Printed on: Fri Jan 05 2024, 10:24:32 PM(EST) Status: Currently Official on 06-Jan-2024 DocId: GUID-F67620F0-3905-4498-9EC8-BCD6F2F017E1_4_en-US

Printed by: USP NF Official Date: Official as of 01-Jun-2023 Document Type: NF @2024 USPC
Do Not Distribute DOI Ref: xb3rn DOI: https://doi.org/10.31003/USPNF_M100_04_01
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Spray-dried Acacia: White to off-white compacted

Acacia microscopic fragments or whole spheres
DEFINITION • MICROBIAL ENUMERATION TESTS á61ñ and TESTS FOR
Acacia is the dried gummy exudate from the stems and SPECIFIED MICROORGANISMS á62ñ: Meets the requirements
branches of Acacia senegal (L.) Willd. or of other related of the tests for absence of Salmonella species
African species of Acacia (Fam. Leguminosae). • WATER DETERMINATION, Method III (Gravimetric) á921ñ
Analysis: For unground Acacia, crush in a mortar until it
IDENTIFICATION passes through a No. 40 sieve, and mix the ground material
• A. before weighing the test specimen. Dry a sample at 105°
Analysis: To 10 mL of a cold solution (1 in 50) add 0.2 mL for 5 h.
of diluted lead subacetate TS. Acceptance criteria: NMT 15.0% of its weight
Acceptance criteria: A flocculent, or curdy, white • ARTICLES OF BOTANICAL ORIGIN, Acid-Insoluble Ash á561ñ:
precipitate is formed immediately. NMT 0.5%
• ARTICLES OF BOTANICAL ORIGIN, Total Ash á561ñ: NMT
IMPURITIES 4.0%
Change to read: • INSOLUBLE RESIDUE
Sample solution: Dissolve 5.0 g of powdered or finely
• ▲ARSENIC á211ñ, Procedures, Procedure 2▲ (CN 1-Jun-2023): NMT ground Acacia in 100 mL of water. Add 10 mL of 3 N
3 ppm hydrochloric acid.
Analysis: Boil the Sample solution gently for 15 min. Pass by
Change to read: suction, while hot, through a tared filtering crucible. Wash
thoroughly with hot water, dry at 105° for 1 h, and weigh.
• ▲LEAD á251ñ, Procedures, Procedure 1▲ (CN 1-Jun-2023): NMT Acceptance criteria: The weight of the residue thus

al
10 ppm obtained does not exceed 50 mg.
• STARCH OR DEXTRIN
SPECIFIC TESTS Sample solution: A solution (1 in 50)
• BOTANIC CHARACTERISTICS Analysis: Boil the Sample solution cool, and add iodine TS.
Acacia: Spheroidal tears up to 32 mm in diameter or in ci Acceptance criteria: No bluish or reddish color is produced.
angular fragments of white to yellowish white color. It is • SOLUBILITY AND REACTION
translucent or somewhat opaque from the presence of Sample: 1 g
numerous minute fissures; very brittle, the fractured surface Analysis: Dissolve the Sample in 2 mL of water.
glassy and occasionally iridescent. It is almost odorless and Acceptance criteria: The resulting solution flows readily
produces a mucilaginous sensation on the tongue. and is acid to litmus.
ffi
Flake Acacia: White to yellowish white, thin flakes, • TANNIN-BEARING GUMS
appearing under the microscope as colorless, striated Sample solution: A solution (1 in 50)
fragments Analysis: To 10 mL of the Sample solution add 0.1 mL of
Powdered Acacia: White to yellowish white, angular ferric chloride TS.
microscopic fragments with only traces of starch or Acceptance criteria: No blackish coloration or blackish
vegetable tissues present precipitate is produced.
O

Granular Acacia: White to pale yellowish white, fine

granules. Under the microscope it appears as colorless, ADDITIONAL REQUIREMENTS
glassy, irregularly angular fragments up to 100 µm in • PACKAGING AND STORAGE: Preserve in tight containers.
thickness, some of which exhibit parallel linear streaks.

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