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IMPROVES
MEDICAL
IMAGING
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Vol. 65, No. 6 NOVEMBER/DECEMBER 2023 CONTENTS 1
9 17
EDITORIAL STAFF
TOUCH POINTS
Published by AspenCore
“Improving the precision and efficiency of image analysis is a We also look at the top 10 circuit protection devices
major focus of current research in both AI and medical imaging.” introduced in 2023 (see page 14). One of the biggest trends for
A major development in medical imaging techniques is these protective devices is miniaturization, but they also need
the increased use of deep-learning algorithms, which can to withstand harsh environmental conditions. ☐
sift through massive datasets in search of abnormalities and Gina Roos
NOVEMBER/DECEMBER 2023 • electronicproducts.com • ELECTRONIC PRODUCTS
Innovations impacting products, technology, and applications OUTLOOK 3
A sneak peek at
next-generation
ultrasound imaging
BY ERWIN HIJZEN, Director of the MEMS Ultrasound Figure 2: Schematic cross-sections of a PMUT process flow
Program, and EPIMITHEAS GEORGITZIKIS, R&D Project
Leader of the Listen2Future Project, imec include: (a) back-plane substrate with optional TFT and/or
www.imec-int.com flexible layer; (b) front-plane substrate with metal-insulator
T
metal stack; (c) bonding of front plane to back plane and
he use of sound waves for non-invasively visualizing a fetus removal of front-plane substrate; and (d) metal via interconnect
in the womb, via ultrasound imaging, is widely recognized. for electrical connection between front and back plane.
By emitting high-frequency sound waves into the body and
converting their echo into electrical signals, real-time images can be
constructed. Apart from medical imaging, these sound waves find of a crystalline silicon one, area restrictions were lifted. Additionally,
application in biometric identification and gesture recognition in this next-generation PMUT array exhibited 10× the acoustic pres-
automotive and virtual-reality applications and various other fields. sure compared with the previous generation.
Currently, ultrasound transducers are commonly produced Image acquisition up to 10-cm distance is shown in Figure 1
using silicon semiconductor facilities. For high-resolution with pressures above 7 kPa in water, making it suitable for high-
medical imaging with large-area coverage, large sensors are performing ultrasound imaging.
required, which is challenging for silicon-based sensors because The array, featuring an AlScN piezoelectric layer, achieves
of their high cost per square millimeter. impressive image acquisition and beam steering up to 10 cm in
water. This advancement paves the way for complex ultrasound
PMUT arrays for large-area imaging applications on curved surfaces, revolutionizing medical imag-
In 2021, imec introduced flat panel display (FPD)-compatible ing and monitoring.
piezoelectric micromachined ultrasound transducer (PMUT)
arrays on glass. As a result of moving from wafer-based to
FPD-compatible processes, cost-effective upscaling of ultra-
sound sensors was made possible.
More specifically, due to its compatibility with existing thin-
film transistor back planes and because this transducer tech-
nology is not hampered by wafer-size restrictions, large-area
processing capabilities with PMUT arrays were made possible.
However, the performance of the polymeric piezoelectric mate-
rial was not yet sufficient for high-quality medical imaging.
Now, imec has demonstrated a second-generation PMUT array
with another piezoelectrical material: aluminum scandium nitride
(AlScN). With the earlier implementation of a glass substrate instead
Prospects for flexible ultrasound imaging monitoring outside hospitals, without the need for a physician.
Next steps include maturing the technology and tuning the device As a result, the collaboration brings non-invasive, physician-free
to specific frequencies. In doing so, this technology will enable large cardiac monitoring a step closer to reality.
ultrasound arrays on, for instance, curved surfaces, such as sensors As part of the Listen2Future project, further development
for the human body or car dashboards, facilitating integration of of a flexible ultrasound patch is ongoing. Listen2Future is an
ultrasound functions on large, non-planar surfaces. As a result, excit- EU-funded project addressing and benchmarking piezoelectric
ing opportunities for innovative ultrasound applications will emerge. acoustic transducers with 27 partners across seven countries,
In collaboration with Pulsify Medical, imec has already coordinated by Infineon Technologies Austria AG. ☐
created a proof-of-concept rigid medical patch for cardiac
monitoring, paving the way for non-invasive and longitudinal This article originally ran on EDN at tinyurl.com/36wpefkh.
Q
uantum technology—encom- at Bosch Quantum Sensing.
passing computing, commu- Bosch estimates the annual global
nication, imaging and sen- market for quantum sensors serving
sors—is starting to become visible in the medical and mobility applications will
commercial arena with the promise to reach the mid-single-digit billions by the
offer exceptional reliability and less vul- middle of the next decade. The company
Figure 2: Medical and mobility applications
nerability to signal jamming and other is also confident that quantum sensor
could offer quantum sensors early access to
electromagnetic-interference issues that capabilities could lead to additional sens-
commercial markets.
are increasingly common in today’s light- ing applications.
and sound-based data sensors. interference, quantum sensors are resis-
Case in point: Bosch has announced Medical and mobility applications tant to external influences because they
plans to integrate quantum sensors onto Quantum sensors can provide far more work by measuring the earth’s unchanging
chips. The Stuttgart, Germany–based sen- data than today’s electrocardiography magnetic field. Next, quantum sensors
sor specialist has also developed a sensor (ECG) and thus measure the heart’s nat- could be used to precisely measure the
prototype that it claims is currently the ural magnetic field while enabling simple magnetic field of the electric current in
smallest, about the size of a cellphone. measurements over a longer period. An electric vehicles and thus determine the
ECG machine is applied directly to the exact charge level of the battery.
skin by using electrodes, but if electrodes Quantum sensors provide qualita-
slip, measurements are inaccurate. Addi- tively new data about our world, which
tionally, attaching the ECG machine uses in turn can be turned into valuable
precious time in an emergency. information about our environment.
