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BD Life Sciences

Specimen Management
Product catalogue
About BD
BD is one of the largest global medical technology companies in the world and is advancing the world of health by
improving medical discovery, diagnostics and the delivery of care. The company supports the heroes on the frontlines
of healthcare by developing innovative technology, services and solutions that help advance both clinical therapy for
patients and clinical process for healthcare providers. BD and its 65,000 employees have a passion and commitment
to help enhance the safety and efficiency of clinicians’ care delivery process, enable laboratory scientists to accurately
detect disease and advance researchers’ capabilities to develop the next generation of diagnostics and therapeutics.
BD has a presence in virtually every country and partners with organisations around the world to address some of
the most challenging global health issues. By working in close collaboration with customers, BD can help enhance
outcomes, lower costs, increase efficiencies, improve safety and expand access to healthcare. In 2017, BD welcomed C.
R. Bard and its products into the BD family. For more information on BD, please visit bd.com.

More than
40B + Serving
70,000 devices made 190+
associates annually countries

2
Table of contents
About BD 2

The history of BD Vacutainer® systems 4

Portfolio overview 6
BD specimen collection portfolio 6
BD Laboratory Consulting ServicesTM 7
Tube dimensions and sample volumes 8
Labelling and packaging information 9

Patient safety 10
Sample management and analysis 10
Impacting outcomes 11

Sustainability 12

Venous blood sampling 13


Order of draw 13
Coagulation analysis 16
Serum analysis 19
Plasma analysis 20
Haematology 24
Glucose analysis 25
Speciality tubes 26
ESR 27

Cell and biomarker preservation 28

Blood collection 35
Push button safety blood collection sets 35
Safety blood collection needles 39
Blood collection needles 42
Accessories, adapters and holders 43
Stretch tourniquets 44

Capillary blood sampling 45

Arterial blood sampling 49

Urine collection products 51

Additional information and product quality statement 54

3
The history of BD Vacutainer ®

systems
1947 1950 1952 1964
Joseph Kleiner invents First disposable First BD micro lancet is First BD
Evacutainer, the start of blood collection set launched (BD Unopette™ Vacutainer®
the BD Vacutainer® blood was developed for Products) Heparin
collection system journey the Red Cross glass tube is
launched

1949 1950 1960


The Evacutainer First glass EDTA, BD opens
is patented Serum & Oxalate Broken Bow, NE
Vacutainer® tubes manufacturing
are launched plant

2002* 2000 1997


BD Vacutainer® Urine BD Vacutainer® BD Vacutainer®
Preservative Tube for Stretch latex-free PPTTM tube is
urinalysis is launched tourniquet is launched launched

2000* 1999 1993


BD Vacutainer® BD Vacutainer® Eclipse™ BD Microtainer®
2003* Citrate plastic
tube is launched
needle is launched with
safety shield
Quikheel™ lancet
is launched
BD Vacutainer® Blood
Transfer Device and
BD Vacutainer® Luer-
Lok™ Access Device
(LLAD) are launched

2003 2006 2010


BD Vacutainer® Push BD Microtainer™ BD Microtainer®
2003* Button blood collection
set is launched
Contact Activated
Lancets are launched
MAP EDTA tube
is launched
BD Vacutainer®
Eclipse™ blood
collection
needle with pre-

2005
attached holder
is launched
BDTM P100 tube and
2009
BD Vacutainer®
PAXgene® Blood P800 tubes are
RNA tube are launched launched
Learn more at:

bd.com/
70YrsHealthy 70 years of better outcomes for
patients and professionals.
4
The history of

A story of innovation
BD Vacutainer®
systems

The BD Vacutainer® family of solutions focuses on delivering diagnostic accuracy, a safe


environment for patient and healthcare professionals, reduced patient pain, specimen
integrity and quality and total cost of ownership.
1970 1975 1979
BD opens Sumter, SC BD launches BD BD Life Sciences-
manufacturing plant Vacutainer® SST™ Preanalytical Systems
Glass Tube (serum becomes its own
separation tube) division, called
“Vacutainer Systems”

1968 1971 1977


BD launches BD launches BD Microtainer®
BD Vacutainer® BD Vacutainer® Urine Tubes are launched
Multiple Sample Collection Tubes for small sampling 1980
Straight Needles for culture First BD Vacutainer®
Citrate glass tube
is launched

1993 1990 1988 1982


BD Vacutainer® BD Vacutainer® plastic tubes BD launches
BD opens
CPT™ tube is are launched and most tubes Hemogard™
Plymouth, UK
launched are transitioned to plastic closure
manufacturing
plant

1992* 1988
BD Microtainer® BD Vacutainer®
Safety Flow™ Safety-Lok ™ blood
lancet is launched collection set is launched

2013 2016 2018


BD Sentry™ Safety BD Vacutainer® PAXgene® Blood
Lancet is launched Barricor™ blood ccfDNA tube
collection tube is is launched
launched

2012 2016 2016 2019


BD Vacutainer® EclipseTM Optimised design – BD Vacutainer® BD Vacutainer®
Signal™ blood collection BD Vacutainer® EclipseTM UltraTouch™ Push Button brand celebrates
needle is launched SignalTM blood collection blood collection set 70th birthday
needle is launched is launched

Thank you for trusting the BD Vacutainer® brand to enable


accurate diagnostics that shape the course of care.
* Approx. date shown. Varies by region WW
5
Portfolio overview
BD specimen collection portfolio
The BD portfolio ensures safer care during the preanalytical phase

BD Vacutainer® Venous BD Vacutainer® BD Arterial Blood BD Microtainer® BD Innovative


Blood Collection Closed Urine Collection System: Capillary Collection Solutions:
System: Collection System: Provide clinically superior System: Specifically designed
Full range of tubes Reduces mixed growth and safe solutions to A complete solution to meet emerging clinical
and venous access and contaminated standardise collection designed and developed and diagnostic needs.
devices to meet any samples saving costs, of arterial samples for your most fragile
laboratory and patient time and diagnostic dedicated to Critical Care patients.
population needs. and treatment delays. Panel testing.

BD Vacutainer® Evacuated Blood Collection System


The BD Vacutainer® evacuated blood collection system is
the most widely-used blood stabilisation tube in the world.

BD Vacutainer® EclipseTM blood


BD Vacutainer ® collection needle - a safety needle
Holder for venous blood sampling

Sterile evacuated
BD Vacutainer® SSTTM II
Advance tube

Safety valve for


multiple sampling

• CE marked to ensure product quality


• Reproducible blood draw with each tube having a predetermined vacuum
BD Vacutainer® Push Button blood
• Comprehensive range of additives to stabilise most blood components collection set - a safety needle with
in-vein activation
• BD HemogardTM safety closure provides optimal protection for users from
blood exposure
• Sterile tube and needle ensure no microbiological contamination of
samples
• A range of labels to ensure traceability of collected patient samples

6
Portfolio

Portfolio overview
overview

BD laboratory consulting servicesTM – helping deliver


better clinical outcomes

Accreditation
support

Product
evaluation

Troubleshooting

Best practice training

PAQC/Assessment

Accreditation support Troubleshooting Preanalytical Quality Check


• Optimised accreditation support • On-site support (PAQC) / Assessment

• Real-time support • Technical issue resolution •E


 xpert preanalytical process
examination
• Customisable • Systematic approaches
•D
 evice storage, sample collection
and analysis
Product evaluation Best practice training •U
 nderstand impact of processes
• BD white papers • Healthcare worker safety on quality
• On-site product evaluation support • Critical care collection • Blood
• Change management planning • Venous blood collection • Urine
and support
• Capillary collection •A
 rterial blood gases
• Blood culture specimen collection •S
 pecimen transport
• Plasma vs Serum
• Others: blood basics and basic
anatomy

7
Portfolio overview
Tube dimensions and sample volumes
Tube dimensions and sample volumes
BD Vacutainer® tubes are available in three different sizes as pictured below, each with different sample volumes. Tubes for special
analysis may have a different size (e.g., sedimentation tubes).
The volume given in mL on the tube refers to the amount of blood that will be taken from the patient. For tubes with a fluid
additive, the final volume may deviate from this (i.e., amount of blood + additive).

13mm x 75mm 13 mm x 100 mm 16 mm x 100 mm


Original size

Original size

1.8mL 3.5 mL Original size 6.0 mL


2.0mL 4.0 mL 8.0 mL
2.5mL 4.5 mL 8.5 mL
2.7mL 5.0 mL 9.5 mL
3.0mL 5.5 mL 10.0 mL
3.5mL 6.0 mL 11.0 mL
4.0mL 7.0 mL
4.5mL
5.0mL

8
Portfolio

Portfolio overview
overview

Labelling and packaging information


Tube labelling
1 2 1 Fill volume
1
2 Fill marking
4 3 BD catalogue number
3 4 BD Vacutainer® notch label - colour coding
and attachment point for secondary label
5 Type of tube and additive concentration
(if applicable)
8 7 6 5 6 Sterilisation symbol
7 Expiry date
8 Batch number

Paper label Block label See through label Transparent label


The standard label providing a A formatted paper label with Product specification are sprayed directly In the same format as a
free text space for writing patient defined areas for writing specific onto the tube with no provision for hand paper label but with the
ID & sample information. patient ID & sample information written information. additional benefit of being
see through to allow greater
visibility of sample.

Box 1 2
1 Type of tube & additive
concentration (if applicable)
2 Pictorial instruction for use
4 6
3 3 BD catalogue reference number
4 Shelf pack quantity
5 5 Product expiration date & lot number
6 Relevant symbols
7 Country of origin
8 7 8 Draw volume and tube size

Case
1 Type of tube and additive
concentration (if applicable)
2 BD catalogue reference number
1 3 Case quantity
4 Relevant symbols
2 5 Country of origin
6 Draw volume and tube size
4
3

6 5

9
Patient safety
Sample management and analysis
Driving safe and accurate sample management and analysis
throughout the patient journey

Did you know the majority of laboratory errors


occur during the preanalytical phase?1
About 2/3
"The most commonly performed of laboratory
errors occur during
invasive medical procedure is wreaking the preanalytical

havoc on how patients are being phase 2

diagnosed, medicated and managed."


