1. Which of the following statement is not
Most clinically useful local anesthetic
true regarding difficulty of reachieving
profound anesthesia?
 Patient may develop allergic reaction
after administration of local anesthetic
2. Stimulation of beta receptors produces
the following, except:
 Vasoconstriction
3. Stimulation of alpha receptors by a
sympathomimetic drug usually
produces a response that includes
 Reuptake and vasoconstriction
4. Which of the following is a pure alpha
adrenergic agonist?
 Phenylephrine
5. Which of the following is a pure β-
adrenergic agent?
 Isoproterenol
6. The maximum dose of epinephrine in
healthy adult patient is
 .2 mg
7. The maximum dose of norepinephrine
1:30,000 healthy adult patient is
 .34 mg
8. Levonordefrin is available commercially
as
 Neo-cobefrin
9. It is considered as the weakest
vasoconstrictor
 Neo-synephrine
10. Levonordefrin should be avoided in
patients who are taking
 Tetracyclic antidepressants
11. Stimulation of this sympathetic
produces reuptake of the drug
 Alpha 2 receptor
12. The following factors may influence the
rapid absorption of local anesthetic,
except
 Application of cold in the
injection site
13. The vasodilator activity of local
anesthetics affect
 Onset of action and duration
14.
are classified as _____ based on mode
of action
 Class D agent
15. The hydrophilic group in local
anesthetic agent is usually made up of
 Tertiary amine
16. Regional anesthesia is contraindicated
in the following cases, except
 Minor infection
17. Which of the following is the local
anesthesia of choice for patients with
plasma cholinesterase deficiency
 Mepivacaine
18. The local anesthetics suitable for use in
dentistry as topical anesthetic agent
include
 Benzocaine and lidocaine
19. The patient developed allergy after
administration of amide type of local
anesthetics. The most probable cause is
due to
 Methylparaben
20. Faulty technique in the induction of
local anesthesia will most likely result in
21. In large doses, the anesthesia solution
should be avoided in patients suffering
from idiopathic methemoglobinemia
 Prilocaine
22. Which of the following is considered as
short acting anesthetics?
 4% prilocaine
23. Amide type of local anesthetics undergo
biotransformation primarily in the
 Liver
24. The only anesthetic which causes
vasoconstriction is
 Cocaine
25. Which of the following has the greatest
protein-binding capacity?
 Bupivacaine
26. The use of epinephrine for local
hemostasis during surgery might result
in
  Cardiac arrhythmia  Mepivacaine
27. The directly acting sympathomimetic 40. Local anesthetic drugs block
amines exert their actions directly on  Sensory conduction only
adrenergic receptors and include the 41. The anesthetic drug that produces
following, except: powerful stimulation of cerebral cortex
 Amphetamines is
28. Drugs that will temporarily interrupt  Cocaine
propagation of impulse when injected 42. When vasoconstrictors produce
into the tissue is called constriction of arterioles, the site of
 Local anesthetics action is at which receptor?
29. Which of the following is not an adverse  Alpha
effect of vasoconstrictors? 43. Each of the following drugs is
 Hypotension considered to be an indirect-acting
30. Alpha or beta adrenergic blocking agent catecholamines, except
functions by  Dopamine
 44. The first sensation usually lost after
31. Which of the following is a brand name administration of a local anesthetic is
of Bupivacaine?  Pain
 Sensorcaine 45. Which of the following is a local
32. Stimulation of beta 2 adrenergic anesthetic subject to inactivation by
receptors produces plasma esterases?
 Bronchodilation 46. Local anesthesia interfere with the
33. Vasoconstrictors are use with local transport of which of the following ions
anesthetics to _____, except during drug-receptor interception?
  Sodium
34. Epinephrine stimulates these 47. EMLA is a mixture of
adrenergic receptors in the  Lidocaine and prilocaine
cardiovascular system 48. High pH (basic) of LA tends to shifts
 Alpha and beta toward the free base form resulting to
35. Which of the following is endogenous formation of more RN
cathecholamine?  The statement is true
 Dopamine 49. Low PH (acidic) of LA tends to shifts
36. Which of the following is not a toward the cationic form resulting to
requirement of an ideal local anesthetic formation of more RNH+
agent  The statement is true
 Its effect must be irreversible 50. The role of sodium metabisulphite in
37. Effectiveness of a local anesthetic local anesthetic agent is:
depends on the following, except  Reducing agent
 Acidic tissue pH 51. Symptoms of epinephrine overdose
38. At which tissue pH will the local following a local anesthetics injection
anesthetic be effectively diffused? may include all the following, except
 7.4  hypotension
39. Which of the following exhibits weakest 52. trismus during block anesthesia is a
effectivity as a topical anesthetics? result of
  damage to medial pterygoid 65. All are true about use of articaine in a
muscle child except:
53. mandiblock is given in  Two times as potent as
 pterygomandibular space lidocaine, mepivacaine, and
54. the primary organ for the excretion of prilocaine
local anesthetic and its metabolites is 66. The maximum recommended dose of
the Articaine in healthy patient is
 kidney  7mg/kg
55. sodium bicarbonate when given with 67. During mandiblock, local anesthetic
local anesthetic has which of the solution is deposited as close as
following effect? possible to the
 Increase onset and depth of 68. The following affects the duration of
anesthesia local anesthesia except:
