TABLE OF CONTENTS

May 2023  Volume 256 Copyright ª 2023 by Elsevier Inc.

Editorials
Familial Hypercholesterolemia: The Atlantic Divide
Samuel S. Gidding, MD ......................................................................................................................................................................................... 1

EUROPEAN PAEDIATRIC ASSOCIATION PAGES

Lost in Transition: The Issue of Vanishing Unaccompanied Alien Children in Europe
Massimo Pettoello-Mantovani, MD, PhD, Tudor Lucian Pop, MD, Ida Giardino, MD, Mehmet Vural, MD, Flavia Indrio, MD, and
Pietro Ferrara, MD ................................................................................................................................................................................................. 3

Original Articles
Airway Impedance: A Novel Diagnostic Tool to Predict Extraesophageal Airway Inflammation
Rachel Rosen, MD, MPH, Reza Rahbar, DMD, MD, Karen Watters, MD, Anne Hseu, MD, Carlos J. Munoz, MD, Lynne Ferrari, MD,
Robert Holzman, MD, Shoaib Mohammad, MD, Alexandra Cohen, BA, Maritha Du, BA, Anna Akkara, BS, Andrea Catacora, BS,
Tregony Simoneau, MD, Sarah Connearney, MSN, RN, CNP, Paul Mitchell, MS, and Samuel Nurko, MD, MPH ................................... 5

Cost-Effectiveness of Management Strategies in Recurrent Acute Otitis Media

Kathleen A. Noorbakhsh, MD, MS, Hui Liu, MS, Marcia Kurs-Lasky, MS, Kenneth J. Smith, MD, MS, Alejandro Hoberman, MD, and
Nader Shaikh, MD, MPH ...................................................................................................................................................................................... 11

Pediatric Recurrent Pericarditis: Appropriateness of the Standard of Care and Response to IL-1
Blockade
Roberta Caorsi, MD, Antonella Insalaco, MD, Francesca Bovis, PhD, Giorgia Martini, MD, Marco Cattalini, MD, PhD,
Marcello Chinali, MD, Alessandro Rimini, MD, Chiara Longo, MD, Silvia Federici, MD, PhD, Camilla Celani, MD,
Giovanni Filocamo, MD, PhD, Rita Consolini, MD, Maria Cristina Maggio, MD, Gloria Fadanelli, MD, Francesco Licciardi, MD,
Micol Romano, MD, Barbara Lia Teruzzi, MD, Andrea Taddio, MD, PhD, Angela Miniaci, MD, Francesco La Torre, MD,
Alessandro De Fanti, MD, Giulio Cavalli, MD, Barbara Bigucci, MD, Romina Gallizzi, MD, Matteo Chinello, MD, Massimo Imazio, MD,
Antonio Brucato, MD, Rolando Cimaz, MD, Fabrizio De Benedetti, MD, and Marco Gattorno, MD......................................................... 18

The Hip of Children with Congenital Zika Syndrome: A Prospective Observational Study
Jakeline Oliveira da Fonseca, MD, MsC, Renata Artimos de Oliveira Vianna, MD, PhD, Fabiana Rabe Carvalho, PhD,
Luis Guillermo Coca Velarde, PhD, Solange Artimos de Oliveira, MD, PhD, Claudete Aparecida Ara
ujo Cardoso, MD, PhD, and
Vin
ıcius Schott Gameiro, MD, PhD ..................................................................................................................................................................... 27

– contains additional content that can be found at www.jpeds.com

The Journal of Pediatrics (ISSN 0022-3476) is published monthly by Elsevier Inc., 230 Park Avenue, Suite 800, New York, NY 10169-0901, USA. Periodicals
postage paid at New York, NY and additional mailing offices. POSTMASTER: Send address changes to Elsevier, Journal Returns, 1799 Highway 50 East,
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Cost-Effectiveness of a Quality Improvement Initiative for the Clinical Management of Children with
Newly Diagnosed Immune Thrombocytopenia
Alexandra Moskalewicz, BSc, Carolyn E. Beck, MD, MSc, Patricia C. Parkin, MD, Michaela Cada, MD, MPH, and Myla E. Moretti, PhD 33

Cost-Effectiveness of Newborn Screening for Phenylketonuria and Congenital Hypothyroidism

Kajsa Appelberg, MEcon, Lene S€
orensen, Med Lic, Rolf H. Zetterstr€ om, MD, PhD, Martin Henriksson, PhD,
Anna Wedell, MD, PhD, and Lars-Ake Levin, PhD ............................................................................................................................................ 38

Evolution of Ultrasound-Assessed Lung Aeration and Gas Exchange in Respiratory Distress Syndrome
and Transient Tachypnea of the Neonate
Lucilla Pezza, MD, Victor Sartorius, MD, Barbara Loi, MD, Giulia Regiroli, MD, Roberta Centorrino, MD, Lucia Lanciotti, MD,
Virgilio P. Carnielli, MD, PhD, and Daniele De Luca, MD, PhD...................................................................................................................... 44

Healthcare Costs of Major Morbidities Associated with Prematurity in US Children’s Hospitals