Dennis J. Ernst, Director of the Center for Phlebotomy Education
95%
of diagnostic
Up to 70% of clinical decisions are based on laboratory data.1
delays are the result
Because of this, laboratory errors have a major
of blood collection
impact on the diagnostic and treatment pathways. errors 3

The preanalytical phase, step by step


Preanalytical errors can occur at any step during the process

Storage Collection Transportation Sample prep Sample quality Analysis

Examples of preanalytical errors

Expired tube Patient ID Temperature out Incorrect label Haemolysed sample Incorrect
centrifuge
not confirmed of range

Sample Temperature Syringe collection Non-standard time Insufficient sample Lipaemia


> 25°C volume

10
Patient

Patient safety
Safety

Impacting outcomes
Poor sample quality contributes to errors2 that may:
> cause unnecessary patient suffering4
> impact clinical outcomes6
> effect compliance to regulatory standards

3-12 % 3.3 days


of hospital laboratory Patients spend an extra
errors lead to adverse 3.3 days at the hospital
events 4 after a contaminated
blood culture 5

BD can support your efforts for patient safety by maximising, improving and
standardising sample management and analysis
Improve difficult Improved
vein access traceability

Improved
Shorter fill
Optimising sample stability
time Maximising and
clinician standardising
performance workflows,
Greater
and processes and
treatment Faster lab
efficiency procedures
accuracy response time

Improving
diagnostic Prevent
Reduce patient accuracy needlestick injuries
pain

Better reliability Better sample quality

Less bacterial overgrowth

1. Bonini P, Plebani M, Ceriotti F, Rubboli F. Errors in laboratory medicine. Clin Chem. 2002;48(5):691–8
2. Plebani M & Carraro P. Mistakes in a stat laboratory: types and frequency. Clin Chem. 1997;43(8):1348–135.
3. Zwang O Albert R. Analysis of strategies to improve cost effectiveness of blood cultures. J Hosp Med. 2006;1(5):272–6.
4. College of American Pathologists, Valenstein P, Raab S, Walsh M. Identification errors involving clinical laboratories: a College of American Pathologists Q-Probes study of patient and specimen identification
errors at 120 institutions. Arch Pathol Lab Med. 2006;130(8):1106–13.
5. Bush RA, Mueller T, Sumwalt B, Cox SA, Hilfiker ML. Assessing pediatric trauma specimen integrity. Clin Lab Sci. 2010;23(4):219–22.
6. Green S. Tracking the cost of poor quality and errors in preanalytical processes. Poster presented at: 63rd American Association of Clinical Chemistry Annual Conference; September, 2011; Atlanta, Georgia, USA.

11
Sustainability
Focus on creating shared value
Through the BD 2020 sustainability goals, we actively contribute to local and global efforts to address challenges facing
the healthcare industry, society at large and the planet. These goals are divided into four key areas: innovation, access,
efficiency and empowerment.

Healthcare safety, outcomes Healthcare in resource-limited


and cost populations
• Innovate key healthcare processes such as • Develop low-cost innovations to address
medication management and lab automation leading causes of mortality and morbidity
• Develop innovations and informatics to • Collaborate on health system
enable disease management across the care strengthening with leading agencies and
continuum nongovernmental organisations
• Enable the transition from research into clinical • Further expand BD manufacturing, product
practice array and employment in emerging
countries
• Provide solutions that improve healthcare
worker and patient safety

Environmentally sound products Positive workforce and


and resilient operations community
• Reduce greenhouse gas emissions • Increase the diversity of our workforce,
particularly in leadership roles
• Eliminate priority materials of concern
• Achieve best-in-class associate safety
• Minimise environmental footprint in
performance
manufacturing
• Drive social impact and associate
• Drive supplier responsibility evaluation
engagement through volunteer programs
methodology
• Partner with nonprofits
• Improve life cycle impacts of products

Find out more about our sustainability goals:


bd.com/en-us/company/sustainability-at-bd

12
Venous
blood

Venous blood sampling sampling

Order of draw
Recommendations CLSI (NCCLS), Vol. 23, No. 32, 8.10.2

With a Wingset: With a Wingset: Recommended


With a Needle:
With Blood Culture Without Blood Culture inversions

Blood Culture Bottles


Discard tube N/A
(aerobic, anaerobic)

3-4

5-6

8-10

8-10

8-10

Others Others Others


(ACD, VS, Aprotinine (ACD, VS, Aprotinine (ACD, VS, Aprotinine 8-10
and Thrombine) and Thrombine) and Thrombine)

13
Venous blood sampling
Coagulation analysis

Sodium citrate
BD Vacutainer®
Trisodium citrate is used as an anticoagulant for coagulation Plastic Citrate Tube
investigations. It works as an anticoagulant by forming draw volume guide
complexes with metal ions such as calcium, thereby inhibiting
Maximum fill*
the coagulation cascade. Anticoagulation with trisodium
citrate is reversible. Minimum fill
indicator
BD Vacutainer® Citrate Tubes contain buffered trisodium
citrate in accordance with recommendations:
• 0.105 M or 0.109 M of buffered trisodium citrate solution,
equivalent to 3.2% trisodium citrate 1.8 mL 2.7 mL
draw draw
*According to CLSI tube tube
• 0.129 M of buffered trisodium citrate solution, equivalent to Guideline, Dec 2010, 13 mm x 75 mm 13 mm x 75mm
Doc. GP39-A6 (replaces full draw full draw
3.8% trisodium citrate H01-A6)

The blood to additive ratio is 9:1.


BD Vacutainer® plastic (PET/PP) Citrate Tubes
BD Vacutainer® Citrate Tubes are also suitable for carrying
out special test procedures such as the platelet function The plastic citrate tubes made from polyethylene
assay PFA-100®*. terephthalate (PET) and polypropylene (PP) feature innovative
tube geometry that minimises tube headspace and
Fill line marking associated platelet activation to optimise activated partial
thromboplastin time (APTT) monitoring of unfractionated
The significance of the correct ratio of blood to additive
heparin patients.
for coagulation samples is well documented. The correct fill
amount is critical for correct coagulation analysis. All BD Vacutainer® Citrate Tubes combine the following
BD Vacutainer® plastic coagulation tubes have a mark advantages:
indicating the minimum fill level.
• Clinically equivalent performance to the recognised global
Glass tubes “Gold Standard”: the 4.5 mL BD Vacutainer® glass buffered
citrate tube1,2.
All BD Vacutainer® glass coagulation tubes have specialised
internal silicone coating to minimise contact activation. • Clinically proven in multi-centre
clinical trials for coagulation Clinically
testing across all major patient equivalent
populations. performance to
the recognised
• Evaluated with the most
widely used coagulation Gold
analytical systems. standard

* PFA-100 is a registered trade mark of Siemens.


1. BD Ref. VS5936: Evaluation of BD Vacutainer® Plus 2.7 and 1.8mL Sodium Citrate Coagulation Tubes Using The ELECTRA 1400cTM Analyser. BD, Franklin Lakes, NJ, USA November 2001
2. BD Ref. VS5966: Evaluation of 0.109M BD Vacutainer® Plus Plastic and 0.105M BD Vacutainer® Glass Sodium Citrate Tubes for PT and APTT Using the Sysmex CA - 1500 Analyzer. BD, Franklin Lakes, NJ, USA June 2002

14
Venous
blood

Venous blood sampling sampling

Coagulation analysis
Centrifugation conditions
• 1,500 g for 15 minutes at 18-25°C**

**Unless otherwise specified on product labeling. Citrate tubes should


be centrifuged at a speed and time to consistently produce platelet
poor plasma (platelet count <10,000/µL) per CLSI Guidelines.

BD Vacutainer® Citrate Tubes


Alternate Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
Cat. no. (mL)

363080 363047 1.8 13 x 75 Trisodium citrate (0.109 M, 3.2%) None PET/PP Paper BD HemogardTM

363083 363048 2.7 13 x 75 Trisodium citrate (0.109 M, 3.2%) None PET/PP Paper BD HemogardTM

All tubes are supplied in boxes of 100 / cases of 1,000

15
Venous blood sampling
Serum analysis

Serum tubes
Serum tubes are available in plastic (PET) variants. In glass
tubes, the surface acts as a clot activator. In plastic tubes,
silica particles are added as the clot activator. These tubes are
labelled with the acronym CAT (clot activator tube).

Clotting times
The recommended minimum clotting time for the serum
tubes is 60 minutes.

Centrifugation conditions
≤ 1,300 g for 10 minutes at 18-25°C

Further information
Clinical and technical information is available on request.

BD Vacutainer® Serum Tubes

Alternate Draw volume


Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
Cat. no. (mL)

367812 369032 4.0 13 x 75 Silica (clot activator) None PET Paper BD HemogardTM

367815 6.0 13 x 100 Silica (clot activator) None PET Paper BD HemogardTM

367820 10.0 16 x 100 Silica (clot activator) None PET Paper BD HemogardTM

All tubes are supplied in boxes of 100 / cases of 1,000

16
*Partial-draw tube
Venous
blood

Venous blood sampling sampling

Serum analysis
BD Vacutainer® SSTTM II Advance Tubes
These tubes contain an inert gel barrier that separates the
serum from the blood clot during centrifugation, preventing
contamination of the serum. For example, in serum certain
analytes such as potassium, phosphorus and glucose should
be separated from the cells within a few hours - otherwise
the results will be significantly impacted. Using BD SSTTM II
Advance tubes, routine analytes in clinical chemistry such as
potassium are still stable after a week of storage at 2-8ºC.
Clinical evaluation of special chemistries such as therapeutic
drugs, proteins, peptides, steroids and vitamins demonstrates
a high degree of stability within the BD SSTTM II Advance1,2,3.
The main advantages of gel tubes versus non-gel tubes are:
• Stable barrier between serum and clotted blood during
transportation and storage, leading to better analyte
Centrifugation conditions
stability.
1,300-2,000 g for 10 minutes
• Better sample quality.
• Workflow optimisation: short centrifugation time, sample Storage conditions
processing and archiving in the primary tube.
BD Vacutainer® SSTTM II Advance should be stored at 4-25°C
• No requirement for secondary tubes, reducing the possibility and protected from direct sunlight during storage. Cooling of
of misidentification:. the tube by or during centrifugation can affect the movement
capability of the gel. The optimum separation of serum and
Clotting times coagulated blood is achieved at a temperature of 20-25°C.
The minimum recommended clotting time for
BD Vacutainer® SSTTM II Advance tubes is 30 minutes. Further information
Clinical and technical information is available on request.

BD Vacutainer® SSTTM II Advance Tubes


Draw volume
Cat. no. Size (mm) Additives Separator Material Label Cap closure Cap colour
(mL)

367956 3.5 13 x 75 Silica (clot activator) Gel PET Paper BD HemogardTM

367954 5.0 13 x 100 Silica (clot activator) Gel PET Paper BD HemogardTM

367958 8.5 16 x 100 Silica (clot activator) Gel PET Paper BD HemogardTM

All tubes are supplied in boxes of 100 / cases of 1,000


* Partial-draw tube
1. BD White Paper VS7050: Therapeutic Drug Compatibility in BD Vacutainer® SSTTM II Plus Tubes, 2004.
2. BD White Paper VS7051: Performance of BD Vacutainer® SSTTM II Plus Tubes for Special Chemistry Testing, 2004.
3. BD White Paper VS5778: Comparison of BD Vacutainer® SSTTM Plus Tubes with SSTTM II Plus Tubes for Common Analytes, 2001.
4. BD White Paper VS7228: Performance of BD Vacutainer® SST II Advance tubes at Four and Five Minute Centrifugation Times, 2004.

17
Venous blood sampling
Serum analysis
BD Vacutainer® Rapid Serum Tube (RST)
This tube combines the advantages of a thrombin-based
clot activator with a gel barrier, enabling rapid results and
extended stability.
The main advantages of BD Vacutainer® Rapid Serum Tubes
versus other tubes:
• High-quality serum production.1.
• Five-minute centrifugation time after the blood sample is
taken.
• Stable barrier between serum and clotted blood during
transportation and storage, therefore better analyte
stability.
• Workflow optimisation: short centrifugation time, sample Centrifugation conditions
processing and archiving in the primary tube. 4,000 g for 3 minutes at 23-27ºC or
• No requirement for secondary tubes, reducing the possibility 2,000 g for 4 minutes at 23-27ºC or
of misidentification. 1,500-2,000 g for 10 minutes at 23-27ºC

Clotting times Further information


The minimum recommended clotting time for BD Vacutainer ®
Clinical and technical information is available on request.
Rapid Serum Tubes is 5 minutes.