56. All of the following are complication of  non-nervous tissue diffusibility
LA toxicity, except 69. Which space has highest chance of
 Paraesthesia infection with the injection of classical
57. Bupivacaine, a local anesthesia agent, is inferior alveolar nerve block?
used in dentistry in the concentration of  Pterygomandibular space
 0.5% 70. Which of the following anesthetic
58. The site of action of local anesthetics is agents would be preferred in lengthy
on the dental procedure?
 Nerve membrane  Vivacaine
59. Oraqix is used for 71. The absolute maximum dose of
 Anesthetizing intact mucosa lidocaine in healthy patient is:
60. The most common emergency seen  500 mg
after the use of local anesthesia is 72. The absolutely maximum dose of
 Syncope Prilocaine in healthy patient is:
61. Properties of local anesthetics include  600 mg
all of the following except: 73. It is considered as the safest of all local
 Low affinity for channels in anesthetics
resting state  Septocaine
62. Which of the following will happen if 74. All are true about use of Benzocaine,
intravascular injection of LA with except:
epinephrine was done accidentally?  Inhibits the antibacterial action
 Hypertension + tachycardia of amoxicillin
63. A patient who had history of hepatitis a 75. Difficulty of reachieving profound
month ago should ne preferably given anesthesia maybe attributed to the
which anesthetic agent? following, except
 Procaine  hyperkalemia
64. Which one of the following technique of 76. With over dosage of LA agent, one
local anesthesia requires extraoral would observe:
landmarks?  Hypotension
 Gow Gates 77. The role of sodium metabisulphite in
local anesthetic agent is:
  Reducing agent 90. Which of the following intravenous
78. Allergic reactions in patients who induction agents is most suitable for
receive amide type of local anesthetics day care surgery?
for dental procedures are most likely  Propofol
caused by the reaction of: 91. The agent of choice to reverse status
 Methylparaben epilepticus inducted by local anesthetic
79. ECG changes can first be observed overdose is:
when level of lignocaine is more than:  Diazepam
 5-6 mcg/ml 92. Toxic effect of local anesthetic include:
80. Which of the following is not used as a  All of the above
topical LA? 93. All of the following drugs are used for
 Procaine anesthetic emergencies except:
81. Local anesthetic is not effective in an  Amoxycillin
inflamed tissue because: 94. The anatomical landmark used during
 PH is more acidic, so LA is posterior superior alveolar nerve block
ineffective are mucobuccal fold, occlusal plane,
82. The earliest sign of syncope is: coronoid process and:
 Pallor  Anterior border of ramus
83. For extraoral maxillary nerve block, the 95. During mandibular nerve block, which
target area is: nerve might also get damaged?
 Anterior lateral pterygoid plate  Facial
84. Which combination forms day care 96. The sudden appearance of dumbbell
anesthesia? shaped swelling during third molar
 Fentalyn, propofol, isoflurane nerve block is mainly due to:
85. Kelsey Fry Technique refers to the  Injection in pterygoid plexus
removal of: 97. The maximum concentration of
 Impacted mandibular third lidocaine for topical block is:
molars  4%
86. Nerve anesthetized in incisive nerve 98. Which of the following are the theories
block are: of regional anesthesia?
 Incisive and mental nerve  Specific receptor theory and
87. A patient presents with trismus. Which membrane expansion theory
of the following technique will block 99. The maximum dose of LA must be
mylohyoid nerve, incisive, and long reduced when used in combination with
buccal nerve? a CNS/respiratory depressant because, I
 Akinosi’s technique may result in:
88. Pterygomandibular space contains all  All of the above
except: 100. True regarding EMLA is:
 Long buccal nerve  It is a mixture of 24 mg/g
89. Which one of the following local lidocaine and 25 mg/gm
anesthetics belongs to the ester group? prilocaine used for skin
 Procaine anesthesia
101. The gas used in LA cartridge is:
 Nitrogen
102. A painless, fluid filled retention
cyst appearing in the area of recent
dental treatment may be the result of:
 Injury to salivary gland
103. Eutectic mixture of 2.5%
lignocaine and 2.5% prilocaine is used
for:
 Anesthetizing intact mucosa
104. In CPR, the sternum should be
depressed at the rate of:
 2 inches per second
105. Properties of local anesthetics
include all of the following except:
 Low affinity for channels in
resting state
106. Nitrous oxide alone is not used
as a GA agent because of:
 Difficulty in maintaining an
adequate oxygen concentration
107. Fibers which transmit fast pain
from pulp are:
 A delta
108. In posterior superior alveolar
nerve block, the needle is advanced in
an:
 Upward, inward and backward
position
109. The head tilt procedure while
dealing with an unconscious patient in
dental chair is done to ensure:
 Patient airway
110. For Propofol all are true except:
 Causes vomiting after use
111. Which among the following
should be the last resort for giving LA
technique to the patient?
