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Communicable Diseases QP - AQA Biology GCSE
Communicable Diseases QP - AQA Biology GCSE
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___________________________________________________________
(1)
Q1.
Viruses cause disease. A vaccine can protect humans from a viral disease.
(a) What name is given to microorganisms that cause disease? (d) What does the vaccine contain?
(1) (1)
(b) How do viruses cause the symptoms of disease? In some cases, a first vaccination needs to be followed by a second vaccination
sometime later.
Tick (✓) one box.
(e) Which graph shows how the concentration of antibodies in a person’s
blood changes after the first and second vaccinations?
Viruses engulf white blood cells,
destroying them. Tick (✓) one box.
Figure 1
(c) Suggest one reason why viruses are not classed as cells.
___________________________________________________________
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The table below shows the rate of photosynthesis in four different tobacco plants.
Rate of
Level of TMV
Tobacco photosynthesis
infection in
plant in arbitrary
plant
units
A None 15
B Mild 13
C Medium 7
D High 3
You should:
• label the y-axis
• add the correct scale to the y-axis
• plot the data from the table above
• label each bar.
Figure 2
(1)
Flower
(5)
Leaf (h) What conclusion can be made from the data in the table above?
___________________________________________________________
Root
___________________________________________________________
(1) (1)
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(i) Explain why a high level of TMV infection reduces growth in a plant.
Platelets kill the microorganisms.
___________________________________________________________
Do not refer to viruses in your answer. In a vaccine the measles virus is _______________.
___________________________________________________________ If the measles virus enters the body after vaccination the immune system
(1) reaction
(b) Which two defence systems prevent microorganisms infecting the human will be _______________.
body? (2)
Tick (✓) two boxes. (e) How is the measles virus spread from one person to another?
___________________________________________________________
Hairs on the skin trap microorganisms. (1)
The skin is a barrier covering the whole body. Every two days after the party, the doctors recorded when the other 22 children
first showed chickenpox spots.
(2)
The table below shows the results.
(c) If microorganisms enter the human body the immune system can destroy
the microorganisms. Day when chickenpox spots first Number of
showed children
How does the immune system destroy microorganisms?
2 0
Tick (✓) one box.
4 0
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6 0 Figure 1
8 0
10 1
12 1
14 6
16 4
18 2
20 0
Total 14
(f) What was the range for the days on which children first showed chickenpox
spots?
(a) How will the poisonous berries help the deadly nightshade plant to survive?
Use the table above.
___________________________________________________________
From day __________ to day __________
(1) ___________________________________________________________
(1)
(g) Incubation time is the usual time from exposure to a pathogen until the first
symptoms appear. (b) Which type of defence mechanism are the berries?
Suggest the most likely incubation time for chickenpox.
Tick (✓) one box.
Incubation time = _______________ days
Chemical
(1)
(h) Suggest one reason why some of the children did not develop chickenpox.
Mechanical
___________________________________________________________
___________________________________________________________ Physical
(1)
(1)
(i) One mother gave antibiotics to her child who had chickenpox.
Figure 2 shows part of a gorse plant.
Suggest why this child did not recover more quickly than the other children
who had chickenpox. Figure 2
___________________________________________________________
___________________________________________________________
(1)
(Total 11 marks)
Q3.
Figure 1 shows part of a deadly nightshade plant.
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___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
(3)
(f) The roots of the gorse plant have bacteria that turn nitrogen gas into nitrate
ions.
(d) The green leaves of the gorse plant make glucose for the plant to use. ___________________________________________________________
(2)
What are two uses of glucose in the gorse plant?
(g) The roots of gorse plants can be infected by honey fungus.
Tick (✓) two boxes.
The honey fungus produces tiny spores underground.
For defence
Suggest how the honey fungus spores travel from the roots of an infected
gorse plant to the roots of a healthy gorse plant.
For respiration
___________________________________________________________
Doctors want to trial the drug from gorse seeds to see if it can treat diarrhoea.
To store as starch
(h) Which two factors must the doctors test the drug for in the trial?
Describe the method the student could use to test the liquid from the cells Dosage
for glucose.
___________________________________________________________
Taste
___________________________________________________________
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Placebos ___________________________________________________________
(1)
(1)
(c) Suggest one reason why the statement may not be valid.
(Total 14 marks)
___________________________________________________________
Q4. ___________________________________________________________
Mosquitoes carry a pathogen that causes malaria. (1)
(a) What type of pathogen causes malaria? Table 2 shows information about the number of deaths from malaria in the same
area of Africa.
Tick (✓) one box.