BD Vacutainer® Rapid Serum Tubes

Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

Thrombin-based medical
368774 5.0 13 x 100 Gel PET Paper BD HemogardTM
clotting agent

All tubes are supplied in boxes of 100 / cases of 1,000

1. BD White Paper VS8133: Evaluation of Serum Quality in BD Vacutainer® Rapid Serum Tubes with BD HemogardTM Closure, 2010

18
Venous

Venous blood sampling blood


sampling

Serum Plasma
Turnaround time1-2 Turnaround time1-2
Before centrifugation, serum samples The anticoagulation action of
require between 5 to 60 minutes to heparin allows for immediate
coagulate and several factors affect centrifugation of the specimen.
the process.

Sample quality3-8 Sample quality3-8


• Serum is an acellular sample • Plasma contains residual cells
• Coagulation processes increase the • Analytical variance is reduced
analytical variance • Potassium values are reliable
• Pseudohyperkalaemia is observed • Analyte stability is generally
• Long-term stability is high for the shorter than in serum samples
majority of analytes

Fibrin Formation9 Fibrin formation9


Inadequate clotting may result in Heparin prevents the coagulation
fibrin formation during and after process from effectively removing
centrifugation, as well as interfering the cause of fibrin formation. Cold
Slow Fast
with some tests. storage can activate coagulation.

Sample yield10 Sample yield10


~45% ~55%
With serum samples, yield is 15-20% With plasma samples, yield is
less as compared to plasma for a around 55% for a given blood
similar blood draw volume draw volume

Serum or plasma? An old question waiting for new answers


There is an ongoing debate on what type of sample a clinical laboratory should use. While serum is still considered the gold
standard and remains the required sample matrix for some assays, laboratories must consider turn-around time, which is an
important metric for laboratory performance and, more importantly, plays a critical role in patient care. In addition, a body
of evidence emphasises the choice of plasma samples in order to prevent modifications of some measurements due to the
coagulation process and related interferences. Advantages and disadvantages of serum and plasma are discussed on the basis of
current literature and evidence. In addition, data are provided on the current utilisation of the matrix (serum or plasma) in Italy
and in other countries. Finally, a rational for a possible shift from serum to plasma is provided.11

1. Jones BA, Bekeris LG, Nakhleh RE, et al. Physician satisfaction with clinical laboratory services: a College of American Pathologists Q-probes study of 138 institutions. Arch Pathol Lab Med. 2009;133(1):38–43.
doi: 10.1043/1543-2165-133.1.38.
2. Jones BA, Walsh MK, Ruby SG. Hospital nursing satisfaction with clinical laboratory services: a College of American Pathologists Q-Probes study of 162 institutions. Arch Pathol Lab Med. 2006;130(12):1756–61.
3. Akl P, Blick KE. A case of false-positive test results in a pregnant woman of unknown HIV status at delivery. Lab Med. 2014;45(3):259–63. doi: 10.1309/LMAAGVXK05LUWOQN.
4. Zweig MH, Glickman J, Csako G. Analytical interference caused by incompletely clotted serum specimens. Clin Chem. 1994;40(12):2325–6.
5. Nosanchuk JS, Combs B, Abbott G. False increases of troponin I attributable to incomplete separation of serum. Clin Chem. 1999;45(5):714.
6. Mannu GS, Bhalerao A. Unrecognized pseudohyperkalaemia in essential thrombocythaemia. JRSM Short Rep. 2011;2(11):85.
7. Nomura M, Nakasuji M, Nakamura M, Imanaka N, Tanaka M, Kawashima H. Pitfall in intraoperative electrolyte management for a patient with pseudohyperkalemia caused by thrombocytosis. Masui.
2009;58(10):1300–2.
8. Narayanan S, Guder WG. Preanalytical Variables and Their Influence on the Quality of Laboratory Results. EJIFCC. 2001;13(1):9–12.
9. Schlueter K, Nauck M, Petersmann A, Church S. Using BD Laboratory Consulting Services™ to understand the impact of the preanalytical phase on sample quality and safety, a multi country perspective. Biochem
Med (Zagreb). 2013;23(2):224.
10. Wisser D, van Ackern K, Knoll E, Wisser H, Bertsch T. Blood loss from laboratory tests. Clin Chem. 2003;49(10):1651–5.
11. Plebani M, Banfi G, Bernardini S, et al. Siero o plasma? Un quesito non nuovo che attende risposte nuove. Biochim Clin. 2018;42(4):277–351.

19
Venous blood sampling
Plasma analysis
Lithium Heparin/Sodium Heparin
BD Vacutainer® plasma tubes for clinical chemistry are
available with spray-dried sodium heparin or lithium heparin
additives. Heparin acts as an anticoagulant by creating a
complex with antithrombin III. This complex inhibits thrombin
and the activated factor X and thus prevents coagulation.
The lithium heparin in BD Vacutainer® tubes is spray dried
onto the inner walls to achieve the best possible solubility. For
clinical chemistry, lithium heparin is generally preferred over
sodium heparin.

Tube mixing Centrifugation conditions


To avoid micro-clotting, mix the BD Vacutainer Heparin Tube
®
≤ 1,300 g for 10 minutes at 18-25°C
with 8-10 inversions immediately after the blood sample has
been taken. Further information
Clinical and technical information is available on request.

BD Vacutainer® Heparin Tubes

Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

367884 4.0 13 x 75 Lithium heparin None PET Paper BD HemogardTM

367871 4.0 13 x 75 Sodium Heparin None PET Paper BD HemogardTM

367886 6.0 13 x 100 Lithium heparin None PET Paper BD HemogardTM

367878 6.0 13 x 100 Sodium Heparin None PET Paper BD HemogardTM

367874 10.0 16 x 100 Lithium heparin None PET Paper BD HemogardTM

All tubes are supplied in boxes of 100 / cases of 1,000


* Partial-draw tube

20
Venous
blood

Venous blood sampling sampling

Plasma analysis
BD Vacutainer® BarricorTM Plasma Blood
Collection Tube
BD Vacutainer® BarricorTM is a revolutionary new blood collection
tube that delivers a consistently fast, clean and high-quality plasma
sample to enable the most accurate results.
The design complements the BD Vacutainer® evacuated blood
collection tubes, and continues the BD heritage of ensuring best
practice in the collection, transportation and processing of blood
samples.
BD BarricorTM product features have been designed to ensure
optimal performance. The cutting-edge mechanical separator
speeds up throughput and enables workflow optimisation by
harnessing the power of plasma.

Accuracy Quality
BD Barricor™ is an innovative technology that provides greater The BD Barricor™ mechanical separator technology
confidence in the accuracy of laboratory results across a broad delivers a leading-edge collection and analytical process
range of analytes enabling clinicians to act on reliable and by eliminating separator artefacts that may interfere
credible results to deliver cutting-edge care and service. with analyte testing and that could lead to instrument
downtime. This innovation helps deliver the highest
• P rolonged stability and reduced interference for enhanced
diagnostic quality and patient care.
therapeutic drug monitoring1
• S uperior sample quality than plasma gel tubes – 47%
• L onger stability of analytes versus current plasma gel
fewer platelets count versus BD Vacutainer® PST™ II
separator tubes and reduced temperature sensitivity in
tubes3
storage
• P ositive impact on key performance indicators such as
haemolysis rate4

Fast diagnosis Efficiency


BD Barricor™ delivers a faster time–to–result for all patients BD Barricor™ has been designed to ensure optimal
with no clotting time and a reduction in centrifugation time of performance across the sample and laboratory workflow,
up to 7 minutes. providing opportunities for improving the total cost of
operations.
• S eparation in 3 minutes at 4000g2
• Greater range of analytes can be tested in a single tube;
• R
 eduction of turnaround and reliable TAT target
achievements • E liminates the risk of gel contamination of the sampling
probe, causing probe blockages leading to analyser
downtime and maintenance.

1. Schrapp A, Mory C, Duflot T, Pereira T, Imbert L, Lamoureux F. The right blood collection tube for therapeutic drug monitoring and toxicology screening procedures: Standard tubes, gel or mechanical separator?
Clin Chim Acta. 2019;488:196–201.
2. BD White Paper VS9192: VS9192: Evaluation of Analyte Performance (including cell count, plasma yield, visuals) at Various Centrifugation Conditions, 2016.
3. BD White Paper VS9195: Evaluation of Specimen Quality in BD Vacutainer® BarricorTM Tubes with Respect to Visual Observations and Cell Counts in Plasma as Compared with BD Vacutainer® PSTTM II Tubes, 2016.
4. Ramakers C. BD Vacutainer® Barricor tube in the emergency department: reduced hemolysis rates using partial draw tubes with reduced vacuum. Clin Chem Lab Med. 2018;56(2):e31–e32.

21
Venous blood sampling
Plasma analysis
Tube mixing Further information
To avoid micro-clotting, mix the BD BarricorTM tube with 8-10 BD BarricorTM is supported by a constantly growing knowledge
inversions immediately after the blood sample has been base. As of January 2019, it includes:
taken.
• Over 10 peer-reviewed manuscripts
Centrifugation conditions
• 28 posters presented at international conferences
4,000 g for 3 minutes
• 25 BD white papers
3,000 g for 5 minutes
Ask your local BD Specimen management representative for
2,500 g for 7 minutes these and further technical information on BD BarricorTM.
1,850 g for 10 minutes A series of webinars on BD BarricorTM and the enhancement
that it brought to labs across Europe are available on this
For infectious disease testing, centrifuge at 3,000 g for 10
website:
minutes1.
http://lp.bd.com/Barricor-webinars.html
See www.bd.com/ifu

BD Vacutainer® BarricorTM Tubes


Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

365050 3.0 13 X 75 Lithium heparin Mechanical separator** PET Paper BD Hemogard™

365053 3.5 13 X 100 Lithium heparin Mechanical separator** PET Paper BD Hemogard™

365049 4.5 13 x 100 Lithium heparin Mechanical separator** PET Paper BD Hemogard™

365056 5.5 13 X 100 Lithium heparin Mechanical separator** PET Paper BD Hemogard™

All tubes are supplied in boxes of 100 / cases of 1,000


* Partial-draw tube
** Mechanical separator: thermoplastic elastomer (TPE) and high-density polypropylene (HDPP)

1. BD White Paper VS9236: Comparison of BD Vacutainer® Barricor™ Tubes with BD Vacutainer® PST™ II, SST™ II and Serum Tubes for Selected Diagnostic Infectious Disease Marker Assays, 2016.

