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Biology A
Scheme of work
Module 2: Foundations in biology
Topic 2.1: Foundations in biology
MCQ - Biochemistry1
MCQ - Biochemistry2
Additional guidance:
To include roles of the enzymes helicase, DNA polymerase. Importance of
replication in conserving genetic information with accuracy and the
occurrence of random, spontaneous mutations.
To include non-overlapping, degenerate and universal nature of the code
Role of RNA polymerase, mRNA, tRNA, rRNA
Synoptic links:
- DNA sequencing and genetic engineering
- Enzymes
- Function of eukaryotic organelles
Synoptic links:
- Hormones
- Biological molecules – Qualitative tests
MCQ- Enzymes
Synoptic links:
- Chemiosmosis in respiration and photosynthesis
- Features of exchange surfaces
Additional guidance:
Cell cycle – G1, S and G2, mitosis and cytokinesis
To include the changes in the organelles during mitosis and meiosis
Cells are specialised - erythrocytes, neutrophils, squamous and ciliated
epithelial cells, sperm cells, palisade cells, root hair cells and guard cells.
Including squamous and ciliated epithelia, cartilage, muscle, xylem and
phloem as examples of tissues
Potential use of stem cells in research and medicine to include: repair of
damaged tissues, the treatment of neurological conditions such as
Alzheimer’s and Parkinson’s, and research into developmental biology
Synoptic links:
- Prokaryotic and eukaryotic cells.
- Cell specialisation and level of organisation
- Proteins and enzymes
Additional guidance:
Cladistics and phylogenetic definition of species (A level)
the contributions of Darwin and Wallace in formulating the theory
of evolution by natural selection AND fossil, DNA (only genomic
DNA at AS level) and molecular evidence
Synoptic links:
- Membranes and their structure
- Movement of substances
- Animal responses
5.1.4 Hormonal 9 hours 5.1.4 Hormonal PAG 9.3 Qualitative testing Resources:
Communication Communication glucose – Opportunity to use
Introduction to endocrinology – endocrine system
urine samples in diagnostic
tests. Introduction of diabetes by analysing urine samples record data
and suggesting reasons as to why glucose might be present in
urine.
Use of pancreas’ photomicrographs from online. Interactive
microscope slides: pancreas, interlobular ducts, islets of
PAG 1 Microscopy –
Langerhans
Opportunity to observe
pancreas tissue under the Case studies of people with diabetes.
microscope and practice Video- This is diabetes
drawing skills.
Additional guidance:
The use of insulin produced by genetically modified bacteria and
the potential use of stem cells to treat diabetes mellitus
Maths opportunities to carry out calculations of magnification
Synoptic links:
- Protein structure
- Cell membranes
- Qualitative tests
- Homeostasis
- Movement of substances
- Genetic Engineering (GCSE)
Synoptic links:
- Synapses
- Protein structure
- ATP
- Cardiac Cycle
Additional guidance:
PAG12.1 Investigation into Maths opportunity to calculate respiratory quotient (RQ), plot and
the respiration rate of interpret graphs
Saccharomyces cerevisiae –
OCR suggested activity
Synoptic links:
- Cell signalling
- Manipulating genome
Additional guidance:
DNA sequencing, need to know the scientific knowledge and
have an understanding of how it develops over time.
Synoptic links:
- Biological molecules
- Nucleotides and nucleic acids
6.2.1 Cloning and 15 hours 6.2.1 Cloning and PAG7 Microbiology Resources:
biotechnology biotechnology OCR suggested activities
Debates on the ethical issues for and against cloning and
biotechnology
Cauliflower cloning – Tissue
Culture and micropropagation Articles on cloning – Scientists have cloned monkeys and it could
– SAPS help treat cancer
Antimicrobial agent – University of Birmingham (Video)
PAG 4 – Enzymes rate of
reactions Additional guidance:
Maths opportunities for growth curves including log growth,
calculating rates of reactions, plotting and interpreting graphs.
Synoptic links:
- Enzymes
- Mutations
- Serial dilutions
Synoptic links:
- Measuring biodiversity
- Photosynthesis
- Evolution
Additional guidance:
Include the economic, social and ethical reasons for conservation
of biological resources
Include timber production and fishing in the management of an
ecosystem.
Synoptic links:
- Biodiversity
- Classification and evolution
MCQ - Ecosystems
Document updates:
V1.1 February 2019 Addition of section 3.1.3f. Additional notes for: 3.1.2 f, 4.2.1 b, 6.2.1 h
V2.0 June 2019 Addition of Suggested practical work and resources/links in the ‘Notes’ column. Removed learning outcome
column.
V2.1 April 2022 Removal of PAG 9 as a suggested practical work, for spec reference ‘2.1.3 Nucleotides and nucleic acids’
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