase, metaphase, telophase.
d. anaphase, metaphase, prophase, telophase.
ANS: B DIF: Synthesis REF: p. 129 TOP: Mitosis

4. When the chromosomes align themselves across the equator of the spindle fibers, it is
characteristic of which phase of mitosis?
a. Prophase
b. Anaphase
c. Metaphase
d. Telophase
ANS: C DIF: Memorization REF: p. 130
TOP: Mitosis

5. During which stage of mitosis do the centrioles move to the opposite poles of the cell?
a. Prophase
b. Metaphase
c. Anaphase
d. Telophase
ANS: A DIF: Application REF: pp. 129-130 TOP: Mitosis

6. Extensive weight training causes the muscle cells to:


a. atrophy.
b. hypertrophy.
c. undergo hyperplasia.
d. undergo anaplasia.
ANS: B DIF: Application REF: p. 132
TOP: Changes in Cell Growth, Reproduction, and Survival

7. A DNA molecule is characterized by all of the following except:


a. double helix shape.
b. obligatory base pairing.
c. ribose sugar.
d. phosphate groups.
ANS: C DIF: Memorization REF: p. 121
TOP: Deoxyribonucleic Acid (DNA)

8. All of the following occur as a result of meiosis except:


a. chromosome number remains at 46.
b. primitive sex cells become mature gametes.
c. the cells become haploid.
d. meiosis occurs in two steps.
ANS: A DIF: Memorization REF: p. 131
TOP: Meiosis

9. A sequence of three bases forms a(n):


a. codon.
b. anticodon.
c. amino acid.
d. polypeptide bond.
ANS: A DIF: Memorization REF: pp. 121-122
TOP: Deoxyribonucleic Acid (DNA)

10. Transcription can be best described as the:


a. degradation of tRNA.
b. reading of mRNA codons by tRNA.
c. replication of DNA.
d. synthesis of mRNA.
ANS: D DIF: Application REF: p. 122 TOP: Transcription

11. Which of the following statements is true?


a. Amino acid chains form DNA.
b. The site of transcription is within the nucleus, whereas the site of translation is in
the cytoplasm.
c. Uracil is present in DNA in place of thymine.
d. None of the above is true.
ANS: B DIF: Memorization REF: pp. 122, 123
TOP: Deoxyribonucleic Acid (DNA)
12. An individual’s entire set of DNA can be referred to as a:
a. chromosome.
b. chromatid.
c. genome.
d. cytokinesis.
ANS: C DIF: Memorization REF: p. 126
TOP: DNA Replication

13. Twenty-three chromosomes per cell in humans is referred to as:


a. haploid.
b. diploid.
c. myoid.
d. dioid.
ANS: A DIF: Memorization REF: p. 131
TOP: Meiosis

14. Which of the following terms is synonymous with tumor?


a. Anaplasia
b. Hyperplasia
c. Neoplasm
d. Benign
ANS: C DIF: Application REF: p. 132
TOP: Changes in Cell Growth, Reproduction, and Survival

15. If a sequence of nitrogen bases in nucleic acid were A-U-C-G-A, which of the following
would be true about the nucleic acid?
a. It contains deoxyribose sugar.
b. It could be found only in the nucleus.
c. It contains ribose sugar.
d. Both A and B are true.
ANS: C DIF: Application REF: p. 122 TOP: Transcription

16. The G1 and G2 phases of cell growth are separated by:


a. anaphase.
b. the S phase.
c. telophase.
d. both A and C.
ANS: B DIF: Memorization REF: p. 127
TOP: DNA Replication

17. DNA replication occurs during:


a. prophase.
b. telophase.
c. metaphase.
d. none of the above.
ANS: D DIF: Memorization REF: p. 128
TOP: DNA Replication
18. If a species of animal had 16 pairs of chromosomes in its normal body cells, its gametes
would contain _____ chromosomes.
a. 16
b. 8
c. 32
d. None of the above is correct.
ANS: B DIF: Memorization REF: p. 131
TOP: Meiosis