 Intrapulpal
112. When soft palate is paralyzed,
which is not seen?
 Clefting of the palate
113. The potential action of all the
local anesthetics depends upon the
ability of anesthetics salt to liberate the
free:
 Alkaloidal base
114. Local anesthetics block nerve
conduction by:
 Decreasing the membrane
permeability to Na+ ions
thereby stabilizing nerve
membrane
115. Anterior trunk of mandibular
branch of trigeminal nerve supply all
except:
 Medial pterygoid
116. Gate control theory of pain is
due to:
 Substantia gelatinosa
117. Infraorbital anesthesia involves
which nerve?
 Anterior superior alveolar nerve
118. Objective signs of inferior
alveolar nerve block are seen in:
 Unilateral midline between
premolars and incisors
119. A ligamental injection of 2%
lidocaine with 1:10000 epinephrine will
cause the pulp circulation to:
 Cease for about 30mins
120. Local anesthetics with lowest
placental transfer rate is:
 Chloroprocaine
121. One of the disadvantages of
breech loading, metallic type, self-
aspirating, cartridge type syringe is:
 Weight
122. Which of the following
technique of local anesthesia requires
extraoral landmarks?
 Gow Gates
123. Which of the extraoral
landmark for Gow Gates technique of
mandibular nerve block?
 Corner of the mouth and
intertragic notch
124. All are true about use of
articaine in a child except:
  Only amide local anesthetics
that also contains an ester
group
125. Most potent topical anesthetic
is: tetracaine
126. Maximum permissible dose of
articaine in healty patient is: 7mg/kg
127. LA is deposited in inferior
alveolar nerve block at: lingual
128. The following affects the
duration of local anesthesia except:
non-nervous tissue diffusibility
129. Local anesthetic with highest
local tissue irritancy is: bupivacaine
130. Which space has highest chance
of infection with the injection of
classical inferior alveolar nerve block?
 Pterygomandibular space
131. The absolute maximum dose of
lidocaine in healthy patient is: 500 mg
132. The absolutely maximum dose
of Prilocaine in healthy patient is: 600
mg
133. It is considered as the safest of
all local anesthetics
 Septocaine
134. Epinephrine is: an alcohol
derivative
135. In inferior alveolar nerve block,
the needle should not penetrate more
than: 1/8 inch
136. The dissolution constant of
Lidocaine HCl is: 7.7
137. Deep injections are avoided if
the patient is
138. This injection technique secures
regional anesthesia by depositing a
suitable amount of anesthetic solution
within close proximity to a main nerve
trunk
 Nerve block
139. Five minutes after inferior
nerve block is administered, the patient
develops paralysis of the forehead,
eyelid and upper li on the same side of
the face. This may be result of
 Injection of anesthetic solution
into the capsule of the parotid
gland and consequent blockade
of CN VII
140. The nerve anesthetized in the
infraorbital nerve block are the
following, except: PSA nerve
141. Hydrolysis of Procaine HCl
occurs mainly in the:
142. Patient with very limited mouth
opening can receive all the following
injection techniques, except: Gow-
Gates Technique
143. The direct-acting adrenergic
amines exert their actions directly on
adrenergic receptors and include the
following, except: Amphetamine
144. Parasympathomimetic drugs
produce which of the following?
145. Which one of the following is
classified as short duration local
anesthetics?
 4% prilocaine HCl
146. In large doses, this anesthetic
solution should be avoided in patients
suffering from idiopathic
methemoglobinemia
 None of the above
147. In adult patients, about ____
should be deposited during
nasopalatine nerve block
 .45 ml
148. The closed-mouth approach to
the inferior alveolar nerve is known as
the
 Akinosi technique
149. Commercially injectable local
anesthetics are usually
 Acidic
150. Long duration local anesthetics
usually last for: 90 minutes
151. If anesthesia of the mandibular
incisors only is required, it is possible to
use which of the following injection
techniques
 Inferior alveolar nerve block
152. Catecholamines have the
following characteristics, except
 They have hydroxyl
substitutions in the 3rd and 4th
positions of the aromatic ring
153. Vasoconstrictors not having
hydroxyl groups in the 3rd and 4th
position of the aromatic molecule are:
not cathechols
154. This vasoconstrictor is not
recommended in dentistry because it
may cause tissue damage: dopamine
155. The only local anesthetic with
thiophene attached to the aromatic ring
is: Articaine