Professional Documents
Culture Documents
PAGE
Table of Contents
Physical Principles of Ultrasound 1 Module 1: Introduction to U.S., propagation of sound, binary numbers
9 Module 2: Decibels, power / intensity, sound tissue interactions, TGC
Brian Starkoff 21 Module 3: Basic transducer, pulse-echo imaging principles, bandwidth,
duty factor, intensity variation
These notes cover the principles of diagnostic ultrasound from 30 Module 4: Beam profile, side lobes, focussing, dynamic aperture
a basic background to more advanced theory. 38 Module 5: A-mode, B-mode, M-mode, line density, frame rate
45 Module 6: Resolution
During revision do not attempt to work your way through the 53 Module 7: Acoustic windows, real-time transducers,
material too quickly unless you are familiar with the content. A 62 Module 8: Signal pathways, scan conversion, analog-digital conversion
suggested schedule of study is included on the CD. 68 Module 9: Pre and post processing, measurements, quality control
79 Module 10: Imaging artifacts
91 Module 11: Doppler: Basic principles, continuous wave, pulsed wave,
colour Doppler, power Doppler
100 Module 12: Doppler controls, Doppler artifacts, Doppler quality control
Copyright © 2018, Brian Starkoff. Students and other persons studying ultrasound 111 Module 13: Contrast agents, harmonics, biological effects, recording
are licensed to use this program and files for personal study purposes only. methods, new / future developments
Copying (in whole or in part), use for any other purpose, or use by any other 125 Answers Answers to module questions and multiple choice questions
person is prohibited without the prior, express permission of the author.
132 Index
6.8 Ver.29
Study program
Week Study program
The following is a suggested
1 Module 1
Module 1
course of study leading up to 2 Module 2
the formal assessment on 3 Module 3
this topic. Start the course 20 4 Module 4 Topics:
5 Revision Modules 1 to 4
• Introduction to ultrasound
weeks prior to the final exam 6 Module 5
and set aside at least 2 7 Module 6
• Physics fundamentals
hours per week, preferably at 8 Module 7 • Wave physics
9 Revision Modules 5 to 7
the same time each week. 10 Module 8 • Propagation of sound
If there is less than the 11 Module 9
suggested 20 week time 12 Module 10
13 Revision Modules 8 to 10
• Velocity variation
frame then you will need to 14 Module 11
modify the schedule 15 Module 12
• Binary numbers
appropriately. 16 Module 13
17 Revision Modules 11 to 13
18 Revision Modules 1 to 7
19 Revision Modules 8 to 13
20 Final assessment
Overview: Terminology:
• Ultrasound is another imaging modality (like CT, MRI, An ultrasound image is described in terms of its echo
Nuclear Medicine, Angiography). characteristics:
Echogenicity - the brightness of the echoes.
• It is a method of producing images by interpreting
sound reflections (echoes) from the body. Where there are no echoes such as from the liquid in this
bladder, the area is called “anechoic” (no echoes).
The image is made up of a
mosaic of white or grey dots. Regions of low level echoes
Each dot represents an echo of (dark on the screen), are called
a structure in a patient. “hypoechoic” (low echoes).
Terminology: Overview:
Echotexture - the pattern of the echoes. • Ultrasound is an integral & important part of a
medical imaging department.
• Coarse or fine
• It is poorly understood by patients.
• Homogeneous
• The images are often poorly understood by
or Heterogeneous
Coarse referring doctors.
Fine
Sonographer Sonologist
A medical specialist (doctor)
A person trained and qualified in ultrasound. trained and experienced in ultrasound techniques and
He / she performs the examination and records the images in the interpretation of sonographic images.
(on films or recorded digitally). He / she interprets the images and provides a written report.
Sonographers may come from a variety of backgrounds:
- radiologist
e.g. - medical imaging As with sonographers, sonologists may -nuclear physician
- nursing sister come from a variety of backgrounds: - vascular physician
- obstetrician
- para-medical fields
- cardiologist
Sonographers have a high degree of decisional • In a general medical imaging department, a radiologist is
latitude in diagnosis. the most common person to undertake this role.
– They may make independent decisions of the • The sonologist / radiologist usually relies heavily on
course of the examination such as extending the the sonographer’s observations.
examination beyond the region requested. • Sonographers & sonologists work closely together.
B-Mode controls
Ultrasound equipment
Numerous controls are available for the
sonographer to produce the best possible image.
All imaging ultrasound
The list below has the more common ones:
equipment consist of three
basic components: • Power • Pre-processing
• Gain – dynamic range
1. Housing with electronics – edge enhancement
– Overall
and controls
– TGC – frame averaging
2. Monitor for display • Freeze – reject
– Hi Res Zoom
3. Transducer • Depth
• Post processing
• Callipers
– read zoom
? 4. Recording device • Frame rate /
- Separate or integrated – grey scale maps
resolution
Historical
Nature of Ultrasound
1880 Piezoelectric effect discovered by
Jacques & Pierre Curie
• Ultrasound is a form of energy consisting of - Certain crystals produce an electric potential
mechanically produced waves. when subjected to mechanical pressure.
• The frequencies are above the range of 1881 Reverse piezoelectric effect demonstrated
human hearing. - These crystals will expand and contract when
– (human hearing is in the range of 20 - 20,000 Hz) their faces are subjected to an electric potential.
Wave Physics
BASIC DEFINITIONS
There are two basic types of wave by which energy can
Two basic definitions related to ultrasound are: be transmitted from one point to another:
d -1 Electromagnetic waves
* Velocity v = t m.s (metres per second) - travel at the speed of light
P -2 - no medium is required for propagation
*Several
Intensity I = area W.cm (watts per square centimetre)
different metric measurement systems are
- distinguished by energy, frequency and wavelength
commonly used: Light and x-rays are electromagnetic waves.
CGS (centimetre / gram / second)
MKS (metre / kilogram / second) Mechanical waves
SI (Système International) Defined as the propagation of energy through a
In this course, the SI system will be used primarily. medium by cyclic pressure variations.
This is now the international standard in the - Need a deformable elastic medium for
science community and is a minor variation on the propagation (such as air, water, soft tissue).
MKS system.
Ultrasound propagates by mechanical waves.
time
T
T
VELOCITY ( v ) - Speed of the sound wave as
FREQUENCY ( f ) - Number of cycles that occur per it passes through the tissue
second
Frequency and period are related to 1 1 Average speed of sound in soft tissue (Propagation speed)
f = T or T = f
each other (as shown by the formula): = 1540 metres per second
If you know ‘f’ or ‘T’ then the other one can be calculated.
Conversely, with less compressible (stiffer) materials, increased compression = higher velocity
(e.g. bone) the sound transmits with higher velocity.
The increased speed of sound in more compressed
This property of the material is sometimes called its
material will become very important when harmonic
“stiffness”.
imaging is discussed in Module 13.
lighter molecules
Therefore sound will very often travel faster through
materials with heavy molecules (such as bone) because
they are much stiffer (or less compressible).
With lighter molecules the sound transmits with higher
velocity. Because they are light (therefore with less Also sound will very often travel slower through materials
inertia) the following molecule / cell moves away very with light molecules (such as air) because they are much
quickly under the influence of the preceding force. more compressible.
Introduction to the binary number system: Introduction to the binary number system:
Modern ultrasound machines use computers Similarly, the number 1,011 could be broken down
extensively for their operation. Because computers to its individual components. (Our brains, of
use binary numbers, and because a number of course, do this automatically because this is the
computer terms reflect this binary number system, system we have learned all our lives).
a basic knowledge of this system is required.
1011
This is a decimal number
(based on the power of 1251
3 2 1 0
10). Each column 10 1010 10
represents numbers with 3 2 1 0
increasing power of 10 10 10
10 10 1000 + 0 + 10 + 1 = 1,011
(from right to left)
1000 + 200 + 50 + 1 = 1,251
Introduction to the binary number system: Introduction to the binary number system:
15 2 3 + 22 + 21 + 20 1111 4 bit
number.
16
Intensity is related to loudness (in audio terms) In the following sequence, the ‘y’ axis
and to the strength of an echo (which relates to 14 shows the intensity of the received echo
the brightness of the echo on the screen) in from within the patient. The ‘x’ axis
INTENSITY 12 indicates the brightness of the pixel of
ultrasound terms.
mW cm
-2 light on the monitor (or in sound
10
applications, the loudness of sound that
8 your ear would hear).
For ultrasound, the ‘x’ axis also has a
6 grey scale bar which would show the
changes to the different degrees of
Intensity varies by very large amounts and in a 4 brightness on the display. Only six
non-linear fashion. shades of grey are shown.
2
1
1 2 3 4 5
BRIGHTNESS / LOUDNESS
16 16
Let us assume it requires an echo For the display to change to the next
14 14
intensity of 1 mW.cm-2 intensity to shade, the echo intensity must double
INTENSITY 12
produce a particular shade of grey. INTENSITY 12 (i.e. have an intensity of 4 mW.cm-2).
mW cm
-2
mW cm
-2 This is the way the sensitivity works with
10 10 our eyes (and our ears).
8 8
Then let us say that at 2 mW.cm-2
6 intensity, the pixel will change to 6
the next lightest shade of grey.