19. In protein synthesis, some segments of the RNA transcript represent noncoding parts of the
DNA. These are called:
a. exons.
b. codons.
c. introns.
d. spliceosomes.
ANS: C DIF: Memorization REF: p. 123
TOP: Editing the Transcript

20. The membranous organelle in the cytoplasm that is able to replicate itself is the:
a. Golgi apparatus.
b. mitochondrion.
c. lysosome.
d. ribosome.
ANS: B DIF: Memorization REF: p. 127
TOP: Production of Cytoplasm

21. Which of the following is not a phase of mitosis?


a. Prophase
b. Metaphase
c. Anaphase
d. Interphase
ANS: D DIF: Memorization REF: p. 129
TOP: Mitosis

22. The end product of the process of transcription is a(n):


a. mRNA molecule.
b. tRNA molecule.
c. protein.
d. new DNA molecule.
ANS: A DIF: Application REF: p. 122 TOP: Transcription

23. The end product of the process of translation is a(n):


a. mRNA molecule.
b. tRNA molecule.
c. protein.
d. new DNA molecule.
ANS: C DIF: Application REF: p. 123 TOP: Translation

24. If the original DNA code was ACG, the mRNA that would be formed would be:
a. UCG.
b. AGC.
c. UGC.
d. Not enough information is given to answer the question.
ANS: C DIF: Application REF: p. 123 TOP: Translation

25. If the original DNA code was ACG, the tRNA that would transfer the correct amino acid
would have which sequence of nucleotides?
a. UCG
b. ACG
c. UGC
d. Not enough information is given to answer the question.
ANS: B DIF: Application REF: p. 123 TOP: Translation

26. Interphase does not include which of the following?


a. M phase
b. G1 phase
c. G2 phase
d. S phase
ANS: A DIF: Memorization REF: p. 127
TOP: Mitosis

27. In the DNA molecule, obligatory base pairing always pairs:


a. A-G.
b. C-T.
c. A-T.
d. both A and B.
ANS: C DIF: Memorization REF: p. 128
TOP: Deoxyribonucleic Acid (DNA)

28. In humans, one gene consists of about how many nucleotide pairs?
a. 10,000
b. 1000
c. 100
d. 50
ANS: B DIF: Memorization REF: p. 131
TOP: Deoxyribonucleic Acid (DNA)

29. Which is capable of properly refolding an improperly refolded protein molecule?


a. Proteasome
b. Proteome
c. Chaperone
d. Polyribosome
ANS: C DIF: Memorization REF: p. 126
TOP: Translation

30. Which is capable of destroying improperly folded proteins that could possibly harm the cell?
a. Proteasome
b. Proteome
c. Chaperone
d. Polyribosome
ANS: A DIF: Memorization REF: p. 126
TOP: Translation

31. Which is the complete set of proteins that can be produced by the cell?
a. Proteasome
b. Proteome
c. Chaperone
d. Polyribosome
ANS: B DIF: Memorization REF: p. 126
TOP: Translation

32. The structure that holds two newly replicated DNA strands together is the:
a. centromere.
b. telomere.
c. spindle.
d. chromatid.
ANS: A DIF: Memorization REF: p. 128
TOP: DNA Replication

TRUE/FALSE

1. The terms cytokinesis and mitosis mean the same thing.

ANS: F DIF: Memorization REF: p. 129


TOP: Cell Reproduction

2. A nucleotide of a DNA molecule consists of a ribose sugar, phosphoric acid, and a


nitrogenous base.

ANS: F DIF: Memorization REF: p. 128


TOP: Deoxyribonucleic Acid (DNA)

3. The action of a gene is determined by the arrangement of the obligatory base pairs in the
nucleotides composing a DNA molecule.