On the other hand, quantum sensors That premise now increasingly seems
can be incorporated into things like items within reach, as shown by the Bosch
of clothing or mattresses. That speeds announcement. But while quantum sen-
up diagnosis in the emergency room sors still require a lot of technological
Figure 1: The quantum sensor prototype is
and makes monitoring at home easy advancements, their leap from research
the size of a cellphone.
and precise. As a result, the prospect of to the commercial arena bodes well for
contactless early detection of atrial fibrilla- their future.
Bosch, working on quantum technol- tion—one of the causes of life-threatening Bosch, in its announcement, has
ogies for nearly a decade, will work with strokes, heart failure and dementia—looks made known its goal to acquire a leading
pilot customers in the medical and mobility within reach for the first time. position in the quantum sensor market
industries on specific applications over the Likewise, in mobility, quantum sensors by the end of the decade. ☐
IMAGES: BOSCH
next two years. As part of this undertaking, can facilitate ultra-precise navigation in
the German electronics firm established the air, on the road and on water. For This article originally ran on EDN at
Bosch Quantum Sensing in early 2022. navigation, while GPS is susceptible to tinyurl.com/49d74bt7.
NOVEMBER/DECEMBER 2023 • electronicproducts.com • ELECTRONIC PRODUCTS
Medical Wearables FEATURE 5
M
edical wearables are making a Hospital-grade wearables also require Liu said hospital-at-home is an
significant difference in patient some kind of regulatory control like the emerging RPM segment in which hospi-
care, enabling continuous FDA, and the devices themselves have to tal providers are treating the home envi-
remote monitoring in the home. Over be very optimized to a patient’s physiol- ronment as an extension of the hospital.
the past several years, consumer wear- ogy, Liu said. “For example, if you have a Cardiac is one of the top applications
ables for health and fitness monitoring wristwatch that can track your activity and driving it, but it can be for any kind of
like Apple Watch and Fitbit have changed take a temperature reading, it is not going serious or acute condition that requires
the way people monitor their health, to be hospital-grade because of location the clinicians to still monitor the patients
from tracking how many steps they walk and exposure to ambient temperatures. very carefully after being treated at the
daily to heart rate monitoring and, more Hospital-grade temperature monitoring hospital for an acute condition, he said.
recently, atrial-fibrillation detection. will have to be worn in a position on the
There have also been advances in sports body, such as under the armpit, where you Continuous monitoring and RPM
wearables that help athletes improve can get an accurate measurement.” One of the biggest benefits that medical
their performance and monitor for inju- wearables provide is the capability of
ries, all done by collecting and analyzing continuously monitoring a patient’s vital
data from the sensors. signs, which were previously available
The next level of transformation in only in hospital and clinic environments.
healthcare is medical wearables that The big trend now is hospital-at-home
enable the remote patient monitoring applications, in which patients are mon-
(RPM) of acute and chronic diseases. itored remotely, in addition to chronic
Since the Covid-19 pandemic, medical disease management, particularly for
wearables have experienced wider adop- diabetes and cardiovascular diseases,
tion, providing healthcare professionals enabling early detection and treatment.
with a new way to monitor patients Medical wearables are also getting
outside of the hospital environment. The Vivalink temperature patch provides more accurate and can be worn without
The world of healthcare wearables was medically precise readings for RPM. a charge for a longer length of time. One
popularized by the consumer movement example is Vivalink’s multi-parameter
and has since progressed to more serious Vivalink recently conducted a survey wearable electrocardiogram (ECG) patch
uses of medical wearables, said Sam Liu, of healthcare providers and found that with continuous 14-day live-stream
vice president of marketing at Vivalink, 93% of respondents are using RPM capabilities. The ECG patch extends the
a digital healthcare solution provider. technologies across all cardiac rehab. The duration for remote ECG monitoring with
“During the pandemic, a lot of uses had to company offers medical-grade connected a single application of the patch, and the
do with telehealth or remote patient mon- wearable technologies for RPM and con- real-time streaming capabilities let clini-
itoring, and that was largely using teleme- tinuous in-patient vital signs monitoring. cians remotely view a patient’s live ECG
try or video conferencing combined with The survey also revealed that 68% anywhere and anytime, the company said.
certain types of medical wearables to start of clinicians have conducted some level Continuous ECG monitoring may
collecting data about the patient.” of home-based cardiac rehab, with 29% be needed after surgery and enables the
But those types of monitoring condi- conducting more or the same amount healthcare provider to monitor a patient
tions were still about maintaining health of home-based versus clinic-based. as if they were in the hospital or clinic to
and chronic condition monitoring, and The biggest driver behind the trend is quickly develop a treatment plan for any
IMAGE: VIVALINK
now it has moved into more serious acute post-myocardial infarction, otherwise abnormalities, such as arrhythmias.
monitoring, such as following a heart known as a heart attack, indicating the Vivalink also offers a Biometrics Data
attack, where a patient needs to be mon- importance of remote care in critical Platform, which accelerates the imple-
ELECTRONIC PRODUCTS • electronicproducts.com • NOVEMBER/DECEMBER 2023
6 FEATURE Medical Wearables
gies and cloud integration. Its software for therapeutics and diagnosis comes from in full synchronization to extract multi-
development kits are application- processing the data through software.” ple vital signs, ST said.
agnostic and allow customers to license AI takes it to the next level, enabling Continued on page 9
NOVEMBER/DECEMBER 2023 • electronicproducts.com • ELECTRONIC PRODUCTS
Internet of Medical Things FEATURE 7
C
hronic health conditions, such as diabetes, asthma and with an NFC-enabled phone to transfer the data onward to a
arthritis, require the long-term use of medications, physician’s cloud service.
which patients in their own homes often manage. Smart
connected medical devices can provide significant support for Improving patient medication adherence
improving patient self-care, both in terms of drug administra- Advances in NFC technology can thus go a long way toward
tion and authentication, as well as usage reminders and adher- addressing some of the most challenging issues in medical
ence advice. Recent advancements in near-field communication care today, such as ensuring patients can better manage their
(NFC) tagging can revolutionize home-based care and data-led chronic health conditions. According to the World Health
treatments, improving outcomes for patients and supporting Organization (WHO), patient adherence to long-term medica-
their health over the long term. tion therapy in developed countries averages at about 50%, and
in developing countries, the rates are even lower.
