CArisk 2.0 CTH Hasil

Name : 203039100013_R12C02
Date of Birth : 06/06/1978

Gender : female
Patient ID : 203039100013_R12C02
Ref ID : R20190301001
Lab ID : 20190301001 JKT
CArisk 2.0
THIS IS YOUR PERSONAL CANCER RISK BASED ON YOUR

GENOMIC INFORMATION
1). In this result you will see some of your genetic risk related to some of the most common types of cancer.
2). On the first pages you will find several explanations regarding the analysis and scope of this test
CANCER RISK : SINGLE NUCLEOTIDE POLYMORPHISMS (SNPs)

In this test we analyze single nucleotide polymorphisms (SNPs). It is important to note that this test does not
sequence the entire genome, we analyze 650,000 SNPs using microarray platform. CArisk is a genomic test that
identify more than 200 variants.
In this test we analyze low penetrance variants of the SNPs in the databases, so there could be mutations in a
region that we can not see in this test (high penetrance).
WHAT IS THIS RESULT BASED ON ?

This test is based on different genetic studies internationally consolidated and accepted by the scientific
community. Our genetic tests are carried out by applying these studies to the genotype of our clients.
GWAS AND RISK SCORING

In this test the risk for certain cancer is calculated with polygenic risk score based on the summary statistics of
genome-wide association study (GWAS) in Asian population. Risk indicator for individual SNP solely to provide
an insight of whether or not you carry risk variant for the particular SNP. It does not indicate the final risk for
certain cancer. Rather, the risk of several SNPs are required to determine the final genetic risk for certain cancer.
DOES IT ALL DEPEND ON MY GENES?

Not at all, our body responds to many conditions. Our genes are certainly an important parameter. Lifestyle,
sport, food, and many other circumstances influence our body.
Knowing yourself certainly helps to treat our body in the most appropriate way. And this is what these genetic
result give you more information about your health.
Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

Date of Birth : 06/06/1978 Lab ID : 20190301001 JKT Test Panel : CArisk 2.0
Patient ID : 203039100013_R12C02
Page 1 of 31
IF THIS RESULT SHOWS THAT I HAVE A GENETIC RISK TO A
SPECIFIC CANCER RISK, AM I GOING TO SUFFER IT FOR
SURE?
Not necessarily. You may have genetic risk to a particular disease and never develop it or you may not have a
risk to a disease and suffer it in the future. Genetic analysis is just one tool for doctors and specialized health
professionals to arrange personal health management.
IF THE RESULT INDICATES THAT I HAVE HIGHER RISK FOR

CERTAIN CANCER, DOES THAT MEAN THAT I HAVE THAT
CANCER FOR SURE?
No, this test is not for diagnostic use. The result of this test show your risk for certain cancer, so you would be
more aware of the risk and gain information on how to take precautions in an appropriate way to minimize the
risk of developing the cancer.
If the result is high, it means that you have high risk to develop certain cancer in the future. But you can prevent it
by avoid some factor that can increase the risk of certain cancers.
On the other hand, this technology has a reliability greater than 99% but there is no 100% reliability in this type of
genotyping technology. If you have any doubt you should talk to your personal doctor or genetic counselor.
IF THE RESULT REFLECTS THAT I HAVE LOW RISK FOR

CERTAIN CANCER, DOES THAT MEAN I AM FREE OF CANCER
FOR SURE?
No, you have to stay alert. Our test does not analyze all the genome region where mutations may exist and we
do not analyze the insertion deletion, or duplication. We analyze only some SNPs so there could be markers in
the other test and we would not be seeing them.
There are diagnostic tests with greater coverage in certain pathologies that are valid for clinical use. If you have
any doubt you should talk to your personal doctor or genetic counselor.