ANS: T DIF: Memorization REF: p. 128


TOP: Deoxyribonucleic Acid (DNA)

4. A major function of DNA is to instruct the ribosome, through tRNA, concerning which
protein is to be synthesized.

ANS: F DIF: Memorization REF: p. 123


TOP: Translation

5. Protein synthesis begins with translation.

ANS: F DIF: Memorization REF: p. 122


TOP: Transcription

6. The enzyme DNA polymerase coordinates the mechanism of obligatory base pairing.

ANS: T DIF: Memorization REF: p. 128


TOP: DNA Replication

7. In normal mitosis, the two daughter cells are identical genetically to the parent cell.

ANS: T DIF: Memorization REF: p. 129


TOP: Cell Reproduction

8. Anaplasia is a state in which cells fail to differentiate into specialized cell types.

ANS: T DIF: Memorization REF: p. 132


TOP: Changes in Cell Growth, Reproduction, and Survival

9. Genes determine polypeptide structure, which determines the structure of enzymes and
structural proteins, which determine the cell’s functions and structure.

ANS: T DIF: Application REF: p. 121


TOP: Deoxyribonucleic Acid (DNA)

10. Chromosomes align across the equator of the spindle fibers during anaphase of mitosis.

ANS: F DIF: Memorization REF: p. 129


TOP: Major Events in Mitosis

11. One significant similarity between RNA and DNA is that they both are shaped as a
polypeptide chain.

ANS: F DIF: Application REF: p. 122


TOP: Deoxyribonucleic Acid (DNA)

12. Gamete is the result of a somatic cell undergoing mitosis.

ANS: F DIF: Memorization REF: p. 131


TOP: Meiosis

13. Normal meiosis results in daughter cells that are genetically identical to the parent cell.

ANS: F DIF: Memorization REF: p. 131


TOP: Meiosis

14. It is during meiosis phase I that the number of chromosomes is halved.

ANS: T DIF: Application REF: p. 131 TOP: Meiosis


15. Diabetes mellitus is a disorder of DNA replication.

ANS: F DIF: Memorization REF: p. 133


TOP: Mechanisms of Disease

16. Hypertrophy refers to an increase in cell size, whereas hyperplasia refers to an increase in cell
number.

ANS: T DIF: Memorization REF: p. 132


TOP: Changes in Cell Growth, Reproduction, and Survival

17. In transcription, the DNA of the cell is edited and the introns are removed.

ANS: F DIF: Memorization REF: p. 123


TOP: Editing the Transcript

18. The anticodon on a tRNA molecule has exactly the same nucleotide sequence as the DNA
code that formed that part of the mRNA molecule.

ANS: F DIF: Memorization REF: pp. 123-124


TOP: Translation

19. The anticodon on the tRNA molecule has exactly the same nucleotide sequence as the DNA
code that formed that part of the mRNA molecule except that uracil would replace thymine.

ANS: T DIF: Memorization REF: pp. 122, 123


TOP: Transcription, Translation

20. The mitochondria are unique organelles because they are able to replicate themselves.

ANS: T DIF: Memorization REF: p. 127


TOP: Production of Cytoplasm

21. The number of cyclin-dependent kinase enzymes varies greatly during the life of a cell.

ANS: F DIF: Memorization REF: p. 131


TOP: Regulating the Cell Life Cycle

22. Introns carry the code for the making of a protein.

ANS: F DIF: Memorization REF: p. 123


TOP: Editing the Transcript

23. A type of ribonucleic acid that can stimulate translation is called RNAi.

ANS: F DIF: Memorization REF: pp. 123-124


TOP: Translation

24. DNA synthesis occurs during prophase in mitosis.

ANS: F DIF: Memorization REF: p. 128


TOP: DNA Replication

25. The term neoplasm is another word for tumor.

ANS: T DIF: Memorization REF: p. 132


TOP: Changes in Cell Growth, Reproduction, and Survival

26. Atrophy and hypertrophy occur most often in fat cells as the body stores or uses fat.

ANS: F DIF: Memorization REF: p. 132


TOP: Changes in Cell Growth, Reproduction, and Survival

27. Protein synthesis is the central building process for cell growth and maintenance.

ANS: T DIF: Memorization REF: p. 121


TOP: Protein Synthesis

28. The “rungs” of the DNA ladder are made up of either deoxyribose sugar or phosphoric acid.

ANS: F DIF: Memorization REF: p. 121


TOP: Deoxyribonucleic Acid (DNA)