4 4
2 2
1 1
1 2 3 4 5 1 2 3 4 5
BRIGHTNESS / LOUDNESS BRIGHTNESS / LOUDNESS
And so on:
INTENSITY 12
8 mW cm
-2
10
6 8
4 6
The graph is
2 4
1 exponential in nature.
2
1 2 3 4 5 1
BRIGHTNESS / LOUDNESS
1 2 3 4 5
BRIGHTNESS / LOUDNESS
1 2 3 4 5 0
BRIGHTNESS / LOUDNESS
1 2 3 4 5
BRIGHTNESS / LOUDNESS
2 2 The log. of
It required an intensity of 2 mW.cm-2 to The next grey level 16 is 1.2
change to the next shade of grey. The log. required an intensity
of 2 is 0.3 of 8 mW.cm-2, the log.
1.5 1.5
LOG LOG
of which is 0.9
INTENSITY INTENSITY1.2
For the next grey scale
1 level, an intensity of 4 1 and for 32
0.9 it is 1.5
mW.cm-2 was required. The
0.6 log. of 4 is 0.6 0.6
0.5 0.5
0.3 0.3
0 0
1 2 3 4 5 1 2 3 4 5
BRIGHTNESS / LOUDNESS BRIGHTNESS / LOUDNESS
2 The relationship between the brightness and Power and amplitude also vary by very large amounts
the echo intensity is now linear. By using the and in a similar non-linear fashion.
logarithmic values, intensity and changes to
Therefore a new unit of measurement is required to
1.5 image appearance
can be directly related. consider these variations (for Power, Intensity or Amplitude)
LOG
INTENSITY1.2 The Decibel
1 The primary reason why decibels
0.9 are used for this type of
measurement is that this unit 1.5
0.6
0.5 automatically compensates for 1.2
0.3
relationships in this type of 0.6
5
1 2 3
BRIGHTNESS / LOUDNESS
4 scale changes on the images 1 2 3
BRIGHTNESS
4 5
2
THE DECIBEL THE DECIBEL
The Bel is the logarithmic ratio (to base 10) of the
relative intensity or power in two acoustic beams.
(The ’10’ indicates ‘to base 10”.
A decibel is 1/10 of a Bel. However it is often not used
because base 10 is assumed).
Logarithms:
Logarithms: Power Number Log 10
10 4 10,000 4
All logarithms in this course (and for most 10 3 1,000 3
mathematical uses) are to “base 10”. This means 10 2 100 2
that a logarithm is simply the number that 10 has 10 1 10 1
10 0 1 0
to be raised to, to get that number.
10 - 1 0.1 -1
e.g. 10,000 is the same as 104. This means that the 10 - 2 0.01 -2
logarithm of 10,000 is 4 10 - 3 0.001 -3
-4
10 0.0001 -4
Decibels vs. intensity of reflected wave Decibels vs. intensity of reflected wave
Intensity Intensity Intensity Intensity Intensity Intensity
change remaining in lost from change remaining in lost from
in dB reflected beam original beam in dB reflected beam original beam
0 dB 100% 0% 0 dB 100% 0%
-1 dB 79% 21% -1 dB 79% 21%
-2 dB 63% 37% -2 dB 63% 37%
-3 dB 50% 50% -3 dB 50% 50%
-6 dB 25% 75%
As the beam reduces in intensity, there is a -10 dB 10% 90%
significant difference between the two states (what
was sent out and what remains). When the beam When the beam has fallen to 10% of its original
has reduced to 50% of its original value, it can be value, there has been a -10 dB change.
calculated that there has been a -3 dB change.
Note that it is minus 3 dB because the beam has
become weaker (i.e. it has reduced in intensity).
Decibels vs. intensity of reflected wave Decibels vs. intensity of reflected wave
Intensity Intensity Intensity Intensity Intensity Intensity
change remaining in lost from change remaining in lost from
in dB reflected beam original beam in dB reflected beam original beam
0 dB 100% 0% 0 dB 100% 0%
-1 dB 79% 21% -1 dB 79% 21%
-2 dB 63% 37% -2 dB 63% 37%
-3 dB 50% 50% -3 dB 50% 50%
-6 dB 25% 75% -6 dB 25% 75%
-10 dB 10% 90% -10 dB 10% 90%
-20 dB 1% 99% -20 dB 1% 99%
When the beam has fallen to 1% of its original value,
it means that it has fallen another 10% of its Therefore for every -10 dB of change, the final
remaining value (i.e. 10% of the remaining 10%). value falls to a further 10% (or 1/10) of what
This means that there has been another -10 dB remained before.
change (making a total of -20 dB change).
Decibels vs. intensity of reflected wave Decibels vs. intensity of reflected wave
Intensity Intensity Intensity Intensity Intensity Intensity
change remaining in lost from change remaining in lost from
In dB reflected beam original beam In dB reflected beam original beam
0 dB 100% 0% -3 dB 50% 50%
-1 dB 79% 21%
-2 dB 63% 37% Note: • A -3 dB change means a 50% loss (i.e. the
-3 dB 50% 50% value falls to ½ the original value.
-6 dB 25% 75% • If the value decreases, the decibel change is -ve.
-10 dB 10% 90%
-20 dB 1% 99%
Question 15:
-30 dB
-40 dB If the received U/S beam is half the intensity of the
transmitted beam, what is the dB loss?
Question 14: Fill in the blank boxes
Dynamic range
Question 16: A term used to express a range of values.
In ultrasound, this is usually the maximum and
If a beam with initial intensity of 12 mW cm is minimum signal levels. - expressed in dB
reduced by 6 dB, what is the final intensity? May be used in different contexts in U/S:
1. The range of echoes able to be detected
100 mW.cm-2 by the transducer as variable output. 1V
You will need a calculator to do this problem
mathematically, however In the answer slides, there (In the example here, anything below 0.001
mW.cm-2 will not be detected, and anything
is an explanation on how to do this question very echo above 100 mW.cm-2 will simply produce Signal
quickly and without a calculator. intensity the maximum possible electrical voltage on levels
the transducer element).
0 V1 V1
1
Lower velocity
0 1
Lower velocity
angle of
incidence
angle of
refraction 0 2 0 2
V2 V2
Higher velocity Higher velocity
Sound-tissue interactions
Sound-tissue interactions
Refraction
o θ1 V1 Attenuation
When 02 = 90 , no sound is Lower velocity
Question 19:
Principal elements of attenuation
What is the attenuation (in dB) of a 4 MHz beam after it is
received back at the transducer after travelling to a depth Absorption
of 5 cm in soft tissue assuming total reflection? Depends on:
1. The material itself
Principal elements of attenuation
The echo returned back to the transducer is small, but echo The reflection from a specular reflector is very large but
detection is not dependent on the angle of the incident detection of the echo is highly dependent on the angle of
beam. In other words, the sound beam can strike the incidence. If the beam does not strike at close to 90o, the
surface at a wide range of angles and some echoes will still reflected echo will not travel back to the transducer (and
return to the transducer. will not be detected).
Z= v
where = density of a material
and v = velocity of sound in the material
( ) ( ) x 100
2 2
Water 1.48 Z2 - Z1 Z2 - Z1
Brain 1.58 R= or %R =
Blood 1.61
Z2 + Z1 Z2 + Z1
Kidney 1.62
Liver 1.65
Note: this formula is used for intensity changes. If
Muscle 1.7 amplitudes are being considered then the formulas to use
Bone 7.8 are:
Z2 - Z1 Z2 - Z1
R= or %R = x 100
Whenever an ultrasound beam strikes an Z2 + Z1 Z2 + Z1
interface between two materials with different
acoustic impedances, some sound is reflected This is because I A2.
and the remainder transmits through. (The same reason we have two decibel formulae)
Question 20:
Determine the percentage of the intensity of an ultra-
The fraction of sound transmitted through the interface sound beam that is transmitted from air into soft tissue.
can therefore be calculated: (Z soft tissue = 1.63 x 106 Rayls)
(Note: You will require a calculator for this question).
T=1-R or %T = 100 - %R What decibel loss of the intensity of the
Question 21: transmitted beam occurs at this air-soft
For example, if it was calculated that 0.8 (80%) of the
tissue interface?
sound beam was reflected, then 0.2 (20%) of the
sound beam is transmitted. Also keep in mind that the returning echo must cross
the same interfaces and suffers the same attenuation.
Note: It does not matter which interface is Z1 and which This this the primary reason that coupling gel is
one is Z2. (The same reflection/transmission will occur if required between the transducer and the skin. Even a
the beam comes from either direction). microfilm of air will reflect most of the sound entering
the soft tissue, and it will also reflect the same
percentage of echoes returning to the transducer.
Question 22:
Beam attenuation
A 5 MHz beam is transmitted into a body as demonstrated:
(a) What is the decibel loss of The ultrasound beam’s
the echo intensity intensity is attenuated at the
received by the 4 cm kidney rate of 1 dB.cm-1.MHz-1 in
transducer from the tissue (on average).
kidney / fat interface? 1 cm fat
Assume no losses at the bone Therefore the echoes
transducer-kidney interface.
returning from deeper
(b) If the initial (transmitted) intensity was structures become
3500 mW.cm-2, what is the final (received) intensity progressively weaker and
of the echo from the kidney / fat interface? weaker.