Patient ID : 203039100013_R12C02
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ANALYSIS 1. Non-hodgkin lymphoma
SCOPE 2. Colorectal cancer
3. Gastric cancer
4. Ovarian cancer
5. Liver cancer
6. Bladder cancer
7. Thyroid cancer
8. Pancreatic cancer
9. Lung cancer
10. Nasopharyngeal cancer
11. Breast cancer
12. Cervical cancer
REPORT 1. Key Risks

CONTENT 2. Life style Recommendations
DISEASE High risk : There is an indication of having higher risk than the
average population for the disease
RISK LEVELS
Potential risk : There is an indication of having slightly higher risk than
the average population for the disease
Average risk : There is an indication of having similar risk with the
Low risk : There is an indication of having lower risk than the
Keep in mind that you can not alter your genetic predisposition, however by following the
given recommendation you may improve your protection against or reduce your disease
risk

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RESULT SUMMARY
YOUR The overall results indicates that you are subjected to:
SUMMARY - Cervical cancer
KEY RISKS
LIFE STYLE RECOMMENDATIONS

- Avoid smokers
- Control sexual life
- Control use of birth control pills
- Immunize for HPV
- Perform a cervical a screening
- Quit smoking

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1. Ovarian cancer
Ovarian cancer happened when the cells in the ovary multiply abnormally and form tumor
cells. If left untreated, cancerous tumor cells may spread to other part of the body and this is
known as metastatic ovarian cancer. It is the seventh most common cancer worldwide and
the most common cause of gynaecological-cancer-associated death. Late diagnosis is one of
the factors for much of the stubbornly high mortality and morbidity associated with ovarian
cancer as the earliest symptoms are vague and easy to dismiss. Only 20% of ovarian cancers
are detected at an early stage. Old age, no pregnancy experience and family history of
ovarian cancer may increase the risk of developing ovarian cancer. Screening is highly
recommended in women with a family history of ovarian cancer.
Gene Gene variant Genotype
CASC8 rs6983267 GG
COL15A1 rs1413299 TG
F8 rs7058826 CC
HOTAIR rs4759314 AA
HOTAIR rs7958904 GG
IL-27 kgp5444132 AA
Icb-1 rs1467465 GG
LOC105376496 rs1192691 TG
MLH1 rs1800734 AG
NFKB1 rs28362491 ID
VDR rs2228570.1 GG
Overall Risk Score

According to the test of all above Cancer related gene variants, the overall risk score for
this disease is 0.19. Compared to the overall population, your overall risk is Average
Risk Range
0.19 Low Risk Average Risk Potential Risk High Risk

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Related Factors
Life style - Obesity
- Red meat consumption

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2. Colorectal cancer
Colorectal cancer is due to the abnormal growth of cells that develop from the large intestine.
It is the fourth most common cause of cancer death globally. It is more common in developed
than developing countries. Most colorectal cancers are due to old age and lifestyle factors
with only a small number of cases due to genetic disorders. Some risk factors include diet,
obesity, smoking, and lack of physical activity. Dietary factors that increase the risk include
red and processed meat as well as alcohol. Other risk factors include inflammatory bowel
diseases and less than 5% of cases which are contributed by some inherited genetic
disorders.
BTLA kgp7919985 TC
C5orf66 rs647161 CC
CASC8 rs6983267 GG
CASC8 rs10505477 AA
CASC8 rs10808555 AG
CASC8 rs7014346 AG
CCND2-AS1 rs10774214 TT
FOXF1 rs2178146 TT
FOXQ1 rs9502893 TT
HHEX rs7923837 AA
HSPA12A rs1665650 CC
LOC105369625 rs10849432 TT
LOC105376400 rs10795668 AG
MIR146A rs2910164 GC
MIR196A2 rs11614913 TC
MTOR kgp323129 TT
MYRF rs174537 TG
NR rs744166 GG
NXN rs12603526 TT
RHPN2 rs10411210 CC
SLC22A3 rs7758229 GG
SMAD7 rs4939827 CC
SMAD7 rs7229639 GG

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SYNJ2 rs9365723 AA
TCF7L2 rs11196172 AA
VEGFA rs3025039 CC
VTI1A rs12241008 TT
XRCC1 rs1799782 AG
intergenic rs1800469 AG
intergenic rs11903757 TT
intergenic rs719725 AC
Overall Risk Score

