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SomnoSuite™
Small Animal Anesthesia System
Owner’s Manual
October, 2012
SomnoSuite
Owner's
Manual
©
2012
Kent
Scientific
Corporation,
Documentation
Version
2.10.09,
For
On-‐Unit
Help
Version
2.10.09
and
Firmware
Rev
2.10
Table
of
Contents
Part 1: SomnoSuite User's Guide
Included Equipment – 1
The SomnoSuite Parameters – 2
Getting Started – 3
Controller User Interface – 5
SomnoSuite Configuration – 6
Main Menu – 6
Main Menu > Anesthesia – 6
Main Menu > Air Supply – 8
Main Menu > Minute Vol – 8
Main Menu > MouseVent – 8
Main Menu > MouseSTAT – 14
Main Menu > Actions – 14
Main Menu > History – 16
Main Menu > Alarms – 18
Main Menu > Config – 21
Part 2: Theory of Operation
MouseVent and Artificial Ventilation in Small Animals – 26
MouseSTAT and Pulse Oximetry – 30
Part 3: General Information
Contact Information – 32
Disclaimer – 32
Product Warranty and Satisfaction Guarantee – 32
Cleaning Instructions – 33
Specifications – 33
Additional SomnoSuite Setup – 34
Decontamination Verification Form – 37
This product is not designed, intended or authorized for use in human applications.
Windows
is
a
registered
trademark
of
Microsoft
Corporation
in
the
United
States
and
other
countries.
SomnoSuite,
MouseVent
and
MouseSTAT
are
trademarks
of
Kent
Scientific
Corporation.
Part
1:
SomnoSuite
User's
Guide
The
SomnoSuite
is
an
artificial
ventilation
system
for
use,
with
or
without
anesthesia,
in
small
animals.
It
is
not
designed,
intended
or
authorized
for
use
in
human
applications.
The
SomnoSuite
is
a
digital
vaporizer
that
provides
a
constant-‐flow
stream
of
gas.
It
supports
two
optional
modules:
MouseVent
provides
artificial
ventilation
to
deeply
anesthetized
animals
or
assists
spontaneous
breathing
in
lightly
anesthetized
animals.
Once
you
provide
the
animal's
weight,
the
MouseVent
uses
allometric
formulas
to
automatically
determine
and
use
the
correct
tidal
volume
and
respiration
rate
for
normal
artificial
To
learn
more,
go
to
ventilation.
A
wide
variety
of
settings
allows
you
kentscientific.com
or
to
decide
precisely
how
the
Ventilator
will
work
contact
Kent
Scientific
for
special
procedures.
A
Constant
Flow
state,
about
adding
which
functions
exactly
like
the
Vaporizer
one
or
more
modules
configuration,
is
included.
to
your
existing
SomnoSuite.
MouseSTAT
measures
and
tracks
oxygen
saturation
(SpO2)
heart
rate,
perfusion
and
respiration
rate.
Included Equipment
SomnoSuite MouseVent MouseSTAT
• 1 SomnoSuite • 1 SomnoSuite • 1 pulse Oximeter
Controller with Controller with IDV sensor (variety of
Integrated Digital and MouseVent sensor sizes
Vaporizer (IDV) Module available)
• 1 power supply • 1 MouseVent • 1 sensor adapter
Accessory Kit
• 1 mini USB cable
• 1 packet of 5
• 1 mouse or rat EXP/INSP port filters
induction chamber
• 1 mouse or rat
anesthesia circuit
You will receive only one Controller depending upon whether or not you have purchased the
MouseVent module.
1
The
SomnoSuite
Parameters
The
SomnoSuite
uses
a
variety
of
Parameters
which
appear
in
menus,
displays,
charts,
etc.
The
modules
you
have
installed
and
Modes
of
Operation
the
flow
type
you
use
govern
which
Parameters
are
available
to
The
SomnoSuite
supports
two
you,
and
thus
which
Parameters
appear
in
your
menus.
modes
of
operation:
Parameters In
Run
mode,
the
upper
half
of
the
SomnoSuite screen
displays
the
value
of
one
or
Target percent of anesthesia in gas delivered to the animal more
of
the
Parameters
you
are
% Anest measuring.
The
lower
half
of
the
(user-selectable with Anesthetic Agent Concentration knob)
screen
can
display
charts
of
your
Vol Anest Instantaneous volume of anesthesia remaining in syringe
data,
a
History
of
your
Parameter
VaporTmp Measured temperature of IDV
values
or
your
current
Parameter
Min Vol Measured volume of air delivered to the animal per minute values.
You
can
cycle
through
Pressure Measured pressure of delivered air these
lower-‐half
displays
using
the
Target Minute Volume (= volume of air delivered to the UP
and
DOWN
buttons.
animal per minute) (user-selectable with a default of
Set M Vol In Setup mode, you have access to
100ml/min) This does not appear if you have a MouseVent
module and set it to use the Ventilator. the system menus, which allow
you to configure your SomnoSuite
MouseVent Adds
to meet your requirements. You
PeakPres Highest measured pressure in a cycle
can make settings in a wide variety
Tidal Vol Measured volume of air delivered to the animal per breath of areas, including configuration of
Measured volume of air delivered to the animal per minute the Run-‐mode displays.
Min Vol
(= tidal volume X respiration rate)
Animal's rate of breathing (automatically calculated from
RR Important
animal's weight or user-selectable)
Stopping the Ventilator
Target Inspiration Pressure used when Priority is set to
TargPres Even in Setup mode, the Ventilator
Pressure (user-selectable with a default of 15cmH2O)
continues to run in the
Peak end expiratory pressure (user-selectable with a default
PEEP background. To stop it, press
of 0cmH2O)
RUN/BACK until you get to get the
Instantaneous pressure reflecting the airway pressure of the
Pressure Run screen. Press it one more time
animal
to stop the Ventilator. The lack of
MouseSTAT Adds valve or pump sound will confirm
HR Measured heart rate that it is stopped
SpO2 Measured blood oxygen saturation
Perfusion Measured blood flow at the sensor site To cause the Ventilator to be off
Meas RR Measured respiration rate when you power the Controller on,
go to MouseVent > Advanced >
Run/Stop and choose Stopped. Press
If you purchase a MouseVent module, the Pressure and Min Vol
the RUN/BACK button and then
items remain in your menus, but the definitions of these two items
power off and on.
change.
2
Getting
Started
Three
steps
are
required
to
prepare
your
SomnoSuite
for
use:
Step
1:
Set
up
the
hardware
(instructions
below).
Important
Step
2:
Configure
the
SomnoSuite
using
the
menus.
See
pages
6
and
following.
Step
3,
connecting
the
animal,
should
be
the
last
step
in
your
Step
3:
Connect
the
animal
to
the
SomnoSuite.
See
pages
4
setup.
Be
sure
to
make
all
the
and
following.
settings
and
adjustments
you
can
When
you
have
completed
the
three
steps,
you
will
be
ready
for
before
you
connect
the
animal.
Run
mode,
which
is
the
way
you
will
use
the
SomnoSuite
to
perform
its
tasks.
You
can
always
return
to
the
Menus
from
Run
mode
to
change
your
configuration
parameters.
Step
1:
Set
Up
the
Hardware
Note
about
Connections
For
a
reliable
connection
at
a
Follow
these
directions
to
begin
using
your
SomnoSuite.
Controller
socket—AUX
or
Remote—
you
must
push
the
plug
firmly
until
1. Connect
the
Controller
to
the
power
supply
at
the
it
is
seated
against
the
silver
metal
Controller
Power
socket.
of
the
socket.
2. Plug
the
power
supply
into
a
standard
wall
outlet.
3. Follow the detailed setup directions on page 34.
4. If you have the MouseSTAT module, plug the pulse
oximeter sensor into the sensor adapter cable and then
MouseSTAT Module
plug the sensor adapter cable into the Controller AUX
See page 30 for additional setup
socket.
considerations.
Step 2: Configure the SomnoSuite
Turn the Controller on using the switch on back. When the Home
Screen appears on the Controller, you will see a message: Press The Home Screen
RUN/BACK or SET UP. Press SET UP to display the Main Menu and If you have the MouseVent
configure your SomnoSuite features. module, the Home Screen displays
some important information about
Detailed directions for all the Menu choices begin on page 6. You the setup for the Ventilator along
can also press the Help button on your Controller to see context-‐ with the animal weight you have
sensitive help at any time. selected. You can also change the
animal weight at this screen. See
After you have finished configuring your SomnoSuite, connect the page 9 for more information about
animal to the Ventilator or Vaporizer. Then press RUN/BACK on the animal weight.
Controller to begin running the Ventilator or Vaporizer. This is
called Run mode.
3
Step
3:
Position
and
Connect
the
Animal
Some
instructions
differ
for
the
Ventilator
or
Vaporizer:
1. Turn
the
SomnoSuite
on
and
enter
the
animal’s
weight
Tubing
Diameter
(Ventilator)
or
press
SET UP
and
at
the
Main Menu
and
choose
Neither
the
size
nor
the
length
of
Minute Vol
to
set
your
desired
rate
(Vaporizer).
the
inspiratory
tubing
is
extremely
2. Intubate
the
animal
with
the
appropriate
endotracheal
tube
critical.
On
the
other
hand,
the
or
cannula
(Ventilator).
expiratory
tubing
diameter
should
3. Connect
the
INSP
and
EXP
tubing
from
the
SomnoSuite
to
be
large
enough
to
decrease
any
the
T
or
Y
fitting
on
the
endotracheal
tube
(Ventilator)
or
to
resistance
to
the
expiratory
the
supply/exhaust
port
fittings
on
the
nosecone
(Vaporizer)
airflow.
Since
the
animal
The
connecting
tubing
pieces
should
each
be
about
0.5m
completely
controls
expiration,
long.
higher
expiratory
airway
resistance
4. Place
the
anesthetized
animal
in
the
nosecone.
(Vaporizer)
makes
exhalation
more
difficult.
If
the
animal
fails
to
exhale
5. Adjust
any
settings
as
needed
while
the
system
is
in
Setup
mode.
completely,
it
can
rebreathe
the
same
air,
causing
a
buildup
of
CO2
Important:
If
you
are
not
connecting
any
tubing,
such
as
tubing
for
in
the
lower
airways.
compressed
gas
or
scavenging
canisters,
to
the
ports
on
the
back
of
the
Ventilator,
the
ports
should
be
uncapped
and
open
during
the
use
of
the
Ventilator
or
Vaporizer.
Tip:
While
the
Ventilator
or
About
Connecting
to
the
Animal
Vaporizer
is
running,
prevent
You
can
connect
the
animal
in
several
different
ways
and
many
particulate
contaminants
from
the
researchers
have
their
own
procedures.
One
method
is
to
select
animal
entering
the
tubing
inside
semi
rigid
plastic
tubing,
a
hypodermic
needle
or
an
the
Controller
by
connecting
the
endotracheal
tube
of
the
proper
outside
diameter
and
fit
the
included
filters
to
the EXP
port
on
animal’s
trachea.
You
can
ventilate
the
animal
either
by
the
front
of
the
Controller.
intubation
(through
the
mouth)
or
by
cannulation
(tracheotomy).
Connect
the
endotracheal
tube
to
a
Y
or
T
fitting
as
close
to
the
animal
as
possible
to
minimize
rebreathing
dead
Deadspace
space.
Connect
the
expiratory
and
inspiratory
tubing
lines
to
the
Before
you
connect
the
animal,
arms
of
the
Y
or
T
fitting.
calibrate
the
dead
space.
First,
choose
the
source
of
air
for
your
For
constant
pressure
ventilation,
the
Ventilator
delivers
enough
animal
at
Main Menu>Air Supply.
inspiratory
gases
to
attain
the
desired
pressure.
The
overall
Then,
select
Calib Ddspc at
volume
of
gases
delivered
is
dependent
on
tubing
dead
space
Main>Actions.
Seal
the
end
of
the
and
animal
tidal
volume.
In
other
words,
the
inspiratory
volume
endotracheal
tube
with
your
finger
delivered
is
dynamic
to
maintain
the
desired
inspiratory
airway
or
air
tight
cap
and
press
Select
pressure.
The
correct
tidal
volume
is
delivered
automatically.
twice.
The
MouseVent
will
pressurize
the
respiratory
tubing
circuit
and
calculate
the
dead
For
the
MouseSTAT
space.
The
dead
space
value
will
Apply
the
pulse
oximeter
sensor
to
the
most
convenient
be
subtracted
from
the
total
appendage
of
your
small
animal.
See
page
30
and
following
for
volume
to
give
an
accurate
Tidal
important
information
about
sensors.
Volume
value.