Table 2
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___________________________________________________________ Measles
(1)
___________________________________________________________ (1)
___________________________________________________________ (c) Using a condom can stop the bacteria being passed to another person
(6) during sexual intercourse.
(Total 11 marks)
Suggest a different way the man could avoid passing the bacteria on to
someone else.
Q5. ___________________________________________________________
A man has the following symptoms:
___________________________________________________________
• yellow discharge from his penis
(1)
• pain when urinating.
A scientist investigated the effect of three different antibiotics on three different
(a) The man has a bacterial infection.
types of bacteria, A, B and C.
What is the most likely cause of the man’s symptoms?
This is the method used.
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2. Put three separate paper discs each containing one of the antibiotics (1, 2 and A small volume of raw milk was placed in a counting chamber in a special type of
3) onto the agar plate microscope slide.
3. Put the agar plate into an incubator for 48 hours. Figure 2 shows what the counting chamber looked like when viewed using a
microscope.
4. Repeat steps 1-3 for bacteria B and for bacteria C.
Figure 2
Figure 1 shows the scientist’s results.
Figure 1
Table 1
Number of bacteria in
(d) Compare the effectiveness of the three antibiotics at killing the different Milk sample
counting chamber
types of bacteria. E 15
F 12
___________________________________________________________
G 13
___________________________________________________________ H 16
___________________________________________________________
Sample E
___________________________________________________________
Sample F
___________________________________________________________
Sample G
___________________________________________________________
___________________________________________________________ Sample H
___________________________________________________________ (1)
___________________________________________________________ (f) Calculate the mean number of bacteria in the four samples in Table 1.
___________________________________________________________ ___________________________________________________________
(6)
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___________________________________________________________ P Q R S
___________________________________________________________ (1)
___________________________________________________________ Q6.
Eating food containing Salmonella bacteria can cause illness.
Volume of counting chamber = ______________________________ mm3
(a) Two symptoms of infection by Salmonella are vomiting and diarrhoea.
Calculate the mean number of bacteria per mm3 of milk in the samples.
What causes these symptoms?
Use the equation:
___________________________________________________________
___________________________________________________________
(1)
___________________________________________________________
(b) Give two ways a person with a mild infection of Salmonella can help
___________________________________________________________ prevent the spread of the bacteria to other people.
___________________________________________________________
Milk is heated to reduce the number of bacteria it contains before it is sold for
humans to drink. 2.
___________________________________________________________
Milk with more than 20 000 bacteria per cm3 cannot be sold for humans to drink.
___________________________________________________________
Table 2 shows the number of bacteria per cm3 in four different samples of milk. (2)
Table 2
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(c) In very serious infections of Salmonella, a doctor can prescribe drugs to kill
the bacteria.
What type of drug can the doctor prescribe to kill the bacteria?
___________________________________________________________
___________________________________________________________
(1)
(d) A person with AIDS may take longer than a healthy person to recover from
a Salmonella infection.
Explain why.
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
(2)
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___________________________________________________________
(1)
(Total 11 marks)
Q7.
Many diseases can be treated using drugs.
Bacteria
The Petri dish was placed in an incubator at 25 °C for 48 hours.
After 48 hours, the scientist calculated the area around each paper disc where Fungi
no bacteria were growing.
___________________________________________________________
___________________________________________________________
(1)
(h) Give one change to the investigation that would allow the scientist to check
if the results are repeatable.
___________________________________________________________
___________________________________________________________
(1)
Suggest one other factor the restaurant owner should consider when
choosing which cleaning liquid to use. (2)
___________________________________________________________
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Q8.
(c) New drugs must be tested before they can be used.
Rose black spot is a disease of roses.
Give one reason why drugs should be tested.
(a) What type of microorganism causes rose black spot?
___________________________________________________________
Tick one box.
___________________________________________________________
(1)
A bacterium
(d) Doctors have developed a new drug.
The new drug has been tested on live animals. A fungus
A virus
Testing on animal tissues in a laboratory
(1)
Testing on healthy volunteers (b) Explain how different types of organism defend themselves against
microorganisms.
Testing on patients with the disease ___________________________________________________________
___________________________________________________________
Testing on the whole human population
___________________________________________________________
(1)
___________________________________________________________
(e) Vaccination can be used to prevent an illness in a person.
___________________________________________________________
Explain how a vaccination can prevent an illness.
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________ (6)
___________________________________________________________
___________________________________________________________
___________________________________________________________
(4)
(Total 9 marks)
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To save money
(1)
(Total 11 marks)
Q9.
This is the method used. A virus called RSV causes severe respiratory disease.
1. Remove the lid of the Petri dish. (a) Suggest two precautions that a person with RSV could take to reduce the
spread of the virus to other people.