22
Venous
blood

Venous blood sampling sampling

Plasma analysis
BD Vacutainer® PSTTM II Tubes
These tubes contain an inert gel barrier and spray-dried
lithium heparin additive. The inert barrier separates the
plasma from the blood cells during centrifugation, preventing
contamination of the plasma. For example, in plasma certain
analytes such as potassium, phosphorus and glucose should
be separated from the cells within a few hours, otherwise the
results will be significantly impacted. Using BD PSTTM II
tubes, routine analytes in clinical chemistry such as potassium
are still stable after 24 hours storage at 2-8ºC. Clinical
evaluation of special chemistries such as therapeutic drugs, Effects of temperature
proteins, peptides, steroids and vitamins demonstrates a high BD Vacutainer® PSTTM II tubes should be stored at 4-25°C and
degree of stability within BD PSTTM II tubes1-3. protected from direct sunlight during storage. Cooling of the
tube by or during centrifugation can affect the movement.
BD Vacutainer® PSTTM II tubes enable faster centrifugation
The optimum separation of sediment and plasma is achieved
times of 5 minutes at 3,000 g.
at a temperature of 20-25°C.
The main advantages of gel tubes versus non-gel tubes are:
Tube mixing
• Stable barrier between plasma and clotted blood during To avoid micro-clotting, mix the BD Vacutainer® PSTTM II tube
transportation and storage, therefore better analyte with 8-10 inversions immediately after the blood sample has
stability. been taken.
• Better sample quality. Centrifugation conditions
• Workflow optimisation: short centrifugation time, sample 1,300-2,000 g for 10 minutes at 18-25°C
processing and archiving in the primary tube. or alternatively, according to BD study VS 75134
• No requirement for secondary tubes, reducing the possibility 3,000 g for 5 minutes at 18-25°C
of misidentification. Further information
Clinical and technical information is available on request.

BD Vacutainer® PSTTM II Tubes

Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

367374 3.0 13 x 100 Lithium heparin Gel PET Paper BD HemogardTM

All tubes are supplied in boxes of 100 / cases of 1,000

1. BD White Paper VS5919: Comparison of BD Vacutainer® PSTTM II Plastic Tubes to BD Vacutainer PSTTM Plastic Tubes for 22 Routine Chemistry Analytes and 3 Cardiac (STAT) Analytes, 2003.
2. BD White Paper VS5925: Analyte Stability Supports Extended Use of Plasma Collected in BD Vacutainer PSTTM II Plastic Tubes, 2001.
3. BD White Paper VS7597: A comparative evaluation of PST II with Lithium Heparin Plus and Serum Plus for selected hormones, therapeutic drugs, tumor markers and other chemistry analytes, 2008.
4. BD White Paper VS7513: Performance of BD Vacutainer® PSTTM II PLUS Tubes at Four and Five Minute Centrifugation Times, 2002.

23
Venous blood sampling
Haematology
EDTA
EDTA (ethylenediaminetetraacetic acid salts) are used to
anticoagulate whole blood for haematological investigations,
as the cellular components of the blood are particularly well
preserved by EDTA. The anticoagulation is achieved by the
EDTA forming complexes with metal ions such as calcium,
therefore inhibiting the coagulation cascade. Anticoagulation
with EDTA is irreversible.
The EDTA concentration in BD Vacutainer® tubes is 1.8 mg/mL
of whole blood, as recommended by the International Council
Society of Haematology (ICSH)1. The ICSH recommends
dipotassium EDTA salt (K2EDTA) for haematological
investigation. BD Vacutainer® plastic (PET) tubes are available Tube mixing
with spray dried K2EDTA and K3EDTA. To avoid micro-clotting, mix the EDTA tube with 8-10 inversions
immediately after the blood sample has been taken.
Further information
Clinical and technical information is available on request.
BD Vacutainer® K2EDTA Tubes
Alternate Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
Cat. no. (mL)

367841 368841 2.0* 13 x 75 K2EDTA None PET Paper BD HemogardTM

367856 368856 3.0* 13 x 75 K2EDTA None PET Paper BD HemogardTM

367861 368861 4.0 13 x 75 K2EDTA None PET Paper BD HemogardTM

367863 367864 6.0 13 x 100 K2EDTA None PET Paper BD HemogardTM

367525 10.0 16 x 100 K2EDTA None PET Paper BD HemogardTM

BD Vacutainer® K3EDTA Tubes

Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

364662 3.0* 13 x 75 K3EDTA None PET Block BD HemogardTM

368270 4.0 13 x 75 K3EDTA None PET Block BD HemogardTM

All tubes are supplied in boxes of 100 / cases of 1,000


* Partial-draw tube

1. Recommendations of the International Council for Standardization in Haematology for Ethylenediaminetetraacetic Acid Anticoagulation of Blood for Blood Cell Counting and Sizing. International Council for
Standardization in Haematology: Expert Panel on Cytometry. Am J Clin Pathol. 1993;100(4):371–2.

24
Venous
blood

Venous blood sampling sampling

Glucose analysis
Glucose and lactate determination
BD Vacutainer® Glucose Tubes are available in sodium
fluoride/potassium oxalate, sodium fluoride/sodium EDTA or
sodium fluoride/sodium heparin additive combinations.
Glucose values in unpreserved blood samples decrease quickly
after collection as glucose is metabolised by the blood cells.
The fluoride additive stops the enzymatic activity of the
glycolytic pathway.

HbA1c determination
One advantage of the fluoride/EDTA tube over the fluoride/
oxalate tube is that the HbA1c marker can be determined
from the same tube, so there is no need to take an additional
sample. Centrifugation conditions

Tube mixing ≤1,300 g for 10 minutes at 18-25°C

To avoid micro-clotting, mix the BD Vacutainer® Glucose Tube Further information


with 8-10 inversions immediately after the blood sample has
been taken. Clinical and technical information is available on request.

BD Vacutainer® Tubes for Glucose and Lactate Determination

Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

Sodium fluoride (1.5 mg/mL) /


367587 2.0* 13 x 75 None PET Paper BD HemogardTM
Disodium EDTA (3.0 mg/mL)

Sodium fluoride (1.5 mg/mL) /


368521 4.0 13 x 75 None PET Paper BD HemogardTM
Disodium EDTA (3.0 mg/mL)

Sodium fluoride (2.5 mg/mL) /


367922 4.0 13 x 75 None PET Paper BD HemogardTM
Potassium oxalate (2.0 mg/mL)

Sodium fluoride (2.5 mg/mL) /


367925 6.0 13 x 100 None PET Paper BD HemogardTM
Potassium oxalate (2.0 mg/mL)

All tubes are supplied in boxes of 100 / cases of 1,000

* Partial-draw tube
25
Venous blood sampling
Speciality tubes
Trace element determination
BD Vacutainer® Trace Element Tube Contamination Upper Limits
BD Vacutainer tubes for trace element determination contain
® Analyte Glass µg/L PET µg/L Analyte Glass µg/L PET µg/L

controlled amounts of trace elements for trace element Antimony 0.8 -* Lead 2.5 0.3
Arsenic 1.0 0.2 Magnesium 60 40
analysis. Maximum concentrations are defined for the trace Cadmium 0.6 0.1 Manganese 1.5 1.5
elements antimony, arsenic, lead, chromium, iron, cadmium, Calcium 400 150 Mercury** - 3.0
calcium, copper, magnesium, manganese, mercury, selenium Chromium 0.9 0.5 Selenium - 0.6
Copper 8.0 5.0 Zinc 40 40
and zinc that could be extracted by blood from the tube itself Iron 60 25
or the stopper. * BD Vacutainer® trace element PET tubes should not be used for antimony
testing.
Every production batch is checked and only released if the
** Water extraction analysed by cold vapour, all others ICP-MS
given maximum value is not exceeded. The values given take
into account the use of a straight BD needle.

BD Vacutainer® Tubes for Trace Element Determination

Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

368380 6.0 13 x 100 Silica (clot activator) None PET Paper BD HemogardTM

368381 6.0 13 x 100 K2EDTA None PET Paper BD HemogardTM

All tubes are supplied in boxes of 100 / cases of 1,000


Blood group determination

The anti-coagulant Acid Citrate Dextrose (ACD) is used for


erythrocyte conservation. ACD is available in two solutions, A
and B, each with different mixture ratios.

Anti-coagulant ACD solution A ACD solution B


Na3 citrate 3.30 mg/mL 1.89 mg/mL
Citric acid 1.20 mg/mL 0.69 mg/mL
Dextrose 3.68 mg/mL 2.10 mg/mL
Potassium sorbate 0.03 mg/mL 0.03 mg/mL

The figures represent the final concentration in the blood in each case.

BD Vacutainer® Tubes for Blood Group Determination


Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

364606 8.5 16 x 100 ACD solution A None Glass Paper Conventional

364816 6.0 13 x 100 ACD solution B None Glass Paper Conventional

All tubes are supplied in boxes of 100 / cases of 1,000

26
Venous
blood

Venous blood sampling sampling

ESR
BD Vacutainer® SeditainerTM Tubes
Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

366676 1.8 8 x 100 Sodium citrate (0.105 M) None Glass Paper Conventional

BD SeditainerTM System
The BD SeditainerTM tubes are designed for erythrocyte sedimentation rate (ESR)
determination without using sedimentation pipettes. The blood is taken directly
into the BD SeditainerTM tubes and mixed by inversion 8-10 times.

BD Vacutainer® Manual ESR Tubes

Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

367740 1.6 13 x 75 Sodium citrate (0.129 M) None Glass Paper BD HemogardTM

All tubes are supplied in boxes of 100 / cases of 1,000

27
Cell and biomarker preservation
BD CPTTM Blood Collection Tubes
BD CPTTM (Cell Preparation Tube)
The BD CPTTM contains FICOLLTM* and is a one-step system
that provides a simple method for isolating peripheral blood
mononuclear cells (PBMCs) - lymphocytes and monocytes
from whole blood.
The tube provides a sample-to-yield solution, eliminating
stages of blood transfer, preparation of FICOLLTM and manual
gradient separation. Waiting time is significantly reduced as
centrifugation can be carried out with the brakes enabled.
The tube can yield up to 1.3 million lymphocytes and
monocytes per mL of whole blood with centrifugation times
of 15 or 20 minutes. The BD CPTTM tube enables:
• Preparation and consistency
- Standardised process when compared to manual
FICOLLTM gradient separations
- Reproducibility between sample preparations and
technical operators
- Less blood exposure for laboratory staff
• Faster separations
The BD CPTTM tube is CE marked for in vitro diagnostic use.
- Blood draw to centrifuge - FICOLLTM is contained in the
tube enabling fast gradient separation Further information
- Reduce waiting times during centrifugation with brakes
enabled Clinical and technical information is available on request.

• Post separation Centrifugation conditions


- The gel barrier provides clear cell separation and prevents
Sodium Heparin 1,500-1,800 g for 15 minutes at 18-25°C
re-mixing
Sodium Citrate 1,500-1,800 g for 20 minutes at 18-25°C
- Transport of separated sample can be used in the primary
BD CPT™ tube
- Cells are stable in the primary tube for up to 24 hours,
depending on downstream application

BD Vacutainer® CPTTM Tubes


Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

Sodium citrate 0.45 mL


362781 4.0 13 x 100 Gel Glass Transparent Conventional
0.1 M/1.0 mL FICOLLTM

Sodium citrate 1.0 mL


362782 8.0 16 x 125** Gel Glass Transparent Conventional
0.1 M/2.0 mL FICOLLTM

Sodium heparin 132 USP Units


362780 8.0 16 x 125** Gel Glass Transparent Conventional
in 1.0 mL PBS/2.0 mL FICOLLTM

All tubes are supplied in boxes of 60

* FICOLL is a registered trademark of GE Healthcare Companies.


** Please note: These tubes are longer than conventional blood collection tubes. Please ensure that the tubes are free to swing
when placing them into the centrifuge.

QC materials for BD-Sedi 20TM & BD Sedi-40TM control ranges. DUO-MIX and ACCU-SED® are trademarks of Eliteh Group BV.