Risk Range
Related Factors
Life style - Inadequate diet
- Lack of physical activity
Possible - Polyposis
disease history

Patient ID : 203039100013_R12C02
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3. Bladder cancer
Bladder cancer is cancer that develops from the cell linings or tissues of the bladder wall. It is
is a highly prevalent disease and is associated with substantial morbidity, mortality and cost.
Environmental or occupational exposures to carcinogens, especially tobacco, are the main
risk factors for bladder cancer. This cancer usually occurs after the age of 40 years and is
seen mostly in people between 50 to 70 years of age. It is about 5 times more common in
men than in women. Usually, bladder cancer is diagnosed when a patient present with blood
in the urine, also called hematuria and further confirmed by doctor sees the tumor through a
cystoscope and during transurethral resection of a bladder tumor (TURBT).
APOBEC3A rs1014971 TC
CLK3 rs11543198 AG
CLPTM1L rs401681 TC
CYP1B1 rs10012 CG
MYC rs9642880 TG
MYNN rs10936599 TT
NAT2 rs1495741 AA
PSCA rs2294008 CC
SLC14A1 rs17674580 CC
TACC3 rs798766 CC
UGT1A rs11892031 AA
intergenic rs710521 TC
Overall Risk Score

Risk Range

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Related Factors

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4. Breast cancer
Breast cancer is due to the abnormal growth of cells that develops from the breast. It is the
most common invasive cancer in women worldwide. It affects about 12% of women
worldwide. The greatest risk factors for breast cancer are being female and older age. Other
risk factors include being female, obesity, lack of physical exercise, drinking alcohol, hormone
replacement therapy during menopause, ionizing radiation, early age at first menstruation,
having children late or not at all, prior history of breast cancer, and family history. About 5% to
10% of cases are due to genes passing down from a person's parents. Signs of breast cancer
may include a lump in the breast, a change in breast shape, dimpling of the skin, fluid coming
from the nipple, a newly inverted nipple, or a red or scaly patch of skin.
ATM rs28904921 TT
BRCA1 rs80357015 GG
BRCA1 rs273898682 AA
BRCA1 rs1799950 TT
BRCA2 rs11571833 AA
BRCA2 rs80359129 GG
BRCA2 rs11571747 AA
BRCA2 rs1799954 CC
BRCA2 rs4987117 CC
BRCA2 rs144848 AA
BRCA2 rs80359077 GG
CASC16 rs3803662 GG
CASC16 rs12922061 CC
CASC16 rs4784227 CC
CCDC170 rs3757318 GG
ESR1 rs2046210 GG
FGFR2 rs2981582 GG
FGFR2 rs3750817 TC
FGFR2 rs1219648 AA
FGFR2 rs2981578 TC
P53 rs1042522 GG
SIAH2 rs6788895 TG

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TERT rs10069690 CC
ZNF365 rs10822013 TC
Overall Risk Score

this disease is -0.59. Compared to the overall population, your overall risk is Low
Risk Range
-0.59 Low Risk Average Risk Potential Risk High Risk
Related Factors
Environment - Ionizing radiation
Life style - Lack of exercise

- Alcohol consumption

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5. Non-hodgkin lymphoma
There is a network of vessels and glands spread throughout human body which known as
lymphatic system. This system is part of human immune system which carry a type of clear
fluid called lymph throughout the body. This fluid contains infection-fighting white blood cells
known as lymphocytes. Non-Hodgkin lymphoma arise when lymphocytes start to divide and
grow abnormally. The affected lymphocytes lose their infection-fighting properties, making a
person more vulnerable to infection. The most common symptom of non-Hodgkin lymphoma
is a painless swelling in a lymph node, usually in the neck, armpit or groin. Conditions such as
weakens immune system (due to medical condition) and exposure to certain viruses
(HIV,Epstein-Barr virus, or Helicobacter pylori) are believe to increase the risk of developing
this cancer.
CXCR5 rs6421571 CC
CXCR5 kgp6811315 AA
FGFR4 rs351855 AG
HLA-DQB1 rs2647012 TC
IL10 rs1800896 TT
IL10 rs1800871 AG
IL2 rs2069762 AA
IRF4 rs872071 AG
LTA rs909253 AG
MDM4 rs4245739 AA
MTHFR rs1801131 TT
MTHFR rs1801133 GG
PVT1 rs13255292 TC
TNF rs1800629 GG
TNFAIP8 rs1045241 TC
TP53 rs1042522 GG
miR-196a2 rs11614913 TC