Assume no losses at the transducer / kidney interface.
patient
(Note: You will require a calculator for these questions).
gain
depth (time)
gain
depth (time)
Delay would be used when strong echoes from
superficial echoes are of no interest or superficial
depth (time)
artifacts are present and amplification of this superficial
Far gain is the amount of gain applied to the distant area would be detrimental to the image.
echoes.
References
Simple transducer
Physical Principles of Ultrasound Although the real-time transducers used with
Brian Starkoff modern ultrasound units are very complex (and
are covered in a later section of the notes), they
Module 3 all contain the following basic components:
Basic components
Topics: • Basic transducer
• Pulse echo imaging
• Duty factor
• Bandwidth
• Beam Intensity variation
Copyright © 2018, Brian Starkoff. Students and other persons studying ultrasound
are licensed to use this program and files for personal study purposes only. Case: • usually made of plastic
Copying (in whole or in part), use for any other purpose, or use by any other
person is prohibited without the prior, express permission of the author.
• robust
6.1 • sealed to prevent entry of fluids or dirt
+
- - - + + + The positive - - + + The heat is then
The material is +
- - ends of the - - + removed and the
+ -
then heated to a - + + +
- - - dipoles are - - + - material is
predetermined + + + +
- - - attracted to the - - allowed to cool.
temperature + + + - + + The dipoles
- - ++ negative electric - -
(called the “Curie + + + or magnetic field + - + + maintain their
temperature”) and - - -
+ + - - + + alignment under
- (and vice versa) + -
placed in a very - - + + so that the - - + + the continuing
+
strong electric or - - + - - -
+ + + dipoles align + + influence of the
magnetic field.
+ field.
+
- - + + themselves as - - -
+
-
- - +
+ + heat applied shown. - - -
+ +
-
MATCHING
LAYER
Unfortunately the damping material makes the A matching layer is placed immediately in front of the
transducer less efficient in transmitting and less piezoelectric element to match the acoustic impedances of
sensitive to the received echoes, however it is the element (Z = 30 x 106 Rayls) and soft tissue
essential to use for pulsed ultrasound. (Z = 1.6 x 106 Rayls).
+ +
Constructive interference
If the waves are the same frequency and 180o out of phase
(opposite phase), they will produce a wave with a lower amplitude
If the waves are both If one wave is positive and at the same frequency.
At any positive, they will add the other is negative their
given together to be a greater addition will be less than
instant: amplitude. This is
constructive interference.
either original wave. This is
destructive interference.
+
Destructive interference
PRP
P.R.P.
The pulse duration can be calculated by multiplying the number of
This time must be long enough to allow all required cycles in the pulse by the time for one cycle (the period of the
echoes to be received by the transducer. wave). i.e. PD = n x T
A pulse cannot be sent until all echoes from the preceding PD
• The Duty Factor is the fraction of time ie. DF =
pulse have returned from the required depth. PRP
that the unit is transmitting.
1
The PRP and the PRF are related by the formula: f =
T Typical duty factors in diagnostic ultrasound are 0.1% to 1%
(revise module 1)
1 (or 0.01 to 0.001 or 1/100 to 1/1000)
Therefore PRF = PRP and PRP = 1
PRF
If either the PRP or the PRF are known, then the (i.e., the PRP is about 100 to 1000 times longer than the PD)
other can be calculated.
PRP
The SPL is determined by the length of one cycle, i.e.
Continuous wave
the wavelength (which is determined by the frequency),
ultrasound has a duty
factor of 100% because it and the number of cycles in the pulse.
doesn’t have any ‘off’ time.
SPL = xn
I
I
Because of these variations, the beam’s measured
intensity will depend on when it is measured. 0
≈ 1 us time ≈ 1 ms
Three different time related intensity measurements The temporal peak intensity is typically 2 to 10
have been defined. times that of the pulse average intensity1.
( )
(c) Density 2
With transducers used for clinical ultrasound, the beam profile Beam profile
is also altered in the form of focussing. This is designed to
make the beam much thinner for better lateral resolution. One important aspect of a beam to always
keep in mind is the fact that an ultrasound
beam is 3 dimensional in nature.
without focussing
Remember, any part of the beam intercepting an
interface will return echoes.
with focussing
Note that the principles of near field length and far field
divergence are inherent even in focussed transducers and
therefore these principles still need to be understood.
Beamwidth Beamwidth
An ultrasound beam does not have a clearly Two common definitions are: (for intensity)
defined edge. 1. the 3 dB edge:
(the edge is taken as the point that the intensity of the
– the intensity decreases from the centre of the beam has fallen to ½ its maximum value – i.e. its
beam outwards intensity has fallen by 3 dB)
Question 29 I
side
lobes
I I I I I
1 2 3
Side lobes
cross-section
1 2 3
of beam
cross-section cross-section
of beam of beam
element
0 spacing
d
4. electronic
(with an array transducer) d
The most common technique in modern transducers
and will be described in more detail shortly.
A
Focal zone NOTE: The beamwidth formula also applies to the
slice thickness plane.
IDEAL ACTUAL
final signal output
However in reality, the wavefronts are curved
individual (radiating out from the point of echo origin). The
signals are
+ wavefront strikes the inner elements first, then the
added
outer ones progressively later.
signal lower voltage output
voltages
produced by + In the addition circuit, the
transducer signal voltages would be
elements. combined over a short but
WAVEFRONT significant period of time and
result in a lower amplitude
In an ideal situation, the wavefront of an echo would be voltage output.
WAVEFRONT
flat, and strike all transducer elements at the same time.
ACTUAL
+ +
This problem is
overcome by using the + DELAYS DELAYS
+
delay circuit to hold up
the inner element signals
by a predetermined DELAYS
amount. This allows the
outer element signals to
‘catch up’ and enables
the addition circuit to
produce a short high
amplitude output. The beamformer circuit adjusts the delays to suit required
distance that the echoes are coming from. This is done
WAVEFRONT automatically and continuously during receive.
(The machine knows the depth of the echoes from the
time delay after transmission).
It is possible to use multiple beamformers to obtain It is also possible to use multiple beamformers to transmit and
echoes from several different paths simultaneously. receive echoes from several different paths simultaneously in a
linear or curved array.
Beamformer 1
Beamformer 2
+ + Beamformer 3
DELAYS DELAYS
A-mode ultrasound
Although A-mode ultrasound is rarely used today, its A-mode ultrasound
principles of operation are the basis of diagnostic
ultrasound, and therefore should be understood.
The pulse strikes an interface in
transducer the patient and returns an echo.
C.R.O. screen
structure in
the patient Because the echo has not
yet reached the transducer
to be detected, no signal is
This signal is registered registered on the C.R.O. as
on the C.R.O. screen as a the trace continues to move
A pulse of sound is emitted deviation in the trace line. across the screen.
from the transducer.
A-mode ultrasound
A-mode ultrasound
The second echo reaches the transducer and the
signal generated is shown on the C.R.O. screen. This is what a trace would look like on an oscilloscope.
The two echoes have been
demonstrated on the C.R.O. screen.
the trace is known) and therefore the The trace shows the strength of the
distance between the interfaces in signal on the y-axis and time on the
the patient can be calculated. x-axis (from which the depth of
vt time
(d = 2 ) echoes can be calculated).
With B-mode ultrasound, the direction of the path of the As the beam path is altered at the transducer, the image
beam is known. This directional information is passed to the memory trace path is altered so that successive sets of
image memory and the echoes are displayed along this echoes can be displayed in their correct relative positions.
known path.
The brightness of each dot is relative to the strength of the If the echoes from each beam path are retained on the
echo. screen, an image is built up by the multiple beam paths.
+ +
If subtle shadowing
or enhancement is
Because it takes significantly longer to produce a suspected or being
single frame, more complex electronics are required searched for, compound
depth
time
On the monitor, the echoes from this beam path are
moved across the screen causing the echoes to trace Now when the echoes are moved across the screen, the
out a series of lines. moving echoes trace out wavy lines.
If there is no movement of the interfaces, these lines The display indicates depth on the y-axis, and time on
would be straight. the x-axis. Both these can be measured very accurately.
High frame rates are important for imaging rapidly (d) What is the maximum possible frame rate?
moving structures. Frame rate can also be calculated directly using the formula:
770
Frame rate depends on: Frame rate = N x D Where: N = number of lines
D = depth of view (in metres)
- the number of scan lines in each frame
Another useful formula relates frame rate to PRF:
- the time required for each scan line PRF = frame rate x number of lines
Now you can do this problem using the frame rate formula: Frame rate is also affected by:
Frame rate can be increased by: Frame rate can be increased by:
• Decreasing the number of scan lines.
• Decreasing the scanning depth. With fewer scan lines, less time is taken to produce the
entire frame.
With reduced depth, the ‘wait’ time between This can be accomplished by:
pulses does not have to be as long, therefore (a) Decreasing the width of the F.O.V. (field of view)
it takes less time to record each line.
Real-time imaging
Frame rate can be increased by:
• Decreasing the number of scan lines. If the maximum depth of the image is increased:
With fewer scan lines, less time is taken to produce the • The image will extend over a greater depth.
entire frame. • The line density will remain the same.
This can be accomplished by: (However with a sector or convex transducer, the line
density in the far field decreases with increasing depth).