28
Cell and
biomarker

Cell and biomarker preservation preservation

BD PPTTM Blood Collection Tubes


BD PPTTM (Plasma Preparation Tube)
The BD PPTTM tube is used to separate undiluted plasma
from whole blood for molecular diagnostic test methods.
These methods include, but are not limited to, polymerase
chain reaction (PCR) or branched DNA (bDNA) amplification
techniques. The BD PPTTM tube is also applicable to other MDx
analyses where an undiluted plasma specimen is required. The
BD PPTTM tube ensures:
• Safe handling of infectious samples
The user is not exposed to blood samples enclosed in the
BD Vacutainer® tube. Plasma is prepared in the closed
BD Vacutainer® tubes that can be directly transported,
eliminating the need for aliquoting from primary
BD Vacutainer® tube to secondary container and re-
labelling.
• Plasma quality is maintained
The gel barrier prevents plasma from coming in contact with
red blood cells to maintain stability of the plasma. Viral load
will be stable for:
6 hours - whole blood at room temperature
24 hours - separated plasma at room temperature Further information
5 days - separated plasma refrigerated at 4ºC. Clinical and technical information is available on request.
Plasma may be stored frozen in situ in the BD PPT tube.
TM

However, freezing plasma in situ in BD PPTTM tubes may be Centrifugation conditions


prohibited for some assays and the assay manufacturer’s 1,100 g for 10 minutes at 18-25°C
guidelines should be consulted.
The BD PPTTM tube is CE marked for in vitro diagnostic use.

BD Vacutainer® PPTTM Tubes

Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

362795 5.0 13 x 100 K2EDTA Gel PET See thru BD HemogardTM

362799 8.5 16 x 100 K2EDTA Gel PET See thru BD HemogardTM

All tubes are supplied in boxes of 100 units/cases of 1,000

29
Cell and biomarker preservation
BDTM P100 Tubes (for stabilising proteins)
BDTM P100 Plasma Protein Preservation Tubes
The BDTM P100 tube is a plasma protein preservation tube
that contains K2EDTA anticoagulant and a broad spectrum
protease inhibitor cocktail optimised for human blood. The
BDTM P100 tube also features a mechanical separator which
provides high-quality plasma suitable for many downstream
protein analysis platforms including mass spectrometry and
immunoassays.
The blend of broad spectrum protease inhibitors in the
The BDTM P100 plasma protein tube is for research use only.
BDTM P100 tube has been specifically developed and
Not for use in diagnostic procedures.
optimised for human plasma to ensure the broadest range of
plasma proteins are stabilised.
Further information
The separator provides a solid barrier between plasma and
Clinical and technical information is available on request.
cellular material, ensuring a significant reduction in cellular
contamination to further increase the stability of the plasma Mechanical plasma separator (366448 only)
proteins.

Centrifugation Blood collection


set
For best sample quality, the centrifugation of the BD P100TM
Closure
tube should be performed in a swing-out centrifuge as soon as Non-patient stopper
possible after the blood sample has been collected. Use of a cannula,
piercing
fixed 45º angle rotor is possible. the closure
stopper
Optimum centrifugation conditions for 8.5 mL tube:
2,500 g for 20 minutes Tube holder
Plasma
mechanical
If 2,500 g cannot be achieved: separator
1,600 g for 30 minutes or
1,100 g for 30 minutes
Optimum centrifugation conditions for 2.0 mL tube:
1,000-3,000 g for 10 minutes
Before After
centrifugation centrifugation

BDTM P100 Tubes

Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

366422 2.0 13 x 75 K2EDTA/Protease inhibitor None PET Paper BD HemogardTM

Mechanical
366448 8.5 16 x 100 K2EDTA/Protease inhibitor PET Paper BD HemogardTM
separator*

All tubes are supplied in boxes of 24


* Mechanical separator: PET, TPE and LDPE

30
Cell and
biomarker

Cell and biomarker preservation preservation

BDTM P800 Tubes


BDTM P800 (Plasma GLP-1, GIP, Glucagon
and OXM Preservation Tubes)
The BDTM P800 tube contains a proprietary cocktail of
protease, esterase and dipeptidyl peptidase IV (DPP-IV)
inhibitors that immediately solubilises during blood collection.
The BDTM P800 tube provides preservation of the incretin
peptides released during feeding - glucagon like peptide-1 Stability
(GLP-1), gastric inhibitory peptide (GIP), glucagon and
oxyntomodulin (OXM)1. The incretin peptides are associated The stability of the peptides in BDTM P800 tubes in
with metabolic diseases, such as type 2 diabetes and obesity. comparison to BD Vacutainer® EDTA Tubes for routine
measurements is set out in the following table:
Centrifugation conditions
2.0 mL tubes: 1,100-1,300 g for 10 minutes
Peptides T ½ EDTA (h) T ½ P800 (h)
8.5 mL tubes: 1,100-1,300 g for 20 minutes
GLP-1 (G36A) 4-24* > 96
GLP-1 (G37) 4-18 > 96
Further information GIP (1-42) 5-20 > 96
OXM (1-37) < 24 > 72
Clinical and technical information is available on request.
Glucagon 5-20 > 45
The BDTM P800 tube is for research use only. Not for use in
diagnostic procedures. * Stable for up to 12 hours +/- 3 hours when EDTA tube is on ice
Half-life, hours (at room temperature, unless specified).

BDTM P800 Tubes

Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

K2EDTA/Protease, esterase and


366420 2.0 13 x 75 None PET Paper BD HemogardTM
DPP-IV inhibitor

K2EDTA/Protease, esterase and


366421 8.5 16 x 100 None PET Paper BD HemogardTM
DPP-IV inhibitor

All tubes are supplied in cases of 100


Proprietary
cocktail that
immediately
solubilises
during blood
collection

31
Cell and biomarker preservation
PAXgene® Blood RNA System
PAXgene® Blood RNA System
The PAXgene® blood RNA tube (IVD) was developed by
PreAnalytiX, a joint venture between QIAGEN and BD. The
PAXgene® blood RNA system consists of the PAXgene® blood
RNA tube and the PAXgene® blood RNA isolation kit available
from QIAGEN.
The PAXgene® blood RNA tube contains a proprietary reagent
that immediately stabilises cellular RNA. The PAXgene® blood
RNA tube ensures:
• Immediate stabilisation of cellular RNA in whole blood
The cellular RNA will be stable in the PAXgene® tube for:
3 days – whole blood at room temperature (18-25°C)
5 days – refrigerated whole blood (2-8°C)
8 years – frozen whole blood (–20 and –70°C) • Increased traceability
• RNA yield The PAXgene® blood RNA tube has a human readable and
The yield, dependent upon the sample and the RNA 2D barcode label. Each tube has a unique identification
isolation kit, is ≥ 3 µg for > 95% of the samples (healthy code that can be associated to the patient blood specimen
subjects with a leukocyte count of 4.8 – 11 x 106/mL) For more information please visit www.PreAnalytiX.com.
• RNA quality The PAXgeneTM blood RNA system is CE marked for in vitro
The A260/A280 ratio is 1.8-2.2 for 95% of all samples. Genomic diagnostic use.
DNA contamination is ≤ 1% in ≥ 95% of all samples
Further information
• Stabilisation of miRNA
The PAXgene® blood miRNA kit*, is available from QIAGEN Clinical and technical information is available on request.

PAXgene® Blood RNA Tubes

Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

Paper with
762165 2.5 16 x 100 Proprietary None PET BD HemogardTM
2D barcode

All tubes are supplied in cases of 100


*The PAXgene® blood miRNA kit is for research use only (RUO)

Proprietary
reagents that
immediately
stabilise cellular
RNA

32
Cell and
biomarker

Cell and biomarker preservation


preservation

PAXgene® Blood ccfDNA System


NEW
PAXgene® Blood DNA System
The PAXgene® blood ccfDNA tube (IVD) was developed by
PreAnalytix, a joint venture between QIAGEN and BD.
The PAXgene® blood ccfDNA tube is a plastic, evacuated tube
intended for the collection, storage and transport of human
blood and stabilisation of DNA. It is a closed tube used to
prepare circulating, cell-free DNA (ccfDNA) from plasma and
genomic DNA (gDNA) from nucleated cellular fraction, and
used with molecular test methods that require ccfDNA or
gDNA.
The PAXgene® blood ccfDNA tube ensures: • Workflow ease
• Immediate stabilisation of circulating, cell-free DNA, and Simplified centrifugation protocols with an optional second
genomic DNA for the following duration and temperature centrifugation at the same speed and force to optimise
ranges: workflow efficiencies at 1,600 x g for 10 minutes with
7 days in whole blood at 2-30°C medium brakes.
1 day in whole blood at 37°C Performance characteristics established with 18S ribosomal
• Analysis of methylated markers and DYS14 Y-chromosomal ccfDNA fragments in plasma.
A unique non-crosslinking stabilisation chemistry containing For more information please visit www.PreAnalytix.com
a proprietary formulation that preserves circulating, cell-free
DNA without cross-linking challenges to optimise sensitivity The PAXgene® blood ccfDNA tube (IVD) is CE marked for in
and specificity for genetic biomarker downstream analysis*. vitro diagnostic use.

• ccfDNA & gDNA Further information


Extract both ccfDNA and gDNA from one tube after
Clinical and technical information is available on request.
centrifugation for parallel analyte analysis.
• High-quality analytes for downstream analysis
Compatibility of NGS and qPCR quantification methods with
ccfDNA and DNA samples

PAXgene® Blood ccfDNA Tubes

Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

Paper with
768165 10.0 16 x 100 Proprietary None PET BD HemogardTM
2D barcode

All tubes are supplied in cases of 100


*Users must validate use of product for their specific molecular diagnostic assay.

1. Yi J, Warunek D, Craft D. Degradation and Stabilization of Peptide Hormones in Human Blood Specimens. PLoS One. 2015;10(7):e0134427.

33
Cell and biomarker preservation
PAXgene® Blood DNA System
PAXgene® Blood DNA System
The PAXgene® blood DNA tube (IVD) was developed by
PreAnalytiX, a joint venture between QIAGEN and BD. The
performance of the PAXgene® blood DNA tube has been
verified with automated and manual DNA isolation kits
available from QIAGEN using magnetic bead, silica membrane
and precipitation technologies.
The PAXgene® blood DNA tube contains a proprietary EDTA
formulation that immediately stabilises intracellular DNA. The
PAXgene® blood DNA tube ensures sufficient DNA quantity
and quality for molecular diagnostic assays that require DNA
from whole blood.

Documented DNA stability and performance data


DNA samples purified from the 2.5 mL draw volume tube will
have a ratio (A260/A280) of 1.7-1.9 and a DNA concentration of For more information please visit
≥ 12.5 ng DNA/µl eluate for 95% of samples and ensure DNA www.PreAnalytix.com.
stability after blood collection for:
The PAXgene® blood DNA tube (IVD) is CE marked for in vitro
14 days at room temperature (18-25°C) diagnostic use.
refrigerated for 28 days (2-8°C)
3 days at 35ºC Further information

Increased traceability Clinical and technical information is available on request.

The PAXgene® blood DNA tube (IVD) has a human readable


and 2D barcode label. Each tube has a unique identification
code that can be associated with the patient blood specimen.