4
Controller
User
Interface
The
SomnoSuite
Buttons
You
communicate
with
the
SomnoSuite
Controller
through
the
buttons
on
the
front
panel.
The
panel
contains
six
buttons
whose
The
Power
Up
Screen
function
depends
on
where
you
are
when
you
press
them:
The
Power
Up
Screen
appears
immediately
as
you
power
up.
It
Home
Screen
Tells
the
SomnoSuite
to
begin
running
lists
the
modules
in
the
unit,
the
RUN
Setup
mode
Goes
back
one
menu
level
BACK serial
number
of
the
unit,
and
the
Run
Mode
Toggles
air
flow
on
and
off
versions
of
the
firmware
and
of
the
Help.
Home
screen
Takes
you
to
the
Main Menu
UP
SET Setup
mode
Scrolls
to
the
next
menu
choice
Run
mode
Turns
off
alarms
and
displays
the Main
Menu
The
Home
Screen
The
Home
Screen
appears
shortly
Setup
mode
Displays
the
sub-‐menu,
if
any,
after
you
power
up.
It
is
a
short
cut
SELECT
associated
with
the
currently
for
quickly
setting
ventilation
highlighted
menu
choice
parameters.
To
return
to
the
Home
Screen
at
any
time,
power
the
Setup
mode
Moves
up
or
down
through
setting
Controller
off
and
then
on
again.
Δ
choices
You
can
view
the
non-‐context-‐
Run
mode
Moves
between
Chart,
History
and
sensitive
sections
of
this
Owner's
Parameters
displays
Manual
on
the
Controller
by
∇
Help
Screens
Pages
forward
or
back
for
multi-‐page
pressing
Help
from
the
Home
help
Screen.
Note
Home
Screen
Toggles
the
general
Help
on
and
off
For
some
menu
choices,
you
will
be
HELP Setup
mode
Toggles
context-‐sensitive
Help
on
and
prompted
to
use
the
SET UP
button
off
for
particular
menu-‐associated
General
Help
Goes
back
one
level
functions.
Menu
Tips
The
menus
displayed
on
the
Controller
screen
allow
you
to
Tip:
When
you
are
using
Help,
configure
the
SomnoSuite
to
meet
your
needs.
Here
are
a
few
check
for
a
prompt
at
the
bottom
general
facts
about
how
the
menus
work:
of
the
screen
indicating
that
the
• As
you
use
the
SET UP
button
to
cycle
through
menu
Help
section
is
continued.
If
you
choices,
the
current
menu
item
becomes
highlighted
in
red.
see
it,
press
the
DOWN
button
to
continue
reading.
• If
the
highlighted
menu
choice
permits
a
direct
action,
such
as
setting
a
value
range
or
clearing
the
History,
you
will
see
instructions
for
that
action
on
the
right.
• If
the
highlighted
menu
choice
leads
to
a
sub-‐menu,
you
will
see
instructions
to
press
SELECT
for
the
new
menu.
• Pressing
the
RUN/BACK
button
at
any
point
within
a
menu
goes
back
one
menu
level.
5
SomnoSuite
Configuration
The
Main
Menu
Any
time
you
press
SET UP
at
the
Home
Screen,
the
Main
Menu
Main
Menu
appears
on
the
left
side
of
the
display.
The
Air On/Off choice
will
be
Air On/Off
highlighted.
Anesthesia
Air Supply
Press
SET UP
to
move
through
the
choices
of
the
Main Menu.
You
will
Minute Vol
see
instructions
on
the
screen
for
each
choice
telling
you
to
either
MouseVent
press
SELECT
for
another
menu
or
use
the
UP
and
DOWN
arrows
to
MouseSTAT
Actions
make
a
setting.
History
Pressing RUN/BACK
moves
back
a
level
in
the
menu
structure.
Alarms
Config
Pressing
RUN/BACK
at
the Main Menu
puts
the
SomnoSuite
into
Run
The
Minute Vol
choice
of
the
Main
mode.
Menu
appears
only
if
you
either
have
no
MouseVent
module
or
if
Main
Menu
>
Air
On/Off
you
have
one
and
are
running
it
Turn
air
flow
ON
with
Air Supply set
to
Constant Flow.
Cycle
between
turning
the
air
flow
ON (choose YES)
or
OFF (choose
NO)
using
UP
and
DOWN.
The
MouseVent choice
of
the
Main
Menu
appears
only
if
you
are
have
If
you
choose NO
for OFF,
pressing
RUN/BACK
will
cause
the
system
a
MouseVent
module
and
have
Air
to
enter
Run
mode
and
all
the
associated
displays
to
appear.
Supply
set
to
Ventilator.
However,
you
will
have
to
press
RUN/BACK
again
if
you
want
the
Ventilator
or
Vaporizer
to
turn
on.
Anesthesia
Menu
Enable
If
you
choose YES
for ON,
the
Ventilator
or
Vaporizer
will
continue
Remove
running
even
if
the
system
is
in
Setup
mode.
This
allows
you
to
Prime tube
make
changes
in
your
system
settings
while
maintaining
an
air
flow
Setup
to
the
animal.
Be
sure
to
configure
the
anesthesia
Main
Menu
>
Anesthesia
component
of
the
system
by
The
Anesthesia
Menu
choosing
Setup
first,
before
you
The
Anesthesia
menu
lets
you
set
up
how
and
if
you
will
use
make
any
other
selections
from
anesthesia
along
with
the
air
flow
to
the
animal:
this
menu.
Anethesia
Menu
>
Enable
Choose
whether
or
not
anesthesia
will
be
included
along
with
the
air
delivered
to
the
animal.
Choices
are
YES
and
NO.
The
default
is
NO.
Before
you
select
YES,
be
sure
your
anesthetic
setup
is
complete,
the
syringe
is
loaded
and
the
anesthesia
tubing
is
filled
and
primed.
6
Anesthesia
Menu
>
Remove
Move
the
pusher
block
away
to
allow
you
to
replace
a
syringe.
Begin
by
removing
the
empty
syringe.
Then
press
SELECT
to
move
the
pusher
block
a
sufficient
distance
to
allow
you
to
place
the
newly
filled
syringe.
The
block
will
stop
6cm
back
from
the
empty
position
you
have
set
with
Main>Anesthesia>Setup>Set Empty.
If
you
want
to
stop
or
restart
the
block,
press
SELECT.
Anesthesia
Menu
>
Prime
tube
Move
the
pusher
block
back
into
position
after
placing
a
newly
filled
Anest
Setup
Menu
syringe.
Press
DOWN
to
adjust
the
position
of
the
block
until
you
Type Anest
have
filled
the
anesthetic
connecting
tubing
with
anesthetic.
Syr Size
Set Empty
Anesthesia
Menu
>
Setup
Vapor Tmp
The
Anest Setup Menu
allows
you
to
select
some
parameters
for
the
anesthesia
delivery
system:
Syringe
Size
Type anest — Choose
the
type
of
anesthetic
you
will
use
in
the
The
SomnoSuite
is
designed
to
use
a
syringe.
Choices
are Isoflurane,
Desflurane
and
Sevoflurane
.
The
standard
gas
tight
analytical
syringe
default
is
Isoflurane.
with
a
6-‐cm
scale.
Syr size — Choose
the
size
of
the
syringe
you
will
be
using. Set
Empty
Refer
to
Chart
1
on
page
34
to
select
the
syringe
size
that
will
Be
sure
to
select
a
plunger
position
provide
anesthesia
for
the
length
of
time
you
want
to
use
it. that
leaves
at
least
a
minute
space
To
ensure
continuous
operation
of
the
pump
and
constant
between
the
plunger
and
the
flow
of
anesthetic,
choose
a
syringe
that
will
last
for
your
syringe
end.
This
eliminates
the
risk
of
pushing
the
plunger
too
hard
into
specific
procedure,
but
no
longer
than
3
to
6
hours.
If
your
the
syringe
and
breaking
it.
If
you
procedure
is
longer
than
that,
fill
a
second
syringe
and
quickly
overshoot
the
empty
position
while
switch
syringes
when
the
first
syringe
is
95%
empty.
See
you
are
setting
it,
back
up
beyond
Main>Actions>Alarm
to
set
an
alarm
that
will
alert
you
when
the
the
empty
position
before
you
syringe
is
almost
empty.
Choices
are
0.1ml,
0.25ml,
0.5ml, 1ml,
continue.
Always
set
the
empty
2ml,
5ml
and
10ml.
The
default
is
2ml.
position
moving
in
the
direction
of
pushing
the
plunger
in.
Set Empty —
Identify
the
position
at
which
the
pusher
block
will
stop
and
treat
the
syringe
as
empty.
With
an
empty
Vapor
Tmp
syringe
in
place, press
UP
or
DOWN
to
move
the
block
to
the
The
IDV
keeps
the
vaporization
area
empty
position
for
the
syringe.
When
you
have
the
plunger
in
at
a
constant
temperature,
which
the
correct
location,
press
SELECT.
The
pusher
block
will
now
you
select
with
Vapor Tmp,
to
provide
automatically
detect
this
position
as
empty
and
stop
moving.
consistent
vaporization
regardless
of
temperature
changes
in
the
Vapor Tmp — Choose
the
temperature
at
which
the
Vaporizer
environment.
Vapor
temperatures:
should
run
to
help
evaporate
the
anesthetic.
Choices
are
isoflurane
=
48°C,
sevoflurane
=
58°C,
desflurane
=
24°C.
values
between
25.0°C
and
50.0°C
in
units
of
1°C,
and OFF.
OFF
turns
the
evaporator
off. The
default
is
40.0°C.
7
Main
Menu
>
Air
Supply
Select
air
supply
Choose
the
source
of
the
air
supply
for
your
animal.
SomnoSuite
Configuration
You
have
two
choices
for
the
Vaporizer
configuration:
The
Vaporizer
configuration
• Internal Pump — Set
the
source
of
air
to
be
the
SomnoSuite
produces
a
constant
flow
stream
pump.
This
is
the
default.
of
air
or
gas
through
an
induction
chamber
or
mask.
The
Ventilator
• Compressed Gas — Set
the
source
of
air
or
gas
to
be
an
configuration,
which
requires
the
external
supply.
MouseVent
module,
functions
as
a
full-‐featured
Ventilator
using
the
You
have
four
choices
for
the
Ventilator
configuration:
MouseVent
functions.
A
Constant
• Ventilator: Internal Pump — Set
the
source
of
air
to
be
the
Flow
operation
is
a
settable
SomnoSuite
pump
and
use
the
Ventilator.
This
is
the
default.
option.
• Ventilator: Compressed Gas — Set
the
source
of
air
or
gas
to
be
an
external
supply
and
use
the
Ventilator.
Using
Compressed
Gas
• Constant Flow: Internal Pump — Set
the
source
of
air
to
be
the
You
can
connect
a
compressed
gas
SomnoSuite
pump
and
use
Constant Flow.
source
such
as
oxygen
or
a
gas
• Constant Flow: Compressed Gas — Set
the
source
of
air
or
gas
to
mixture
to
the
port
on
the
back
of
the
SomnoSuite.
Set
the
gas
be
an
external
supply
and
use
Constant Flow.
pressure
to
be
5psi
(.35kg/cm2
or
35kPa)
but
no
higher
than
10psi
Main
Menu
>
Minute
Vol
(0.7
kg/cm2
or
70kPa)
before
Set
target
flow
rate
connecting
the
tubing
from
the
Choose
the
gas
flow
rate
you
would
like
the
SomnoSuite
to
use.
tank.
This
menu
choice
appears
only
if
you
are
using:
• the
Vaporizer
configuration
of
the
SomnoSuite
The
MouseVent choice
of
the
Main
• the
Ventilator
configuration
with
Air Supply
set
to
Constant menu
appears
only
if
you
have
the
Flow: Internal Pump
or
Constant Flow: Compressed Gas
MouseVent
module
and
have
set
Air Supply
set
to Ventilator.
Choices
range
from
10ml/min
to
500ml/min
in
1ml/min
increments,
allowing
you
to
use
flow
rates
that
are
much
lower
than
traditional
vaporizers
support.
The
default
is
100ml/min.
Main
Menu
>
MouseVent
MouseVent
Menu
Body Wgt
The
MouseVent
Menu
RR
The
MouseVent Menu
allows
you
to
specify
the
operating
conditions
Priority
for
the
MouseVent
Ventilator.
The
number
of
menu
choices
varies
-TargPres
with
the
setting
you
make
under
Priority:
-Tidal Vol
-Init Press
-Max Press
• Inspiration Pressure
(default
setting
for
Priority) — only
-Min Press
TargPres
appears
below
Priority
in
the
MouseVent Menu
PEEP
Advanced
• Tidal
Volume — Tidal Vol, Init Press,
Max Press
and Min Press
appear
instead
8
MouseVent
Menu
>
Body
Wgt
The
Set
body
weight
screen
Choose
the
animal
body
weight
that
will
be
used
to
set
a
typical
RR
and
Tidal Vol for
that
weight.