The promise of networked medical devices Patients sometimes experience delays in filling their
The internet of medical things (IoMT) refers to the network of prescriptions, face difficulties in comprehending proper
medical devices, sensors and applications that are connected dosing instructions or can forget to take their medications at
and interconnected through the internet. It encompasses vari- designated times. The consequences of lapses in medication
ous technologies and devices, including wearable fitness track- adherence can lead to poor health outcomes for patients and
ers, remote patient-monitoring systems, smart medical devices an increased burden on healthcare systems, but NFC tags now
and health-monitoring apps. The IoMT is particularly useful have the potential to address this issue.
for collecting, analyzing and exchanging health-related data With a simple tap of a phone on an NFC-tagged product,
in real time, allowing for improved patient self-care, remote patients can quickly access documents and videos that pro-
patient monitoring, personalized treatments and improved vide valuable information, such as instructions on drug usage,
decision-making by healthcare providers. potential side effects and guidance on avoiding interactions. For
NFC tags will become an increasingly important part of even better adherence, apps can also be made available to set up
the IoMT. These small wireless devices with unique identifiers reminders for their prescribed medicine doses.
can be attached to or embedded into medical monitoring and Incorporating an NFC reader into a multi-use refillable drug
treatment devices, and even attached onto medication pack- delivery device, such as an auto-injector or smart inhaler, can
aging, facilitating seamless communication and data exchange also help patients with adherence. The reader automatically
between medical products, patients and healthcare providers. authenticates the NFC tag attached to the drug consumable,
The data storage capacity, reliable security features and aug- such as a syringe or cartridge, ensuring its authenticity from a
mented functionalities like condition sensing of these advanced trusted source or viability based on the expiration date.
IMAGE: NXP SEMICONDUCTORS
NFC tags ensure reliable real-time transmission of critical Following each usage, the reader records the action, while
health information. For instance, healthcare professionals can the tag stores incremental counter values to protect against
instantly access a patient’s medication and treatment data, reuse. The data can be synchronized to one’s phone app using
drilling down to dosage levels and administration times. This Bluetooth connectivity, allowing users to track their adherence
data is captured automatically via hospital equipment, such as history. With patient consent, their adherence history can be
a smart infusion pump, which is connected to a network. In a shared with healthcare providers to facilitate comprehensive
home setting, the patient’s smart injector, for example, interacts care and personalized feedback.
ELECTRONIC PRODUCTS • electronicproducts.com • NOVEMBER/DECEMBER 2023
8 FEATURE Internet of Medical Things
kets, websites, legitimate pharmacies, clinics and even hospitals. NFC tags can also be assigned to a specific distributor and
This is not only a developing world issue: In the U.S., there location, providing traceability throughout the supply chain.
are instances where counterfeit drugs infiltrate legitimate Some tags even offer mutual authentication using a cryp-
supply chains, and approximately 1% of prescriptions filled at tographic key, restricting access to authorized readers or servers
traditional pharmacies are thought to be fake. However, most and preventing unauthorized access or manipulation of tag data.
substandard and falsified medicines in the U.S. are typically Electronically tamper-evident NFC conductive seals and
acquired through online purchases. According to the National labels can be applied to drug packaging during manufacturing
NOVEMBER/DECEMBER 2023 • electronicproducts.com • ELECTRONIC PRODUCTS
Internet of Medical Things FEATURE 9
Brand inspectors, pharmacists and consumers can verify product authenticity with their smartphones, allowing them to easily spot
counterfeit products.
to protect against unauthorized product opening. These seals immense potential for revolutionizing healthcare delivery,
irreversibly write the “once opened” status into the tag memory enhancing patients’ monitoring and therapy outcomes, and
and transmit the information to the cloud when tapped with a ultimately transforming the way healthcare is managed and
phone, providing a reliable indication of tampering. accessed globally.
Alternatively, capacitive tamper-proof tags detect changes By enabling authentication verification, tracking opening
in capacitance, comparing them with pre-configured limits status and facilitating safe handling, NFC-enabled security tags
when read with an NFC-enabled smartphone. If the limits are offer pharmaceutical companies a valuable tool to safeguard
exceeded, the “open” status is added to the SUN message. This the supply chain and ensure the safe and efficient delivery of
type of tamper detection is much more difficult for fraudsters drugs to patients. NFC technology also plays a significant role
to replicate and is suitable for integration into physical forms, in assisting patients with chronic conditions, utilizing advanced
such as bottle closures. Additionally, NFC tags with a capac- NFC smart sensing tags and mobile or cloud applications to
itive structure can serve as passive sensing devices, detect- support medication adherence and provide timely reminders
ing changes in conditions like moisture or fill level without for prescription refills.
needing a battery. NFC solutions can also deliver personalized content and
useful services that are tailored to individual needs. This not
An NFC-enabled era of IoMT advancements only adds value to pharmaceutical companies but also enhances
The combination of IoMT and NFC technology holds the overall experience and outcomes for patients. ☐
Adhesives. It has also resulted in a smart also be used in oncology to help with the
biosensing patch technology toolbox for diagnosis of thyroid cancer.