PAXgene® Blood DNA Tubes

Draw volume
Cat. no. Size (mm) Additive Separator Material Label Cap closure Cap colour
(mL)

Paper with
761165 2.5 13 x 75 K2EDTA None PET BD HemogardTM
2D barcode

All tubes are supplied in cases of 100

Proprietary
formulation that
immediately
stabilises
intracellular
DNA

34
Blood

Blood collection
collection

Push button safety blood collection sets


BD Vacutainer® UltraTouchTM Push Button Blood
Collection Set
The BD Vacutainer® UltraTouchTM Push Button blood
collection set employs patented PentaPointTM comfort
5-bevel needle technology. Studies have shown that this
design helps reduce the chance of a painful injection by
creating a flatter, thinner surface to help penetrate the
skin with significantly greater ease.1 This new safety device
has been shown to reduce penetration forces by up to 32
percent when compared to another leading blood collection
set.2
In addition, its exclusive BD RightGaugeTM, Ultra-Thin wall
technology allows for better blood flow due to the needle’s
larger inner diameter. Therefore, clinicians can select a smaller
gauge needle without sacrificing sample quality.
This technology can also improve tube fill time by up to 50%
when using the same gauge (a standard 23-G needle vs the
BD Vacutainer® UltraTouch™ Push Button needle).3 Comfort Speed
The BD Vacutainer® UltraTouch™ Push Button blood collection Ultra-thin wall Thin wall
set brings healthcare workers greater confidence and the 1
ability to know they can use the needle gauge that is most 4 23 G 0.600

appropriate for their patients with improved efficiency. 5


2 0.533 0.381

Further information 3
25 G 0.500
PentaPoint™
BD recommends for all needles without an integrated holder needle tip 0.406 0.305
that a BD Vacutainer® Holder be used. All measurements are in mm

Clinical and technical information is available on request.

The experience
Reduce
Lower pain compared to needlestick injury
traditional blood collection sets

Improving Faster fill time In-vein confirmation


difficult compared to results in ease of use and
venous access traditional blood confidence during venous
collection sets blood collection

1. Hirsch L, Gibney M, Berube J, Manocchio J. Impact of a modified needle tip geometry on penetration force as well as acceptability, preference, and perceived pain in subjects with diabetes. J Diabetes Sci Technol.
2012;6(2):328–35.
2. Mouser A, Uettwiller-Geiger D, Plokhoy E, Berube J, Jha Ahuja A, Stankovic AK. Evaluation of Pain and Specimen Quality by Use of a Novel 25-Gauge Blood Collection Set With Ultra-thin Wall Cannula and 5-Bevel
Tip Design. J Appl Lab Med. 2017;2(2):201–210.
3. BD White Paper VS9249: BD Vacutainer® Push Button Blood Collection Set Tube Fill Time, 2016.
35
Blood

Safety blood collection sets


Blood collection
collection

Push button safety blood collection sets


BD Vacutainer®® UltraTouchTM Push Button Blood Collection Sets
BD Vacutainer UltraTouchTM Push Button Blood Collection Sets
Cat.no.
no. Alternate Size Needle length With LuerWith Luer
Cat. Size Needle lengthLength Length
of tubing
of tubing adapter Colour
Colour code
code Box/Case
Box/Case
Cat. no. adapter

367393
367393 21 G (0.8 mm)
368684 21 G (0.8 mm) 19 mm 19 mm 178 mm
178 mm Yes Yes 50/200
50/200

367365
367365 21 G (0.8 mm)
368685 21 G (0.8 mm) 19 mm 19 mm 305 mm
305 mm Yes Yes 50/200
50/200

367392
367392 23 G (0.6 mm)
368686 23 G (0.6 mm) 19 mm 19 mm 178 mm
178 mm Yes Yes 50/200
50/200

367364
367364 23 G (0.6 mm)
368687 23 G (0.6 mm) 19 mm 19 mm 305 mm
305 mm Yes Yes oo 50/200
50/200

367391
367391 25 G (0.5 mm)
368688 25 G (0.5 mm) 19 mm 19 mm 178 mm
178 mm Yes Yes 50/200
50/200

367363
367363 25 G (0.5 mm)
368689 25 G (0.5 mm) 19 mm 19 mm 305 mm
305 mm Yes Yes 50/200
50/200

BD Vacutainer® UltratouchTM Push Button Blood


Collection Set with Pre-Attached Holder
With this safety blood collection set the holder is already pre-
NEW
attached, so it is not necessary to manually assemble the
needle and holder. This ready-for-use blood collection set is
individually packaged in a sterile blister.
This sterile closed system is ideally suited for taking of
samples using the BD BACTECTM blood culture bottles with
improved fill rate1.

BD Vacutainer® UltraTouchTM Push Button Blood Collection Sets with Pre-Attached Holder

Cat. no. Size Needle length Length of tubing Colour code Box/Case

368686 21 G (0.8 mm) 19 mm 178 mm 20/100

368689 21 G (0.8 mm) 19 mm 305 mm 20/100

368685 23 G (0.6 mm) 19 mm 178 mm 20/100

368688 23 G (0.6 mm) 19 mm 305 mm 20/100

368684 25 G (0.5 mm) 19 mm 178 mm 20/100

368687 25 G (0.5 mm) 19 mm 305 mm 20/100

1. White
1. BD BD White Paper
Paper VS9381:
VS9381: Evaluation
Evaluation of Draw
of Draw Volume,
Volume, Fill Time
Fill Time andand Fill Rate
Fill Rate for BACTEC™
for BD BD BACTEC™ Blood
Blood Culture
Culture Bottles
Bottles Using
Using the the BD Vacutainer®
BD Vacutainer® UltraTouch™
UltraTouch™ PushPush Button
Button Blood
Blood Collection
Collection Set Set Compared
Compared to to
the the BD Vacutainer®
BD Vacutainer® PushPush Button
Button Blood
Blood Collection
Collection Set,Set,
2019.2019.
39
36
Blood

Blood collection collection

Push button safety blood collection sets


BD Vacutainer® Push Button Blood Collection Set
The BD Vacutainer® Push Button blood collection set with
in-vein activation offers split-second protection against
needlestick injuries.
• Indication of successful venepuncture:
When the vein has been successfully penetrated, blood flows
immediately into the inspection chamber.
• Versatile:
For taking blood samples and for short-term infusions of up
to 2 hours.
• Single-handed activation possible:
Activating the safety mechanism with one hand allows
you to focus more attention on the patient and the
venepuncture site.
• Protection against needle injuries: Further information
When pressing the button, the needle is withdrawn
BD recommends for all needles without an integrated holder
straight from the vein and disappears permanently inside
that a BD Vacutainer® Holder is used.
the housing of the blood collection set. This provides an
extremely high level of protection against needle injuries1. Clinical and technical information is available on request.

BD Vacutainer® Push Button Blood Collection Sets

Cat. no. Size Needle length Length of tubing With Luer adapter Colour code Box/Case

367338 21 G (0.8 mm) 19 mm 178 mm Yes 50/200

367344 21 G (0.8 mm) 19 mm 305 mm Yes 50/200

367336 23 G (0.6 mm) 19 mm 178 mm Yes 50/200

367342 23 G (0.6 mm) 19 mm 305 mm Yes 50/200

367335 25 G (0.5 mm) 19 mm 178 mm Yes 50/200

367341 25 G (0.5 mm) 19 mm 305 mm Yes 50/200

1. Hotaling MA. retractable winged steel (butterfly) needle performance improvement project. JT Comm Qual Patient Saf. 2009;35(2):100–105.

37
Blood collection
Safety blood collection sets
BD Vacutainer® Safety-LokTM Blood Collection Set
The BD Vacutainer® Safety-LokTM blood collection set for
venous blood collection has a fully integrated safety shield,
which once activated, protects against needlestick injuries.
• Indication of successful venepuncture:
When the vein has been successfully penetrated, blood can
be seen in the device.
• Versatile:
For taking blood samples and for short-term infusions of up
to 2 hours.
• Single-handed activation possible:
Activating the safety mechanism with one hand allows
you to focus more attention on the patient and the
venepuncture site.
Further information
• Protection against needle injuries:
BD recommends for all needles without an integrated holder
Following successful venepuncture, the integrated safety
that a BD Vacutainer® Holder is used.
shield is pushed over the needle, covering it completely,
indicated by an audible click. Clinical and technical information is available on request.

BD Vacutainer® Safety-LokTM Blood Collection Sets with Luer Adapter


Cat. no. Size Needle length Length of tubing With Luer adapter Colour code Box/Case

367287 21 G (0.8 mm) 19 mm 178 mm Yes 50/200

367281 21 G (0.8 mm) 19 mm 305 mm Yes 50/200

367292 23 G (0.6 mm) 19 mm 178 mm Yes 50/200

367283 23 G (0.6 mm) 19 mm 305 mm Yes 50/200

367294 25 G (0.5 mm) 19 mm 178 mm Yes 50/200

367285 25 G (0.5 mm) 19 mm 305 mm Yes 50/200

BD Vacutainer® Safety-LokTM Blood Collection Sets without Luer Adapter

Cat. no. Size Needle length Length of tubing With Luer adapter Colour code Box/Case

367296 21 G (0.8 mm) 19 mm 305 mm No 50/200

367297 23 G (0.6 mm) 19 mm 305 mm No 50/200

367298 25 G (0.5 mm) 19 mm 305 mm No 50/200

38
Blood

Blood collection
collection

Safety blood collection needles


BD Vacutainer® EclipseTM SignalTM Blood Collection Needle
The BD Vacutainer® Eclipse™ Signal™ needle offers a
combination of proven robust safety technology with the
additional benefit of in-vein confirmation built into an integrated
ergonomic holder. This results in ease of use and confidence
during venous blood collection, increasing both healthcare
worker and patient safety.

Confirmation Reduced risk Minimal waste


BD InstaFlash TM
Blood droplet Efficiency in use
Needle Technology reduction and minimal
instantly signals technology draws waste with a
vein entry for blood away from simple peel
improved first stick the end of the to enable the
proficiency. needle sterile needle.

Reduce needlestick injuries


with thumb pad for single Minimal waste with a
step safety activation and simple peel to enable the
audible lock confirmation sterile needle

Safety shield aligned with


needle bevel with no further
visual checks


4 Immediate confirmation 5
of venous access is indicated
by the presence of blood in
the flashback chamber.

In-vein confirmation Ergonomics to improve


Reduce blood exposure with
results in ease of use and everyday use with anti-slip
blood exposure that pulls away
confidence during venous finger grips and ribbed
blood from the end of the
blood collection holder
needle

39
Blood collection
Safety blood collection needles
BD Vacutainer® EclipseTM SignalTM Blood Collection Needles with Integrated Holder

Cat. no. Size Needle length Colour code Box/Case

368835 21 G (0.8 mm) 25 mm 50/400

368836 22 G (0.7 mm) 25 mm 50/400

Further information
BD recommends for all needles without an integrated holder
that a BD Vacutainer® Holder is used.
Clinical and technical information is available on request.