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Overall Risk Score
Risk Range
Related Factors

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6. Gastric cancer
Gastric cancer, also known as stomach cancer, is cancer developing from the lining of the
stomach. It is the fifth leading cause of cancer and the third leading cause of death from
cancer globally. It occurs most commonly in East Asia and Eastern Europe and occurs twice
as often in males as in females.The most common cause is infection by the bacterium
Helicobacter pylori. Smoking, dietary factors such as pickled vegetables and obesity are other
risk factors. About 10% of cases are due to genetic factors. Early symptoms may include
heartburn, upper abdominal pain, nausea and loss of appetite. Later signs and symptoms
may include weight loss, yellowing of the skin and whites of the eyes, vomiting, difficulty
swallowing and blood in the stool among others.
CASP8 rs3834129 II
DNAH11 rs2285947 GG
FCGR2A rs1801274 AG
IL17A rs2275913 AG
KRT83 rs146753414 CC
LOC284998 rs12615966 CC
MTHFR rs1801133 GG
MUC1 rs2070803 GG
NKAPL rs1679709 GG
PLCE1 rs11187870 GG
PLCE1 rs3781264 AA
PRKAA1 rs13361707 TT
PSCA rs2976392 GG
PSCA rs2294008 CC
PSCA rs138377917 GG
SELE rs5361 TT
TERT rs2736100 AA
TNFA rs1799724 CC
intergenic rs4460629 CC
intergenic rs6983267 GG

Patient ID : 203039100013_R12C02
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Overall Risk Score
this disease is -0.18. Compared to the overall population, your overall risk is Average
Risk Range
-0.18 Low Risk Average Risk Potential Risk High Risk
Related Factors
Environment - Passive smoking
Life style - Inadequate diet

- Obesity
- Stomach ulcer
- Active smoking

Patient ID : 203039100013_R12C02
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7. Thyroid cancer
Thyroid cancer is cancer that develops from the tissues of the thyroid gland. It is a disease in
which cells grow abnormally and have the potential to spread to other parts of the body.
Symptoms can include swelling or a lump in the neck.The prognosis of thyroid cancer is
related to the type of cancer and the stage at the time of diagnosis. For the most common
form of thyroid cancer, papillary, the overall prognosis is favorable.The increased incidence of
papillary thyroid carcinoma in recent years is likely related to increased and earlier diagnosis.
APC rs459552 AT
ATM rs189037 GG
DIRC3 rs966423 TC
FAS kgp969760 TT
FOXE1 rs965513 AA
FOXE1 rs1867277 GG
FOXP3 rs2280883 TT
Fas rs1571013 AA
Fas rs1800682 GG
IL-27 kgp5444132 AA
NRG1 rs2439302 GC
RET rs1799939 AG
TERT rs10069690 CC
TERT rs2736100 AA
VEGFA rs3025040 CC
XRCC1 rs1799782 AG
XRCC3 rs1799796 TC

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Overall Risk Score
Risk Range
Related Factors
Environment - Ionizing radiation
Possible - Enlarged thyroid gland

disease history

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8. Nasopharyngeal cancer
Nasopharynx cancer or nasopharyngeal carcinoma (NPC) is the most common cancer

originating in the nasopharynx, most common in males. It is a squamous cell carcinoma or an
undifferentiated type. Signs and symptoms related to the primary tumor include trismus, pain,
otitis media, nasal regurgitation due to paresis (loss of or impaired movement) of the soft
palate, hearing loss and cranial nerve palsy (paralysis).
APEX1 rs1760944 TT
CD209 rs4804803 AA
CDKN2A rs1412829 AA
CLPTM1L rs401681 TC
CLPTM1L rs31489 AC
HLA-A rs2860580 AG
HLA-F rs3129055 AG
LOC105375015 rs2894207 TT
MECOM rs6774494 GG
NFKBIA rs696 TC
TNFRSF19 rs9510787 AA
TP53 rs1042522 GG
XRCC3 rs861539 GG
intergenic rs28421666 AA
Overall Risk Score


