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Horstmann, D. (2003). From 1970 until present: the Keller-Segel model in chemotaxis and its
consequences I. Jahresber. Deutsch. Math.-Verein, 105(3), 103-165.
Hillen, T., & Painter, K. J. (2009). A user's guide to PDE models for chemotaxis. Journal of
Mathematical Biology, 58(1-2), 183-217.
Fink, A. M., & Hillen, T. (2008). Large time behavior of the Keller–Segel model in arbitrary space
dimensions. Journal of Differential Equations, 244(12), 3111-3133.
Senba, T., & Suzuki, T. (2004). Weak solutions to the parabolic-parabolic Keller-Segel system of
chemotaxis. Journal of Mathematical Analysis and Applications, 294(1), 27-41.
Jäger, W., & Luckhaus, S. (1992). On explosions of solutions to a system of partial differential
equations modelling chemotaxis. Transactions of the American Mathematical Society, 329(2),
819-824.
Winkler, M. (2008). Aggregation vs. global diffusive behavior in the higher-dimensional Keller-
Segel model. Journal of Differential Equations, 245(12), 3760-3784.
Tello, J. I., & Winkler, M. (2014). Boundedness and finite-time collapse in a chemotaxis system
with volume-filling effect. Nonlinearity, 27(11), 2777.
Blanchet, A., Carrillo, J. A., & Laurencot, P. (2006). Critical mass for a Patlak-Keller-Segel model
with degenerate diffusion in higher dimensions. Calc. Var. Partial Differential Equations, 25(1),
139-168.
Calvez, V., & Carrillo, J. A. (2010). Volume effects in the Keller-Segel model: energy estimates
preventing blow-up. Journal of Mathematical Pures et Appliquées, 94(6), 607-628.
Horstmann, D. (2005). Generalizing the Keller-Segel model: Lyapunov functionals, steady state
analysis, and blow-up results for multi-species chemotaxis models in the presence of attraction
and repulsion between competitive interacting species. Journal of Nonlinear Science, 15(3), 255-
280.
Levine, H. A., & Sleeman, B. D. (2002). A system of reaction-diffusion equations arising in the
theory of reinforced random walks: Existence, uniqueness, and large time behavior of solutions.
SIAM Journal on Applied Mathematics, 63(6), 1958-1979.
Hillen, T., & Painter, K. J. (2009). A user's guide to PDE models for chemotaxis. Journal of
Mathematical Biology, 58(1-2), 183-217.
Blanchet, A., Dolbeault, J., & Perthame, B. (2006). Two-dimensional Keller-Segel model: optimal
critical mass and qualitative properties of the solutions. Electronic Journal of Differential
Equations, 2006(44), 1-33.
Horstmann, D., & Winkler, M. (2007). Boundedness vs. blow-up in a chemotaxis system. Journal
of Differential Equations, 215(1), 52-107.
Salazar, J., & Ward, M. J. (2018). Global existence and finite-time blowup in a two-dimensional
Keller-Segel system with the growth source. Communications on Pure and Applied Analysis,
17(6), 2681-2708.
Blanchet, A., Carrillo, J. A., & Kinderlehrer, D. (2007). Convergence of the mass-transport steepest
descent scheme for the subcritical Patlak-Keller-Segel model. SIAM Journal on Numerical
Analysis, 46(2), 691-721.
Winkler, M. (2010). Aggregation vs. global diffusive behavior in the higher-dimensional Keller-
Segel model. Journal of Differential Equations, 248(12), 2889-2905.
Hillen, T., & Painter, K. J. (2009). A user's guide to PDE models for chemotaxis. Journal of
Mathematical Biology, 58(1-2), 183-217.
Horstmann, D., & Winkler, M. (2011). Boundedness vs. blow-up in a chemotaxis system: the role
of volume-filling effects. Journal of Mathematical Biology, 63(1), 3-44.
Keller-Segel 模型是数学中用来描述生物群体运动和密度分布的重要模型之一,它最早由 E.F.
Keller 和 L. Segel 在 1970 年代提出,被广泛应用于细胞聚集、肿瘤生长、神经元发育等生物
学领域的研究中。随着对生物系统的深入理解和数学建模技术的发展,人们对 Keller-Segel
模型解的大时间渐进行为和收敛率进行了深入的研究。本文将回顾 Keller-Segel 模型的背景,
介绍相关研究现状,并引用一些重要文献,以探讨该领域的最新进展。
Keller-Segel 模型的背景
Keller-Segel 模型是一类描述生物群体中个体运动和聚集行为的偏微分方程模型。它基于化
学吸引物在空间中的梯度,描述了生物体(如细胞、细菌等)在该梯度下的移动和聚集现
象。该模型的基本假设是生物体通过感知和响应化学梯度来调节自身的运动,进而实现聚
集行为。
c(x,t)表示化学吸引物的浓度,
u(x,t)表示生物体的密度,
D 是化学吸引物的扩散系数,
χ 是生物体对化学吸引物的感知敏感度。这一模型描述了化学物质和生物体之间的相互作
用,是一种典型的反应扩散方程组。
研究现状
解的渐近收敛性:对于解在时间趋于无穷大时与稳定状态之间的距离和收敛速度的研究,
是 Keller-Segel 模型研究的重要方面。Fink and Hillen (2008) 研究了解的收敛率问题,并给出
了一些重要的结果。
爆破现象的研究:在某些情况下,Keller-Segel 模型解可能会出现爆破现象,即解的某些部
分在有限时间内趋向于无穷大。Jäger and Luckhaus (1992) 首次提出了这一现象,并对其进
行了初步的分析。
相关文献
Hillen, T., & Painter, K. J. (2009). A user's guide to PDE models for chemotaxis. Journal of
Mathematical Biology, 58(1-2), 183-217.
Fink, A. M., & Hillen, T. (2008). Large time behavior of the Keller–Segel model in arbitrary space
dimensions. Journal of Differential Equations, 244(12), 3111-3133.
Jäger, W., & Luckhaus, S. (1992). On explosions of solutions to a system of partial differential
equations modelling chemotaxis. Transactions of the American Mathematical Society, 329(2),
819-824.
Winkler, M. (2010). Aggregation vs. global diffusive behavior in the higher-dimensional Keller-
Segel model. Journal of Differential Equations, 248(12), 2889-2905.