remote ECG and SCG monitoring. Dawako said the patches provide
DuPont Liveo Smart Biosensing Patch
The Liveo Soft Skin Conductive real-time, non-invasive and continuous
concept
Tape technology can be used as a skin monitoring, which enhances diagnostic
electrode for bio-signal–monitoring collaborating on the development of bio- accuracy to improve patient outcomes.
applications in single electrodes for imaging systems. The WBS Patch and The patches use different advanced
short-term monitoring and medical WBS-US patch will be able to simulta- flexible materials, including FLEXcon
wearable patches for long-term monitor- neously acquire ultrasonic imaging and OMNI-WAVE and FLEXcon dermaFLEX,
ing of seven or more days. bio-signals. with different printing technologies to
FLEXcon Global, a developer of adhe- The patches will leverage FLEXcon’s configure Dawako’s medical-grade adhesive
sive coating and laminating, and Dawako flexible adhesive, which will function as a patches in a simple and scalable way. The
Medtech, a medical device company, are disposable electrode array that can be used formal launch is expected in early 2024. ☐
ELECTRONIC PRODUCTS • electronicproducts.com • NOVEMBER/DECEMBER 2023
10 FEATURE Designer’s Guide: Sensors for Medical Applications
O
ver the past few years, there have
been remarkable breakthroughs
in the field of medical technology,
leading to a significant transformation in
patient care and diagnostic procedures. The
significance of sensors is seen in the contin-
ually evolving world of medical technology,
where these devices serve as a fundamental
component of electronic health systems that
measure and monitor diverse physiologi-
cal data, such as blood sugar levels, blood • Pressure sensors: They play a critical physiological characteristics. Pulse
pressure and respiration rate. role in several applications, such as oximeters, for example, use optical
The field of medical applications neces- monitoring blood pressure and mea- sensors to assess the oxygen satura-
sitates a significant degree of precision and suring respiration rate. Catheter-based tion levels in the bloodstream by the
dependability. The design process requires pressure sensors for cardiovascular analysis of light absorption at vari-
meticulous consideration of various ele- monitoring and blood pressure cuffs ous wavelengths. Optical sensors are
ments, including sensor accuracy, response exemplify two distinct approaches to also used in identifying biomarkers
time, battery consumption and compatibil- measuring pressure—namely, invasive and monitoring tissue oxygenation.
ity with the human body. In addition, the and non-invasive methods, respec-
sensors must conform to rigorous require- tively. The use of microelectromechan- Key sensor features
ments to guarantee the safety of patients and ical systems (MEMS) technology has The success of a medical device heavily relies
compliance with regulations. made substantial contributions toward on the quality and performance of the sen-
the reduction in size and performance sors. Here are some of the key features that
Types of sensors in medical applications improvements of pressure sensors. engineers should consider in their design.
Depending on the specific capability they • Flow sensors: In devices involving
implement, or the physical attribute they fluid dynamics, such as infusion Accuracy and reliability
measure, medical sensors can be grouped pumps, flow sensors are indispensable. It is critical to ensure the precision
into the following main classes: They ensure the precise and regulated and dependability of medical sensors.
• Electrochemical sensors: These sen- delivery of fluids, which contributes Protocols for calibration, rigorous testing
sors are extensively used to measure to the safety and efficacy of medical procedures and continuous monitoring
parameters like glucose levels and treatments. Mass airflow sensors are are fundamental aspects of sensor design.
blood gases. The functionality of primarily used in ventilation systems It is necessary to implement strategies
these sensors is based on the chemi- and respiratory care, as well as other for mitigating factors that could com-
cal reaction that occurs between the medical applications that require high promise accuracy, such as environmental
IMAGE: SHUTTERSTOCK
target analyte and electrodes, resulting accuracy, repeatability and excellent conditions and signal interference. For
in the generation of an electrical signal signal-to-noise performance. example, blood glucose monitors for dia-
that is directly proportional to the • Temperature sensors: Temperature betic patients require sensors with a high
concentration of the analyte. Electro- sensors in medical applications degree of precision to ensure the correct
chemical sensors are commonly used encompass tasks like monitoring insulin dosage.
NOVEMBER/DECEMBER 2023 • electronicproducts.com • ELECTRONIC PRODUCTS
Designer’s Guide: Sensors for Medical Applications FEATURE 11
Power consumption
Medical sensors often operate in
resource-constrained environments,
requiring energy-efficient design and
miniaturization. Implantable and
wearable devices require low power
consumption, and miniaturization allows
for unobtrusive integration with medical
equipment and patient-worn devices.
Energy efficiency is essential for wearable
devices and remote monitoring systems. ams Osram’s AS708RB block diagram
Low-power sensors extend the battery life
of battery-operated medical devices. Signal-conditioning circuit AS7038RB provides a low-noise AFE for
The process of signal conditioning plays electrocardiogram (ECG) signal acquisi-
Biocompatibility a vital role in the amplification, filtra- tion and a low-noise optical front end for
Because many medical sensors are placed tion and processing of signals obtained blood-related measurement.
near the human body, biocompatibility from various sensors. This is particularly The AS7038RB uses algorithms to con-
is of the utmost importance. To prevent important in cases where sensor signals vert photoplethysmography (PPG) and
unwanted reactions, the components used are weak (small amplitude) or when ECG readings into digital high-resolution
in the building of sensors need to be made establishing connections with microcon- manometry, heart rate variability, contin-
of non-reactive and non-toxic materials. trollers (MCUs) and other processors. uous blood pressure and SpO2 values. In
This is a key consideration for wearable The proper functioning of obtained data addition, the detector provides interfaces
technologies that are intended to maintain relies heavily on the presence of analog for measuring skin temperature and skin
a continuous touch with the skin. front-end (AFE) circuits, which include resistivity using external sensors.
instrumentation amplifiers and filters.