You
can
choose
a
weight
between
3
and
500g.
The
default
is
30g.
Menu
Choices
As
you
change
the
weight
for
your
animal,
the
default
Tidal Your
choice
under
Priority
Volume,
RR
and
Minute Volume
for
that
weight
are
shown
on
the
determines
whether
a
single
screen.
If
you
want
to
use
values
other
than
these
default
values,
choice—TargPres—or
a
group
of
choices—Tidal Vol, Init Press,
Max
you
must
reset
them
after
you
set
Body Wgt:
Press and
Min Press—will
appear
in
your
menu.
• To
reset
RR,
choose
RR
from
the
MouseVent Menu.
• To
reset Tidal Vol
(and
thus
Minute Vol),
choose
Tidal Vol
under
the Priority
choice
of
the MouseVent
Menu
and
then
set
the
target
Tidal Vol.
See
Priority
below.
Changing
Body
Weight
You
can
also
change
body
weight
Each
time
you
set
a
new
body
weight,
the
defaults
for
that
weight
at
the
Home
Screen
when
you
have
will
appear,
and
those
values
will
replace
any
settings
you
may
the
MouseVent
module.
Setting
have
made
for
them.
the
weight
in
either
place
overrides
any
setting
you
have
previously
MouseVent
Menu
>
RR
made.
Note
that
the
Home
Screen
The
Set
ventilation
rate
screen
also
displays
the
current
settings
Choose
a
target
ventilation
rate
in
breaths
per
minute.
Choices
for
several
important
ventilator
range
from
20
to
350bpm.
The
default
is
133bpm
for
an
animal
of
parameters.
the
default
weight,
which
is
30g.
MouseVent
Menu
>
Priority
The
Set
ventilator
priority
screen
Note
Choose
which
Parameter
will
be
given
priority
as
the
MouseVent
You
will
need
to
calibrate
the
dead
regulates
artificial
ventilation.
You
can
choose
to
ventilate
to
a
space
in
the
connecting
tubing
for
target
Tidal
Vol
or
a
target
inspiration
pressure,
TargPres.
The
the
Ventilator
to
calculate
the
recommended
setting
and
default
is
TargPres.
correct
tidal
volume.
See
page
15.
Your
choice
at
this
screen,
which
depends
upon
the
requirements
of
your
procedure,
will
add
the
selection(s)
you
need
to
the
MouseVent Menu,
allowing
you
to
set
your
target
criteria.
For
more
about
constant-‐volume
ventilation
and
constant-‐pressure
ventilation,
see
pages
26
and
following.
9
MouseVent
Menu
>
TargPres
The
Set
target
insp
pressure
screen
Choose
a
target
inspiration
pressure
that
the
MouseVent
will
try
Tidal
Volume
Priority
to
maintain
from
breath
to
breath.
Choices
range
from
2
to
If
you
choose
Tidal Vol
under
Priority,
the
MouseVent
will
adjust
the
30cmH2O.
The
default
is
15cmH2O.
inspiration
pressure
to
deliver
a
fixed
volume
to
the
animal's
lungs,
This
choice
appears
only
if
you
have
chosen
Inspiration
TargPres
acting
like
a
standard
volume
under
Priority.
ventilator.
The
process
begins
at
the
pressure
you
specify
with Init
MouseVent
Menu
>
Tidal
Vol
Press. If
the
tidal
volume
at
that
The
Set
target
tidal
volume
screen
pressure
does
not
meet
your
Choose
a
target
tidal
volume
that
the
MouseVent
will
try
to
target,
the
MouseVent
adjusts
the
pressure
trying
to
reach
your
maintain
from
breath
to
breath.
Choices
range
from
0.01
to
target
tidal
volume.
5.00ml.
The
default
depends
upon
the
body
weight
you
have
selected.
For
animal
safety,
the
allowed
range
of
pressures
is
bracketed
by
This
choice
appears
only
if
you
have
chosen Tidal Vol
under
Priority.
the
values
you
specify
with
Max
Press and
Min Press.
If
the
MouseVent
Menu
>
Init
Press
MouseVent
reaches
Max Press
before
delivering
your
target
tidal
The
Set
init
insp
pressure
screen
volume,
it
will
stop
inspiration
at
Choose
an
initial
inspiration
pressure
that
the
MouseVent
will
use
Max Press to
avoid
over-‐pressuring
on
its
first
cycle
after
you
press
RUN/BACK.
Choices
range
from
2
the
animal’s
lungs.
If
it
reaches
Min
to
30cmH2O.
The
default
is
15cmH2O.
Press before
delivering
your
target
tidal
volume,
it
will
deliver
Min
This
choice
appears
only
if
you
have
chosen
Tidal Vol
under
Priority.
Press
to
make
sure
the
animal
is
at
least
minimally
ventilated.
MouseVent
Menu
>
Max
Press
IMPORTANT:
If
this
occurs,
check
The
Set
maximum
insp
press
screen
your
settings
and
tubing
Choose
the
maximum
inspiration
pressure
that
the
MouseVent
connections.
should
use
in
trying
to
reach
your
target
tidal
volume.
Choices
Inspiration
Pressure
range
from
the
value
you
have
set
for
Init
Press
to
30cmH2O.
The
Priority
default
is 20cmH2O.
If
you
choose TargPres under
Priority,
the
MouseVent
will
adjust
This
choice
appears
only
if
you
have
chosen Tidal Vol
under
Priority.
the
inspiratory
volume
to
maintain
the
maximum
airway
pressure
at
the
level
you
specify.
See
the
PEEP
choice
of
the
MouseVent
menu
for
open
chest
procedures.
For
more
about
Priority
in
Ventilation,
see
pages
26
and
following.
10
MouseVent
Menu
>
Min
Press
The
Set
minimum
insp
press
screen
Choose
a
minimum
inspiration
pressure
that
the
MouseVent
should
use
in
trying
to
reach
your
target
tidal
volume.
If
the
MouseVent
reaches
the
target
tidal
volume
before
it
reaches
this
minimum
pressure,
it
will
use
the
Min Press
value
to
ensure
that
the
animal
is
at
least
minimally
ventilated.
Choices
range
from
2cmH2O
to
the Init Press
value
you
have
set.
The
default
is
5cmH2O.
This
choice
appears
only
if
you
have
chosen
Tidal Vol
under
Priority.
MouseVent
Menu
>
PEEP
Choose
a
PEEP—Peak
End
Expiratory
Pressure—to
be
used
to
prevent
lung
collapse
in
your
animal.
Choices
range
from
0
to
9cmH2O.
The
default
is
0cmH2O.
For
more
about
PEEP,
see
page
27.
Advanced
Menu
MouseVent
Menu
>
Advanced
Run/Stop
The
Advanced
Menu
I/E Ratio
The
Advanced
Menu
allows
you
to
customize
certain
specialized
Sigh
parameters
of
the
MouseVent.
It
contains
six
choices:
Assist
Triggers
Insp Pause
Run/Stop — Choose
whether
or
not
the
Ventilator
will
run
when
you
turn
the
power
on.
Your
choices
are
Running
or
Stopped.
About
I/E
Ratio
Note
that
you
are
setting
the
ratio
If
you
choose
Stopped,
you
will
have
to
press
RUN/BACK
after
between
the
inspiratory
and
expiratory
phases
of
a
MouseVent
power-‐up
to
cause
the
Ventilator
to
run.
The
default
is
breath
cycle,
not
between
the
Stopped.
inspiratory
phase
and
the
entire
breath
cycle.
That
means
a
ratio
of
Stopping
the
Ventilator
1/2
yields
an
expiratory
phase
that
Even
in
Setup
mode,
the
Ventilator
continues
to
run
in
the
is
twice
as
long
as
the
inspiratory.
background.
To
stop
it,
press
RUN/BACK until
you
reach
the
If
you
wanted
the
inspiratory
cycle
to
be
half
of
an
entire
cycle,
you
Run
screen.
Press
it
one
more
time
to
stop
the
Ventilator.
would
choose
an
I/E Ratio
of 1/1.
The
lack
of
valve
or
pump
sound
will
confirm
that
it
is
stopped.
I/E Ratio — Choose
the
ratio
between
the
inspiratory
and
expiratory
phases
of
a
breath
cycle.
Your
choices
are
1/1,
1/1.5,
1/2,
1/3,
1/4,
and
1/5.
The
default
is 1/2.
11
Sigh — This
choice
leads
to
the
Sigh Menu
which
lets
you
enable
or
disable
Sigh
breaths
and
configure
the
details
of
those
breaths.
The
Sigh Menu
has
three
choices:
Sigh
Menu
• Enable — Choose
to
enable
or
disable
Sigh
breaths.
The
Enable
choices
are
YES
and
NO.
The
default
is
NO.
Sigh Press
Interval
• Sigh Press — Set
the
target
pressure
for
Sigh
breaths.
Choices
range
from
either
TargPres for
Pressure
Priority
or
See
page
29
for
more
about
Sigh
Init Press for
Tidal
Vol
Priority
to
30cmH2O.
The
default
is
breaths.
20cmH2O.
Assist
Menu
• Interval — Set
the
Sigh
breath
interval
by
specifying
the
Enable
number
of
regular
breaths
between
Sigh
breaths.
The
Backup Trg
range
of
choices
is
10
to
100.
The
default
is 25,
meaning
Button Trg
every
26th
breath
will
be
a
Sigh
breath. Remote Trg
Breath Trg
-Trig Press
Assist — This
choice
leads
to
the
Assist Menu
which
allows
you
to
enable
or
disable
assisted
ventilation
and
configure
the
way
in
which
it
will
be
implemented.
The
Assist Menu
Tip:
If
you
have
enabled
assisted
has
six
possible
choices:
breaths
and
have
not
chosen
any
other
trigger,
the
backup
trigger
• Enable — Enable
or
disable
assisted
ventilation.
The
will
be
the
only
trigger
for
an
choices
are
YES
and
NO.
The
default
is
NO.
assisted
breath.
• Backup Trg — Set
the
timed
backup
trigger,
which
acts
as
a
Remote
Triggering
backup
to
any
other
triggers
you
have
set
for
assisted
You
can
apply
an
external
signal
at
ventilation.
The
choices
are
Off
and
a
number
of
cycles
the
REMOTE
connector
of
the
MouseVent
and
use
this
signal
to
between
0.25
and
4.00.
The
MouseVent
will
wait
for
up
trigger
and/or
control
sigh
to
that
number
of
cycle
periods
after
the
end
of
a
cycle,
breaths,
assisted
breathing
and
and
if
no
other
trigger
occurs
in
that
time,
an
assisted
breathing
pauses.
Grounding
pin
5
breath
will
be
delivered.
The
default
is
Off.
of
the
REMOTE port
causes
a
drop
from
high
to
low
and
acts
as
a
• Button Trg — Enable
or
disable
the
SELECT
button
as
a
trigger.
For
continuous
actions,
trigger
for
an
assisted
breath.
If
you
choose
to
enable
it,
such
as
maintaining
Hold at
pressing
SELECT
at
any
time
in
Run
mode
will
cause
an
Expiratory (see
page
13)
the
action
assisted
breath
to
be
delivered.
The
choices
are
YES
and
remains
as
long
as
the
drop
to
low
is
held.
NO.
The
default
is
NO.
You
will
need
a
custom
cable
for
• Remote Trg — Enable
or
disable
the
triggering
of
an
the
REMOTE
connector
if
you
want
assisted
breath
by
an
external
signal
you
supply.
If
Remote to
use
the
Remote
Trigger
feature.
Trg
is
enabled,
a
drop
from
HI
signal
to
LO
on
pin
5
of
the
Contact
Kent
Scientific
for
more
Remote
connector
will
act
as
the
trigger.
The
choices
are
information.
YES
and
NO.
The
default
is
NO.
12
• Breath Trg — Enable
or
disable
the
attempted
breath
trigger,
which
is
the
triggering
of
an
assisted
breath
by
the
animal's
attempt
to
breathe.
Choices
are
YES
and
NO.
The
default
is
NO. If
you
enable
the
breath
trigger,
you
must
set
a
value
for
Trig
Press.
• Trig Press — Select
the
required
drop
in
pressure
that
the
MouseVent
must
detect
before
it
triggers
an
assisted
breath.
Choices
range
from
-‐2.0
to
-‐0.2cmH2O.
The
default
is -0.5cmH2O.
