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Circulatory System

Histology

Heart
Blood vessels
Lymphatics

BY
Dr Navneet Kumar
Professor Anatomy
KGMU LKO

Dr Navneet Kumar Professor


Anatomy K G M U Lko
Blood vessels
• Deliver nutrients ,removes metabolic products
and exchange of substances
• General structure
1.Tunica intima
2.Tunica media
3.Tunica adventitia

Dr Navneet Kumar Professor


Anatomy K G M U Lko
Blood Vessels
Types (histological)-
• Arteries-Large artery (Elastic artery )
-Medium sized artery (Muscular artery)
-Small artery & Arterioles
- Muscular arterioles
- Terminal arterioles
-Capillaries-Fenestrated
-Continuous
-Discontinuous
• Veins - Large vein
- Medium sized vein
- Venules
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Large artery
• Layers
(1) Tunica intima
• - Endothelium
-Sub endothelial tissue-
Myointimal cells
-Internal elastic lamina- poorly defined
(2)Tunica media
-Thickest layer
- many laminae of elastic fibres
-Few smooth muscle cell & collagen
fibre
outer most- external elastic lamina
(3)Tunica adventitia
• -Fibro elastic tissue
• -Vasa vasorum +nt

Dr Navneet Kumar Professor


Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Large artery

• Examples
• Aorta,
Carotid artery
subclavian
artery

Dr Navneet Kumar Professor


Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Muscular artery
• Layers
• Tunica intima
- Endothelium
-Sub endothelial tissue very less
- internal elastic lamina- very well
defined and wavy
• Tunica media
-Thick layer
- many circular laminae of smooth
muscle fibres
- few elastic fibres & collagen fibre
• Tunica adventitia
-As thick as tunica media
- external elastic lamina
-Fibro elastic tissue (longitudinal)
-Vasa vasorum +nt
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Muscular artery

Dr Navneet Kumar Professor


Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Small artery & Arterioles
• Small artery-Terminal part of
muscular arteries
• 5-6 layer of smooth muscle
• Diameter of wall/lumen ratio is
1:2
• Lumen more than 0.1 mm
• Arterioles- 2-4layer of smooth
muscle cells layers
• Internal elastic lamina absent
• Lumen less than 0.1 mm
• -Muscular arterioles-
100micron to 50 micron
• -Terminal arterioles-50 to
10micron
• Meta arteriols
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
capillary

Dr Navneet Kumar Professor


Anatomy K G M U Lko
Large vein

(1) Tunica intima-


- Endothelium
-Sub Endothelial Tissue
(2) Tunica media-
Very thin, or absent Collagen
fibres
(3) Tunica adventitia-
Thickest ,longitudinal
Smooth muscles, lots of
collagen fibre

Dr Navneet Kumar Professor


Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Medium sized vein

(1) Tunica intima-


- Endothelium
-Sub endothelial tissue
(2) Tunica media-
collagen fibres and
muscle cells circular
layers
(3)Tunica adventitia-
fibro elastic and
connective tissue
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Venule

(1)Tunica intima-
- only Endothelium
(2) Tunica media-
few circular layers muscle
cells
(3)Tunica adventitia-
fibro elastic and connective
tissue

Dr Navneet Kumar Professor


Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko
Dr Navneet Kumar Professor
Anatomy K G M U Lko

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