29. What differentiates one DNA nucleotide from another is whether it has a ribose or a
deoxyribose sugar.

ANS: F DIF: Memorization REF: p. 121


TOP: Deoxyribonucleic Acid (DNA)

30. The distance between the two uprights in the DNA ladder is always equal to the total distance
of one purine and one pyrimidine nitrogen base.

ANS: T DIF: Application REF: p. 121


TOP: Deoxyribonucleic Acid (DNA)

31. A DNA codon consists of three nucleotides.

ANS: T DIF: Memorization REF: p. 122


TOP: Deoxyribonucleic Acid (DNA)

32. A human gene is a segment of the DNA molecule.

ANS: T DIF: Memorization REF: p. 122


TOP: Deoxyribonucleic Acid (DNA)

33. A human gene is made up of about 250 DNA nucleotides.

ANS: F DIF: Memorization REF: p. 122


TOP: Deoxyribonucleic Acid (DNA)

34. Examples of noncoding RNA are messenger RNA and ribosomal RNA.

ANS: F DIF: Memorization REF: p. 122


TOP: Ribonucleic Acid (RNA)

35. Uracil must by a pyrimidine nitrogen base.

ANS: T DIF: Synthesis REF: p. 122 TOP: Transcription

36. If the original DNA was ATCGGA, the messenger RNA formed from this DNA would be
TUGCCT.

ANS: F DIF: Application REF: p. 122 TOP: Transcription

37. Editing of the mRNA begins when a modified adenine base is added to one end of the RNA
strand.

ANS: F DIF: Memorization REF: p. 123


TOP: Editing the Transcript

38. A polyribosome is making several copies of the same protein molecule.

ANS: T DIF: Application REF: p. 125 TOP: Translation

39. If the original DNA code was CAA, the transfer RNA for that strand of DNA would be CAA.

ANS: T DIF: Synthesis REF: p. 123 TOP: Translation

40. Anticodons make up part of the messenger RNA, because they are opposite of the DNA
codon.

ANS: F DIF: Application REF: p. 123 TOP: Translation

41. Transfer RNA carries amino acids to the ribosome where they are added to the protein being
built.

ANS: T DIF: Memorization REF: p. 123


TOP: Translation

42. The complete set of proteins that can be made by the cell is called its proteome.

ANS: T DIF: Memorization REF: p. 126


TOP: Translation

43. If a protein is not folded properly, chaperone proteins can break it down and recycle the
individual amino acids.

ANS: F DIF: Memorization REF: p. 126


TOP: Translation

44. The centromere holds two chromatids together.

ANS: T DIF: Memorization REF: p. 128


TOP: DNA Replication
45. Telomeres are strands of nucleotides at the end of the chromosome that are expendable and
are not needed for formation of proteins.

ANS: T DIF: Memorization REF: p. 128


TOP: DNA Replication

46. During prophase, chromosomes become chromatin, the nuclear membrane disappears, and
spindle fibers form.

ANS: F DIF: Memorization REF: pp. 129-130


TOP: Mitosis

47. Telophase is the last stage of mitosis, and if cytokinesis is going to occur it begins at this
stage.

ANS: T DIF: Memorization REF: p. 130


TOP: Mitosis

48. If the haploid number of chromosomes for a cell is 24, there would be 12 chromosomes in the
gamete.

ANS: F DIF: Application REF: p. 131 TOP: Meiosis

MATCHING

Match each of the terms related to protein synthesis with its corresponding statement or
definition.
a. mRNA
b. tRNA
c. Transcription
d. Translation
e. RNAi

