Literature Review:

In patients with short-term percutaneous central venous catheter (CVC), it is recommended that
a dressing be applied to the catheter insertion site to prevent catheter-related infections.
Objectives:

The aim of this investigation was to evaluate the viability of conducting a randomized controlled trial to
contrast the effectiveness of polyurethane dressing and chlorhexidine-impregnated dressing in
preventing catheter-related infections in critically ill adult patients undergoing short-term percutaneous
coronary intervention (CVC).

Methods:
115 patients with a CVC were randomly assigned to receive either transparent polyurethane dressing
(polyurethane group) or chlorhexidine-impregnated gel dressing (chlorhexidine gel group). Protocol
violations, missing data, eligibility, and recruiting statistics were among the findings related to feasibility.
The main indicator of effectiveness was the existence of the same microbe colonizing the skin swab
around the catheter insertion site and the catheter tip.
Results:
115(22%) of the 526 patients whose eligibility was evaluated for randomization were included, while
411(78%) did not match the requirements. The final sample included 47 people in the polyurethane group
and 54 in the chlorhexidine group. While the difference was not statistically significant (p = 0.51), 13% of
subjects in the chlorhexidine group and 8% in the polyurethane group had the same bacterium colonies
their skin and catheter tip. Catheter tip colonization, skin site colonization, catheter insertion site
infection, catheter-related bloodstream infection, skin irritation, and the frequency of unscheduled
dressing changes did not differ between the two groups.
Result:
Our initial findings suggested that it would be possible to conduct a sizable randomised controlled study.
This work offers important data that can be utilised to create more comprehensive studies to prevent
infection in patients undergoing short-term percutaneous CVC when dressing with polyurethane or
chlorhexidine.