M.Sc.

-I, Paper Name- Research Methodology

Question Bank

1. State difference between 'variance' and 'coefficient of variation'

2. Define ensemble and mentions different types of ensembles.
3. What is a "null hypothesis"?
4. Define standard deviation
5. Give full form of ISSN and ISBN.
6. List any two docking programs used in drug-design.
7. Define the terms 'h-index' and '- index"?
8. Explain the term computational methods. List the computational methods used in
drug discovery.
9. Elaborate the term Chemometrics.
10. Comment on Computer application in Chemistry and its significance.
11. Compare between qualitative and quantitative research.
12. Define accuracy and precision. Write the expression for student t-test and F-test.
13. What is the average citation?
14. What is i-10 index?
15. What is the h-index of the author?
16. Write in brief about impact factor of the journal and how it is calculated?
17. What is Science Citation Index".
18. List any 10 SCI journals.
19. Compare between research report and research publication.
20. Comment on Database in Chemistry.
21. What is ISSN, ISBN, DOI?
22. Mention any two cut-off methods used in MD simulation.
23. What is detection limit?
24. The square of standard deviation is called as
25. Define chemometrics.
26. Comment on Computer application in Chemistry and its significance.
27. Define accuracy and precision.
28. Write the expression for student t-test and F-test.
29. Comment on Database in Chemistry.
30. Give the expression for the Lennard-Jones which is one of the most widely used
functions for the Van Der Waals potential.
31. Define absolute error
32. List the packages used for doing molecular dynamic simulation.
33. Give the names of any two packages used in docking study.
34. Give the names of few online databases available for literature search.
35. Give the correct sequence of steps for performing molecular dynamic simulation?
36. If the standard deviation in measuring the diameter d of a sphere is 0.02 cm with d
2.15 cm then the standard deviation in the calculated volume V of the sphere will
be---------------
37. Define sample standard deviation.
38. Concordance of a series of measurements of same quantity is calculated as……...
39. Define "significant figures" in a number.
40. Give the steps required in a formulation of a research problem.
41. What is the use of scifinder?
42. The books and journals are coded by unique numbers. These are as-------
43. What is detection limit?
44. The relative standard deviation is called as
45. State difference between va
 Long Questions 10 Marks

1. Give brief account on classification of methods with suitable example

2. What is plagiarism? As a researcher, what care you should take to avoid
plagiarism?
3. Write in brief on writing a scientific report .
4. Briefly discuss the methods of chemometrics.
5. Write note on computational tools and its utility in research. List the computational
tools commonly used for research.
6. Elaborate the concept of computer based information systems. Justify how it had
been useful in your present research work.
7. What are the criteria for choice of Analytical method? State the general steps
required for quantitative analysis.
8. List the personal errors and state the measures to minimize the same.
9. The analysis of iron ore sample gave following percentage values for iron content:
7.08, 7.21, 7.12, 7.09, 7.16. 7.14, 7.07, 7.14, 7.18, and 7.11. Find out the mean,
standard deviation and coefficient of variation for the values.
10. Explain i) Hypothesis ii) Formulating a research problem.
11. Ellaborate the following:
i) Sources of literature ii) Compare between Conference and Workshop
12. Mention methods used in drug docking and give details of any one of them.
13. Give detailed account on statistical aids used to test the hypothesis.
14. Write in detail preparation of effective slides
15. Write note on computational tools and its utility in research. List the computational
tools commonly used for research.
16. Write in detail on method of propagation of errors to evaluate uncertainties in
experimentally observed and derived properties.
17. Write about the research methodologies for design and implementation of research
plan.
18. What tools are available for online literature search? Explain them in brief.
19. Give the classification of quantitative methods and describe them in short. Write
the general steps required for quantitative analysis.
20. Give detailed procedure for calculating slope and intercept of a straight line linear
equation along with errors estimates in the slope and intercept using least square fit
analysis,
21. The following results were obtained in the replicate analysis of a blood sample for
its lead content: 0.752, 0.756, 0.752, 0.751 and 0.760 ppm Pb. Calculate the mean
and the standard deviation as well as standard error of a mean of this set of data.
22. b) An AAS method for determination of copper in fuels yielded a pooled standard
deviation of 0.32 μg Cu/ml. The analysis of an oil from a reciprocating aircraft
engine showed a copper content of 8.53 μg Cu/ml. Calculate 90% and 99%
confidence limits if it was based on
a) a singly analysis
b) the mean of 4 analyses and
c) the mean of 16 analysis
23. Give detailed account of writing a scientific review and explain the significance of
review articles in research work.
24. What is chemometrics and its significance in research
25. Explain computational methods with examples
26. If an author has 25 publications in which 10 are cited 2 times each, 1 is cited for
240 times, 2 are cited 50 time, 2 are cited 180 times, 5 are cited 20 times and 5 are
cited for 5 times each. What is the average citation? What is i-10 index? What is
the h-index of the author? Explain.
27. Write a note on scifinder and scopus
28. What is citation index and describe i10 and H index
 Short notes

1. Hypothesis testing
2. Literature search engines
3. Molecular mechanics
4. Detection limit
5. Integration algorithms.
6. Research report writing
7. Elaborate the following: Sources of literature
8. Compare between Conference and Workshop
9. Chemometrics.
10. Minimization of error
11. Docking methods in drug design.
12. Writing a research proposal.
13. Tools for assessment of research quality.
14. Cut-off schemes
15. Integration algorithms
16. X-Y Plot
17. Bibliographic Tools
18. Accuracy and precisison
19. Scopus
20. Impact factor
21. CA on CD
22. Research paper
23. standard deviation