Security and privacy These circuits are important in maintain- MCUs and processors
Because medical sensors produce sensi- ing the integrity of the data. MCUs and processors serve as the central
tive data about patients, it is necessary to For example, in a CGM device, an AFE processing units in medical equipment.
implement comprehensive data security is needed to interface with both the glu- Signal processing, data storage and con-
and privacy measures. Encryption tech- cose electrochemical sensor(s) and MCU nectivity with other devices or networks
niques, secure data transmission pro- unit, usually provided with some sort of are among the tasks that they undertake.
tocols and compliance with healthcare wireless connectivity, on which dedicated The selection of an MCU with adequate
data protection rules are all necessary for firmware is running. One example is the processing capabilities, minimal power
designers to implement into their prod- MAX30131 from Analog Devices Inc., consumption and the requisite interfaces
ucts to keep patient information from an ultra-low–power AFE IC designed to is essential to ensure the smooth func-
being accessed inappropriately or stolen. interface with electrochemical sensors. tioning of medical sensors.
In addition to high accuracy and
Key components in medical sensor design precision, achieved through up to four Wireless transceivers
While a medical device, comprised 12-bit voltage DACs, up to four 16-bit Enabling the real-time transfer of data and
of one or more sensors, may adopt an current ADCs and one 16-bit EIS ADC, facilitating remote monitoring, Bluetooth,
architecture specifically tailored for the MAX30131 features low current Wi-Fi and other wireless communication
IMAGE: AMS OSRAM
the application, a range of components absorption (3.5 μA), an SPI interface modules enable the smooth integration of
is required in most of these designs, and voltage monitoring for safety and healthcare systems, granting patients and
including signal-conditioning circuits, compliance in a small package. healthcare professionals immediate access to
processors and wireless transceivers. For vital sign sensing, the ams Osram vital data. ☐
ELECTRONIC PRODUCTS • electronicproducts.com • NOVEMBER/DECEMBER 2023
12 COVER STORY AI in Medical Imaging
A
rtificial intelligence and medical
imaging have combined to
create a revolutionary shift in
the field of medical diagnosis. Medical
imaging techniques, such as X-rays,
Figure 1: The Definium 656 HD X-ray system
magnetic resonance imaging (MRI)
and computed tomography (CT) scans,
are complemented and even super- health status. More precise and individu- company in the field of medical tech-
seded by AI. alized treatment plans will be impossible nology and diagnostics, has developed
In addition to improving diagnostic to achieve without the capacity to extract the Definium 656 HD, a fixed X-ray
turnaround time, this integration opens latent information from medical images. system (Figure 1) that provides several
previously inaccessible doors for tailored The algorithms that interpret intricate AI-based capabilities. Using 3D camera
medication. One major development is visual data are fundamental to AI in technology, GE’s Intelligent Workflow
the increased use of deep-learning algo- medical imaging. Continuous efforts to Suite is designed to produce more con-
rithms, which can sift through massive improve algorithmic precision, efficiency sistent images and eliminate the need
datasets in search of abnormalities and and interpretability constitute a key trend for retakes.
patterns, providing a higher degree of in this field. Convolutional neural net- The system incorporates Version 2.2
previously unavailable accuracy. works (CNNs) have been instrumental in of GE’s Helix AI-based advanced
Improving the precision and effi- image-recognition tasks, and their appli- image-processing software, which
ciency of image analysis is a major focus cation in medical imaging is becoming provides enhanced anatomic detail and
of current research in both AI and medi- more complex. clarity regardless of dose, patient position-
cal imaging. Radiomics is a new subfield Transfer learning, a technique in ing, field of view or metal implants.
of medical imaging that promises to which pre-trained models are adapted Siemens Healthineers AG, a pioneer
revolutionize the way data is extracted for specific tasks, is gaining popularity, in healthcare innovation, has developed
from medical images. enabling the development of AI sys- several digital applications based on AI.
In the past, doctors relied on skilled tems using relatively small quantities One technology is Deep Resolve, which
radiologists to spot abnormalities in of medical imaging data. As algorithms uses CNNs to speed up MRI scans (by as
imaging tests like X-rays, MRIs and CT become more refined, they improve diag- much as 70% in the case of brain imag-
scans. Diagnostic results are vulnerable nostic accuracy and help identify subtle ing) thanks to AI.
to human error and weariness. AI with patterns and anomalies that may elude The compromise between scan time,
deep-learning capabilities can tirelessly human observation. resolution and picture noise defines
study massive datasets and detect minute AI is not only being used to ana- MRI quality. To improve one of these
changes and irregularities that humans lyze and interpret images but also to factors, there likely will be a tradeoff.
might miss. streamline medical imaging procedures. Deep Resolve solves this challenge
IMAGE: GE HEALTHCARE
With radiomics, not only is the diag- Automating the scheduling of imaging by enabling doctors to select a much
nosis process sped up, but the potential analyses and maximizing the efficiency of shorter scan time without sacrificing
for error is also reduced, leading to better imaging equipment are two key use cases picture quality by decreasing noise and
patient outcomes. It also aids in gaining for AI algorithms. maintaining or improving resolution.
a more complete picture of a person’s GE HealthCare, a leading innovative Deep Resolve utilizes the raw data from
NOVEMBER/DECEMBER 2023 • electronicproducts.com • ELECTRONIC PRODUCTS
AI in Medical Imaging COVER STORY 13
ing data resources, MAIDA will be a chain reaction (RT-PCR). Sampling analyzing medical imaging data involved
sending massive datasets to a central
server, which presented problems with
latency and confidentiality.