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Risk Range
Related Factors
Environment - Epstein-Barr virus (EBV) infection
Life style - High salt-cured food intake

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9. Pancreatic cancer
Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach,
begin to multiply out of control and form a mass. It is the seventh highest cause of death from
cancer worldwide. Pancreatic cancer rarely occurs before the age of 40, and more than half
of the cases occur in those over 70. Risk factors for pancreatic cancer include tobacco
smoking, obesity, diabetes, and certain rare genetic conditions. About 25% of cases are
linked to smoking, and 5% to 10% are linked to inherited genes.
ABO rs505922 TC
ABO rs657152.1 AC
ADAMTS13 rs687289 AG
BACH1 rs372883 TC
CLPTM1L rs401681 TC
DAB2 rs2255280 AC
DPP6 rs6464375 CC
FAM19A5 rs5768709 AG
Intergenic rs1427593 TC
LINC01173 rs6736997 CC
LOC105370243 rs1585440 GG
LOC105375739 rs10088262 AG
NOC2L exm2264981 AA
NR5A2 rs3790844 AG
NR5A2 rs10919791 AG
PARK2 rs3016539 TT
PRLHR rs12413624 TT
RNF43 rs2257205 TC
TFF1 rs1547374 AG

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Overall Risk Score
Risk Range
Related Factors
Environment - Passive smoking

- Active smoking
Possible - Chronic pancreatitis

disease history - Diabetes

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10. Lung cancer
Lung cancer is the most common fatal cancer worldwide. Environmental factors are the major
causes of lung cancer, and genetic factors likely also contribute to lung cancer development.
The vast majority (85%) of cases of lung cancer are due to long-term tobacco smoking.
These cases are often caused by a combination of genetic factors and exposure to radon
gas, asbestos, second-hand smoke, or other forms of air pollution.
CASC8 rs6983267 GG
CASP8 rs3834129 II
CHRNA3 rs1051730 GG
CHRNA3 rs6495309 TC
CLPTM1L rs402710 TC
CYP1B1 rs9341266 GG
FAS rs2234767 AA
FASL rs763110 CC
HYKK rs8034191 TT
IL17A rs2275913 AG
LOC105370113 rs753955 AG
LOC727677 rs1447295 CC
MIR146A rs2910164 GC
MIR196A2 rs11614913 TC
MTMR3 rs36600 CC
REV3L rs462779 AA
REV3L kgp3738595 AA
STK32A rs2895680 TT
TERT rs401681 TC
TERT rs2736100 AA
TP63 rs10937405 CC
VTI1A rs7086803 GG
XPA rs1800975 TC

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Overall Risk Score
Risk Range
Related Factors
Environment - Chronic obstructive pulmonary disease
- Asbestos exposure
- Passive smoking
- Air pollution
Life style - Active smoking

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11. Liver cancer
Liver cancer is globally the sixth most frequent cancer and the second leading cause of death
from cancer. The major cause of liver cancer is cirrhosis due to hepatitis B, hepatitis C, or
alcohol. Other causes include aflatoxin, non-alcoholic fatty liver disease, and liver flukes.
Symptoms of liver cancer may include a lump or pain in the right side below the rib cage,
swelling of the abdomen, yellowish skin, easy bruising, weight loss, and weakness. The
diagnosis may be supported by blood tests and medical imaging with confirmation by tissue
biopsy.
C2 rs9267673 CC
EFCAB11 rs12100561 GG
GRIK1 rs455804 AC
HLA-DPA1 rs3077 GG
HLA-DPB1 rs9277378 AG
KCNH4 rs1053004 GG
KIF1B rs17401966 AG
LOC100287329 rs1800630 AC
MIR196A2 rs12304647 AA
MTHFR rs1801131 TT
STAT4 rs7574865 TT
Overall Risk Score