(c) Decreasing the number of focal • The P.R.F. will be reduced.
zones (if using multiple focal zones).
• The frame rate will be reduced.
(Each focal zone is equivalent to another scan line).
(d) Using the write zoom feature (described in module 9). More anatomy will
This reduces the scanning depth and the field of be seen, but the
view width. frame rate is
compromised.
Either Or
• The line density will remain the same • The line density will increase
– spatial image quality will remain the same – spatial image quality will increase
and and
• The frame rate will increase • The frame rate will remain the same
– the temporal resolution will improve which will be
Which of these two options will occur will depend on the
good for rapidly moving structures.
brand / model of the machine itself.
Copyright © 2018, Brian Starkoff. Students and other persons studying ultrasound • greyscale resolution • temporal resolution
are licensed to use this program and files for personal study purposes only.
Copying (in whole or in part), use for any other purpose, or use by any other
person is prohibited without the prior, express permission of the author. • colour resolution
5.9
d
interface 2
Pulse continuing
Second echo to deeper tissues.
being reflected
The pulse has now completely The echoes from the two
In this second
passed through the first interfaces are now
example, the interfaces
interface and the echo from returning to the
are now separated by
this interface is traveling back transducer, however
one half the spatial
to the transducer. However the there is now no clear
pulse length start of the echo from the separation between
second interface is at the same them.
point as the end of the first
d echo.
d/2
At this point the pulse is just
making contact with the
second interface, but is only
½d half way through the first
interface.
256
squares (pixels). The number 20cm
depends on the scan resolution.
converter’s memory size.
However in the case of a 256
square matrix with the depth of
field set at 20cm, each pixel
(Scan converters will be discussed would represent 0.78mm.
in more detail in module 8).
In this case, the number of available pixels restricts
the axial resolution to 0.78mm.
256
20cm
512
The greater the number of pixels, the better the Using write zoom to expand a smaller area of
potential resolution (although it can never be better anatomy over the full storage matrix.
than the spatial pulse length restriction).
(Write zoom will be discussed in module 9).
As soon as an edge of
the beam intercepts a
reflector, it will
commence returning
an echo back to the
These two These two transducer.
structures are structures are not
clearly resolved resolved
In this second example, the two reflectors are closer The beam is now just intercepting both reflectors.
together (same distance as the beamwidth). Again, an Therefore an echo will continue to be received by the
echo will be returned from each interface while being transducer during the beam’s passage across both
intercepted by some part of the beam. reflectors.
5 or 4
better potential
lateral resolution
6
10 7
cm cm
Lateral resolution is always worse than axial resolution. (The length of the line equals
the width of the beam).
Question 31:
Question 33:
Write down at least five
factors that determine Calculate the best theoretical axial and lateral resolution
lateral resolution: in soft tissue of a 3.5 MHz transducer with a 2 cm
diameter active face which has 4 cycles in each pulse
Hint: and has an 8 cm focal depth.
You may need to revise the section on beam profile / beam (Note: You will require a calculator for this question).
width in module 4.
4. Which operator control affects frame rate? 6. If the number of cycles in the transmitted pulse is increased:
(a) Receiver gain
(b) Transmit power (a) Axial resolution is degraded
(c) Scan depth (b) Lateral resolution is improved
(d) Time gain compensation (c) Spatial pulse length is reduced
(d) Rate of attenuation is increased
bladder bladder
uterus uterus
Water in the stomach displaces the stomach gas
and adjacent bowel to allow visualisation of the
ovaries ovaries
pancreatic tail.
ribs
heart heart
• Aqueous and
vitreous humour
- eye structures
(e.g. retina)
• Amniotic fluid
– for the developing foetus
1. Sector 2. Linear
However please note:
The mechanism by
which the beam is Although not specifically mentioned here, it should be
steered or directed remembered that these transducers inherently still
to the different have the various components of a basic transducer
beam paths can be (described in module 3) such as a sealed case,
3. Convex 4. Radial damping material, electrodes, matching layer/s.
either:
When electronic
electrical pulses
steering is used,
If all the electrical the elements are
pulses are sent energised from one
to the transducer side of the group to
elements at the the other in In this case the right
same time, all sequence. hand element will be
the elements’ (Only very short energised first,
wavelets would delays are used – followed by the one to
emerge the time separation its left, and so on.
simultaneously being in the
and form into a nanosecond
beam as shown. range).
However they
will be close
A sound beam will
enough to join up
always travel at 90o
to form a single
to its wavefront.
wavefront.
The wavefront will therefore be angled In this case the beam
from the transducer face, the specific will travel towards the
angle being dependent on the original left of the screen.
time delays of the electrical signals.
PZT
0.1 – 0.3 mm 5 – 10 mm elements
0.1 – 0.3 mm 5 – 10 mm
PZT
elements • Each element is individually wired and is
electrically and acoustically insulated from its
adjacent elements (as with all array transducers).
• The transducer is composed of a large number (64
to 256) of small piezoelectric elements arranged
beside each other in a linear format.
• Each element may measure 0.1 to 0.3 mm wide by
5 - 10 mm long
If a single element only was pulsed, the near In this example, only 5 elements are
field would be very short and the angle of shown producing each beam for clarity,
divergence in the far field would be large. This however up to 128 elements could be
type of beam profile would not be practical. used for each pulse2.
You may like to revise the beam profile section of your
notes (in module 4).
rotating mirror
Copyright © 2018, Brian Starkoff. Students and other persons studying ultrasound - post-processing
are licensed to use this program and files for personal study purposes only. (occurs after storage)
Copying (in whole or in part), use for any other purpose, or use by any other
person is prohibited without the prior, express permission of the author.
6.1
This is a basic block circuit diagram of a diagnostic Start with the transducer that you hold in your hand, and
ultrasound unit. Although it appears complex, the following the image that you see with your eyes.
slides will take you through each main component.
scan
demodulation converter
image
memory display
amp. pulse
generator
display transducer A pulse generator initiates the signal that is sent
amp. pulse to the transducer to excite the PZT element.
generator The pulse generator is simply an electronic circuit that produces
recorder
beam small electrical voltages at regular intervals. The rate that the
tracking pulses are produced (the PRF) will be determined by the depth
transducer of the field of view.
(Revise pulse-echo imaging principles in module 5)
The pulse generator also links with the The pulse sent by the pulse generator is quite
scan converter (the main image data small (too small to energise the PZT element),
storage device). The scan converter needs therefore it is amplified significantly before being
to know when the pulse is being sent so sent to the transducer. scan
that it can place each echo at the correct scan converter
converter (amplifiers are used throughout image
depth location in the image image the overall circuit) memory
memory. memory
display
display
amp. pulse
pulse
generator
generator
Module 8 Page 62
Brian Starkoff
Physical Principles of Ultrasound
When an echo is received by the transducer, a small The signal then goes through a demodulation process
electrical signal is produced by the PZT element. (described in the next module’s notes) in which the signal
is changed into a single voltage spike which is then
Because the signal generated by the transducer is
passed to the scan converter image memory.
very weak, it is amplified (by a large amount).
scan
converter scan
image demodulation converter
memory image
amp. memory
amp.
display
display
amp. pulse
generator amp. pulse
generator
Note that at this stage the signal consists of
a small number of high frequency cycles.
(You may wish to revise basic transducer
transducer operation in module 3). transducer
A beam tracking circuit determines the beam path An output is available for the final image to be
direction along which the pulse is transmitted (and directed to the display and a recording device (e.g.
received). laser camera, video recorder, etc.).
scan scan
demodulation converter demodulation converter
image image
memory memory
amp. amp.
display display
amp. pulse amp. pulse
generator This information is generator
recorder
beam passed to the scan beam
tracking converter so that the tracking
echoes are stored in
transducer the image memory in transducer
the correct position.
The main control inputs are indicated as follows: Overall gain is an adjustment of the receive amplifier.
Power is an adjustment of the transmit amplifier. It It controls how much the echo signal is amplified.
controls the signal voltage received by the transducer Note: it has no effect on the transmit pulse intensity.
element and therefore the pulse intensity.
scan scan
demodulation converter gain demodulation converter
image image
memory memory
amp. amp.
power power
display display
amp. pulse amp. pulse
generator generator
recorder recorder
beam beam
tracking tracking
Increased power causes
transducer increased dose to the patient. transducer
Module 8 Page 63
Brian Starkoff
Physical Principles of Ultrasound
Relationship between Power and Gain Time gain Compensation adjustment is made in the
receive amplifiers. It has an input from the pulse
Both power and gain will affect the amplitude of the generator because the automatic increasing of the gain
signal of the echo stored in the image memory (and must be started at the time of pulse transmission.
therefore how bright the echo is shown on the image.
