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subjective experience of clouding of consciousness, or what she also
called "mental fog", after taking a single dose of the antihistamine
chlorpheniramine for her cottonwood allergy while on a cross-country
road trip. She described feeling "out of it" and being in a "dreamy
state". She described a sense of not trusting her own judgment and a
dulled awareness, not knowing how long time went by.
Clouding of consciousness is not the same thing as depersonalization
even though people affected by both compare their experience to that
of a dream. Psychometric tests produce little evidence of a
relationship between clouding of consciousness and
depersonalization.
In Diseases
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Patients recovering from COVID-19 report experiencing 'brain fog',
which can reflect a wide variety of neurological and psychological
symptoms linked to COVID-19.
Many people with fibromyalgia experience cognitive
problems (known as "fibrofog" or "brainfog"), which may involved
impaired concentration, problems with short- and long-term memory,
short-term memory consolidation, working memory, impaired speed
of performance, inability to multi-task, cognitive overload, and
diminished attention span. About 75% of fibromyalgia patients report
significant problems with concentration, memory, and multitasking.
A 2018 meta-analysis found that the largest differences between
fibromyalgia patients and healthy subjects were for inhibitory control,
memory, and processing speed. Many of these are also common
symptoms of ADHD (attention deficit hyperactivity disorder), and the
two conditions have been linked via studies, to the point that a
diagnosis of fibromyalgia has been proposed as an indication to also
screen for ADHD. In particular, the "brain fog" of ADHD has been
linked to "fibro fog". It is alternatively hypothesized that the increased
pain compromises attention systems, resulting in cognitive problems.
In chronic fatigue syndrome, also known as myalgic
encephalomyelitis, the CDC's recommended criteria for
diagnosis[39] include that one of the following symptoms must be
present:[39]
Problems with thinking and memory (cognitive dysfunction,
sometimes described as "brain fog")
While standing or sitting upright; lightheadedness, dizziness,
weakness, fainting or vision changes may occur (orthostatic
intolerance)
Lyme disease's neurologic syndrome, called Lyme encephalopathy, is
associated with subtle memory and cognitive difficulties, among other
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issues.[40] Lyme can cause a chronic encephalomyelitis that
resembles multiple sclerosis. It may be progressive and can involve
cognitive impairment, brain fog, migraines, balance issues, and
extensive other issues.[citation needed]