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  • Cbe 40a HW3

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    Huỳnh Huy Đắc
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    1) The document provides information about mass balances for various units in a pharmaceutical production process. 2) Key values and equations are given for the evaporator, crystallizer, and overall process balances. 3) The question asks to calculate the flow rate of antibiotic solution needed to achieve a certain concentration in the final mixture.

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    CBE 40A HW3

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    1) The document provides information about mass balances for various units in a pharmaceutical production process. 2) Key values and equations are given for the evaporator, crystallizer, and overall process balances. 3) The question asks to calculate the flow rate of antibiotic solution needed to achieve a certain concentration in the final mixture.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    2 views5 pages

    Cbe 40a HW3

    Uploaded by

    Huỳnh Huy Đắc
    1) The document provides information about mass balances for various units in a pharmaceutical production process. 2) Key values and equations are given for the evaporator, crystallizer, and overall process balances. 3) The question asks to calculate the flow rate of antibiotic solution needed to achieve a certain concentration in the final mixture.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 5

    #3 0.

    25%5
    Half
    ##¥%hrad
    ◦¥¥=Ñ ÷Im÷*=
    6

    0.12s 0.25s

    ↓ ,÷a%i%
    "

    b) for overall ballance for recycled ballance


    .mil/dof--0ttunK--Hims)2lg=dofo#indl=2
    # unit:-& Cm ,
    indie # = 2
    for evaporator balance

    }dof=0|
    -

    lmaimq
    )§dof=O
    # unK=2
    # inde =L -

    0.55mL Mz -_

    for
    crystallization balance Mz=%-g
    # link.

    21m¢ end
    __
    = 409 .

    Kats
    # inde -2 -

    m4=m2_ %
    M•=§n=Hmn = 4059 -225
    mF Mj Ms =
    225kg + Mf .
    =
    184kg Is
    0.12M , =
    0.00mg -111 man (0-25)
    0.121225-1%7--11 Mano .25)
    0.121225-111 man) =
    llmsin (0-25)
    msln = 18.88kg Mi6 207.68 Kgb
    =

    Mi 2250-94-1 207.68kg/s= 432.68 Kgb .

    mq-mgtmg-ma-M5-mary-ms.tn
    184=0
    Mary -1 Msh 10.75) +
    Mg(0.75)
    184=0+18.810.757 +
    mg-loit5-mg-226.GE
    ratio :
    mm?-=¥z{¥-g= 0.520 .

    2)
    172,9¥ :*
    -0

    ¥=o
    ?

    µ
    24=0.00 E ÷÷ %¥
    ↓
    0.956.65mg)

    M4
    y , -0.00 yg -0.00 B- =

    €
    ,
    -100 2-5-0.65 g- =0

    0%410.357=0.14 95=0
    .

    2-5=1
    2--4=1-0.6-0.14--0.26 .

    FE-s.ms 0cg ?
    µ
    -
    _

    850 98=0.7
    YEO V 2-8--9 .

    2-6--1
    MG
    Let x=%s 2- = Yow
    y=%I
    '

    UnK=Mi→6iM8iX2iY2iK+iZ7iK8i 2-8=13
    fgdof
    #
    #Independ balance
    09510.67ms)
    }
    • Mit Mz=Mg+M4 • MI -

    •
    M4=M6 -1mg • 92=1 -

    Iz ☒
    •
    My -_M5 My -1 • 7-7=1
    -

    Iz
    2-8=0.3 9cg
    -

    •
    Mg : 1167 Kglh

    Mz= My -1mF
    My -10.95mg) 0.65 -1360kg/h
    Mz= 915kg/h
    mitrinz -_
    ring -1in , =
    915+1167=2082 kglh

    (1) m ,
    + CO )mz-40.657mg -110.261mg
    898
    on
    ,
    =
    Ugh
    Mz -2082-898=1184 Kg1h

    3)
    A- 150mm

    ÷.i⇐¥T→
    ih=0.75m4nin
    ms=?iUz= ?
    %=?iY= ?
    4mg/h
    V3.63

    m⇐
    I

    Zz =
    ?
    =¢mgµ ,

    % 100mm
    yz=l5mglmliZz=?
    Let oe : concentration salt
    y : - antibiotic
    2- :
    _
    +120

    # UMK :
    miimzimzivzivziz-iiizziz-3ix.si 93=10
    # Balance
    Xiv ,
    + Aziz = Isis .

    give -1
    Yz % =
    9303
    Ziv , t 2-282 =
    2-303

    ME Xiii ,
    + esiu , + 2- iv.
    Mz =
    XzV2 +
    Yzvz -12-202
    m
    , ↳↳ +
    •↳ + ↳ balance
    Yjvz 4.0mg/h = .

    '

    M
    ,
    = f ✗ V1
    Me = f ✗ V2
    Mz = $ ✗
    if

    Dof -10-10=0 .

    c) calculate Uzi
    ʳmˢ i "Im ,
    UH +9202
    ,
    =
    YgV3
    ⑥ V1 -165 mg 1mL)Vz= 4.0mg 1h ✗ th
    V2 0.0044 Mamon 60 =

    OGU , +
    RzUz=Ñz
    450 mmdlmixo.75mltm.in) +400 Mmd / mD(0.0044Mumin)
    OGUZ = 112.94 mmol /min
    91min
    112.94mmol
    min
    ✗
    µ↓mmᵈma- 50-5%-1 ✗ = 6.6

    V , +V2 Ug -
    - 0.75 -10.0044 = 0.7544mL /min
    in , f ✗ V1
    =
    =

    19mg 75mL/min =
    75191min
    -750mg 1min
    =

    Miz Sx V2 = =
    1dm, × . 0044mL/ min 0.004491min =

    in -1mi '

    754.4mg/ mid 4.491min =

    , My = =
    ?⃝
    ¥3 ¥÷¢= =
    0.0087

    4m¥ ¥!¥
    = =
    0.000089

    d) since V2 contain
    only antibiotic
    V2 stay the same

    e) yjuz =
    8.0mg In =
    '
    8.0mg In ✗ Moomin 0.133mg / min
    =

    9,4 + Yik Yzug =

    b) G-5h4min) -1 457 V2 = 0.133


    V2 = 0.089 mL/ min

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