Risk Range

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Related Factors
Environment - Liver flukes
- Hepatitis infection
Life style - Alcohol consumption
Possible - Cirrhosis
disease history

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12. Cervical cancer
Cervical cancer is due to the abnormal growth of cells that develops from the cervix, the lower
part of the womb in female reproductive system. It is both the fourth most common cause of
cancer and the fourth most common cause of death from cancer in women worldwide.
Infection with the virus called human papillomavirus is the greatest risk factor for cervical
cancer. HPV vaccines protect against between two and seven high-risk strains of this family
of viruses and may prevent up to 90% of cervical cancers. Other risk factors include smoking,
a weak immune system, birth control pills, starting sex at a young age, and having many
sexual partners, but these are less important. Guidelines recommend continuing regular Pap
tests.
CDKN1A rs1801270 CC
COL11A2P1 rs4282438 GG
CTLA4 rs5742909 CC
EPCAM rs1126497 TC
IL12B rs3212227 GG
LOC105379315 rs11985951 TT
LOC284454 rs895819.2 TT
MIR218-2 rs11134527 AA
MMP2 rs243865 CC
MMP7 rs11568818 TT

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Overall Risk Score
this disease is 2.51. Compared to the overall population, your overall risk is High
Risk Range
Related Factors
Environment - HPV infection
- Passive smoking
Life style - Active smoking
- Birth control pills
Recommendations
- Regular screening tests starting at age 21
- Getting an HPV Vaccine, recommended for preteens (both boys and girls) aged 11 to 12
years, but can be given as early as age 9 and until age 26
- Don't smoke
- Use condoms during sex
- Limit your number of sexual partners

- Healthy choices: Avoiding tobacco, limiting alcohol intake, keeping a healthy weight
Related tests
- Liquid based cytology, human papyllomavirus (HPV) DNA test

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DISCLAIMER
Thank you for using our test for your healthcare lab testing. Please note that the information provided through this
test is not intended to be medical advice and should not be relied on as such. There is no doctor-patient relationship
between customer of this test and any doctor or other healthcare provider engaged by this test. It is important that
you communicate with your physician or other appropriate healthcare provider so that together you can integrate the
pertinent information to determine your health status. The information provided through this test is not intended to
substitute for such consultations with your physician or other appropriate healthcare provider nor for medical advice
specific to your health condition.
This is not a diagnostic test and not to be considered as a purpose of diagnosis of any diseases. This test is meant
only for understanding susceptibility of getting diseases based on your genetic makeup. Clinician should use their
own clinical judgment and not base clinical decisions solely on this document. Any test or medication mentioned in
the report should be taken under doctor’s supervision. This report must be given only in the presence of genetic
counselor or medical professional to explain the findings and implications. PT Prodia Widyahusada Tbk(“Prodia”) will
not be liable for any direct, indirect, consequential, special, exemplary, or any other damages.
This test was developed and its performance characteristics were determined by Prodia. The laboratory is regulated
under the law of Republic of Indonesia. This test is used for clinical purposes.
If you have any questions about this report or wish to speak with one of Prodia's genetic counselors, please contact
us through our website.
Risk of Laboratory Technical Problems or Laboratory Error
Our testing laboratory has standard and effective procedures in place to protect against technical and operational
problems. However, such problems may still occur. The testing laboratory receives samples collected by patients
and physicians. Problems in shipping to the laboratory or sample handling can occur, including but not limited to
damage to the specimen or related paperwork, mislabeling, and loss or delay of receipt of the specimen. Laboratory
problems can occur that might lead to inability to obtain results. Examples include, but are not limited to, sample
mislabeling, DNA contamination, un-interpretable results, and human and/or testing system errors. In such cases,
the testing laboratory may need to request a new sample. However, upon re-testing, results may still not be
obtainable.
There is a small chance that the laboratory could report inaccurate information. For example, the laboratory could
report that a given genotype is present when in fact it is not. Any kind of laboratory error may lead to incorrect
decisions regarding medical treatment and/or diet and fitness recommendations. If a laboratory error has occurred or
is suspected, a health care professional may wish to pursue further evaluation and/or other testing. Further testing
may be pursued to verify any results for any reason.
General Limitations
The purpose of this test is to provide information about how a tested individual’s genes may affect risk for specific
common health conditions. Tested individuals should not make any changes to any medical care (including but not
limited to changes to dosage or frequency of medications, diet and exercise regimens, or pregnancy planning) based
on genetic testing results without consulting a health care professional.
The science behind the significance or interpretation of certain testing results continues to evolve. Although great
strides have been made to advance the potential usefulness of genetic testing, there is still much to be discovered.
Genetic testing is based upon information, developments and testing techniques that are known today. Future
research may reveal changes in the interpretation of previously obtained genetic testing results. For example, any
genetic test is limited by the variants being tested. The interpretation of the significance of some variants may
change as more research is done about them. Some variants that are associated with disease, drug response, or
diet, nutrition and exercise response may not be tested; possibly these variants have not yet been identified in
genetic studies.