To reduce latency and enable real-
time analysis, edge computing processes
data near its origin. In the field of
medical imaging, this entails embedding
AI algorithms within individual imag-
ing machines. This not only improves
the efficiency of healthcare delivery by
speeding up the diagnosis process, but
it also paves the way for point-of-care
Figure 3: AI models help precisely detect Covid-19 and other lung diseases. AI applications in which choices can be
made immediately. ☐
ELECTRONIC PRODUCTS • electronicproducts.com • NOVEMBER/DECEMBER 2023
14 FEATURE Circuit Protection Devices
C
ircuit protection devices are safety components that
are used in every electronic device and system, rang-
ing from the smallest smartphones and wearables to
high-reliability applications like automotive and data centers to
protect them from failure due to surge events and electrostatic
discharge (ESD) strikes as well as overvoltage, overcurrent and
overtemperature conditions.
These small, protective devices include ESD protection
devices like transient voltage suppressor (TVS) diodes and
arrays, surge protectors, fuses and circuit breakers. Over the
past year, miniaturization continued to be a key trend, partic-
ularly for TVS diodes, driven by a range of end devices from
wearables to automotive interfaces.
Circuit protection manufacturers have also focused on AOS’s AOZ8S207BLS-01 TVS diode
enabling these protective devices to withstand the harshest
automotive, industrial and avionics applications. Here is a typically a design tradeoff in competing devices. The TVS diode
selection of 10 circuit protection devices, introduced in 2023, has an ultra-low capacitance of 0.3 pF (typical), which ensures
highlighting these trends. They are not in any particular order. signal integrity by not interfering with or impeding high-speed
data communication, the company said.
Ultra-small protectors for mobile and wearables Other features include high peak pulse current (10.5 A typ-
One space-saving bidirectional TVS diode is the ical) and low clamping voltage (5.3 V), which protect I/O ports
D3V3Z1BD2CSP from Diodes Incorporated. It is designed to and their sensitive electronics from transient voltages, reduc-
protect high-speed data ports from both ESD strikes and surge ing the risk of electrical overstress damage from things like
events. The new TVS diode targets I/O ports in high- frequent hot swapping. The D3V3Z1BD2CSP complies with the
performance computing hardware, smartphones, laptops, tab- IEC61000-4-2 immunity standard, providing ESD protection
lets, computers, displays and gaming consoles. against ±20-kV air and contact discharges.
Diodes said the D3V3Z1BD2CSP does not compromise The D3V3Z1BD2CSP can be used to protect I/O inter-
on either surge protection or low input capacitance, which is faces, such as USB Type-C, DisplayPort, HDMI and SD Card,
IMAGES: DIODES INC. (LEFT); ALPHA AND OMEGA SEMICONDUCTOR LTD. (RIGHT)
with high-speed data rates up to 20 Gbits/s. It is housed in a
compact, 0.6 × 0.3 × 0.3-mm DSN0603 WLCSP. In addition,
the TVS diode features a wide operating temperature range
of –55°C to 150°C for protection in challenging application
environments.
Targeting ESD protection of USB4 and Thunderbolt 4,
Alpha and Omega Semiconductor (AOS) has developed a
TVS diode with an ultra-low reverse working voltage. The new
AOZ8S207BLS-01 delivers low capacitance, a fast response time
and small packaging.
The AOZ8S207BLS-01 features an extremely low capacitance
of 0.15 pF and claims “superior” high-speed data-line protection
thanks to the company’s advanced Ultra-Low Breakdown Voltage
TVS platform and innovative packaging. A low breakdown volt-
age is essential for ESD protection devices, AOS said.
The company also reported the AOZ8S207BLS-01 can
Diodes Inc.’s D3V3Z1BD2CSP TVS diode provide a faster response time compared with conventional
NOVEMBER/DECEMBER 2023 • electronicproducts.com • ELECTRONIC PRODUCTS
Circuit Protection Devices FEATURE 15
2022 as replacements for surface-mount metal oxide varistors Schurter’s FRM-A fuse holder and DRM-A SMT fuse
for household and industrial applications.
The high-power and low-capacitance PTA03-3.3ULC TVS The FRM-A has successfully passed vibration, shock and
hybrid array pro- salt mist tests according to NF C 20-7XX and IEC 60068-2-XX
vides low capaci- and is built to UL 4248-1 and CSA C22.2 No. 4248-1. The fuse
tance—max. 2.4 pF holder is developed exclusively for use with the SMT DRM-A
(I/O to I/O)—even ceramic fuse.
at higher tempera- The DRM-A is a fast-acting ceramic SMT fuse built accord-
tures and 2,000-W ing to UL 248-14 for avionics applications and uses gold plating
peak pulse power on the endcaps to prevent tin whiskers. It features a pre-arcing
per line (8/20 µs time rated for an altitude of 50,000 feet, but it is suitable for any
typical). It features application that requires a reliable and robust design. Rated
100 A (2/10 µs) per 0.5–8 A at 250 VAC and 125 VDC, the DRM-A meets similar
Bellcore GR1089 IEC environmental tests as the FRM-A, as well as additional
(intra-building) MIL-STD-202 tests.
and ESD protec- Used together or the fuse separately, the FRM-A and DRM-A
tion greater than devices can be used in a range of industrial markets, AV/IT appli-
30 kV, contact per cations according to IEC/UL 62368-1 and household appliances
IEC 61000-4-2. It ProTek’s TVS hybrid array according to IEC 60335-1. ☐
ELECTRONIC PRODUCTS • electronicproducts.com • NOVEMBER/DECEMBER 2023
18 PRODUCT ROUNDUP Capacitors and Resistors
B
oard space is always at a premium,
especially when it comes to passive
components. However, designers Murata’s LCC Series of LW reversed MLCCs
in high-reliability markets are looking for
more than just tiny devices; they also need and feature a reversed termination for same or smaller package sizes.
capacitors and resistors that can handle low ESL. Vishay Intertechnology Inc.’s new
higher operating temperatures and harsh In addition, the 1-µF capacitance in a series of low-impedance automotive-grade
environmental conditions. These include 0.5 × 1.0-mm footprint makes the parts miniature aluminum electrolytic capacitors
applications in automotive, avionics, the smallest in the market, Murata said. delivers higher performance in smaller case
industrial and telecommunications. The company attributes the smaller sizes than previous-generation solutions.
