Common

RIGHT ATRIUM DEVELOPMENT

"RIGHT ATRIUM -’ 3 SOURSE
1.RIGHT HALF OF PRIMITIVE ATRIUM - FROM ROUGH TRABECULATED PART
-IN FRONT CRISTA TERMINALIS
2.ABORPTION OF RIGHT HORN OF SINUS VENOSUs - SMOOTH PART BEGIND CRISTA
TERMINALIS
2 ABORPTION OF RIGHT HALF OF AV CANAL FORM- MOST VENTRAL -’SMOOTH PART

*ABSORPTION OF SINUS VENOUS - CORONARY SINUS & VENA CAVA ARE SEEN
*RIGHT VENOUS VALVE --’BECOME - CRISTA TERMINALIS, INFERIOR VENACAVA
"LEFT VENOUS VALVE --’ FUSED WITH ATRIAL SEPTUM
 DEVELOPMENT OF PANCREAS
*Pancreas Development from - Two buds : Dorsal pancreatic bud
Ventral pancreatic bud
*Ventral bud moves dorsally, lies below the dorsal bud in - 7th week

1.ventral bud - part of head of pancreas + uncinate

2.Dorsal bud- remaining entire pancreas

*PANCREATIC DUCT
dorsal bud & whole of ventral bud
1.Main pancreatic duct derived from distal part of
proximal part of dorsal bud
2.Accessory Pancreatic Duct - derived from -
surrounding mesoderm
*PARENCHYMA DEVELOPS - from
 ROTATION OF MIDGUT
clockwise/anti -clockwise
*During reduction, midgut rotates 3 times, each time by 90° in counter
manner.

1.1st rotation: - Pre arterial segment - right side.

-Post arterial segment - left side.
by
2. 2ND rotation: -Pre arterial segment elongates and enters abdominal cavity and rotates
90° anti-clockwise.
*Pre arterial segment comes to lie behind the superior mesenteric artery.

3.3rd rotation: -Post arterial segment enters abdominal cavity and rotates by 90° anti
clockwise.
 DEVELOPEMNT OF KIDNEY
*Nephrogenic cord - forms
1.At 4th week
---’Kidney.
mesonephric duct &Paramesonephric duct.
pronephros appears, functions as the kidney &
2.By the end of 4th
3.By 5th week - week - mesonephros appears, disappears by end of 4th
as interim Kidney up to a week.
metanephros
4.A diverticulum arises
functions
appear and starts its function by 3r months.
from the mesonephric month.
duct called ureteric bud
which forms
metanephric blastema.
*The kidneys are derived from
1. Excreting two sources:
- Metanephriccomponent - derived from
metanephros.
blastema - contact with ampulla ’ under go
2.
differentiation form nephron
-
Collecting component - derived from ureteric bud.
uretic bud grow toward metanephric blastema > become ampulla
-ampulla -’ form pelvis of kidney - then form minor & major calyx and collecting tubules
*The kidneys become functional from 12th week.
*Ascent of kidney i- Initial in sacral region -> kidney ascend to lumbar region

*Rotation of kidney - Hilum - first anterior, later hilum come medialy

 EMBRYOLOGY

Liver bud
Stomach Hepatic
duct Bile
duct
Cystic
duct
Gallbladder - Dorsal Dorsal pancreas
pancreatic bud
Ventral
pancreatic bud Ventral pancreas
A
Accessory
pancreatic duct
Bile duct

Dorsal Main pancreatic

Minor pancreatic Bile duct duct
papilla duct Uncinate process
Ventral Ventral pancreatic dçct
Major pancreatic
C papilla D
duct
DEVELOPMENT OF PANCREAS

1. Herniation & Elongation & Formati

90° Rotation of Jejunoileal loops

Cecum
Vitelline Superipr
duct
me'senteric a.

Cecal
diverticulum Jejunoileal loops
Umbilical
Cord
Final Positions
Retraction &
180° Rotation

Cecum Stomach

arge
Intstine Large
Jejunoilealloops Cecum Small
Intestine
Intestihe

ROTATION OF MIDGUT
JOHARI MBBS LECTURES 100 DYouTube
 EMBRYOLOGY
Mesonephric a

Metanephric mass
of mesodem
b
Ureteric bud
Remnant of pronephros

Renal pevis
Mesoneph ros

Major cala
Ureter
Developing liver
Minor cala

Nephrogenic cord Renal peNS

Coaca Mesonephric duct Meeenchymal

cellcluser
Metanephnc Melanephric mass
dvertcuum or of sntermedate meS0derm
Metanephris mes
ureternc bud
of mesodem

Groove between lkbw

Pamordium of melanephros (permanent kidney)

Arched colecting tubule Stmight

collecting
tubule
DEVELOPEMNT OF KIDNEY
 3r--’ Common cár
Neural plate border
Neural plate
artery
4th -Arch of aorta

Epidems
NEURAL CREST DERIVATIVES
Convergence
Neural fold
1.Neuron out side CNS
2.Dorsal root of ganglion Neural groove

3.Sensory ganglion of cranial nerve 5th,7th ,10

4.5ympathetic &parasympathetic neuron and ganglion Epidermis

5.Neuroglia of PNS---’ satellite cell

Neural crest

-Neural tube