BD Vacutainer® EclipseTM SignalTM Blood Collection Needles

Cat. no. Size Needle length Colour code Box/Case

368837 21 G (0.8 mm) 25 mm 50/500

368838 22 G (0.7 mm) 25 mm 50/500

40
Blood

Blood collection
collection

Safety blood collection needles


BD Vacutainer® EclipseTM Blood Collection Needle
The BD Vacutainer® EclipseTM safety needle for venous blood
sampling has a fully integrated safety shield, which once
activated, protects against needle stick injuries. This safety
shield is an integral part of the needle and its orientation
aligns with the needle bevel. The safety mechanism is
designed for single-handed activation. The fully integrated
safety shield engages over the needle with an audible click,
irreversibly locking with a triple closure mechanism.

Further information
BD recommends for all needles without an integrated holder
that a BD Vacutainer® Holder is used.
Clinical and technical information is available on request.

BD Vacutainer® EclipseTM Blood Collection Needles

Cat. no. Size Needle length Colour code Box/Case

368607 21 G (0.8 mm) 32 mm 48/480

368608 22 G (0.7 mm) 32 mm 48/480

BD Vacutainer® EclipseTM Blood Collection Needle with


Pre-Attached Holder
With this safety needle the holder is already pre-attached,
so it is not necessary to manually assemble the needle and
holder. This ready-for-use blood sample needle and holder is
individually packaged in a sterile blister.

BD Vacutainer® EclipseTM Blood Collection Needles with Pre-Attached Holder

Cat. no. Size Needle length Colour code Box

368650 21 G (0.8 mm) 32 mm 100

368651 22 G (0.7 mm) 32 mm 100

41
Blood collection
Blood collection needles

BD Vacutainer® needles can be used for multiple tube


samples. BD Vacutainer® needles are coated with silicone, a
low friction lubricant, ensuring smooth vein entry.
BD Vacutainer® needles are available in 20, 21 or 22 gauge
needle sizes.

Further information
BD recommends for all needles without an integrated holder
that a BD Vacutainer® Holder is used.
Clinical and technical information is available on request.

BD Vacutainer® Multi-Sample Needles

Cat. no. Size Needle length Colour code Box/Case

360215 20 G (0.9 mm) 38 mm 100/1,000

360214 20 G (0.9 mm) 25 mm 100/1,000

360213 21 G (0.8 mm) 38 mm 100/1,000

360212 21 G (0.8 mm) 25 mm 100/1,000

360211 22 G (0.7 mm) 38 mm 100/1,000

360210 22 G (0.7 mm) 25 mm 100/1,000

BD Vacutainer® Flashback Needle


The BD Vacutainer® flashback needle is built with the same quality as the multi-sample needle and includes in-vein confirmation.

Cat. no. Size Needle length Colour code Box/Case

365077 21 G (0.8 mm) 25 mm 50/1,000

365076 22 G (0.7 mm) 25 mm 50/1,000

42
Blood
collection

Blood collection
Accessories, adapters and holders
1
2

BD Vacutainer® Holder, BD Luer 3


Adapters and Adapters with pre-attached holders

1 The BD Vacutainer® Blood Transfer Device is a pre-


assembled and easy-to-use device designed with safety
in mind. It is used for needleless specimen transfer from
a syringe to an evacuated tube or blood culture bottle
4
and has a red colour-coded connection to provide easy
differentiation from other holder-based products.
2 The BD Vacutainer® Luer-LokTM Access Device is a pre-
assembled multi-sample BD Luer-LokTM. It is compatible
with female luer connections. It has a blue colour-coded
connection to provide easy differentiation from other
holder-based products.
4 The BD Vacutainer® luer adapter is a sterile device to be
3 The BD Vacutainer Holder is compatible with all
®
used with the BD Vacutainer® Holder. It is compatible with
BD Vacutainer® tubes and needles. The BD Vacutainer® female Luer connections. It has a blue colour-coded cap to
Holder is also compatible with the BD BACTECTM blood provide differentiation from other needles.
culture bottle.

BD Luer Adapters with Pre-Attached Holders


These single-use products are ready to use, sterile, packed individually

Alternate
Cat. no. Description Colour code Case
Cat. no.

364880 36488000 Blood Transfer Device (female luer) 198

364902 36490200 Luer-LokTM Access Device (male luer) 198

BD Vacutainer® Holder
Cat. no. Description Colour code Box/Case

BD Vacutainer® Holder is made of plastic and is compatible with tubes of


364879 250/1,000
13 mm and 16 mm diameter and BD BACTECTM blood culture bottles,

BD Vacutainer® Luer Adapter

Cat. no. Description Colour code Case

367290 BD Vacutainer® Luer Adapter 100/1,000

43
Blood collection
Stretch tourniquets

BD Vacutainer® Stretch Tourniquet


The BD Vacutainer® Stretch Tourniquet is latex and scent-
NEW free, and is packaged in an easy-to-use dispenser which is
also convenient for storage purposes.
Additional features include:
• Textured thermoplastic elastomer provides a better grip
• High visibility colours to increase contrast and minimise
the chances of tourniquets being left on the patient arm
or being incorrectly disposed of.

XTURE
IM TE
PROVED

BD Vacutainer® Stretch Tourniquets

Cat. no. Description Colour Box/Case

367198 25 new textured, single-use, latex-free tourniquets in one packaging unit, perforated for separation Blue 25/500

367205 100 new textured, single-use, latex-free tourniquets individually rolled and banded Blue 100/1000

367209 25 new textured, single-use, latex-free tourniquets in one packaging unit, perforated for separation Orange 25/500

367199 100 new textured, single-use, latex-free tourniquets individually rolled and banded Orange 100/1000

44
Capillary

Capillary blood sampling


blood
sampling

Safety lancets
Capillary sampling
The ergonomic design of the BD Microtainer®
Contact Activated safety single-use lancet enables it to be
held securely and the sampling point located precisely. The
lancet has been clinically demonstrated to minimise patient
discomfort and maximise blood flow.1,2
Its intuitive handling requires minimum training. The lancet
is activated by being pressed onto the sampling location,
minimising the influence of the user on puncture depth. The
Further information
sharp point then retracts automatically into the housing.
Clinical and technical information is available on request.
This lancet is available in three sizes: for a single drop of blood,
medium or large blood flow.

BD Microtainer® Contact-Activated Lancets

Cat. no. Piercing width and depth Blood volume Colour code Box/Case

366592 30 G x 1.5 mm One drop 200/2,000

366593 21 G x 1.8 mm Medium blood flow 200/2,000

366594 1.5 mm x 2.0 mm Large blood flow 200/2,000

BD SentryTM Safety Lancet


A single-use safety lancet available in two sizes. The
lancet has an automatic needle retraction to protect
healthcare workers from needlestick injuries and
prevents reuse. It is designed with a V-shaped finger
placement collar, natural-fit thumb pad and anti-slip
ridges for more confident handling. The lancet
ensures optimal skin contact area and has visual
guides for accurate targeting.

BD SentryTM Safety Lancets

Cat. no. Piercing width and depth Blood volume Colour code Box/Case

369528 28 G x 1.5 mm One drop 100/2,000

369523 23 G x 1.8 mm Medium blood flow 100/2,000

1. BD White Paper VS7499: A Comparison of BD Microtainer® Contact-Activated Lancet (Low Flow, purple) with BD Microtainer® GenieTM, LifeScan OneTouch® SureSoftTM Gentle, and SurgiLanceTM One-Step PLUS
Safety Lancets for Comfort, Ease of Use and Blood Volume, 2006.
2. BD White Paper VS7607: A Comparative Evaluation of the BD Microtainer® Contact-Activated Lancet (High Flow, Blue) with Other Market-leading Lancets for Blood Flow and Ease of Use during Finger Puncture
Procedures, 2008.

45
Capillary blood sampling
Safety lancets
Heelstick sampling
The BD Microtainer® QuikHeelTM safety single-use incision
lancet is for taking capillary blood samples from the heels of
premature, new-born babies and infants. When the button
is pressed, an extra-thin steel blade provides a fine, clean,
surgical cut and ensures a good flow of blood. The penetration
depth is pre-determined to protect against
bone infections and cannot be altered. The permanently
shielded blade excludes the possibility of injury or reuse.
The ergonomic design enables it to be held securely and the
Further information
piercing point located precisely. The incision lancets are sterile
and individually packed in blister packaging. Technical information is available on request.

BD Microtainer® QuikHeelTM Incision Lancets

Cat. no. Description Piercing depth Piercing width Colour code Box/Case

368100 Incision lancet for premature babies 0.85 mm 1.75 mm 50/200

368101 Incision lancet for newborn babies and infants 1.00 mm 2.50 mm 50/200

46
Capillary

Capillary blood sampling


blood
sampling

BD Microtainer® MAP Tubes


Process optimisation for capillary blood samples
BD Microtainer® MAP tubes are for collection, transport
and processing of capillary blood from infants, children,
geriatrics and emergency patients, whenever only the
smallest amounts of blood are required.
The BD Microtainer® MAP tube for automated processing
enables efficient workflow, both on the ward and in the
laboratory.
• A capillary blood tube with standard blood collection tube
dimensions (13 x 75 mm) and penetrable closure.
• Compatible with haematology analysers without the need • Easy to open with twist locking mechanism that ensures no
for a tube adapter. leakage.
• Three clearly visible fill markings ensure the correct sample • Colour marking for identification of the type of sample and
volume (250-500 µl). the correct positioning of the patient label.
• A standard label can be attached directly to the sample,
Further information
minimising the risk of misidentification due to missing or
incomplete labelling. Technical information is available on request.

BD Microtainer® MAP Tube

Cat. no. Description Closure Cap colour Box/Case

K2EDTA tube for haematology with


363706 BD MicrogardTM 50/200
full size blood collection tube, dimensions 13 x 75 mm

Automated
processing
enables efficient
workflow

47
Capillary blood sampling
BD Microtainer® Tubes
BD Microtainer®
BD Microtainer® tubes are for collection, transport and
processing of capillary blood from infants, children, geriatrics
and emergency patients, whenever only the smallest amounts
of blood are required.
In order to ensure tube identification, the tubes are marked
with the colour code that corresponds to the venous blood
collection tubes. There are fill marks on the tubes that ensure
the correct blood to additive ratio.

BD MicrogardTM Closure
The special design of the BD MicrogardTM safety closure
substantially reduces blood splashing after the tube has been
opened.
A larger diameter facilitates tube handling.
In combination with a tube extender, the BD Microtainer® tubes
with BD MicrogardTM closure fit into 13 x 75 mm racks.

Further information
Technical information is available on request.

BD Microtainer® Tubes with MicrogardTM Closure

Cat. no. Description Fill volume Closure Cap colour Box/Case

365974 K2EDTA tube for haematology 250-500 µl BD MicrogardTM 50/200

365965 Plasma tube with lithium heparin 200-400 µl BD MicrogardTM 50/200

365985 Plasma tube with separating gel and lithium heparin 400-600 µl BD MicrogardTM 50/200

Plasma tube with separating gel, lithium heparin and


365987 250-500 µl BD MicrogardTM 50/200
UV protection (amber tint for light sensitive tests like bilirubin)

365992 Glucose tube with sodium fluoride and Na2EDTA 400-600 µl BD MicrogardTM 50/200

365967 Serum tube with separating gel 400-600 µl BD MicrogardTM 50/200

Serum tube with separating gel and UV protection


365978 400-600 µl BD MicrogardTM 50/200
(amber tint for light sensitive tests like bilirubin)

365963 Serum tube with clot activator 250-500 µl BD MicrogardTM 50/200

48
Arterial
blood

Arterial blood sampling sampling

Preset blood gas syringes


BD PresetTM Safety Blood Gas Syringe
BD Critical Care Collection Syringes are available with the BD
EclipseTM safety-engineered needle, offering enhanced safety
for the healthcare worker. The safety shield is integrated and
is not an accessory to the needle. The needle bevel and safety
shield are in alignment, ensuring no extra manipulation. The
single-handed technique ensures no change in the collection
Further information
technique and the double-locking mechanism is both visually
and audibly confirmed for the healthcare worker. Clinical and technical information is available on request.