Power will alter pulse intensity and echo intensity. gain demodulation scan
converter
Increased power will increase penetration to deeper
tissues but it will increase the dose to the patient. amp. TGC
Gain will affect the signal of the echo only. Increased power
gain will not affect the dose to the patient. display
amp. pulse
If power is reduced, the pulses are less intense which generator
results in less intense echoes. This can be compensated recorder
beam
for by increasing overall gain but the signal to noise ratio tracking
is reduced (causing more noise on the image). This can (Revise TGC principles in
module 2).
lead to reduced image quality. transducer
11 110
11
101
10 100
10
011
01 010
01
001
00 000
00
Module 8 Page 64
Brian Starkoff
Physical Principles of Ultrasound
NOTE: If an analog monitor is used for display, • The scan converter changes the co-ordinate system image
(i.e. using X-Y co-ordinates) into a television type signal.
digital to analog conversion (which converts
digital signals back to analog signals) must take • It does this by storing the image data in the image memory
place before the video signal is passed to the in the X-Y format of acquisition, and then reading or
monitor. scanning this image data in a raster format used by a
television system.
(Most modern machines now have digital monitors).
see next slides
Module 8 Page 65
Brian Starkoff
Physical Principles of Ultrasound
Module 8 Page 66
Brian Starkoff
Physical Principles of Ultrasound
Question 35:
What is the maximum number of
1
pixel values (shades of grey) that: 0
1
0
(a) a 4 bit system can store?
(b) an 8 bit system can store? 1
to TV system
0
1
0 • After storage, the memory contents are
output in sequential fashion to a TV system.
This is the scan conversion process.
3. Dynamic receive focussing uses: 5. The ability of an ultrasound machine to demonstrate rapidly
(a) Mechanical means to focus the beam moving anatomy is associated with:
(b) Time delays to excite the transducer elements (a) Pulse duration
(c) Delay lines after the echoes are detected in the transducer (b) Transducer frequency
elements (c) Output power
(d) Variable number of elements to form the pulsed beam (d) Frame rate
4. Television frames are displayed at a rate of frames 6. Which control allows variable amplification of echo signals
based on reflector depth?
per second in a PAL non-interlaced monitor:
(a) 25 (a) Overall gain
(b) 50 (b) Scanning depth
(c) 100 (c) Time Gain Compensation
(d) 625 (d) Dynamic range
Answers to these questions are at the end of the notes.
Module 8 Page 67
Brian Starkoff
Physical Principles of Ultrasound
Pre processing
Physical Principles of Ultrasound There are a number of steps that the signal from the
Brian Starkoff transducer must go through before it is able to be
passed on to the scan converter memory:
Module 9 • Amplification • Edge enhancement
– overall gain and TGC • Frame averaging
Topics: • Signal processing • Compression • Smoothing
- pre processing • Demodulation • Reject
- post processing • Analog-digital conversion • Write zoom
• Measurements • Interpolation
• Quality Control
Once these pre processing steps have been carried out
Copyright © 2018, Brian Starkoff. Students and other persons studying ultrasound
are licensed to use this program and files for personal study purposes only. and the image data have been stored in the image
Copying (in whole or in part), use for any other purpose, or use by any other memory, the processing cannot be undone. The patient
person is prohibited without the prior, express permission of the author.
6.4
would need to be rescanned to make any changes.
Amplification Amplification
There are a number of separate
amplifiers which act on the signal. Note: Thanks to the improved electronics and
computing power, some machines have overall
The initial amplifiers are radio frequency amplifiers, i.e.
gain and TGC as post processing controls.
they act on the very high (MHz range) frequencies.
These include: - This means that these adjustments can be
scan
demodulation converter
image
made after the image has been frozen.
- Pre-amplification – TGC
memory
amp.
usually immediately at the
transducer connection or in pulse
display
amp.
the transducer itself. generator
recorder
beam
- T.G.C. transducer
tracking
- Overall gain
Compressed
0 When the dynamic range is increased (widened):
1 10 100 1000 10000
(stored) value
Question 37: Signal level More low level signals are visible on the screen.
The displayed image appears with lower contrast.
What would an image look like if this setting was Contrast resolution is reduced.
possible?
Demodulation
The signal then goes through a step (circuit) to
change each echo (which contains several cycles (a) Rectification: - the negative
at a high frequency) into a single voltage spike parts of the signal are
which is the type of signal suitable for storage. removed.
This step is called demodulation.
(b) Enveloping: - the high frequency components are
demodulation scan removed.
converter
image
memory
amp.
clock
display
pulse
The echo signal has now been
amp.
generator
recorder converted from several high
beam
tracking frequency cycles to a single
voltage ‘spike’.
transducer
• Edge enhancement
• Edge enhancement
The sequence of slides in the computer files demonstrates
Designed to emphasise the change in signal
how the process may take place.
levels across an interface.
Although you are not required to remember the level of
detail that is contained in the sequence, it is recommended
that you look at the slides to give you an idea of how the
original edge enhanced machine is able to manipulate the images.
The process uses a kernel (a mathematical You need only know that edge enhancement exaggerates
process) on each pixel value. the brightness change across boundaries and that the
It makes the edges of structures look ‘sharper’ on computer accomplishes this by applying a mathematical
formula to the pixels along each beam path in a frame.
the image.
Frame averaging
• Image updating
As each new frame is acquired, the values of frame
each pixel in the image memory are replaced by 1 With frame averaging,
new values: each pixel is looked at
BUFFER 80 in turn, but with this
process it is compared
either:
with the same pixel
as an absolute new value location from a
as an average of the new value and that previous frame (or
or frames).
of the same pixel in a previous frame (or
number of frames). Of course this means that the image memory storage must
be very large – multiple frames must be held in a temporary
- called frame averaging storage area (called a ‘buffer’).
(sometimes called persistence)
In the example here, a value 80 is stored in a particular pixel.
frame frame
1 2 BUFFER 80 88 81
In the following
frame, the same pixel
BUFFER 80 88 now is assigned a Here,the pixel value has been averaged
value of 88. (If this over three frames rather than two. 83
was presented FINAL IMAGE
directly to the screen, Frame averaging is designed to reduce speckle, however
84
the pixel might be the image may appear to ‘smear’ on the screen because
FINAL IMAGE very slightly brighter). some previous frame data are still being presented.
The computer has now averaged the two values of this
Note: Although it gives the appearance that the frame rate
pixel and calculated a final value of 84. This value is has dropped, the actual frame rate does not change.
the one that will get used for the final image. However there is a loss of temporal resolution.
• Smoothing
Each pixel value is averaged to some degree with the • Reject (also called ‘threshold’ or ‘suppression’)
surrounding pixel values (using a mathematical process
similar to that demonstrated in edge enhancement). – Signals below (or above) a certain level are
discarded.
50 40 30 20 10 50 40 30 20 10
40 50 40 30 20 40 47 40 30 20 Signal
Final
image level
30 40 50 40 30 30 40 50 40 30
20 30 40 50 40 20 30 40 50 40
Reject level Time / depth
10 20 30 40 50 10 20 30 40 50
• Write zoom 2 cm
2 cm • Write zoom - overview
– Image magnification technique applied during
acquisition.
Post-processing
• Write zoom - overview This processing occurs after the data have been
– The entire storage matrix is used for a stored in memory.
reduced anatomical area.
* therefore pixel resolution improves. The stored data remain intact and can be re-
accessed at any time.
Note that spatial resolution cannot be improved
beyond that inherently available from the beam Common post processing functions are:
geometry and spatial pulse length. • Read zoom (or Post-processing zoom)
• Post processing curves (grey scale mapping)
– Frame rate will improve because of the
reduced depth and width of the field of view
(i.e. temporal resolution will improve).
Note: Thanks to the improved electronics and
computing power, some machines have overall
gain and TGC as post processing controls.
PIXEL SIZE = 4.0 mm PIXEL SIZE = 4.0 mm PIXEL SIZE = 1.4 mm PIXEL SIZE = 4.0 mm
Each pixel now appears larger on the screen, however
the (anatomical) resolution of each pixel is unchanged. The comparison between read and write zoom is shown.
brightness
• A linear map is one in which the levels of grey are • This allows slightly different echo levels to be
spread equally over values. displayed separately in this low level range (at the
expense of the high level range).
black
black
0 128 256 0 128 256
Pixel value Pixel value
• A number of different curves are available on most
units.
With this feature, a selection of colours is available to
The sonographer must choose the curve that best
choose from.
suits the clinical situation.
Measurements
Measurement calculation
As with the pre-processing controls, when you • As each pixel represents a set spatial size,
get the opportunity, experiment with different distances can be accurately measured by
grey scale maps and B-colour settings on the counting the number of pixels between points
ultrasound machine and see what difference and multiplying them by the size each pixel
each setting makes to the image. represents.
X
Test object or phantom Image
In this case poor registration is demonstrated. Test object or phantom Image
Observe that the point reflectors are imaged as short lines Check depth of shallowest wire clearly visible
(equal to the beam width) at 90o to the beam path.
(Determination if it is really a
dead element problem or
Image
poor contact is discussed in
Module 10 under ‘equipment
Phantom Image related artifacts’).
Image
This is the deep
slice thickness plane edge of the beam. This is the type of image you
would see.
Note:
You may wish to revise your module 7 notes on how
transducers are focussed in this plane. Slice thickness is estimated by the thickness of the echo band.
Artifacts Artifacts
Assumptions of ultrasound:
• The pulse-echo beam travels in a straight line. Sound interaction related artifacts
-1
• The speed of ultrasound is constant at 1540 m.s . This is the most common group and will be
• The rate of attenuation through tissue is constant. described in detail in this module.
or: The strength of the echo is directly related to the
reflectivity of the reflector. • Enhancement • Refraction
• All echoes originate from the centre of the beam path. • Shadowing • Speed of sound
• Sound beams travel directly to a reflector and back to the • Anisotropy • Mirror
source. • Repeat echo • Speckle
• All echoes originate from the most recently transmitted • Side lobe • Range ambiguity
pulse.
