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Trabecular Meshwork

dr Ficky Ferliando Irwan


Trabecular Meshwork
A circular spongework of connective tissue

Lined by trabeculosytes

Contractile properties  Influence


outflow resistance

Phagocytic properties
Layer of trabecular meshwork

Uveal Corneoskleral Juxta


trabecular meshwork canalicular
meshwork tissue
Uveal Trabecular Meshwork
cordlike trabeculae

Elastic fiber <<<

trabeculocytes contain pigment


granule

less circular and larger than


corneoscleral
Corneoscleral Meshwork
consists of a series of thin, flat, perforated
connective tissue sheets

trabecular beam  covered by a monolayer of thin


trabecular cells exhibiting multiple pinocytotic

the inner core consists of collagen


and elastic fibers.
Pericanalicular Connective Tissue

invests the entire extent of the


schlemm canal
Lies between the outermost
layers of the corneoscleral forming a loose
meshwork and the network
endothelial lining of the
schlemm canal

Endothelial
meshwork
Makes aqueous humor makes the greatest
can percolate to reach contribution to
the endothelial lining of outflow resistance
the Schlemm canal
Schlemm Canal

a circular tube closely resembling a


lymphatic vessel
Schlemm Canal…

Larger vesicles = giant


vacuoles
along the lined by a size and contribute to
in ternal single number the
canal wall membrane are pressure-
dependent
increased outflow of
by aqueous
increasing
intraocula
r pressure
Collector Channel

25-30 collector channels arise from the


Schlemm canal and drain into the deep
and midscleral venous plexuses

Up to 8 of these channels drain


directly into the episcleral venous
plexus as aqueous veins
Collector Channel …

Thickening of trabecular Loss of endothelial


sheets cellularity

Aging
Factor
Increase in connective Accumulation of debris in
tissue the meshwork and
glycosaminoglycans in the
extracellular space
Thank You

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