1. Process that occurs when the double strands of a DNA segment separate and RNA nucleotides
pair with DNA nucleotides
2. Type of RNA that carries information in many groups of three nucleotides called codons, each
of which codes for a specific amino acid
3. Type of RNA that has an anticodon and binds to a specific amino acid
4. Process that involves the movement of the mRNA with respect to the ribosome
5. Can inhibit the process of protein synthesis

1. ANS: C DIF: Memorization REF: p. 122


TOP: Transcription, Translation
2. ANS: A DIF: Memorization REF: pp. 121, 122
TOP: Transcription | Translation
3. ANS: B DIF: Memorization REF: p. 122
TOP: Transcription, Translation
4. ANS: E DIF: Memorization REF: p. 125
TOP: Transcription | Translation
5. ANS: D DIF: Memorization REF: p. 123
TOP: Transcription | Translation
Match each phase of mitosis with its corresponding description.
a. Anaphase
b. Metaphase
c. Prophase
d. Telophase

6. Phase in which chromosomes become visible


7. Chromosomes align along the equator of spindle fibers
8. Chromosomes move toward opposite poles of the cell
9. Chromosomes elongate into chromatin form and spindle fibers disappear

6. ANS: C DIF: Memorization REF: p. 129


TOP: Major Events in Mitosis
7. ANS: B DIF: Memorization REF: p. 130
TOP: Major Events in Mitosis
8. ANS: A DIF: Memorization REF: p. 130
TOP: Major Events in Mitosis
9. ANS: D DIF: Memorization REF: p. 130
TOP: Major Events in Mitosis

Match each of the following terms with its definition or description.


a. Adenine
b. mRNA
c. Intron
d. RNAi
e. Uracil
f. Chaperone protein
g. Transcription
h. tRNA
i. Thymine
j. Exons
k. Proteasomes
l. Telomere
m. Centromere
n. Haploid
o. Diploid
p. Translation

10. This nitrogen base is found only in RNA.


11. This nitrogen base is found in both RNA and DNA.
12. This nitrogen base is found only in DNA.
13. This is the term used to describe the number of chromosomes in a gamete.
14. This is the term used to describe the normal number of chromosomes in most body cells.
15. These parts of the messenger RNA are removed and not sent to the ribosome.
16. These parts of the edited messenger RNA are sent to the ribosome.
17. This part of the chromosome is not replicated during DNA replication.
18. This structure holds two newly formed chromosomes together.
19. This can properly refold an improperly folded protein.
20. This can destroy an improperly folded protein before it can harm the cell.
21. This type of RNA carries information from the nucleus to the ribosome.
22. This type of RNA carries amino acids to the ribosome.
23. This type of RNA can prevent protein synthesis.
24. This process copies the DNA code to RNA.
25. This process results in a newly built protein.

10. ANS: E DIF: Memorization REF: p. 122


TOP: Deoxyribonucleic Acid (DNA)
11. ANS: A DIF: Memorization REF: p. 121
TOP: Deoxyribonucleic Acid (DNA)
12. ANS: I DIF: Memorization REF: p. 121
TOP: Deoxyribonucleic Acid (DNA)
13. ANS: N DIF: Memorization REF: p. 131
TOP: Meiosis
14. ANS: O DIF: Memorization REF: p. 131
TOP: Meiosis
15. ANS: C DIF: Memorization REF: p. 123
TOP: Editing the Transcript
16. ANS: J DIF: Memorization REF: p. 123
TOP: Editing the Transcript
17. ANS: L DIF: Memorization REF: p. 128
TOP: DNA Replication
18. ANS: M DIF: Memorization REF: pp. 129-130
TOP: DNA Replication
19. ANS: F DIF: Memorization REF: p. 126
TOP: Translation
20. ANS: K DIF: Memorization REF: p. 126
TOP: Translation
21. ANS: B DIF: Memorization REF: p. 126
TOP: Transcription
22. ANS: H DIF: Memorization REF: p. 123
TOP: Translation
23. ANS: D DIF: Memorization REF: p. 125
TOP: Translation
24. ANS: G DIF: Memorization REF: p. 122
TOP: Transcription
25. ANS: P DIF: Memorization REF: p. 123
TOP: Translation

OTHER

1. Describe the structure of a DNA molecule. What is the importance of the “triplet”?

ANS:
Answers will vary.