• Beam width • Near field artifact
There are many instances in ultrasound where these
• Slice thickness
assumptions are incorrect – and this causes artifacts.
Artifacts - Enhancement
Artifacts - Enhancement
Enhancement is most commonly seen behind fluid filled
This is an area of increased echo brightness distal structures such as cysts or a full bladder.
to structures that attenuate the sound beam less It occurs because the beams of sound which pass
than the surrounding anatomy. through the fluid are not attenuated as much when
less sound they are actually in the fluid. (fluid has a lower
Increased
attenuation attenuation coefficient than average soft tissue).
brightness
less sound
attenuation
You might want to revise
Increased your notes on
brightness attenuation coefficients
in module 2 and note the
attenuation coefficient for
Area of enhancement water compared to soft
behind a cyst tissue.
Module 10 Page 79
Brian Starkoff
Physical Principles of Ultrasound
Artifacts - Enhancement
Artifacts - Enhancement
Enhancement can be very useful because it indicates
The pulses of sound emerging from the back of the properties about the type of material in the structure.
fluid (circled) are slightly more intense than those
- it suggests that the
passing through soft tissue only in the adjacent beam
material is fluid.
paths.
Enhancement is used as a
Therefore the echoes diagnostic criterion for cysts.
less sound
attenuation produced by these
Increased
pulses will also be Some solid lesions will also
brightness
slightly more intense produce enhancement if they
contain low attenuating tissue
which means that
(e.g. fat).
they will be brighter
on the screen.
X However useful information (such as a small lesion) may
be obliterated because of the overbright echoes deep to
the structure.
Module 10 Page 80
Brian Starkoff
Physical Principles of Ultrasound
If the returning echo is strong, and it strikes another If this happens, then the reflected echo is like another
good reflector on the way back (in this example it is the pulse. When it strikes the interface again, it will send
transducer-skin interface) then a reasonable amount of another echo back to the transducer.
this echo will then reflect back down into the patient. Although this echo will be weaker than the first one, it
may still be quite detectable.
echo reflecting back down 2nd echo from the same interface
display display
Module 10 Page 81
Brian Starkoff
Physical Principles of Ultrasound
When the second echo is detected by the transducer, This process can sometimes repeat itself several
the electronics interpret this as an echo coming from a times before the strength of the echo falls to a level
deeper interface (because it arrived at a later time). This which cannot be detected.
echo therefore shows on the screen as a deeper
These echo paths are shown side by
interface (because it was detected at a later time). side for clarity. Keep in mind that they
2nd echo from the same interface are actually in the same beam path and
therefore one on top of the other.
display
display
Module 10 Page 82
Brian Starkoff
Physical Principles of Ultrasound
Artifacts Repeat echo – Comet tail Artifacts Repeat echo – Comet tail
Module 10 Page 83
Brian Starkoff
Physical Principles of Ultrasound
Theory 1 Theory 2
When the sound pulse hits the
Under the influence of the
gas bubbles, it causes them to
sound pulses, a pocket of fluid
resonate1 (strongly vibrate at a
trapped between a group of
specific frequency). These
closely located bubbles
vibrations send compression
vibrates2,3, and in a similar
waves back to the transducer
manner to the bubble
which are interpreted as
resonance theory, the
repeated echoes.
vibrations send compression
This artifact is, therefore, waves back to the transducer
sometimes known as and are interpreted as echoes.
“Resonance”.
Keep in mind that when any part of the sound Any reflector within the beam can cause an echo to be
beam strikes an interface it can return a placed on the image along the beam path. So if the edge
detectable echo. of the beam intersects a strong reflector, an echo will be
returned – and, if strong enough to be detected, it will be
placed along the central axis of the beam.
Module 10 Page 84
Brian Starkoff
Physical Principles of Ultrasound
As mentioned in module 4, the beam has off axis Any echo received by the
sound. However these side lobes are much transducer is placed
weaker (less intense) than the main beam and along the central axis of
usually do not create significant echoes. the beam (where it
assumed the echo came
However if one of from).
these weak off axis
beams strikes a
strong reflector, it Here, the posterior wall
could return an echo
of the bladder is
strong enough to be
reproduced in the
detected.
bladder lumen.
It is important to remember that an ultrasound beam The result is that when the beam is through the
is three dimensional (i.e. it has thickness). structure (say a small cyst), there might also be
echoes of the soft tissue present on the image
Also remember that any structure within any part of
causing the cyst to contain echoes.
the beam can return a detectable echo.
As the beams move across
a structure building up a
frame, any part of a beam
outside the structure may
still return echoes which
can be detected.
The echoes could well come
from the adjacent soft tissue.
These internal echoes are There is another example (of a breast cyst) in the
caused by tissue beside the vein. computer file.
Module 10 Page 85
Brian Starkoff
Physical Principles of Ultrasound
The assumption that the speed of sound is If the speed of sound through the lesion here is
constant at 1540 m.s-1 is sometimes incorrect. slower than 1540 m.s-1, the echoes from behind the
lesion will take longer to return.
The image of the
If the sound along the tissues behind the
beam path varies, lesion will therefore
distances will be be placed on the
miscalculated and the screen too deep.
echoes placed in the
wrong position.
Module 10 Page 86
Brian Starkoff
Physical Principles of Ultrasound
Scan plane
orthogonal (90o)
plane
10
Module 10 Page 87
Brian Starkoff
Physical Principles of Ultrasound
• Harmonics
• Compound imaging imaging
depth
• Frame averaging
• Smoothing
Speckle
echo from deep
pulse 1 next pulse object is displayed
deep object is also echo from deep on the screen (at
returning an echo object now reaches the wrong depth)
transducer
Module 10 Page 88
Brian Starkoff
Physical Principles of Ultrasound
Module 10 Page 89
Brian Starkoff
Physical Principles of Ultrasound
Module 10 Page 90
Brian Starkoff
Physical Principles of Ultrasound
Doppler ultrasound
Physical Principles of Ultrasound Doppler effect
Brian Starkoff • The Doppler effect was first discovered
Module 11 by Christian Doppler in 1842.
at an angle.
(You should remember this formula)
The other individual components of the equation
have already been described.
• Colour
• Power
Therefore each blood cell is travelling slightly to and from
the different points of the transducer face. Each will now be described in more detail.
beam crossing
3 vessels
The sonographer can adjust the size of • When combined with a B-mode image,
the “gate” and its depth in the tissue. (as is normally the case) this range gate
can be set within the desired vessel.
Direction of Doppler beam and the
position of the sample volume.
pulsatile flow, continuous pulsatile flow which falls to continuous flow, although it may be
flow throughout systole zero or even reverses phasic (varies with respiration)
and diastole during diastole
References
Doppler Controls
Physical Principles of Ultrasound
The following Doppler controls will be discussed
Brian Starkoff
• Gain
Module 12 • Focus
Spectral
Topics: Doppler ultrasound • PRF
• Wall filter
• Doppler controls
• Doppler artifacts Colour • Motion differentiation
• Doppler quality control • Sensitivity
• Colour box size
Copyright © 2018, Brian Starkoff. Students and other persons studying ultrasound
are licensed to use this program and files for personal study purposes only.
• Colour-echo write priority
Copying (in whole or in part), use for any other purpose, or use by any other
person is prohibited without the prior, express permission of the author.
• Colour persistence and colour capture
6.1
Gain Focus
Excess gain will cause: Remember from module 2 that intensity = Power
area
therefore: beam area = intensity = echo strength
Spectral: - over measurement of velocities
- increased representation of spectral
broadening
PRF PRF
(pulse repetition frequency) (pulse repetition frequency)
also called ‘Velocity’ Range’ or ‘Scale’
• High PRF is required to accurately show fast
low prf high prf velocities without aliasing (an artifact which will
be described later)
but
high PRF will limit low velocity representation.
PRF Sensitivity
(pulse repetition frequency) 4 (also known as ‘packet size’ or ‘ensemble length’)
Sensitivity Sensitivity
The machine stores the signals from When the sensitivity is increased = more pulses are
1 each sample volume for each successive sent out for each line.
pulses 2 pulses
3 pulse in a set.
echoes
1
2
echoes 3 echoes
The set of echoes from each sample volume is used With more samples in each set, the machine is able to
to determine the average velocity in that volume. calculate smaller Doppler shifts (smaller velocities).
+ + +
chooses highest
_.
. 3
Persistence is often increased with Power Doppler to This control can be useful for producing a very well
improve colour filling of the vessel. colour filled image for recording purposes.
Aliasing Aliasing
(Also known as frequency aliasing)
Pulsed Doppler suffers from an inherent limitation Because of the pulsed nature of the beam, the
in the accurate detection of Doppler shifts (and machine can only obtain samples of the blood cell
therefore velocity calculations). movement.