This
menu
choice
appears
only
if
you
have
enabled
the
attempted
breath
trigger
using
the
Breath Trg
choice
of
the
Assist menu.
Triggers — This
choice
leads
to
the Triggers Menu
which
Triggers
Menu
lets
you
choose
the
effect
of
the
SELECT
button
and
Effect
of
the
external
signal
if
you
are
not
already
using
them
-Duration
for
assisted
breathing.
The
Triggers Menu
has
three
-Pressure
possible
choices:
There
may
be
no
choices,
one
choice,
or
two
choices
under Effect
• Effect — Use
UP
and
DOWN
to
choose
the
effect
of
the
depending
on
the
setting
you
make
SELECT
button
and
of
the
external
signal
in
Run
mode.
there.
The
screen
will
read Choose action for triggers
and
will
indicate
which
triggers
are
still
available
for
use.
The
pair
of
Triggers—the
SELECT
button
and
the
external
signal—
The
function
choices
are:
will
both
be
assigned
the
same
o Hold at expiratory — causes
a
pause
at
the
expiratory
function
if
they
are
both
available
phase
until
the
setting
you
make
under
Duration
is
for
assignment.
If
you
have
already
satisfied.
Note
that
when
you
choose
Hold at used
the
SELECT
button,
the
expiratory,
the Duration
choice
is
added
to
the
menu. external
signal
or
both
for
assisted
breathing,
the
used
trigger(s)
will
o Hold at inspiratory — causes
a
pause
at
the
inspiratory
be
marked
as
not
available
for
phase
until
the
settings
you
make
under
Duration
and
Pressure
are
satisfied.
Note
that
when
you
choose selection
here.
Hold at inspiratory,
the
Duration
and
Pressure
choices
are
added
to
the
menu.
o Insert Sigh breath — causes
the
next
breath
after
the
About
Hold
at
Inspiratory
trigger
to
be
a
Sigh
breath. During
a
triggered
pause
in
the
o None — assigns
no
function
to
the
available
triggers.
inspiratory
phase,
the
gas
used
to
The
default
is
None.
maintain
the
pressure
is
not
included
in
the
measured
tidal
volume
for
that
breath.
• Duration — Choose
how
long
a
triggered
pause
will
remain
in
effect.
Choices
are
Until released
or
a
number
of
seconds
between
1
and
30.
Until released
maintains
the
pause
until
you
release
the
SELECT
button
or
the
signal
on
pin
5
of
13
the
Remote
connector
drops
to
low.
The
default
is
Until
released.
• Pressure — Choose
whether
or
not
the
MouseVent
is
to
actively
maintain
a
constant
pressure
during
a
triggered
pause
in
the
inspiratory
cycle,
and
if
so,
what
that
pressure
should
be.
Choices
are
a
pressure
ranging
from
2cmH2O
to
30cmH2O,
or
NOT ACTIVELY HELD.
The
default
is
NOT ACTIVELY HELD.
Insp Pause — Set
the
length
of
the
inspiratory
pause
at
the
end
of
an
active
inspiration.
You
are
choosing
the
length
of
the
pause
as
a
percentage
of
the
time
from
the
opening
of
the
INSP
valve
to
the
opening
of
the
EXP
valve.
Note
that
larger
Insp Pause
values
cause
more
rapid
pressure
changes
in
the
lungs,
with
the
lungs
being
held
for
longer
periods
at
either
TargPress
or
the
tidal
volume.
Choices
range
from
5%
to
50%.
The
default
is
10%.
If
you
do
not
have
the
MouseSTAT
Pulse
Oximeter,
the
screen
will
Main
Menu
>
MouseSTAT
read
Module not installed
and
you
The
Set
minimum
allowed
HR
screen
will
not
be
able
to
set
a
heart
rate.
Choose
a
minimum
heart
rate
for
the
MouseSTAT
module
to
recognize.
This
allows
you
to
filter
out
any
small
movements
or
If
you
do
have
the
MouseSTAT
respiration
artifacts
the
animal
might
produce.
module,
be
sure
to
plug
the
sensor
into
the
Controller
for
the
Select
a
minimum
heart
rate
that
is
higher
than
the
animal's
functions
to
work
properly.
maximum
respiration
rate.
Your
choices
are:
Mouse
(240),
Rat
(140)
To
use
the
Pulse
Oximeter
feature,
and
Custom,
which
can
range
from
40
to
600.
All
heart
rates
are
in
you
must
first
apply
the
pulse
beats
per
minute.
The
default
is
Mouse.
oximeter
sensor
to
a
convenient
appendage
of
your
small
animal.
Read
about
sensors
on
page
30.
Main
Menu
>
Actions
The
Actions
Menu
Tip:
For
best
results,
use
the
hind
The
Actions Menu
allows
you
to
perform
several
"housekeeping"
paw
for
SpO2
measurements.
functions
for
your
SomnoSuite.
It
contains
up
to
five
choices
if
you
have
the
MouseVent
module
and
only
one
choice—Defaults—if
you
Actions
Menu
Purge
are
using
the
Vaporizer
configuration.
Leak Test
Calib Ddspc
Calib Vol
Defaults
14
Actions
Menu
>
Purge
Clear
any
accumulations
from
the
valves
using
high-‐pressure
air
flow.
1. Remove
the
animal
from
the
Ventilator.
2. Using
the
tubing
from
your
MouseVent
Accessory
Kit,
connect
the
INSP
and
EXP
ports.
3. Press
SELECT.
After
you
press
SELECT
the
first
time,
you
will
be
asked
Are you
sure?
Press
SELECT
again
for
Yes
or
SET UP
for
No.
Leak
Test
Actions
Menu
>
Leak
test
The
ventilator
tubing
will
be
Check
for
MouseVent
system
leaks.
pressurized
to
20cmH2O
with
the
1. Remove
the
animal
from
the
Ventilator.
EXP
valve
closed.
The
INSP
valve
2. Firmly
seal
the
end
of
the
endotracheal
tubing
with
your
will
then
be
closed
and
the
finger
or
a
cap
to
test
the
external
tubing.
For
an
internal
pressure
in
the
tubing
will
be
measured
after
two
seconds
has
leak
test,
connect
the
INSP
and
EXP
ports
with
a
short
passed.
You
will
see
a
display
of
length
of
tubing
and
fittings
from
the
accessory
kit.
the
pressure
changes.
The
tubing
3. Press
SELECT.
pressure
drops
must
be
2cmH2O
or
4. You
will
be
asked
Are you sure?
Press
SELECT
again
for
Yes
less
to
pass
the
test.
or
SET UP
for
No.
Calib
Ddspc
Actions
Menu
>
Calib
Ddspc
During
the
test,
try
not
to
flex
the
Calibrate
the
volume
of
all
the
tubing
connected
to
the
tubing
or
move
it
or
the
syringe
to
Ventilator—the
deadspace.
avoid
creating
pressure
1. Ensure
that
all
tubing
is
set
up
exactly
as
you
plan
to
use
it
fluctuations.
to
ventilate
your
animal.
When
the
calibration
is
done,
the
2. Remove
the
animal
from
the
Ventilator.
measured
tube
volume
will
be
3. Firmly
seal
the
end
of
the
endotracheal
tubing
with
your
displayed.
You
do
not
need
to
finger
or
a
cap,
ensuring
that
there
is
no
leakage.
know
this
volume
to
use
the
4. Remove
the
caps
from
the
Air Inlet
and
Exhaust
ports.
MouseVent,
but
a
value
that
looks
5. Press
SELECT.
significantly
off
could
indicate
a
6. You
will
be
asked
Are you sure?
Press
SELECT
again
for
Yes
or
leak
in
the
MouseVent.
SET UP
for
No.
Be
sure
to
perform
this
calibration
every
time
you
modify
your
setup
in
a
way
that
changes
the
kind
or
amount
of
tubing
you
are
using.
Note,
if
you
use
only
a
small
amount
of
tubing
or
large
tidal
volumes,
you
can
ignore
this
procedure.
15
Actions
Menu
>
Calib
Vol
Calibrate
the
volume
registration
components
of
the
MouseVent.
1. Remove
the
animal
from
the
Ventilator.
2. Connect
the
3ml
Volume
Calibration
Syringe
to
the
luer
T.
3. Connect
one
end
of
the
luer
T
to
the
EXP
port
and
one
end
to
the
extension
tubing.
Calib
Vol
4. Connect
the
extension
tubing
to
the
INSP
port.
The
volume
registration
5. Draw
3ml
of
air
into
the
syringe.
components
have
been
calibrated
at
the
factory.
It
is
unlikely
that
6. Press
SELECT.
You
will
be
asked
Are you sure?
Press
SELECT
you
will
need
to
perform
this
again
for
Yes
or
SET UP
for
No.
calibration
unless
you
are
7. Wait
for
the
beep
and
inject
the
3ml
of
air.
experiencing
difficulties
and
a
8. Press
RUN/BACK.
support
representative
at
Kent
Scientific
has
suggested
you
do
so.
This
process
is
different
from
calibrating
the
tubing,
which
corrects
the
tidal
volume
actually
delivered
to
the
animal.
During
During
the
test,
try
not
to
flex
the
the
test,
try
not
to
flex
the
tubing
or
move
it
or
the
syringe
to
tubing
or
move
it
or
the
syringe
to
avoid
creating
pressure
fluctuations.
avoid
creating
pressure
fluctuations.
Actions
Menu
>
Defaults
Restore
all
the
factory
default
settings
for
the
SomnoSuite
Controller.
Press
SELECT. You
will
be
asked
Are you sure?
Press
SELECT
again
for
Yes
or
SET UP
for
No.
If
you
choose
YES,
the
SomnoSuite
will
reset
and
restore
factory
defaults
across
the
entire
unit.
History
Menu
Main
Menu
>
History
Enable
The
History
Menu
Group ID
The
History
Menu
allows
you
to
configure
the
display
of
View
SomnoSuite
historical
data,
and
to
view
the
data
while
you
are
in
SendNew
Menu
mode
in
addition
to
viewing
it
in
Run
mode.
SendAll
Header
The
History
consists
of
stored
data
records
from
your
SomnoSuite
Params
Timing
runs.
The
most
recent
1000
records
are
stored
in
memory
and
are
EraseAll
not
erased
when
the
power
is
turned
off.
You
can
view
the
History
CRC
in
three
ways:
View
History
in
Run
Mode
• in
Menu
mode,
with
the
History>View
(see
page
17)
In
Run
mode,
press
UP
and
DOWN
• in
Run
mode,
on
the
bottom
of
the
screen
to
scroll
through
the
various
• on
your
computer,
by
uploading
the
History
to
your
runtime
displays
until
you
reach
computer
(see
page
17)
the
History.
16
The
History
Menu
contains
ten
choices:
Enable —
Enable
or
disable
the
storage
of
your
History
data.
View
Choices
are
YES
and
NO.
When
you
view
the
History
in
Menu
mode,
you
see
more
Group ID —
Specify
an
optional
six-‐character
identifier
to
be
information
than
you
would
on
the
stored
with
each
record.
If
you
do
not
choose
one,
the
area
Run
screen.
The
first
column
reserved
for
displaying
the
identifier
will
be
blank.
Use
UP
displays
a
unique
identifier
(RecID)
and
DOWN
to
cycle
through
the
choices
for
each
of
the
six
for
each
record.
This
identifier
is
an
automatic
record
counter
and
is
places
in
the
identifier.
Choices
are
letters
from
A
to
Z,
cumulative
until
you
reset
it
with
numerals
from
0
to
9,
underline
(
_
)
and
blank.
Press
the
EraseAll
menu
choice.
Directly
SELECT
after
each
choice
to
move
to
the
next
field
in
the
under
RecID
is
the
time
between
identifier.
Press
SET UP
when
you
finish.
record
uploads.
You
will
also
see
the
Group ID
you
have
specified.
A
View —
View
the
History
on
the
screen.
When
you
select
period
(.)
in
front
of
the
Group ID
this,
the
Menu
will
be
cleared
from
the
screen
and
the
indicates
it
is
consecutive
with
the
History
data
will
appear.
Use
UP
and
DOWN
to
page
previous
record.
An
exclamation
vertically
and
SELECT
to
page
horizontally,
necessary
only
if
point
(!)
indicates
there
are
you
have
more
than
three
parameters
in
a
record.
Press
intervening
records
that
are
not
SET UP
to
return
to
the
menu.
displayed.
This
means
there
was
a
power
off
or
an
interruption
in
saving
(Enable was
set
to
NO)
SendNew —
Send
all
History
records
since
your
last
History
between
records.
upload
to
your
computer
as
ASCII
records.
You
will
be
asked
Are you sure?
before
the
upload
begins.
Press
SELECT
for
YES
and
SET UP
for
NO.
