Acid Prevention

Antacid, H2 Blockers & PPI

Antacid: MOA:
IT DOESN’T
S Sodium Bicarbonate (brand: Alka-selzer) Immediately neutralizes stomach acid, LAST LONG
but ONLY temporary (NOT long lasting)
C Calcium Carbonate (brand: Tums, Rolaids)

A Aluminum Hydroxide
HESI Question KEY POINTS & MEMORY TRICK
M Magnesium Hydroxide (brand: Milk of Mag)
Magnesium hydroxide
Anti –Acids
Side Effects: Can upset stomach +
Anti –MIXING with other MEDs
Liquid bowel movements
Aluminum & Calcium Magnesium ‘’mellow’’
Constipation = Diarrhea 1 hour BEFORE or AFTER
OTHER MEDs !

Al Gi
MILK OF
NOT for heart failure!
Mg
MAGNESIA
· Nothing OTC “over the counter”
Ca · Sodium = Swells

H2 Blockers: Indication: MOA:

GERD & Ulcers Reduces gastric secretions by

“-tidine”
(duodenal & gastric) prevention BLOCKING H20 receptors in H2
Ranitidine
(brand: Zantac)
the stomach
Famotidine Patient Education:
(brand: Pepcid)
KEY POINTS & MEMORY TRICK
• No over eating
• No stress/smoking 30 MIN BEFORE MEALS
• No NSAIDS + Asa - GI bleeds

RANITIDINE

NSAIDS
ASA

PPI: MOA:
P
P

Inhibits proton pump in the parietal cells of the P

Proton Pump Inhibitor

P

stomach to reduce gastric acid

P

“-prazole”
Omeprazole
Key Terms: KEY POINTS & MEMORY TRICK
(brand: Prilosec)

Esomeprazole
(brand: Nexium)

Pantoprazole
P P P P
Stress ulcer
prophylaxis
(brand: Protonix)
Prevents holes Porous Bones Possible GI infections
Prazole
“Stress ulcer prophylaxis” “regular bone density tests” “C-Diff”
in hospitalized
/surgical
Indication: patients

Stress ulcer prevention,

GERD, heart-burn