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Many of the conditions that are tested are dependent on genetic factors as well as non-genetic factors such as age,
personal health and family health history, diet, and ethnicity. As such, an individual may not exhibit the specific
disease consistent with the genetic test results.
Another limitation for some conditions, is that genetic associations have been studied and observed in Admixed
American, African, East Asian, South Asian, and European populations only. In this case, the interpretations and
recommendations are made in the context of these studies, but the results may or may not be relevant to tested
individuals who are of mixed ethnicities.
Based on test results and other medical knowledge of the tested individual, health care professionals might consider
additional independent testing, or consult another health care professional or genetic counselor.

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- US Preventive Services Task Force, Bibbins-Domingo K, Grossman DC, Curry SJ, Davidson KW, Epling JW,
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Patient ID : 203039100013_R12C02
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Name : 203039100013_R12C02

Date of Birth : 06/06/1978

THIS IS YOUR PERSONAL CANCER RISK BASED ON YOUR

CANCER RISK : SINGLE NUCLEOTIDE POLYMORPHISMS (SNPs)

WHAT IS THIS RESULT BASED ON ?

GWAS AND RISK SCORING

DOES IT ALL DEPEND ON MY GENES?

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

IF THE RESULT INDICATES THAT I HAVE HIGHER RISK FOR

IF THE RESULT REFLECTS THAT I HAVE LOW RISK FOR

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

REPORT 1. Key Risks

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

LIFE STYLE RECOMMENDATIONS

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

Gene Gene variant Genotype

Overall Risk Score

0.19 Low Risk Average Risk Potential Risk High Risk

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

- Red meat consumption

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

Gene Gene variant Genotype

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

Overall Risk Score

0.09 Low Risk Average Risk Potential Risk High Risk

- Lack of physical activity

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

Gene Gene variant Genotype

Overall Risk Score

0.45 Low Risk Average Risk Potential Risk High Risk

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

- Red meat consumption

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

Gene Gene variant Genotype

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

Overall Risk Score

-0.59 Low Risk Average Risk Potential Risk High Risk

Life style - Lack of exercise

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

Gene Gene variant Genotype

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

0.79 Low Risk Average Risk Potential Risk High Risk

- Red meat consumption

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

Gene Gene variant Genotype

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

-0.18 Low Risk Average Risk Potential Risk High Risk

Life style - Inadequate diet

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

Gene Gene variant Genotype

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

0.72 Low Risk Average Risk Potential Risk High Risk

Possible - Enlarged thyroid gland

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

Nasopharynx cancer or nasopharyngeal carcinoma (NPC) is the most common cancer

Gene Gene variant Genotype

Overall Risk Score

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

0.2 Low Risk Average Risk Potential Risk High Risk

Life style - High salt-cured food intake

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0

Gene Gene variant Genotype

Name : 203039100013_R12C02 Ref ID : R20190301001 Report Version : V.2.0