RĪGA STRADIŅŠ UNIVERSITY

STUDY PROGRAM “MEDICINE 2.0”

STUDY COURSE “MEDICAL BIOCHEMISTRY”
SEMESTER II
WEEK 2
HOMEWORK

Fill out these worksheets while listening to Lecture for this week – “Fatty acid catabolism, ketogenesis”
Assignments:
 Fill out the table, giving general description of the metabolic process.

 Name/draw missing substrates, products, enzymes and cofactors in the schematic drawings.

TASK 1

Name of the metabolic process

Place of action in organism and in cell Org- cells with mitochondria, except brain cells. In cell- cytosol/intermembrain space of mitochondria/matrix of mito.

ma
Describe the major function/s of the
metabolic process

Use 2ATP
ATP gained/used
(including coenzymes)

Draw carnitine molecule:

TASK 2

Name of the metabolic process

Place of action in organism and in cell

 Substrate- Acyl-CoA. Prod- Acyl-CoA (N-2C) + acetyl-CoA+ NADH+ FADH.
Substrate and products

To produce Acetyl-CoA for citric acid cycle to make electrons to produce ATP in Electrone-transfer chain
Describe the major function/s of the
metabolic process

1 NADH = 2,5 ATP, 1 FADH= 1,5ATP. =4 ATP in total

ATP gained/used
1)Beta oxidation (1NADH + 1FADH every cycle)+ Cytric acid cycle. (3NADH + 1FADH every cycle)
(including coenzymes)
 TASK 3

Name of the metabolic process

Place of action in organism and in cell

Substrate and products

Describe the major function/s of the

metabolic process

ATP gained/used
(including coenzymes)