When
the
upload
is
finished,
all
Your
Controller
must
be
connected
to
a
computer
for
SendNew or
uploaded
records
will
be
marked
as
no
longer
new
and
you
SendAll to
work.
No
warning
or
will
see
Upload complete.
Note:
This
action
temporarily
turns
message
is
displayed
if
there
is
no
off
any
regular
data
upload
to
your
computer.
See
page
23.
connection.
When
you
return
to
Run
mode,
your
ordinary
upload
will
resume.
SendAll —
Send
all
History
records
to
your
computer
as
ASCII
records.
This
choice
works
exactly
like
SendNew
above,
except
for
the
fact
that
all
records
are
uploaded.
Header —
Choose
whether
or
not
to
send
a
two-‐line
header
with
each
data
upload.
The
first
line
of
the
Header
contains
the
Parameter
name
of
each
data
column.
The
second
line
contains
the
units
for
each
column,
except
for
column
1,
which
contains
the
time
interval
between
records.
Choices
are
YES
and
NO.
17
Params —
The
Parameters
Menu
lets
you
select
which
Parameters
will
be
stored
and
displayed
in
the
History.
The
modules you have installed determines which Parameters Parameters Menu
appear in your Parameters Menu. % Anest
Vol Anest
Press SET UP to highlight the Parameter whose VaporTmp
display you would like to configure and then use UP and PeakPres
DOWN to choose a column for that Parameter. You may Tidal Vol
Min Vol
select up to ten columns. Your SomnoSuite configuration
RR
determines the default settings. TargPres
PEEP
Timing — Select a History update rate between once every Pressure
second and once every 5 hours. The default setting is 5sec. Set M Vol
SpO2
HR
EraseAll — Clear all History data from memory and reset
Perfusion
RecID to 0. You will be asked Are you sure? Press SELECT for Meas RR
yes and SET UP for no.
CAUTION!
CRC — Specify whether or not to include a CRC check with When you change your Parameter
uploaded History records. If you choose to use a CRC check, selection or Timing, all History data
a four-‐hex-‐digit CRC value will be appended to the end of will be erased! RecID will be reset
each record. It is a standard CRC-‐16rev, calculated from all to 0 as well.
the characters that precede it in the upload frame. The seed
About History Parameters
is 0xFFFF.
The Run-‐mode History display
contains only the first five
columns you specify. Assigning
Main Menu > Alarms no Parameter to a column leaves
The Alarms Menu that column blank.
The Alarms Menu allows you configure how, when and if to use the
SomnoSuite alarms. It contains five choices:
Alarms Menu
Alarm #1
Alarm #1 — The Alarm #1 Menu lets you choose the Alarm #2
circumstance under which Alarm #1, a single-‐beep alarm, will Alarm #3
sound. The Alarm #1 Menu contains five choices: Alarm #4
Sys Alarm
• Parameter — Choose which Parameter you would like
to activate Alarm #1. The available Parameters will
depend upon the modules you have installed. See
page 2. The Omit choice disables the alarm.
18
• Type — Choose the type of circumstance that will
activate Alarm #1. You can choose between activating
the alarm when your measured value is greater than a
threshold value or when it is less than a threshold value. Alarm #1 Menu
Parameter
• Value — Choose the threshold value of the Parameter Type
that will activate Alarm #1. Value
Delay
Allowed Value Ranges Repeat
Parameter Min to Max
PeakPres 0 to 40cmH20 Alarms function only in Run mode.
Alarm conditions are tested once
Tidal Vol 0 to 6ml
per second, so an event that lasts
Min Vol 0 to 1000ml/min under one second could be missed.
RR 0 to 350bpm
TargPres 0 to 30cmH2O
PEEP 0 to 9cmH2O You can reset an alarm in one of
Pressure 0 to 30cmH2O two ways:
Set M Vol 0 to 1000ml/min • Pressing SET UP while you are in
% Anest 0 to 5% Run mode turns off any alarms
Vol Anest 0 to 10ml and resets all alarms to their
Vapor Tmp 0 to 60C initial states.
Meas RR 20 to 350bpm • A momentary press of the
RUN/BACK button performs a
SpO2 70 to 100%
silencing reset. The effect of a
Heart Rate 0 to 900bpm
silencing reset depends on the
0 to 16% or
Perfusion Repeat setting of an alarm. For
0 to 120mmHg
While triggered and Forever, a
Meas RR 20 to 350bpm
silencing reset prevents a re-‐
triggering of the alarm for 60
• Delay — Choose how long the measured value must seconds. For Once per minute, it
meet your alarm trigger value before Alarm #1 sounds. resets the one-‐minute timer.
The minimum value is 0sec and the maximum is 8hr. And for Once per reset, it rearms
the alarm.
Tip: It is a good idea to set an
alarm to warn you when the
volume of anesthesia in the syringe
is running low. You can do this by
configuring an Alarm to sound
when Vol Anest, the amount of
anesthetic left in the syringe,
reaches something like 5 or 10%.
19
• Repeat — Choose
how
long
Alarm #1
will
sound.
The
choices
are:
o Forever — continues
sounding
until
a
reset
as
Multiple
Alarms
described
below
If more than one alarm sounds, the
o While triggered — continues sounding until the beep patterns adjust. For one
trigger condition is no longer met alarm, the beep spacing is 2
seconds. When two or more
o Once per minute — sounds once every minute alarms sound at the same time,
until the trigger condition is no longer met, the spacing decreases to 1 second
although and each alarm sounds in its turn.
For example, if both Alarm #1 and
if the condition recurs, the alarm can sound
Alarm #3 are triggered, the pattern
more often
will be 1 beep, pause, 3 beeps,
o Once per reset — sounds once and not again pause, repeat. Not only does the
until a reset spacing between the alarm
patterns decrease, but the beeps
Alarm #2, Alarm #3 and Alarm #4 — These menus work themselves occur closer together ,
the same way as the Alarm #1 Menu. The number in the causing a clearly noticeable
name of each alarm indicates the number of beeps in change in their sounds.
its beep pattern.
Sys Alarm — Enable or disable the System alarm. The
default is No.
The System alarm is a series of 5 beeps. An error
message on the bottom of the Run screen tells you
the cause of the alarm:
• Lost contact with sensor (sensor is unplugged, loose,
etc.)
• Cannot supply sufficient air
• Oxi sensor failed (with MouseSTAT module only)
• Open to atmosphere
• Delivery tube blocked
• Exhaust tube blocked
• Anesthesia delivery has stopped (reached empty or
stalled)
• Pump communication failed (internal communications
failure)
20
Main
Menu
>
Config
The
Config
Menu
The
Config Menu
allows
you
set
up
data
export
for
use
by
other
programs
and
to
configure
the
display
of
data
on
the
SomnoSuite
Config
Menu
Parameters
Controller
screen.
Chart #1
Chart #2
Some
Config Menu
choices
lead
to
other
menus
that
list
Parameters.
Startup
The
Parameters
that
appear
depend
upon
the
modules
you
have
Upload
installed.
See
page
2.
Analog
Range
The Config Menu
contains
seven
choices:
Parameters
Menu
Parameters — The
Parameters
Menu lets
you
configure
the
% Anest
display
of
your
current
Parameters
on
the
SomnoSuite
Vol Anest
Controller's
Run
screen.
Some
or
all
of
the
Parameters
VaporTmp
shown
in
the
sidebar
appear
in
your
Parameters Menu
PeakPres
depending
upon
your
SomnoSuite
configuration.
Tidal Vol
Min Vol
Press
SET UP
to
highlight
the
Parameter
whose
display
you
RR
TargPres
would
like
to
configure
and
then
use
UP
and
DOWN
to
PEEP
specify
a
location
on
the
screen
for
each
to
be
displayed.
Pressure
Set M Vol
The
screen
locations
look
like
this:
SpO2
HR
1-top 2-top Perfusion
3-top 4-top Meas RR
5-top 6-top
1-bottom 2-bottom
3-bottom 4-bottom
5-bottom 6-bottom
You
may
choose
up
to
twelve
Parameters
to
display.
Font
size
is
adjusted
to
take
advantage
of
the
available
space
on
the
screen.
The
highest-‐numbered
location
you
choose
for
each
half
of
the
screen
(for
example,
3-‐top
is
higher
than
2-‐top)
determines
the
number
of
rows
that
appear
on
that
half
of
the
screen.
21
Chart #1 — The
Chart
#1 Menu
lets
you
configure
the
first
of
two
available
Charts
that
can
be
displayed
on
the
lower
half
of
the
Run
screen
while
your
experiment
is
running.
Press
Chart
Menu
SET UP
to
highlight
the
item
you
would
like
to
set
and
then
Type
use
UP
and
DOWN
to
make
your
setting.
Compose
Timing
For
Type,
select
a
fixed
Parameter
Chart
or
a
customized
Chart
that
uses
your
own
combination
of
Parameters.
You
The Compose choice
will
not
appear
can
select
Omit
if
you
do
not
want
to
display
this
Chart
at
all.
in
the
Chart
Menu
unless
you
first
choose
Composed
under
Chart
Type.
Fixed
Parameter
Charts
graph
your
selected
Parameter(s)
against
time.
The
available
Charts
and
the
default
depend
upon
your
configuration
and
usage
of
the
SomnoSuite.
Charts
The
names
of
most
chart
types
are
self-‐explanatory.
The
The
Chart #1
and
the
Chart #2
exception
is
Oxiwave
for
the
MouseSTAT,
which
is
the
real-‐ choices
of
the Config
Menu
cause
time
infrared
signal
to
help
determine
signal
quality.
same
Chart
Menu
to
be
displayed.
The
only
difference
is
which
of
the
You
can
also
select
your
own
combination
of
Parameters
two
charts
you
will
be
setting
up.
for
your
Chart:
1. Choose
Composed
under
Type.
This
will
cause
the
Compose
choice
to
appear
in
the
menu.
2. Highlight
the
Compose
choice
and
press
SELECT
to
Compose
Menu
go
to
the
Compose
Menu.
% Anest
Vol Anest
3. Highlight
a
Parameter
and
use
UP
and
DOWN
to
VaporTmp
choose
whether
or
not
to
include
that
Parameter
PeakPres
on
your
Chart.
You
may
choose
up
to
three
Tidal Vol
Parameters.
Min Vol
RR
For
Timing,
select
an
update
rate
for
your
data
between
TargPres
10ms
and
10min.
Timing
is
not
adjustable
for
Oxiwave.
PEEP
Pressure
Set M Vol
Choose
the
Parameter
data
range
for
the
Chart
using
the
SpO2
Range Menu.
HR
Perfusion
Chart #2 — This
menu
works
the
same
way
as
the
Pressure
Chart #1
choice.
Meas RR
Timing
22
Startup — Configure
the
Startup
display.
The Startup
display
is
the
one
that
appears
on
the
lower
half
of
the
screen
when
you press RUN/BACK.
Upload Menu
Your choices are Chart #1, Chart #2, History, Parameters or No Enable
Display. The default is Chart #1. Header
Params
This setting determines the initial display only. While you Timing
are in Run mode, you can scroll to other displays with UP CRC
and DOWN.
Upload — The Upload Menu lets you configure the sending of
real-‐time data to your computer through the USB port.
Note that any time you choose to upload History data to
your computer, this data Upload will be suspended
temporarily, and will resume only when you return to Run
mode.
The Upload Menu contains five choices:
• Enable — Enable or disable the upload of your real-‐time
data. Choices are YES and NO.
Parameters Menu
• Header — Choose whether or not to send a two-‐line % Anest
header with each data upload. The first line of the Vol Anest
header contains the Parameter name of each data VaporTmp
PeakPres
column. The second line contains the units for each
Tidal Vol
column, except for column 1, which contains the time
Min Vol
interval between records. Choices are YES and NO. RR
TargPres
• Params — The Parameters Menu lets you select which PEEP
Parameters will be uploaded. The modules you have Pressure
installed determines which Parameters appear in your Set M Vol
Parameters Menu. Press SET UP to highlight the Parameter SpO2
you would like to configure and then use UP and DOWN HR
Perfusion
to choose YES or NO. You may choose up to 20
Meas RR
Parameters. The upload order will match their order in
the menu.
• Timing — Choose a rate between 20ms and 10min. With
the MouseVent, you can also choose End of cycle to
upload data once per breath, however if you make this
choice, keep in mind that the Ventilator must be
running for any data to be uploaded.
23
• CRC –
Specify
whether
or
not
to
include
a
CRC
check
with
uploaded
records.