In many cases, passive component size to Murata’s proprietary thin-layer The Vishay BCcomponents 172 RLX series
manufacturers are doing more than just forming and high-precision lamina- features high ripple currents up to 4.9 A,
shrinking the package size. They are pack- tion technology, in combination with high-temperature operation to 105°C and
ing more performance in these tiny devices advanced material atomization and a useful life of up to 10,000 hours. They are
while providing higher reliability. In many homogenization techniques. The result available in 14 case sizes, ranging from
cases, higher performance enables is about a 20% reduction in component 10 × 12 mm to 18 × 40 mm.
designers to shrink their bill of materials. height compared with existing parts. The AEC-Q200–qualified capacitors
For capacitors, this means higher Murata said the smaller size allows the offer lower impedance and higher capaci-
capacitance/voltage (C/V) ratings in the capacitors to fit more easily on the backside tance for a given case size and voltage, as
same or smaller package sizes as well as of circuit boards. It also allows the parts to well as up to 54% higher ripple current at
lowering the equivalent series resistance be placed in optimum positions for decou- the same C/V rating in smaller case sizes,
IMAGES: MURATA MANUFACTURING CO. LTD. (TOP); VISHAY INTERTECHNOLOGY INC. (BOTTOM)
(ESR) and equivalent series inductance pling of processor power rails, close to the compared with previous solutions. The
(ESL). For resistors, this often translates die. This reduces the number of capacitors benefits for designers translate into fewer
into technological improvements to sim- required, thus saving cost and increasing components needed, increased design
plify design and higher power ratings in system reliability, the company said. flexibility and board space savings.
smaller packages, resulting in fewer com- The MLCC series features low ESR Key specifications include rated
ponents in the design and lower costs. and a reduction in ESL, which is reported voltages up to 50 V, a capacitance value
Here is a selection of capacitors and to reduce the high-frequency impedance range from 150 µF to 15,000 µF and low
resistors introduced in 2023 that meet of the capacitors. “This improves circuit impedance down to 0.011 Ω at 20°C. The
the growing demand for smaller packag- performance to meet the requirements of devices are charge- and discharge-proof
ing and higher performance in high- modern, low-voltage, compute-intensive
reliability markets. applications, such as automotive advanced
driver-assistance systems,” Murata said.
Smaller and higher-performance capacitors The LLC series complies with
Murata Manufacturing Co. Ltd. recently AEC-Q200 requirements. The operating
introduced the LLC series, claiming the temperature range is –55°C to 125°C.
smallest and thinnest 1-µF LW reversed Even the traditionally larger alu-
multilayer ceramic capacitor (MLCC) minum electrolytic capacitors are
for automotive applications. The available in smaller case sizes without
automotive-grade MLCCs tout the compromising capacitance density. This Vishay’s 172 RLX aluminum electrolytic
industry’s first 0.18-mm profile package includes delivering higher C/V in the capacitors
NOVEMBER/DECEMBER 2023 • electronicproducts.com • ELECTRONIC PRODUCTS
Capacitors and Resistors PRODUCT ROUNDUP 19
IMAGES: VISHAY INTERTECHNOLOGY INC. (BOTTOM, LEFT); KOA SPEER ELECTRONICS (TOP); STACKPOLE ELECTRONICS INC. (BOTTOM, RIGHT)
anti-surge thick-film power resistor in temperature range of –55°C to 155°C. thick-film resistors that aren’t suitable for
the 0805 case size with a higher power The power resistors are RoHS-compliant this application.
rating of 0.5 W. Applications include and halogen-free.
automotive, industrial, telecommunica- Packing more power in a smaller pack-
tions and medical. age size, KOA Speer Electronics recently
This AEC-Q200–qualified device introduced the UR73VH2B current-sense
lowers component count and placement resistor for automotive applications. The
costs. Case in point: With its increased AEC-Q200 resistor offers a higher power
power rating, the RCS0805 e3 can now rating of 1 W in a smaller 1206 package
be used in place of four standard par- size and extends the resistance range for
allel resistors in the 0805 case size, two the UR73VHB resistors.
parallel devices in the larger 1206 or one Key specifications include a resis-
resistor in the 1210 case size, Vishay said. tance range of 100 mΩ to 1 Ω, a TCR of
The resistor also offers “superior” ±100 ppm/°C and a standard tolerance
pulse-load performance and of ±1%. The resistor also offers a wide
electrostatic-discharge surge characteris- operating temperature range of –55°C
tics when compared with standard chip to 155°C, with a rated terminal tem- Stackpole’s RNCP chip resistor series
resistors for applications that are subject perature of 125°C.
to high and repetitive surge pulses, Delivering low resistance, high accu- The RNCP chip resistor series
according to Vishay. racy, high reliability and current detec- features high precision with tolerances
tion, the UR73VH2B resistors are suited down to 0.1% and TCR as low as
for automotive, industrial, telecommuni- 10 ppm, as well as anti-sulfur capabil-
cation and consumer electronics markets ity with shifts of less than 2% under
in a range of applications, including industry-standard EIA-977 testing,
electronic control units, small motors, according to Stackpole.