Aliasing Aliasing
transmit transmit
Aliasing Aliasing
However if the sampling rate is too low for the frequency that
it is trying to measure, it does not have enough data to
Providing the points are close enough together, the correctly work out the frequency difference.
machine can construct the correct Doppler shift. Aliasing is now occurring
Aliasing Aliasing
Sampling rate
(PRF)
Doppler
shift
frequency This is what aliasing
appears like in a spectral
The sampling rate (the PRF) must be at least twice that Doppler waveform.
of the frequency it is trying to measure.
The Nyquist limit is the limit of the frequency that the
machine is able to correctly measure.
(It is ½ of the PRF). +PRF/2
e.g. if the PRF was 4000 Hz
then the machine could only In this case, the received Doppler shift is too high for the
0 Hz PRF and the trace extends beyond the top of the scale
represent 2000 Hz Doppler
shifts accurately (in both and is incorrectly produced at the bottom of the graph.
directions). -PRF/2
Aliasing Aliasing
Options to avoid or reduce aliasing: Options to avoid or reduce aliasing:
1. Move the baseline (This allows the machine to measure If the baseline is moved to the bottom (or top) of its limits, it
higher Doppler shifts (velocities) in one direction – but at is possible to measure frequency shifts up to the PRF (but
the expense of the reversed direction). only in one direction).
+1500 +2500
+1500 +3000
0 Hz Hz
0 0 Hz Hz
-1500 -500
Aliasing No aliasing
-1500 0
For example in this case, if the PRF was 3000 Hz and Aliasing No aliasing
aliasing was occurring, then moving the baseline lower
would allow higher Doppler shifts to be measured (in the
+ve direction).
Aliasing Aliasing
Options to avoid or reduce aliasing:
However there is a limit to increasing the PRF
2. Increase the PRF (on some machines this is shown as - The transducer must wait until echoes are back
‘velocity scale’ or ‘scale’) from the required depth before next pulse is sent.
Aliasing No aliasing
UNLESS
3. High PRF mode is used (if available)
12
High PRF mode Aliasing
Most machines will show the extra sample volume/s on the Other ways to avoid or reduce aliasing:
screen. In this case two sample volumes are shown meaning
that there are two pulses transmitting in the beam path. Reduce the Doppler shift frequency by:
Aliasing Aliasing
Other ways to avoid or reduce aliasing:
NOTE:
6. Reduce the imaging depth.
Aliasing does not occur with continuous wave
Less time would be required to wait for all echoes to (CW) Doppler because there is no sampling (the
be received from the set depth so the next pulse could
machine gets continuous feedback).
be sent out sooner. (i.e. the PRF could be increased).
That is why, despite the disadvantages of CW
Note that reducing the overall depth of the imaging field
Doppler, it is still an invaluable part of Doppler
of view will not automatically increase the Doppler PRF
(as would occur with the imaging PRF in B-mode ultrasound – particularly in cardiac applications
ultrasound), because the Doppler PRF is a separate where very high velocities may be encountered.
manual control.
CW Doppler is capable of correctly measuring
However reducing the depth would allow manual very high Doppler shifts (= high velocities).
adjustment to a slightly higher Doppler PRF if required.
strong strong
echo placed echo placed
strong reflector reflector strong reflector reflector
here here
• Generally, B-mode
(grey-scale) signal is
given priority on screen.
diastole systole
Harmonic Imaging
Contrast Harmonic Imaging
Harmonic imaging techniques can be used under two Harmonic imaging was developed for use with
different conditions: ultrasound contrast agents used in vascular studies in
which the microbubbles’ scattering and resonance
contained very high amplitude 2nd harmonic
- with the use of contrast agents frequencies (even higher than the fundamental
(contrast harmonic imaging) frequency).
f
(eg. 3 MHz 6 MHz ) (Another reminder to revise your notes on bandwidth in module 3).
I I
I I
f f f f
(eg. 3 MHz 6 MHz ) (eg. 3 MHz 6 MHz )
Question 42: Why are such short pulse lengths used in short pulse longer pulse
B-mode ultrasound?
Biological effects
Human studies: Biological effects
Large numbers of studies have been carried out on the Based on these findings, a curve can be plotted for
potential biological effects of ultrasound. critical values of intensity vs. time of insonation.
No reproducible studies have shown harmful effects by This curve is slightly different if a
diagnostic ultrasound. focussed beam is considered
100
An AIUM released statement5 in 1987 states in part: Possible effect
“In the low megahertz frequency range there have been 10 focussed beam
no independently confirmed significant biological effects in 1
mammalian
-2
tissues exposed to unfocussed ultrasound Intensity
-2
W cm 0.1
with intensities below 100 mW cm. Furthermore, for No effect
ultrasonic exposure times less than 500s and greater than Diagnostic pulse
1s, such effects have not been demonstrated even at .01 echo imaging
higher intensities, when the product of intensity and .001
lies well within
exposure time is less than 50 J cm-2 ” 2 3 4 5
the ‘no effect’
(SPTA intensities, frequency range 0.5 to 10 MHz)
1 10 10 10 10 10
Irradiation time (secs)
field.
Biological effects
Biological effects
But “It has been demonstrated in experiments with
A later statement (1992):
unperfused tissue that some Doppler diagnostic
equipment has the potential to produce biologically
“Known diagnostic ultrasound equipment as used significant temperature rises, specifically at bone/soft
today for simple B-mode imaging operates at tissue interfaces. The effect of elevated temperatures
acoustic outputs that are not capable of producing may be minimised by keeping the time for which the
harmful temperature rises. Its use is therefore not beam passes through any one point in tissue as short
contraindicated on thermal grounds. This includes as possible. Where output power can be controlled, the
endoscopic, transvaginal, and transcutaneous lowest available power level consistent with obtaining
applications.” the desired diagnostic information should be used.”
from The British Medical Ultrasound Society8 from The British Medical Ultrasound Society8
13
13 13
13
This may be performed on a simple domestic type VHS • Electronic focussing in the orthogonal (slice
video recorder, but is usually a more expensive thickness) plane
commercial type. It may even be a SVHS type – (Super
VHS). However the frozen image quality is inferior to
camera images. • Harmonic imaging – pulse inversion harmonics
Conventional 101101
uncoded pulse Coded pulse
Research has indicated that benign and malignant As the transducer records successive frames of the area,
tissues have different levels of compressibility. image recognition software matches and joins the frames
into one image.
This technique has shown significant promise in several
The process requires a smooth sweep of the transducer to
clinical areas of ultrasound including breast diagnosis.
produce an acceptable frame sequence.
3D ultrasound 3D ultrasound
3D ultrasound 3D ultrasound
Once an accurate volume data set is obtained, the With Section Reconstruction, the software can
3D data can be visualised in several different ways: reconstruct the data in any plane as set by the
sonographer.
• Section Reconstruction
• Surface rendering
• Volume Rendering
• Transparent rendering
3D ultrasound 3D ultrasound
The section reconstructions will still appear as 2D slices.
With Surface Rendering, voxels below a set value within
transverse sagittal a complete data set are removed.
www.firstimpression3d.com www.healthtap.com
Coronal reconstruction
of an IUCD This technique is particularly successful with obstetric
©GE Medical Systems Ultrasound
coronal
scans where the foetus is surrounded by amniotic fluid.
Transvaginal scan of a uterine fibroid
3D ultrasound 3D ultrasound
With Transparent Rendering,
the whole data set is used and It is critically important that the data sets are obtained
voxels with a maximum (or as accurately as possible. Each scan plane image in
minimum) value are displayed, the set should be a fixed and a known distance from
and others are excluded. the previous image.
3D ultrasound 3D ultrasound
External tracking: Freehand acquisition:
The transducer is either mechanically attached to an The transducer is swept through an area (either linearly or
articulated arm or tracked by remote magnetic sensors. in an arc). The machine captures successive frames at a
set rate.
3D ultrasound 3D ultrasound
Automated acquisition: Automated acquisition: - Mechanical probe
The probe has an inbuilt motor which arcs the curved
The transducer is designed to automatically change the array through the orthogonal plane.
scan plane in an arc. Because the movement is
automated, a very accurate data set can be obtained.
3D ultrasound 4D ultrasound
Automated acquisition: - Matrix probe 4D ultrasound is real time 3D ultrasound.
The probes steer the scan plane electronically. The head
consists of many thousands of individual elements. Conventional 3D ultrasound produces one Volume Data
Set at a time. This is then reconstructed as required.
The rapid acquisition of data sets in the automated probes
mean several data sets per second can be obtained. With
sufficient computer processing power, reconstructions can
be done dynamically so that the 3D images are produced
with acceptable frame rates.
These probes are much more compact the mechanical Frame rates with the matrix transducers are superior to
ones and produce faster data sets. the mechanical ones which make them preferred for
cardiac applications.
battery power which means they can be used: 3. Hedrick R, Hykes D. Starchman D: Ultrasound Physics and Instrumentation 3rd
ed. Mosby 1995
• At accident sites 4. Gill, R: The Physics and Technology of Diagnostic Ultrasound:
• On sports fields A Practitioner’s Guide. High Frequency Publishing, Sydney,
Australia 2012
• In the field for defence force applications 5. Americian Institute of Ultrasound in Medicine: Bioeffects considerations
for the safety of diagnostic ultrasound, J Ultrasound Med 7:S1, 1988.