Kuan-Chi Lai, MD, MPH, and Scott A. Lorch, MD, MSCE .............................................................................................................................. 53

Association of Postnatal Growth Changes and Neurodevelopmental Outcomes in Preterm Neonates of

<29 Weeks’ Gestation
Nicole Bando, MSc, Tanis R. Fenton, PhD, RD, Junmin Yang, MSc, Linh Ly, MD, Thuy Mai Luu, MD, MSc, Sharon Unger, MD,
Deborah L. O’Connor, PhD, RD, and Prakesh S. Shah, MD, MSc, for the Canadian Neonatal Network and Canadian Neonatal Follow-Up
Network Investigators ............................................................................................................................................................................................ 63

Substance Exposure and Adverse Neonatal Outcomes: A Population-Based Cohort Study

Amna Umer, PhD, Emma Watson, BS, Christa Lilly, PhD, Sara Woods, BS, Candice Lefeber, MPH, Janine Breyel, MA, and
Collin John, MD, MPH ......................................................................................................................................................................................... 70

Prenatal and Childhood Smoke Exposure Associations with Cognition, Language, and Attention-Deficit/
Hyperactivity Disorder
Bernard F. Fuemmeler, PhD, MPH, Trevin E. Glasgow, PhD, Julia C. Schechter, PhD, Rachel Maguire, MPH, Yaou Sheng, MPH,
Tatyana Bidopia, BS, D. Jeremy Barsell, MS, Albert Ksinan, PhD, Junfeng Zhang, PhD, Yan Lin, PhD, Cathrine Hoyo, PhD,
Susan Murphy, PhD, Jian Qin, PhD, Xiangtian Wang, MS, and Scott Kollins, PhD ...................................................................................... 77

Relationship Between Feeding to Sleep During Infancy and Subsequent Childhood Disease Burden
Eun Kyo Ha, MD, Ju Hee Kim, MD, Hye Ryeong Cha, BS, Won Seok Lee, MD, Seung Won Lee, MD, PhD, and
Man Yong Han, MD .............................................................................................................................................................................................. 85

Predictors of Intensive Care Admission in Hypoxemic Bronchiolitis Infants, Secondary Analysis of a

Randomized Trial
Donna Franklin, PhD, BN, MBA, Franz E. Babl, MD, MPH, FAAP, FRACP, FACEP, Jocelyn Neutze, MBChB, FRACP, FACEM,
Simon Craig, MBBS, FACEM, MHPE, MPH, Ed Oakley, MBBS, FACEM, Jeremy Furyk, MBBS, MPH&TM, MSc, FACEM,
Chris M. Frampton, PhD, Nadia Hasan, MBBS, Trang MT. Pham, BEng, MEng, Letitia Miller, BN,
John F. Fraser, MBChB, PhD, FRCP (Glas), FRCA, FFARCSI, FCICM, Stuart R. Dalziel, MBChB, FRACP, PhD, and
Andreas Schibler, MD, FCICM, A Pediatric Acute Respiratory Intervention Study (PARIS) on behalf of PREDICT................................. 92

Diagnostic Performance and Patient Outcomes With C-Reactive Protein Use in Early-Onset Sepsis
Evaluations
Miren B. Dhudasia, MBBS, MPH, William E. Benitz, MD, Dustin D. Flannery, DO, MSCE, Lori Christ, MD, David Rub, MD,
Giulia Remaschi, MD, Karen M. Puopolo, MD, PhD, and Sagori Mukhopadhyay, MD, MMSc .................................................................. 98
 TABLE OF CONTENTS

A Randomized Trial of an Exclusive Human Milk Diet in Neonates with Single Ventricle Physiology
Cynthia L. Blanco, MD, Amy Hair, MD, Lindsey B. Justice, DNP, Dantin Roddy, MD, Krista Bonagurio, RD, Patricia K. Williams, MD,
Desiree Machado, MD, Bradley S. Marino, MD, Annie Chi, MD, Cheryl Takao, MD, Erin E. Gordon, DO, Amir Ashrafi, MD,
Nicole Cacho, DO, MPH, Jay D. Pruetz, MD, John M. Costello, MD, MPH, and David S. Cooper, MD, MPH, on behalf of the Cardiac
Neonate Nutrition Study Group ........................................................................................................................................................................... 105

Ferric Carboxymaltose Versus Ferrous Fumarate in Anemic Children with Inflammatory Bowel Disease:
The POPEYE Randomized Controlled Clinical Trial
Nanja Bevers, MD, Els Van de Vijver, PhD, MD, Arta Aliu, Ashkan Rezazadeh Ardabili, MD, Philippe Rosias, MD, PhD,
Janneke Stapelbroek, MD, PhD, Imke A. Bertrams Maartens, MD, Cathelijne van de Feen, MD, Hankje Escher, MD, PhD,
Annemarie Oudshoorn, MD, Sarah Teklenburg, MD, PhD, Saskia Vande Velde, MD, PhD, Bjorn Winkens, PhD,
Maarten Raijmakers, PhD, Anita Vreugdenhil, MD, PhD, Marieke J. Pierik, MD, PhD, and Patrick F. van Rheenen, MD, PhD............. 113