displays, monitors, DC-to-DC conversion Unlike thick-film resistors, the RNCP
and AC adaptors, power supplies, note- series does not require a lead-containing
book PCs, cellphones and motor circuits. dielectric glass, providing an RoHS-
Stackpole Electronics Inc. has compliant solution without exemptions,
Vishay’s RCS0805 e3 power resistor expanded its RNCP series of anti-sulfur the company said. ☐
NOVEMBER/DECEMBER 2023 • electronicproducts.com • ELECTRONIC PRODUCTS
Power NEW PRODUCTS 21
Medical buzzers meet alarm signal requirements The enclosures are available in four plan sizes, from
CUI Devices’ Audio Group has released a new line of medical 6.30 × 7.87 inches to 11.42 × 10.24 inches, in accordance with
buzzers that comply with the alarm signal requirements of IEC double and extended Eurocard-sized PCBs. The two standard
60601-1-8. The CPIM family is a range of piezo audio indicator heights are 2.88 inches and 4.82 inches. Optional side panels
buzzers that can produce low-, medium- and high-priority add 1.95 inches.
tones for general medical use Accessories include a sloping control panel, which creates a
as well as tones for desktop reading angle of 30° or a wall reading angle of 60°, and
specific medical an infill panel, which is needed for 4.82-inch–high cases with
applications, a sloping panel and allows for the mounting of connectors for
including ventila- probes and data cables. Other accessories include wall-
tor, oxygen and mounting brackets, side-panel connectors, stacking elements
cardiovascular for securing several devices and PCB mounting screws.
equipment. The MEDITEC enclosures are customizable. Services
Key features include built-in driving circuits, rated volt- include CNC machining, lacquering, printing, laser marking,
ages of 5 VDC, sound pressure levels of 90 dB at 10 cm, rated special materials, RFI/EMI shielding and installation/
frequencies of 4,000 Hz and an operating temperature range assembly of accessories.
from –30°C to 85°C. The models are housed in through-hole OKW Enclosures Inc.: www.okwenclosures.com
packages with 44-mm diameters and 10.25-mm profiles.
Four part numbers are available: CPIM-4410-80C (cardio-
vascular tone), CPIM-4410-80T (general tone), CPIM-4410-80V Image signal processor targets medical
(ventilation tone) and CPIM-4410-80Y (oxygen tone). Tones endoscopes
include silence (standby mode), low-priority alarm signal (two Omnivision has expanded its OVMed
beeps repeat every 20 seconds), medium-priority alarm signal family with the introduction of
(three beeps repeat every 10 seconds) and high-priority alarm the OH0131 image signal pro-
signal (10 beeps repeat every three seconds).
cessor (ISP) for reusable
The CPIM medical buzzers are available now with prices
and disposable endoscopes
starting at $11.73 each at 250 pieces through distribution.
connected to handheld tablet
Please contact CUI Devices for OEM pricing. Lead time is from
consoles or camera control
stock to 10 weeks.
units (CCUs). The ISP supports
CUI Devices: www.cuidevices.com
Omnivision’s medical image sensors,
up to 2-MP resolution, including the OCHTA, OVM6946,
Plastic enclosures target medical electronics OCHFA, OCHSA and OCH2B.
By providing the medical-grade image sensors with wafer-
OKW Enclosures Inc. has expanded its MEDITEC line of plas-
level optics along with the cable and ISP from one vendor, it
tic enclosures for desktop, portable and wall-mount electronics.
simplifies the supply chain for medical OEMs, Omnivision said.
Targeting medical electronics, the enclosure line is now avail-
able in two versions and four plan sizes. They can be specified The OH0131 ISP is based on an ASIC system-on-chip (SoC)
as separate components for individual configurations. for high image quality and high reliability as well as cost-
OKW said the MEDITEC line is designed primarily for effectiveness. It supports Omnivision’s proprietary AntLinx
high-quality, high-value healthcare and laboratory electronics. CMOS chip-on-tip endoscopy imaging interface and MIPI
It is also suited for feedback control, test and measurement, interfaces. It can integrate with any MIPI-input post-processing
communications and network technology, data collection, board by an SoC, FPGA or x86 platform to build custom CCUs
control peripherals, modems and interfaces. or handheld tablet consoles.
For robustness, the enclosures feature strengthening ribs at Omnivision said the OH0131 kernel features the latest state-of-
the top and base of the units. They come with clip-in side trims the-art image pre-processing algorithms that support brightness,
with or without ventilation to hide the fixing screws. Screw contrast, saturation, sharpness, hue, white balance and gamma
pillars are inside the enclosures for installing PCBs and compo- adjustment with advanced noise reduction. Post-processing per-
nents. Four screw-on, non-slip feet are included for stability in formed by a third-party partner using an SoC or FPGA can target
desktop applications. features like LED drivers, patient isolation, high dynamic range,
In addition, the enclosures are easy to assemble and can be image rotation, image mask/onscreen display, H.264 compression,
specified with or without a bail arm (accessory) that doubles as high-definition multimedia interface and Wi-Fi output.
a desk stand. This can be adjusted in increments of 30°. The OVMed OH0131 image signal processor is available
The MEDITEC line is molded from ABS (UL 94 HB). The now. The ISP will undergo IEC 60601 EMC and EMI pre-scan
standard color is off-white (RAL 9002) with either lagoon green or testing. The miniature board measures 63 × 51 mm.
case-colored side trims. Custom colors are available on request. Omnivision: www.ovt.com
NOVEMBER/DECEMBER 2023 • electronicproducts.com • ELECTRONIC PRODUCTS