If
you
choose
to
use
a
CRC
check, a four-‐hex-‐digit CRC value will be appended to
Digital Signature
the end of each record. It is a standard CRC-‐16rev,
For certain applications, such as
calculated from all the characters that precede it in the
GLP or 21CFR Part 11, a digital
upload frame. The seed is 0xFFFF. signature is required for each line
of data. The CRC check, which is a
Note about Uploads check sum of each line of data,
The USB port is configured as a virtual COM port on the provides a unique signature for
computer. Use Windows® Device Manager or a similar each line.
facility on your computer to locate the particular COM port
that is assigned to the Controller.
Data
The COM port settings are 115200 baud, 8 data bits, 1 stop • If you send only one Parameter,
bit, no parity, no flow control. The SomnoSuite Controller each value will be on a single
line.
uses the FTDI USB interface driver. To download the driver,
• If you send multiple
go to www.ftdichip.com/Drivers/VCP.htm. Please contact
Parameters, each set of values
Kent Scientific for recommendations for downloading
will be on a single line with the
terminal emulator software. individual values separated by
spaces.
Analog — The Analog Menu lets you choose which data to
output through the Remote port on the back of the Analog Menu
Controller. Please contact Kent Scientific for the optional % Anest
recorder cable if you would like to use this feature. Vol Anest
VaporTmp
PeakPres
Press SET UP to highlight the Parameter you would like to
Tidal Vol
configure and then use UP and DOWN to choose YES or NO. Min Vol
Your configuration and usage of the SomnoSuite will RR
determine which Parameters appear in your menu. TargPres
PEEP
You may choose only one Parameter for analog output, so Pressure
Set M Vol
setting one to YES automatically sets the others to NO.
SpO2
HR
The data update rate is every 10ms. The voltage output Perfusion
goes from 0V to approximately 4.095V. The endpoints of Pressure
the data range you choose at the Range Menu will Meas RR
correspond to these two voltages.
One D/A signal is available
through the Controller's REMOTE
port. You can use this for analog
recording of a signal from the
Controller—a strip chart, for
example.
24
Range — The
Range
Menu
lets
you
set
the
range
of
data
values
that
will
be
used
to
scale
the
Charts
and
the
analog
output.
Range
Menu
% Anest
Press
SET UP
to
highlight
the
Parameter
you
would
like
to
Vol Anest
configure
and
then
use
UP
and
DOWN
to
make
your
settings.
VaporTmp
The
modules
you
have
installed
determines
which
PeakPres
Tidal Vol
Parameters
appear
in
your
menu.
Some
parameters
have
Min Vol
fixed
ranges,
shown
on
the
chart
below
as
one
(1)
range.
RR
TargPres
Parameter
Ranges
PEEP
Pressure
Parameter # of Ranges Min to Max Set M Vol
% Anest 1 0 to 5% SpO2
Vol Anest 2 0 to 10ml HR
Vapor Tmp 1 25 to 50°C Perfusion
PeakPres 1 0 to 30cmH20
Pressure
Tidal Vol 2 0 to 4ml Meas RR
Min Vol 4 0 to 1000ml/min
RR 3 20 to 350bpm
Setting
a
Range
TargPres 1 0 to 30cmH2O
When
you
set
a
Range
for
a
given
PEEP 1 0 to 10cmH2O Parameter,
the
setting
remains
in
Pressure 1 0 to 30cmH20 force
for
the
Parameter
regardless
SpO2 1 70 to 100% of
where
you
use
it.
In
other
HR 4 0 to 900bpm words,
only
one
Range
of
values
is
Perfusion 2 0 to 16% used
at
a
time
for
a
Parameter,
Meas RR 3 20 to 350bpm and
it
will
be
used
for
Charts
and
for
Analog Output.
For
Charts
When
you
graph
more
than
one
Parameter
on
the
same
Chart,
the
range
must
be
the
same
for
each
Parameter
if
the
Chart
is
to
be
numerically
meaningful.
If
you
choose
two
or
more
different
ranges,
each
Parameter
will
be
scaled
to
fit
the
full
width
of
the
Chart
and
there
will
be
no
labels.
This
would
be
useful
if
you
are
interested
in
a
visual
indication
of
trends
for
your
Parameters
and
are
not
concerned
about
the
actual
numerical
values
in
the
Chart.
For
Analog
Output
The
range
you
specify
for
each
Parameter
scales
the
output
by
assigning
the
low
end
of
your
range
to
0
volts
and
the
high
end
of
your
range
to
4.095
volts.
25
Part
2:
Theory
of
Operation
This
section
provides
some
useful
information
about
the
practical
application
of
the
SomnoSuite
and
its
modules.
MouseVent™
and
Artificial
Ventilation
in
Small
Animals
There
are
two
methods
for
controlling
artificial
ventilation:
pressure
controlled
and
volume
controlled.
Your
specific
application
will
determine
which
type
of
ventilation
priority
is
best
suited
for
your
research.
Pressure
Controlled
Ventilation
Pressure
controlled
ventilation
delivers
inspiratory
gases
at
the
onset
of
the
inspiration
portion
of
the
ventilation
cycle.
Gas
delivery
continues
until
the
inspiratory
pressure
reaches
the
desired
threshold.
The
pressure
in
the
airways
and
lungs
is
then
maintained
during
the
inspiratory
pause
until
the
end
of
the
inspiration
portion
of
the
cycle;
there
is
no
gas
flow
during
this
portion
of
the
cycle.
With
pressure
controlled
ventilation,
the
delivered
volume
is
dynamic,
with
the
Ventilator
delivering
the
appropriate
tidal
volume
to
attain
the
desired
airway
pressure.
This
means
that
the
Ventilator
delivers
enough
air
to
the
tubing
and
animal’s
lungs
to
attain
a
desired
pressure
and
then
stops
until
the
next
inspiration
portion
of
the
respiratory
cycle.
It
will
report
the
tidal
volume
delivered.
(For
constant-‐pressure
ventilation,
select
TargPres
(target
pressure)
at
the
Priority
menu,
then
use
UP
&
DOWN
to
choose
a
target
inspiration
pressure
for
the
MouseVent
to
maintain
from
breath
to
breath.)
Generally,
the
pressure
is
set
between
10
and
15
cmH2O
for
all
animals
with
closed
chest
procedures.
For
open
chest
procedures,
you
should
activate
the
PEEP
feature
to
provide
a
back
pressure
preventing
lung
collapse
at
the
end
of
exhaling.
NOTE:
It
is
possible
for
restriction
of
the
animal’s
airway
to
occur.
Observe
the
animal’s
breathing
pattern.
If
the
Ventilator
reaches
pressure
without
a
noticeable
expansion
of
the
animal’s
chest,
it
is
likely
that
the
animal
is
not
getting
an
adequate
inspiratory
volume.
Volume
Controlled
Ventilation
Volume
controlled
ventilation
delivers
a
constant
inspiratory
volume
and
allows
the
inspiratory
pressure
to
vary
dynamically
with
the
tidal
volume
of
the
animal.
Traditional
volume
controlled
ventilation
delivers
inspiratory
gases
for
the
entire
inspiratory
period
of
the
respiratory
cycle.
The
tidal
volume
of
the
animal
plus
the
connecting
tubing
determines
the
final
airway
pressure.
Care
is
required
to
avoid
over-‐pressurizing
the
lungs
with
an
excessive
volume
of
gas.
26
The
Respiratory
Cycle
In
the
expiratory
portion
of
the
respiratory
cycle,
gases
in
the
lungs
are
released
through
the
expiratory
tubing.
The
lungs
should
be
at
atmospheric
pressure
by
the
end
of
that
portion
of
the
cycle.
During
certain
procedures,
such
as
an
open
chest,
Peak
End
Expiratory
Pressure
(PEEP)
is
required
to
prevent
the
lungs
from
collapsing
since
the
intra-‐pleural
pressure
which
normally
keeps
the
lungs
from
collapsing
has
been
removed.
The
inspiratory
portion
is
typically
one
third
of
the
respiratory
cycle
and
the
expiratory
portion
two
thirds.
The
relative
lengths
of
the
portions
can
be
adjusted
to
meet
your
research
needs.
When
you
choose
Tidal Volume
priority,
the
MouseVent
functions
like
a
volume
ventilator,
reporting
the
airway
pressure
generated
to
deliver
the
desired
inspiratory
volume.
For
animal
safety,
a
minimum
pressure
setting
ensures
maintenance
of
a
minimum
airway
pressure
regardless
of
the
volume
delivered,
ventilating
the
animal
at
a
minimal
level.
A
maximum
pressure
setting
protects
the
animal
from
overventilation
by
ensuring
that,
regardless
of
the
inspiratory
volume,
the
airway
pressure
remains
below
the
maximum
pressure
setting.
You
can
set
the
Min Press and
Max Press
(minimum
and
maximum
pressures)
or
you
can
use
the
default
values
of
5cmH20
and
20cmH20.
Normal
Respiratory
Rate
The
allometric
formula
for
Resting
Respiration
Rate
is:
53.5 x (Body Weight in kg)-0.26
Artificial
Ventilation
in
Open-‐Chested
Animals
The
space
between
the
inside
of
the
chest
cavity,
diaphragm,
and
the
outside
of
the
lungs
is
covered
by
the
pleura
and
is
called
the
intra-‐pleural
space.
The
difference
between
the
negative
intra-‐pleural
pressure
and
atmospheric
pressure
keeps
the
lungs
from
collapsing.
Opening
the
chest
causes
the
intra-‐
pleural
pressure
to
become
equal
to
the
atmospheric
pressure,
which
in
turn
can
cause
a
collapse
of
the
lungs.
Because
there
is
no
restriction
on
the
expiratory
cycle
of
the
MouseVent
to
the
exhaust
port
on
the
rear
of
the
Ventilator,
all
the
air
can
escape
from
the
lungs
and
the
lungs
can
collapse.
To
prevent
a
collapsed
lung,
a
PEEP
(Peak
End
Expiratory
Pressure)
is
used.
Even
with
the PEEP
activated,
inflating
collapsed
lungs
can
initially
take
significant
pressure.
Using
a
sigh
breath
set
to
a
pressure
higher
than
the
Target
Pressure
may
help.
Be
sure
to
have
the
PEEP
activated
before
opening
the
chest
cavity
to
avoid
lung
collapse.
Artificial
Ventilation
in
Closed-‐Chested
Animals
The
animal
must
be
sufficiently
anesthetized
to
completely
inhibit
normal
breathing.
If
you
would
like
the
animal
to
breathe
on
its
own,
the
Assist
feature
of
the
Ventilator
must
be
active.
See
page
12
for
additional
details.
If
the
animal
fails
to
breathe
adequately
on
its
own
with
the
Assist
Breath Trg feature
activated,
you
must
set
the
Backup
Trigger
(Backup Trg)
in
the
Assist
mode
or
deactivate
the
Assist
and
use
controlled
artificial
ventilation.
27
About
Anesthesia
and
Anesthetics
Anesthesia
is
the
controllable
and
reversible
loss
of
consciousness
induced
by
chemical
intoxication
of
the
central
nervous
system.
The
goal
of
anesthetic
administration
is
to
prevent
the
perception
of
painful
stimuli
without
undue
depression
of
Anesthesialogical
functions.
Characteristic
features
of
the
anesthetic
state
include
lowered
sensitivity
to
outside
stimuli
(including
pain),
relaxation,
and
diminished
motor
response.
In
general,
the
safest
anesthetics
are
inhalants
used
with
the
proper
delivery
and
scavenging
systems.
The
most
commonly
used
currently
available
inhalant
anesthetics
are
isoflurane,
sevoflurane
and
desflurane.
All
three
have
applications
in
animal
research
due
to
their
rapid
onset
and
offset
with
minimal
side
effects.
They
are
the
currently
recommended
inhalant
anesthetics.
Halogenated ether that is a clear, colorless,
Forane, 1-chloro-2,2,2- volatile liquid at standard temperature and
Isoflurane pressure. It has a mild, ether-like odor and a
trifluoroethyldifluoromethyl ether
molecular weight of 184.5.
Halogenated fully fluorinated methyl isopropyl
2,2,2-trifluoro-1-(trifluoromethyl) ethyl
Sevoflurane ether that is sweet smelling and non-flammable.
ether It has a molecular weight of 200.
Halogenated methyl isopropyl ether that is fast
1,2,2,2-tetrafluoroethyl difluoromethyl
Desflurane acting, pungent, non-flammable. It has a low
ether
vapor temp and a molecular weight of 168.
All
three
of
these
agents
require
a
precision
vaporizer
for
delivery
to
the
animal.
An
induction
chamber
can
be
used
for
mice
or
rats.
Anesthetic
concentrations
from
the
vaporizer
are
typically
limited
to
5
percent.