2. Remove the lid of the bottle containing the bacteria.
3. Use the inoculating loop to remove some of the bacteria from the 1.
bottle. ___________________________________________________________
4. Spread the bacteria over the agar using the inoculating loop. ___________________________________________________________
5. Put the lid back on the Petri dish.
6. Put the Petri dish into an incubator at 25 °C for 24 hours. 2.
___________________________________________________________
Steps 1−5 could cause the sample of the bacteria on the petri dish to be
contaminated. ___________________________________________________________
(2)
Give three improvements to the method to prevent contamination.
(b) One treatment for RSV uses monoclonal antibodies which can be injected
1. into the patient.
___________________________________________________________
Scientists can produce monoclonal antibodies using mice.
___________________________________________________________ The first step is to inject the virus into a mouse.
2. Describe the remaining steps in the procedure to produce monoclonal
___________________________________________________________ antibodies.
___________________________________________________________ ___________________________________________________________
3. ___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
(3) ___________________________________________________________
(d) Why did the student grow the bacteria at 25 °C rather than at 40 °C? ___________________________________________________________
___________________________________________________________
So the bacteria grew more quickly
___________________________________________________________
(3)
So the bacteria grew more slowly
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(f) Evaluate how well the data in the table above supports the conclusion:
(c) Describe how injecting a monoclonal antibody for RSV helps to treat a
patient suffering with the disease. ‘monoclonal antibodies are more effective at treating RSV than a
placebo’.
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
___________________________________________________________
(2) ___________________________________________________________
(2)
A trial was carried out to assess the effectiveness of using monoclonal (Total 12 marks)
antibodies to treat patients with RSV.
___________________________________________________________
(1)
(e) Calculate the total number of patients admitted to hospital with RSV during
the trial.
___________________________________________________________
___________________________________________________________
(3)
___________________________________________________________
___________________________________________________________
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Headache
Rash
Vomiting
Yellow discharge
(2)
(3)
(c) The table below shows the number of people in the UK diagnosed with
gonorrhoea in different years. (d) Describe the patterns in the numbers of males and females with
gonorrhoea from 2005 to 2013.
Number of people
Use the data in the graph.
diagnosed
with gonorrhoea in
___________________________________________________________
thousands
___________________________________________________________
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___________________________________________________________
(2)
(Total 13 marks) Q12.
Lungworm is an infection.
1.
___________________________________________________________
___________________________________________________________
2.
___________________________________________________________
___________________________________________________________
(2)
(b) In 2014 the Ebola virus killed almost 8000 people in Africa.
Explain what testing must be done before this new drug can be used to Dog © Eriklam/iStock/Thinkstock, snail © Karandaev/iStock/Thinkstock
treat people.
(a) What type of organism is represented by the snail in the lifecycle of the
___________________________________________________________ lungworm?
___________________________________________________________
Tick one box.
___________________________________________________________
Fungus
___________________________________________________________
___________________________________________________________ Parasite
___________________________________________________________
Protist
___________________________________________________________
___________________________________________________________
Vector
___________________________________________________________
(1)
___________________________________________________________
(6) (b) Suggest how the spread of the lungworm disease can be prevented.
(Total 8 marks)
___________________________________________________________
___________________________________________________________
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___________________________________________________________
Tick (✔) one box.
___________________________________________________________
large amounts of dead pathogens
___________________________________________________________
(3)
large amounts of live pathogens
(c) Malaria is a disease spread by mosquitoes.
Describe two ways to control the spread of malaria. small amounts of dead pathogens
1. (1)
___________________________________________________________
(ii) The advances in medicine had an effect on death rate.
___________________________________________________________
Describe the effect these advances had between 1750 and 1850.
2.
___________________________________________________________ To gain full marks you should include data from the graph above.
___________________________________________________________ _______________________________________________________
(2)
(Total 6 marks) _______________________________________________________
_______________________________________________________
Q13.
Pathogens are microorganisms that cause infectious diseases. _______________________________________________________
(2)
(a) The graph shows the percentage of children under 5 years old who died
from infectious diseases, in the UK, in four different years. (b) Antibiotics were developed in the 1940s. Antibiotics kill bacteria.
(ii) The use of antibiotics has not reduced the death rate due to all
diseases to zero.
1.
_______________________________________________________
_______________________________________________________
2.
_______________________________________________________
_______________________________________________________
(i) Between 1750 and 1850 vaccinations were also developed. (2)
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Give one reason why companies testing new antibiotics grow bacteria at
37 °C.
___________________________________________________________
___________________________________________________________
(1)
(Total 7 marks)
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