DIF: Application REF: p. 121 TOP: Deoxyribonucleic Acid (DNA)

2. Describe the process of transcription. What are introns and exons?


ANS:
Answers will vary.

DIF: Application REF: p. 122 TOP: Transcription

3. Describe the process of translation. What is RNAi?

ANS:
Answers will vary.

DIF: Application REF: p. 123 TOP: Translation

4. Describe the process of DNA replication.

ANS:
Answers will vary.

DIF: Memorization REF: p. 128 TOP: DNA Replication

5. Explain the process of mitosis. Explain what occurs in each step.

ANS:
Answers will vary.

DIF: Memorization REF: p. 129 TOP: Cell Replication

6. Explain the difference in the cells formed by mitosis and meiosis. Why is this difference
important?

ANS:
Answers will vary.

DIF: Application REF: p. 131 TOP: Meiosis


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similar teeth in the concave, the nails being driven ¹⁄₂ in. apart. The
fan consists of a small roller upon which four pieces of tin are nailed.
The beaters are larger rollers, into which wooden teeth are set. To
hold the cylinder, fan, and beaters in place, four posts and two
crosspieces were used, as shown.
Made as a Model, This Small Thresher Proved Useful for Various Grains and
Seeds

The power used is an 8-ft. windmill that I constructed, using a


buggy wheel as the frame. The cylinder must be run at a fairly high
speed, the fan nearly as fast, and the beaters may be run much
slower; this is taken care of by the relative size of the pulleys. The
screen between the fan and beaters must be of small mesh so that
grain will not fall through into the fan chamber. The sieve through
which the grain drops must be the proper size for grain, and can be
varied for the different kinds of grain or seed threshed. It is better to
put only the heads of grain into the thresher, as long straws twist
about the rollers. The material to be threshed is fed into the cylinder
in the usual manner, and takes its course as indicated by the arrows,
the grain falling to the spout at the bottom, and the straw and chaff
being blown out at the exhaust for it. Soft wood was used in the
construction, ⁷⁄₈-in. stock for the heavier pieces, and ³⁄₈ or ¹⁄₄-in. stock
for the other parts. The curved housing for the fan was made of tin.
Leather or rope belts, fitted tightly, may be used. The power is
applied on the cylinder pulley, hand or other power being suitable.—
F. E. Brimmer, Dalton, N. Y.
Moth-Ball Puzzle as Window-Advertising Novelty
A druggist recently puzzled thousands with a novel window
display. A small white ball in a 1-in. glass tube, about 10 in. long,
displayed in a show window, would sink to the bottom, then slowly
ascend, only to sink as before. A sign reading “What Makes It
Move?” kept the crowd guessing. The tube was apparently filled with
water. The construction is simple. The tube is about three-quarters
full of carbonated soda water. The white ball is an ordinary moth ball.
The ball sinks, and when it becomes soaked gradually as it lowers,
bubbles of gas cling to it, carrying it to the top of the solution. There
the gas escapes, destroying the ball’s buoyancy, and causing it to
sink again, This process is repeated over and over.—David J.
Lonergan, Minneapolis, Minnesota.
Record-Cleaning Pad Fixed to Talking Machine
By providing a practical method of keeping talking-machine
records free from dust automatically, as they are played, the life of
the record is prolonged and the reproductions are more clear, and
free from scratching sounds. A felt pad supported on a fixture made
of a strip of brass does the work nicely. The pad is clamped in a clip
at the end of the brass strip, and the entire device is held in place by
the spring action of the upper clip, which fits over the end of the
reproducing arm. The pad or the whole device can be slipped out of
place quickly.
Novel Uses for Safety Pins

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