Since
isoflurane,
sevoflurane
and
desflurane
are
very
rapid-‐acting
inhalant
anesthetics,
death
can
result
if
the
animal
is
not
observed
closely
or
if
the
concentration
is
too
high.
One
advantage
of
these
agents
is
that
they
are
not
metabolized
and
therefore
have
little
or
no
toxic
effect.
Another
is
that
they
are
relatively
insoluble
in
blood,
and
therefore
are
“blown-‐off”
quickly,
providing
a
quick
recovery.
Although
very
similar
to
one
another,
each
of
these
agents
has
slightly
different
effects
and
mechanisms
of
action,
yet
the
anesthetic
result
is
nearly
identical.
For
safety,
waste
gas
scavenging
systems
are
required
when
using
these
agents.
Precision
vaporizers
provide
precise,
controlled
levels
of
anesthesia
administration
to
the
patient,
offering
a
margin
of
safety
for
the
animal.
Using
gas
anesthetics
at
full
concentration
out
of
the
bottle
quickly
results
in
overdosing
the
animal
and
can
kill
very
quickly.
Precision
vaporizers
are
part
of
an
anesthesia
machine
and
serve
to
mix
inspiratory
gases,
such
as
air
or
oxygen,
with
the
anesthetic
in
a
precisely-‐controlled
concentration.
Animal
researchers
who
routinely
incorporate
surgery
or
the
use
of
anesthetics
in
their
animal
experiments
should
consider
purchasing
an
anesthesia
machine.
The
SomnoSuite
is
a
precision
vaporizer
and
artificial
ventilator
for
small
animals
such
as
mice
and
small
rats.
For
other
animals
or
applications,
Kent
Scientific
has
a
selection
of
single-‐
and
multiple-‐channel
complete
anesthesia
systems
to
choose
from,
as
well
as
new
and
remanufactured
vaporizers.
28
Glossary
of
Terms
Target
Pressure
(TargPres):
The
airway
pressure
to
be
attained
by
the
end
of
the
inspiratory
portion
of
the
ventilation
despite
changing
respiratory
mechanics
or
ventilatory
muscle
activity.
Tidal
Volume
(TidalVol):
The
volume
of
gas
either
inhaled
or
exhaled
during
a
breath.
Initial
Inspiratory
Pressure
(Init Press):
The
initial
inspiratory
pressure
used
as
a
starting
point
to
deliver
the
first
breath
when
searching
for
the
set
tidal
volume
with
ventilation
priority
set
to
tidal
volume.
Maximum
Inspiratory
Pressure
(Max Press):
The
maximum
inspiratory
pressure
allowed
during
tidal
volume
priority
ventilation.
This
safety
setting
prevents
over-‐ventilation
of
the
animal
since
inspiratory
gas
delivery
stops
at
Max
Press
even
if
the
Tidal
Vol
has
not
been
attained.
Default
is
20cmH20.
Minimum
Inspiratory
Pressure
(Min Press):
The
minimum
inspiratory
pressure
that
must
be
reached
regardless
of
the
inspiratory
tidal
volume
delivered.
This
safety
setting
ensures
a
minimal
ventilation
level
for
the
animal.
Default
is
5cmH20.
Positive
End
Expiratory
Pressure
(PEEP):
A
minimum
positive
airway
pressure
that
is
maintained
at
the
end
of
the
expiration
during
pulmonary
ventilation
to
prevent
the
lungs
and
alveoli
from
collapsing
completely
between
breaths.
Primarily
used
with
open
chested
applications,
this
setting
mimics
the
negative
intra
pleural
pressure
of
closed
chested
animals.
Minute
Volume
(Min Vol):
The
total
volume
delivered
per
minute
calculated
by
multiplying
the
tidal
volume
by
the
respiratory
rate.
Sigh
Breath
(Sigh):
The
introduction
of
a
typically
larger
than
normal
tidal
volume
that
inflates
the
animal’s
lungs
to
a
larger
volume,
replicating
the
natural
sigh.
This
allows
the
lungs
to
expand
and
open
any
collapsed
alveoli,
redistributing
pulmonary
surfactant
and
preventing
microatelectasis.
Inspiratory
Pause:
The
interval
from
the
end
of
inspiratory
flow
to
the
start
of
expiratory
flow.
Assisted
Ventilation:
A
breath
for
which
a
ventilator
generates
all
or
part
of
the
inspiratory
flow.
The
MouseVent
is
capable
of
generating
an
assisted
breath
based
on
any
of
these
triggering
events:
you
press
the
SELECT
button
(Button Trg)
to
initiate
one
ventilation
cycle
time
between
cycles
reaches
a
user-‐selectable
point
(Backup Trg)
an
external
digital
signal
is
received
(Remote Trg)
the
animal
attempts
to
breathe
(Breath Trg)
Cycle:
One
complete
breath—inspiration
and
expiration.
End
Expiratory
Pressure:
The
pressure
at
the
end
of
the
expiratory
phase
measured
relative
to
atmospheric
pressure.
Expiratory
Pause
(Hold at expiratory):
The
interval
from
the
end
of
expiratory
flow
to
the
start
of
inspiratory
flow.
29
MouseSTAT
and
Pulse
Oximetry
A
pulse
oximeter
measures
how
much
oxygen
is
carried
in
the
blood.
Oxygen
saturation
and
pulse
rate
are
determined
by
passing
two
wavelengths
of
low
intensity
light,
one
red
and
one
infrared,
through
the
body
tissue
to
a
photodetector.
The
signal
strength
of
each
light
source
depends
on
the
color
and
thickness
of
the
body
tissue,
sensor
placement,
and
the
absorption
of
the
arterial
and
venous
blood
in
the
body
tissue.
Oximetry
processes
the
signals,
separating
out
the
time-‐invariant
parameters
(arterial
volume
and
SpO2)
to
identify
the
pulses
and
calculate
the
oxygen
saturation.
Simple
calculations
for
oxygen
saturation
can
be
performed
because
blood
saturated
with
oxygen
predictably
absorbs
less
red
light
than
oxygen-‐depleted
blood.
Since
measurements
of
SpO2
depend
on
a
pulsating
vascular
bed,
any
condition
that
restricts
blood
flow,
such
as
the
use
of
spring-‐loaded
Y-‐clip
sensors,
may
make
accurate
SpO2
and
pulse
rate
readings
impossible.
1
Perfusion
Index
Perfusion
Index
(PI)
is
a
numeric
value
indicating
the
strength
of
the
plethysmographic
signal
at
the
sensor
site.
The
greater
the
number,
the
greater
the
level
of
blood
flow
is
at
the
sensor
site.
The
highest
perfusion
index
value
indicates
the
optimal
site
for
sensor
placement.
Each
perfusion
index
value
is
unique
to
the
sensor
site.
MouseSTAT
Sensors
The
MouseSTAT
Pulse
Oximeter
module
includes
one
pulse
oximeter
sensor
with
each
Controller.
There
are
two
styles
of
MouseSTAT
Sensor:
annular
and
Y-‐clip:
• The
non-‐contact
annular
sensor
allows
for
accurate
measurements
without
making
contact
with
the
skin.
MouseSTAT
sensors
are
available
in
five
sizes:
4mm,
5mm,
7mm,
9mm,
and
13mm.
The
size
refers
to
the
internal
diameter
of
the
hole
in
the
center
of
the
sensor.
For
proper
fit,
measure
the
outer
diameter
of
the
appendage
on
which
you
plan
to
place
the
sensor
and
select
the
sensor
that
is
one
size
up
from
that
diameter.
The
MouseSTAT
annular
sensor
does
not
require
contact
with
the
skin
to
obtain
accurate
measurements.
Applications
for
the
annular
sensor
include
hind
paw
and
front
paw.
• The
Y-‐clip
sensor
is
typically
used
on
thin
portions
of
skin
or
tongue
on
larger
animals
and
is
designed
to
make
contact
with
the
skin
without
affecting
circulation.
The
maximum
spread
is
15mm.
Examples
of
application
sites
for
the
Y-‐clip
sensor
include
the
rat
paw
or
tongue,
dog
toe
web
or
tongue,
etc.
The
Y
clip
will
detect
signals
equally
well
on
the
mouse
front
or
rear
paw,
but
its
size
and
weight
make
it
difficult
to
use
on
the
mouse.
Sensor
Placement
When
possible,
the
measurement
site
should
be
moist.
If
fur
is
present
at
the
site,
slightly
moisten
and
1
Wright,
B.,
Hellyer,
P.W.,
Respiratory
Monitoring
During
Anesthesia:
Pulse
Oximetry
and
Capnography.
30
separate
it
to
expose
as
much
skin
as
possible.
For
best
results,
position
the
sensor
in
an
area
where
there
is
the
least
fur
and
pigment,
such
as
the
palm
(metacarpal
or
metatarsal)
region
of
the
paw.
Paw:
Annular
or
Y-‐Clip
Sensor
We
recommend
the
MouseSTAT
annular
sensor
for
pulse
oximetry
measurements
on
the
metacarpal
or
metatarsal
region
of
the
paw
of
very
small
subjects.
The
hind
paw
is
optimal
because
less
movement
associated
with
breathing
occurs
there
compared
to
the
front
paw.
Use
the
width
of
the
paw
as
your
measurement
and
place
the
annular
sensor
over
the
walking
pads.
When
applying
the
annular
sensor,
rotate
the
sensor
back
and
forth
to
encourage
the
toes
to
come
together
and
slide
through
the
hole
in
the
sensor.
The
toes
should
extend
from
the
sensor
for
optimal
signal
detection.
The
angle
of
the
sensor
is
not
a
major
consideration
in
placing
the
sensor
on
the
paw.
Tail:
Annular
or
Y-‐Clip
Sensor
We
do
not
recommend
the
MouseSTAT
annular
sensor
for
pulse
oximetry
measurements
on
the
tail.
Significant
research
over
the
years
has
shown
the
tail
of
a
rat
or
mouse
to
be
a
specialized
organ
under
control
of
the
CNS
for
the
thermoregulatory
control
of
body
temperature.
Warming
of
the
subject
to
the
point
of
eliciting
a
thermoregulatory
response
is
required
to
increase
blood
flow
through
the
tail
and
assure
the
most
accurate
SpO2
readings.
Experiments
of
Lemons
and
Wu2
have
shown
that:
• perfusion
in
the
tail
tip
is
more
than
tenfold
higher
than
that
in
the
tail
base
• perfusion
in
the
middle
region
of
the
tail
increases
eightfold
during
warming
compared
to
threefold
to
fourfold
in
the
base
and
tip.
Our
experience
shows
that
pulse
oximetry
sensors
placed
simultaneously
on
a
limb
and
the
tail
of
non-‐
warmed
subjects
such
as
rat
pups
and
mice
produce
significant
differences
in
signal
quality.
The
limb,
which
is
a
smaller
appendage,
shows
a
significant
pulse
signal
quite
usable
for
SpO2
detection,
but
the
signal
from
the
base
tail
is
almost
devoid
of
pulses
and
shows
mainly
a
strong
respiration
artifact.
Ear:
Y-‐Clip
Sensor
We
recommend
the
MouseSTAT
Y-‐clip
sensor
for
pulse
oximetry
measurements
on
the
ear
of
larger
animals.
Place
the
Y-‐clip
sensor
on
the
portion
of
the
ear
that
provides
the
greatest
amount
of
skin
surface-‐area
contact
with
the
Y-‐clip
sensor.
Generally,
ear
placement
is
suitable
for
larger
animals
such
as
rabbits,
cats,
dogs,
etc.
where
the
annular
sensor
will
not
fit.
Tongue:
Y-‐Clip
Sensor
We
recommend
the
MouseSTAT
Y-‐clip
sensor
for
pulse
oximetry
measurements
on
the
tongue
of
larger
animals.
Place
the
Y-‐clip
sensor
on
the
portion
of
the
tongue
that
provides
the
greatest
amount
of
skin
surface-‐area
contact
with
the
Y-‐clip
sensor.
Generally,
lingual
placement
is
suitable
for
larger
animals
such
as
rabbits,
cats,
dogs,
etc.
where
the
annular
sensor
will
not
fit.
2
Wu
Y,
Jiji
LM,
Lemons
DE,
Weinbaum
S.,
Department
of
Mechanical
Engineering,
City
College
of
the
City
University
of
New
York,
New
York,
USA.
A
non-‐uniform
three-‐dimensional
perfusion
model
of
rat
tail
heat
transfer.
Phys
Med
Biol.
1995
May;40(5):789-‐806.
31
Part
3:
General
Information
Thank
you
for
purchasing
a
SomnoSuite.
We
truly
appreciate
your
business.
We
strongly
advise
that
you
read
and
study
this
Owner’s
Manual
to
appreciate
fully
all
the
features,
benefits,
and
capabilities
of
the
SomnoSuite.