= 1.5 mm
Question 12:
Question 13:
1011010
(a) Increase the Power output. It is one of the controls
on the ultrasound machine.
26 24 23 21
(b) Decrease the area of the beam by moving the
= 64 + 16 + 8 + 2 = 90 focus to the area of interest. Focus placement is
another one of the controls on the machine.
(As we will see later, decreasing beam area also
(Note that the “0’s” have been omitted for simplicity) improves lateral resolution).
R= = 0.0064
= 10 log (0.001
1
) beam
Z2 + Z1
=
1.62 + 1.38
= 10 log 0.001 The decibel loss that occurs at this point of reflection is now
calculated.
= 10 x -3
= -30 Transmitted dB = 10 log ( II ) o
= 10 log 0.0064 = 21.9 dB loss
beam
therefore a 30 dB loss occurs Therefore total loss = 40 + 21.9 dB
= 61.9 dB
R1 =
1
= 0.39 T = 0.61 -3
Z2 + Z1 30 + 6.93 = 169.4 x 10 m
-3 = 154 x 10 m
( )=( )
Z2 - Z 1
2
6.93 - 1.6 2
R =
2 = 0.39 T = 0.61 = 0.1694 m = 0.154 m
Z2 + Z1 6.93 + 1.6
= 16.94 cm = 15.4 cm
Ttotal = 0.61 x 0.61 = 0.37 = 37%
This is a big improvement from not having a matching layer.
-1 -1
1.5 x 1.5 x 10 = 0.4172 x 10
= m
2.052
-1
= 0.04172
= 1.096 x 10 m
o
0 = 2.391
= 10.96 cm
d
2 I -10dB
will be wider than the
Near field length is calculated by the formula = ( 1
max I)
4 3 dB beam width. 2
f = 1
= number of lines x time for each line T
= 1
26 x 10 -3 Hz
= 200 x 0.13 ms
1 3
= x 10 Hz
= 26 ms 26
3
= 0.03846 x 10 Hz
= 38.46 Hz
Question 35(a): 1 1 1 1
Question 36:
2 3 2 2 2 1 20
= 8 + 4 + 2 + 1 = 15 dB = 20 log ( AA )
o
(+ 1 for the case where there is 0 0 0 0)
= 16 different values = 20 log ( 1000
10
)
Question 35(b): 1 1 1 1 1 1 1 1 = 20 x 2
27 26 25 24 23 22 21 20 = 40 dB
= 128+64+32+16+8+4+2+1 = 255
Note that because we are considering voltage changes, the
(+ 1 for the case where there is 0 0 0 0) V I
20 log ( V ) formula is used - not the 10 log ( I ) intensity
= 256 different values o o
change formula.
A Index B
Artifacts (B-mode) Artifacts (Doppler)
Page Page Page Page
15 Absorption 81 Anisotropy 104 26 Bandwidth
Aliasing
84 Beam width 108 Anechoic space
18 Acoustic impedance artifact 74 B-colour
83 Comet tail
33 Acoustic lens 80 Edge artifact 96 Intrinsic spectral 30 Beam profile
broadening
79 Enhancement Beam steering (electronic steering)
58 Acoustic lens 108 Pulse-echo mirror 54
89 Equipment related
- linear array 107 Spectral mirror 31 Beam width
86 Lens (or lens effect)
23 Acoustic lens 109 Temporal resolution
89 Main bang 84 Beam width artifact
- simple transducer 86 Mirror
109 Twinkle artifact
89 Near field 8 Binary numbers
53 Acoustic windows
88 Range ambiguity 79 Assumptions of 115 Biological effects
104 Aliasing 86 Refraction ultrasound
81 Reverberation 115 Biological effects - thermal
38 A-mode ultrasound 15 Attenuation
83 Ring down 117 Biological effects - mechanical
64 Analog-digital conversion 80 Shadowing 45 Axial resolution
84 Side lobe 60 B-mode steering
1 Anechoic 75 Axial resolution
85 Slice thickness 39 B-mode ultrasound
- measurement
108 Anechoic space artifact 87 Speckle
81 Anisotropy 86 Speed of sound
89 Technique related
C D Page
22 Damping material Page
Page Page 89 Dead zone 100 Doppler controls
76 Calliper calibration 93 Continuous wave Doppler 11 Decibels 92 Doppler equation
117 Cavitation 111 Contrast agents
69 Demodulation 97 Doppler measurements
74 Colour B-mode 112 Contrast Harmonic Imaging
67 Cineloop 24 Destructive interference 91 Doppler ultrasound
50 Contrast resolution Duty factor
102 Colour box (Doppler) 16 Diffraction 25
77 Contrast resolution
103 Colour capture (Doppler) 99 Directional Power Doppler 37 Dynamic aperture
- testing
98 Colour Doppler 24 Constructive interference 16 Divergence 13, 68 Dynamic range
103 Doppler artifacts 36 Dynamic receive focus
102 Colour-echo write priority (Doppler) 59 Convex transducer
104 Aliasing
52 Colour resolution 59 Curved array transducer 108 Anechoic space artifact
96 Intrinsic spectral
83 Comet tail artifact broadening
24 Complex interference 108 Pulse-echo mirror
107 Spectral mirror
40 Compound imaging 109 Temporal resolution
109 Twinkle artifact
99 Doppler Tissue Imaging (DTI)
Page
E 102
1
Echo write priority (Doppler)
Echogenic
F H I
Page Page
1 Echogenicity 109 Flow phantom (Doppler)
Page
66 Image memory
2 Echotexture 111 Harmonics
33 Focussing 26 Intensity variation - spatial
80 Edge artifact 114 Harmonics – Pulse inversion
124 4D ultrasound 27 Intensity variation – temporal
70 Edge enhancement 106 High PRF mode
70 Frame averaging 70
111 Interpolation
1 Hypoechoic
121 Elastography Intravascular contrast agents
42 Frame rate – B-mode
121 Elastography - strain 96 Intrinsic spectral broadening
103 Frame rate – Colour Doppler
121 Elastography – shear wave
104 Frequency aliasing
34 Electronic focussing
L 119
48
Laser camera
Lateral resolution
Electronic sector transducers
G
54
75 Lateral resolution - measurement
54 Electronic steering Page
33 Lens
120 Encoded pulses 32 Grating lobes
58 Lens - linear array
79 Enhancement 73 Grey scale mapping 23 Lens – simple transducer
101 Ensemble length (Doppler) 102 Grey scale priority 86 Lens artifact (or lens effect artifact)
89 Equipment related artifacts 51 Grey scale resolution 40 Line density
122 Extended field of view ultrasound 57 Linear array transducer
M P
Page Page Page Page
89 Main bang artifact 101 Packet size (Doppler) 68 Pre processing
117 Microstreaming 70 Edge enhancement
23 Matching layer 86 Mirror artifact (B-mode) 122 Panoramic ultrasound
70 Frame averaging (Persistence)
66 Matrix resolution 107, 108 Mirror artifacts (Doppler) 70 Persistence (B-mode) 70 Interpolation
59 Matrix transducers (linear) 103 Persistence (Doppler) 70 Persistence (Frame averaging)
41 M-mode
56 Matrix transducers (sector) 54 Phased array transducer 71 Smoothing
119 Multi-imaging camera
71 Reject
74 Measurements 21 Piezoelectric element - construction
37 Multiple beam formers 71 Write zoom
117 Mechanical index 22 Piezoelectric element - operation
24 Multiple element transducers 102 Priority
66 Pixel resolution
118 Mechanical index safety limits 35 Multiple focal zones 5 Propagation of sound
72 Post processing
66 Memory 25 Pulse duration
73 Grey scale mapping
72 Read zoom 25 Pulse-echo imaging
Q S
Page
Page
74 Quality control (B-mode)
109 Quality control (Doppler)
75 Axial resolution
109 Flow phantom Page Page Page
76 Calliper calibration 65 Scan converters 2 Sonologist
109 String phantom 96 Spectral waveform
77 Contrast resolution
16 Scattering Sound-tissue interactions 86 Speed of sound
75 Dead zone
101 Sensitivity (Doppler) 15 Absorption artifact
75 Lateral resolution
121 Shear wave elastography 15 Attenuation 109 String phantom
75 Registration
16 Diffraction
77 Slice thickness 80 Shadowing 1 Study program
16 Divergence
Page Page 31 Side lobes
17 Reflection
Radial transducers 18 Reflection coefficient 84 Side lobe artifact
R
60 14 Refraction
88 Range ambiguity artifact 14 Refraction 68 Signal compression 16 Scattering
95 Range gating 86 Refraction artifact 62, 68 Signal processing 26 Spatial Intensity variation
72 Read zoom 71 Reject 85 Slice thickness artifact
45 Resolution 25 Spatial pulse length
54 Real-time transducers 77 Slice thickness
45 Axial 45 Spatial resolution
59 Curved array - measurement
52 Colour 60 Specialised transducers
54 Electronic sector 71 Smoothing
50 Contrast
57 Linear array 87 Speckle artifact
51 Greyscale 2 Sonographer
60 Radial 48 Lateral 96 Spectral analysis
60 Specialised transducers 50 Temporal 96 Spectral bandwidth
119 Recording methods 81 Reverberation artifact 107 Spectral mirror artifact
17 Reflection 83 Ring down artifact
T Page