Contact
Information
Kent
Scientific
Corporation
Toll-‐Free:
888-‐5RATTUS
(888-‐572-‐8887)
1116
Litchfield
Street
Outside
US:
860-‐626-‐1172
Torrington,
Connecticut
06790
Fax:
860-‐626-‐1179
E-‐mail:
sales@kentscientific.com
Internet:
www.kentscientific.com
Disclaimer
Kent
Scientific
Corporation
makes
no
representations
or
warranties,
expressed,
statutory
or
implied,
regarding
the
fitness
or
merchantability
of
the
components
of
this
system
for
any
particular
purpose.
Further,
Kent
Scientific
Corporation
is
not
liable
for
any
damages,
including
but
not
limited
to,
lost
profits,
lost
savings,
or
other
incidental
or
consequential
damages
arising
from
ownership
or
use
of
these
products,
or
for
any
delay
in
the
performance
of
its
obligations
under
the
warranty
due
to
causes
beyond
its
control.
In
no
case
shall
Kent
Scientific
Corporation's
financial
obligation
extend
beyond
the
cost
of
or
replacement
of
the
Kent
product
in
question.
Kent
Scientific
Corporation
also
reserves
the
right
to
make
any
improvements
or
modifications
to
these
products
described
in
this
manual
at
any
time,
without
notice
of
these
changes.
All
brand
and
product
names
used
in
this
manual
are
the
trademarks
of
their
respective
owners.
This
product
is
not
designed,
intended
or
authorized
for
use
in
human
applications.
Product
Warranty
The
SomnoSuite
has
a
one
(1)
year
warranty
including
all
parts
and
labor
charges.
This
warranty
does
not
cover
damage
by
any
cause
including,
but
not
limited
to,
any
malfunction,
defect
or
failure
caused
by
or
resulting
from
unauthorized
service
or
parts,
improper
maintenance,
operation
contrary
to
furn-‐
ished
instructions,
shipping
or
transit
accidents,
modifications
or
repair
by
the
user,
harsh
environments,
misuse,
neglect,
abuse,
accident,
incorrect
line
voltage,
fire,
flood,
other
natural
disasters,
or
normal
wear
and
tear.
Changes
or
modifications
not
approved
by
Kent
Scientific
Corporation
could
void
the
warranty.
The
foregoing
is
in
lieu
of
all
other
expressed
warranties.
Kent
Scientific
Corporation
does
not
assume
or
authorize
any
party
to
assume
for
it
any
other
obligation
or
liability.
Satisfaction
Guarantee
Should
you
experience
difficulty
with
the
SomnoSuite,
our
Technical
Support
Group
will
assist
you
in
trouble-‐shooting
and
determining
if
the
product
needs
to
be
returned
to
our
facility.
We
will
issue
you
a
Return
Manufacturer
Authorization
(RMA)
number
before
the
product
is
shipped
back
for
repair.
It
is
at
the
discretion
of
the
manufacturer
to
replace
or
repair
a
defective
part
or
product.
Please
call
Customer
Service
at
888-‐572-‐8887
to
obtain
a
Return
Manufacturer
Authorization
number.
Shipments
without
a
RMA
number
will
not
be
accepted.
Please
note
that
after
our
30-‐day
return
policy
period
ends,
we
will
be
happy
to
assist
you
with
your
application,
but
cannot
issue
any
credit
or
refund
for
a
returned
SomnoSuite.
Prior
to
shipment,
please
clean
and
decontaminate
the
product
of
any
chemical,
biological,
or
isotopic
contamination.
Please
include
a
completed
Decontamination
Verification
Form
with
the
shipment.
The
form
can
be
found
on
page
37
of
this
Owner's
Manual.
Additional
copies
are
available
by
calling
Kent
Scientific
Customer
Service
at
888-‐572-‐8887.
32
Cleaning
Instructions
Do
not
use
any
alcohol
(except
as
indicated)
or
abrasive
detergents.
Controller:
Always
position
the
Controller
away
from
areas
of
potential
contamination.
Should
the
unit
become
soiled,
gently
spot
clean
with
a
damp
wipe
or
towel.
Never
use
liquids
directly
on
the
Controller.
Airway
Adapter:
Clean
with
a
small
amount
of
soap
and
warm
water.
Allow
to
dry
completely
before
use.
MouseSTAT Pulse Oximeter Sensor: Gently wipe the Sensor clean.
Specifications
Controller
Voltage
12
V,
2.5A
Connection
x1
mini
USB,
x1
power,
x1
6-‐pin
DIN,
x1
8-‐pin
DIN
(x1
5-‐pin
DIN
for
factory
use
only)
Dimensions
29cm
(11.41in)
x
20cm
(7.87in)
x
7.6cm
(2.97in)
Weight
1.7kg;
1.9kg
if
MouseVent
included
Power
Supply
Input
100
to
240
V,
50
to
60
Hz,
1.0
A
Output
12
V,
2.5
A
MouseVent
Control
Modes
Volume
controlled,
pressure
controlled
I:E
Ratio
1:1
to
1:5
PEEP
Built-‐in
Respiratory
Assist
Automatic
or
Manual
Sigh
Pressure
up
to
30
cmH2O
Sigh
Breath
Automatic
or
Manual
Respiratory
Rate
Range
20
to
350BPM
Max
Inspiratory
Flow
1.5SLPM
Weight
Range
<3
to
500gm
MouseSTAT
Heart
Rate
Up
to
900bpm
Resolution
1%
SpO2
Range
70
to
100%
Alarms
5,
programmable
Data
Export
Yes
SpO2
Sensors
Y-‐Clip
and
non-‐contact
annular
paw
sensors
Annular
Paw
Sensors
4mm,
5mm,
7mm,
9mm
and
13mm
33
Additional
SomnoSuite
Setup
Initial
Setup
1. Select
the
syringe
you
will
be
using.
Choose
a
syringe
size
that
will
provide
3
to
6
hours
of
anesthesia
for
the
weight
of
the
animal.
(See
Chart
1
below.)
The
flow
rate
from
the
syringe
is
based
on
the
Minute
Volume
(MV)
of
the
animal’s
respiration
rate
and
%
anesthesia.
An
estimated
value
of
MV
can
be
obtained
using
allometric
formulas
based
on
the
animal’s
weight.
The
chart
below
shows
the
estimated
duration,
as
it
varies
by
body
weight,
of
anesthetic
at
1%
and
2.5%
concentrations
and
for
two
different
syringe
sizes.
To
estimate
duration
for
other
anesthetic
concentrations,
scale
the
duration
values
for
1%
concentration
to
match
the
required
concentration.
Chart
1
Anesthesia
Duration
for
Body
Weight
and
Syringe
Size
9
Hours
of
Anesthesia
Hr
@
1%
8
Isof,
1ml
syringe
per
7
Kg
Hours
of
Anesthesia
6
Hr
@
2.5%
Isof,
1ml
5
syringe
per
Kg
Hours
of
4
Anesthesia
Hr
@
1%
Isof,
2ml
3
syringe
per
Kg
2
Hours
of
Anesthesia
Hr
@
2.5%
1
Isof,
2ml
syringe
per
0
Kg
0 0.1 0.2 0.3 0.4 0.5 0.6
Animal Weight in kg
34
2. Mount
the
empty
syringe
onto
the
SomnoSuite
Controller.
3. Turn
the
SomnoSuite
Controller
on
and
press
SET UP.
When
the
Main
Menu
appears,
press
SET
UP
until
Anesthesia
is
highlighted.
Press
SELECT.
4. At
the
resulting
Anesthesia
menu,
ensure
that
Enable
is
set
to
NO.
If Enable
is
set
to
YES,
press
UP
or
DOWN
to
change
it.
This
will
allow
additional
menu
selections
to
appear.
5. Press the SET UP button until the SETUP menu choice is highlighted. Press SELECT.
6. With Syr Size highlighted, press UP and DOWN to choose your syringe size.
7. Press
the
SET UP
button
until
the
Set Empty
menu
choice
is
highlighted.
Press UP
and
DOWN
to
make
fine
adjustments
to
the
empty
point
of
the
syringe.
See
page
7.
Once
the
plunger
in
the
syringe
is
down
to
the
empty
position,
press
SELECT
to
save
this
empty
point.
The
anesthesia
syringe
pump
is
based
on
the
6
cm
calibrated
range
of
analytical
syringes.
8. The
Vaporizer
heater
may
be
used
to
assist
in
the
vaporization
of
the
anesthetic.
The
vaporization
temperature
of
isoflurane
is
48°C.
Press
the
SET UP button
to
highlight
the
Vapor
Tmp
menu
choice.
Press
UP and
DOWN
to
adjust
the
temperature.
A
good
starting
point
is
35°C.
Allow
approximately
15
minutes
for
the
Vaporizer
to
reach
operational
temperature
before
using.
All
values
of
the
Setup
variables
are
stored
in
non-‐volatile
memory
until
you
change
them.
They
are
retained
when
the
unit
is
powered
down.
Day-‐to-‐Day
Operation
1. Remove
the
syringe
from
the
syringe
pump
and
fill
it
with
anesthetic.
2. Select
Anesthesia
from
the
Main
Menu
(To
get
to
Setup
mode
from
Run
mode,
press
SET UP.)
Press
SET UP,
highlight
Remove
and
press
SELECT.
This
will
move
the
syringe
plunger
block
6cm
to
accept
a
full
syringe.
3. Mount the filled syringe and secure it to the Controller with the syringe barrel clamp.
35
4. Push
the
female
luer
fitting
on
the
anesthetic
supply
tubing
that
is
connected
to
the
Vaporizer
block
onto
the
end
of
the
syringe.
5. Press
Set Up
to
highlight
Prime tube
at
the
Anesthesia
menu
and
briefly
press
DOWN
to
remove
air
in
the
tubing
and
prime
the
system.
The
system
is
primed
when
the
anesthetic
supply
tubing
is
filled.
6. Press
SET UP to
highlight
Enable.
Use
UP or
DOWN
to
choose
YES
and
press
RUN/BACK
to
go
back
to
the
Main
Menu.
7. Set
the
Anesthetic Agent Concentration dial
to
minimum
to
prevent
the
anesthesia
syringe
pump
from
operating
before
it
is
needed.
8. The
Vaporizer
is
now
ready
to
use
with
the
Ventilator.
Follow
the
instructions
on
pages
8
and
following
to
set-‐up
and
run
the
Ventilator.
Once
the
Ventilator
is
running,
use
the
Anesthetic Agent Concentration
dial
to
adjust
the
percentage
of
anesthesia
to
deliver.
9. Optional:
Use
the
MouseVent
Alarm
feature
to
alert
you
to
a
low
volume
level
of
anesthetic
in
the
syringe.
See
page
18.
36
C O R P O R A T I O N
Decontamination Verification Form
RMA #:
Serial #:
Product Code:
Prior to service of equipment that may be contaminated with biohazardous materials,
potentially biohazardous materials, or radioactivity; the user must first decontaminate the
equipment being returned.
Please complete the form below and return to Kent Scientific with your instrument. You may
also fax it to (860) 626-‐1179.
The decontamination procedure will include the following, as appropriate:
This equipment has not been used in a laboratory and/or a location which
would result in any biohazard or radioactive exposure.
This equipment was appropriately decontaminated* from any biohazardous
materials with:
_____________________________________________________________
*Example: Autoclave, 10% bleach, Ethylene Oxide, formalin, etc. (Please note that it is the user’s responsibility to confirm that the
method of decontamination used is appropriate). Instruments must be decontaminated externally and internally, if needed.
This
equipment
was
appropriately
decontaminated
and
tested
for
radioactivity
by:
_____________________________________________________________
3 14
*Example:
Wipe
test
with
results
( H, C, α-emitters), Geiger counts, etc.
Name
(print): Telephone:
Signature: Date:
1116
Litchfield
Street,
Torrington
CT
06790
Toll
Free:
888-‐572-‐8887
Local:
860-‐626-‐1172
Fax:
860-‐626-‐1179
Web:
www.kentscientific.com
37
SomnoSuite Addendum
SomnoSuite Version 2.10 July 12, 2012
SomnoSuite Hook-Up
with MouseVent Automatic Ventilator
F/Air
Canister
Compressed
Gas Supply
Exhaust
Room Air Supply
Expiratory Line
Inspiratory Line
Breathing tube
Animal
SomnoSuite Hook-Up
using a separate ventilator
F/Air
Canister
Compressed
Gas Supply
Room Air Supply
Exhaust
Expiratory Line
Bypass Flow Control
Inspiratory Line
Outlet Inlet
Ventilator
Breathing tube
Exp Insp
Animal
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