BD PresetTM Safety Blood Gas Syringes

Syringe Recommended Units of heparin* (IU)


Cat. no. Gauge Needle length Connection Tip cap
volume (mL) fill volume (mL) (per syringe/per mL of blood**)

364390 3.0 1.6 80/50 22 G (0.7 mm) BD EclipseTM 1” (25 mm) BD Luer-LokTM Hemogard style

364391 3.0 1.6 80/50 23 G (0.6 mm) BD EclipseTM 1” (25 mm) BD Luer-LokTM Hemogard style

364393 3.0 1.6 80/50 25 G (0.5 mm) BD EclipseTM 1” (25 mm) BD Luer-LokTM Hemogard style

Syringes supplied in cases of 100

BD PresetTM Blood Gas Syringe


The BD PresetTM syringe plunger can be preset to the recommended volume. As arterial blood fills the syringe, the residual air is
expelled through the self-venting membrane.

BD PresetTM Blood Gas Syringes

Syringe Recommended Units of heparin* (IU)


Cat. no. Gauge Needle length Connection Tip cap
volume (mL) fill volume (mL) (per syringe/per mL of blood**)

364416 1.0 0.6 30/50 - - Slip tip Conventional

364316 3.0 1.6 80/50 - - BD Luer-LokTM Hemogard style

364413 1.0 0.6 30/50 23 G (0.6 mm) 1” (25 mm) Slip tip Conventional

364415 1.0 0.6 30/50 25 G (0.5 mm) 5/8” (16 mm) Slip tip Conventional

364327 3.0 1.0 80/50 25 G (0.5 mm) 1” (25 mm) BD Luer-LokTM Hemogard style

Syringes supplied in cases of 100

* Spray-dried, calcium-balanced lithium heparin


** At recommended fill volume
49
Arterial blood sampling
BD Critical Care Collection Syringes
BD Critical Care Collection Syringes can be used to collect Further information
blood from a patient’s artery or vein. All syringes contain
Clinical and technical information is available on request.
spray-dried calcium-balanced lithium heparin that enables the
specimen to be analysed for Arterial Blood Gases (ABGs) and
a host of critical care analytes.

BD A-LineTM Blood Gas Syringes


BD A-LineTM syringes are used for blood collection by manual
aspiration and are supplied without needles. They are
designed to be used for arterial or venous blood collection
from an arterial or IV line, and are available in 1mL and 3mL
slip tip and 3mL BD Luer-LokTM syringes.

BD A-LineTM Blood Gas Syringes

Syringe Recommended Units of heparin* (IU)


Cat. no. Gauge Needle length Connection Tip cap
volume (mL) fill volume (mL) (per syringe/per mL of blood**)

364356 1.0 0.6 30/50 - - Slip tip Conventional

364378 3.0 1.6 80/50 - - BD Luer-LokTM Hemogard style

364376 3.0 1.6 80/50 - - Slip tip Conventional

Syringes supplied in cases of 100

50
Urine
collection

Urine collection products products

BD Vacutainer® Urine Collection System


The BD Vacutainer® Urine Collection System is a closed system offering a range
of solutions to meet the needs of each patient according to their age, health and
mobility.

The BD Vacutainer® Urine Collection System can provide solutions for each part of
the process:
• For collection, we have easy-to-use products for the patient and the healthcare
worker
• Our product offerings allow for leak-proof transportation that can be used with
pneumatic tube systems
• Accessioning through a closed system eliminates the need to pour off
androvides the laboratory with a clean sample
• The use of an evacuated closed system ensures a proper urine-to-preservative
ratio
• Our products are designed to be compatible with most commonly used
automated platforms

BD offers a wide range of products for microbiology and urinalysis determinations,


with or without preservatives.

Challenges of using open systems

2x
Up to

70% 78%
bacteria can double of urine cultures reflect of leaked samples are
every 20 minutes false-positive results re-collected, delaying
when a urine specimen and yield no clinically results and increasing
is unpreserved1 relevant information2,3 costs4

Choosing the product that’s right for you to help ensure diagnostic accuracy​

BD Vacutainer® Urine Tubes for Microbiology BD Vacutainer® Tubes for Urinalysis with Additive
Samples can be preserved for up to Samples can be preserved for up to

48 hours
without refrigeration 5
72 hours
without refrigeration 6

BD offers its products in various configurations for urine specimen management:​


Individual components and multiple kit combinations​

1. Bryan C. Microbiology and Immunology On-line. Columbia SC: University of South Carolina School of Medicine, 2017.
Accessed April 17, 2017 at http://www.microbiologybook.org/Infectious%20Disease/Urinary%20Tract%20Infections.htm ​
2. Cronin M. Automated urinalysis technology improves efficiency and patient care. MLO Med Labs Obs. 2008;40(10):30,32.​
3. Simerville JA, Maxted WC, Pahira JJ. Urinalysis: a comprehensive review. Am Fam Physician. 2005;71(6):1153-1162.​
4. Data on file. Becton, Dickinson and Company: Franklin Lakes, NJ; 2010​
5. BD Vacutainer urinalysis preservative plus urine tube Instructions for Use​
6. BD Vacutainer Plus C&S boric acid sodium borate/formate tube Instructions for Use​

51
Urine collection products
BD Vacutainer® Tubes for Urine Specimen

Draw volume
Cat. no. Size (mm) Additive Material Label Cap closure Cap colour Box/Case
(mL)

364980# 8.0 16 x 100 Without additive PET Paper Conventional 100/1,000

364979 10.0 16 x 100 Without additive PET Paper Conventional 100/1,000

364915 11.0 16 x 100 Without additive PET Block BD HemogardTM 100/1,000

BD Vacutainer® Tubes for Urinalysis with Additives

Cat. no. Draw volume (mL) Size (mm) Additive Material Label Cap closure Cap colour Box/case

364992 8.0 16 x 100 Mercury-free stabiliser* PET Paper Conventional 100/1,000

BD Vacutainer® Urine Tubes for Microbiology

Draw volume
Cat. no. Size (mm) Additive Material Label Cap closure Cap colour Box/case
(mL)

364951 4.0 13 x 75 Stabiliser** PET Paper Conventional 100/1,000

BD Vacutainer® Urine Collection Containers and Transfer Units

Alternate
Cat. no. Description Pack/case
Cat. no.

Polypropylene urine cup with


screw closure and integrated
364941 364941 100/200
transfer device, 120-mL capacity,
sterile

Specimen transfer straw,


364940 364940 100/1,000
non-sterile

Luer-LokTM Access Device (male


364902 36490200 198
luer)

The BD Vacutainer® Luer-LokTM Access Device enables transfer Further information


of a urine sample directly from a Foley catheter to the tube. It
Clinical and technical information is available on request.
enables fewer sample collection steps, less manipulation and
reduced risk of contamination1.

#
With conical bottom
* With stabiliser (chlorhexadine, ethyl paraben and sodium propionate)
** Stabiliser for microbiological investigations consisting of boric acid, sodium formate and sodium borate, up to 48-hour
stabilisation of bacterial growth at room temperature.2,3,4
1. Wenger JE. Cultivating quality: reducing rates of catheter-associated urinary tract infection. Am J Nurs. 2010;110(8):40–5.
2. Kouri T, Vuotari L, Pohjavaara S, Laippala P. Preservation of urine for flow cytometric and visual microscopic testing. Clin Chem. 2002;48(6 Pt 1):900–5.
3. BD White Paper VS7097: Evaluation of BD Vacutainer® Urine Culture & Sensitivity PLUS Tube vs. Refrigerated BD Vacutainer® Non-Additive PLUS Tube for Microbiological Testing - Seeded Urine, 2003.
4. BD White Paper VS7099: Evaluation of BD Vacutainer® Urine Culture & Sensitivity PLUS Tube vs. BD Vacutainer® Urine Culture & Sensitivity Glass Tube for Microbiological Testing - Patient Urine, 2003.

52
Urine
collection

Urine collection products products

Various kit combinations are available to meet the demands for your setup:​
BD complete kits​ BD cup kits​ BD transfer straw kits​
A complete system, in addition to A system with urine collection cup Used for a collection cup or bag
the cup and evacuated tubes a and evacuated tubes without a transfer device. These kits
towelette is included for patient contain transfer straws and evacu-
cleansing prior to collection.​ ated tubes.

Urine collection kits

8.0mL, 10.0mL,
8.0mL, 4.0mL,
16x100mm 16x100mm
Sterile Scew-Cap 16x100mm 13x75mm
Plus Plastic Plus Plastic Castile
Collection Plus Plastic Plus Plastic Transfer Packaging
Conical Round Bottom Soap
Cat. no. Cup with Conical C&S Straw Qty (Kits/
Without Without Towelettes
integrated Preservative Preservative Case)
Preservative Preservative
Transfer Device Tube Tube
Tube Tube

364957 ✓ ✓ ✓ ✓ 50

364956 ✓ ✓ ✓ ✓ 50

364954 ✓ ✓ ✓ 50 BD complete kits​

364946 ✓ ✓ 50

364981 ✓ ✓ 50

364989 ✓ ✓ 50 BD cup kits​

364990 ✓ ✓ 50/200

364991 ✓ ✓ 50/200

364943 ✓ ✓ 50/200

✓ ✓
BD transfer straw kits
364953 50/200

53
Additional information
Product quality statement
Product compliance
BD Vacutainer® Blood Collection Tubes and ancillary equipment are (non Annex II) In Vitro Diagnostic Medical Devices.
These comply with the requirements described in the European In Vitro Diagnostic Medical Device Directive 98/79/EC.

BD Precision GlideTM Blood Collection Needles, BD Vacutainer® Blood Collection Sets, BD MicrotainerTM Lancets,
BD SentryTM Lancets, Critical Care Syringes and needles are (class IIa) Medical Devices and as such, comply with the
requirements of the European Medical Device Directive, 93/42/EEC.

All product unit labels ( and most packaging levels) carry the CE mark, signifying conformity to the above Directives.

The UK manufacturing plant, which supplies most European product, is certificated to ISO 13485:2003 and ISO 14001:2004.
As a supplier to the US market the plant is also subject to FDA inspection and therefore holds an FDA establishment registration
certificate. Copies of all these certificates can be provided upon request.

All products are designed and manufactured in accordance with the relevant international and or European standards. This
includes but is not limited to ISO 6710, EN14820 (for blood collection tubes), ISO 6009 (for blood collection needles), EN 980
(for symbols used on product labelling).

The product shelf life is based on data from stability testing and varies from product to product. All expiry dates are clearly
printed on product unit labels, and are valid until the end of the month specified.

Clinical data
Prior to launching a new product BD conducts extensive performance evaluation and data can be provided upon request.

Product sterilisation
All products are sterilised using either gamma irradiation in accordance with ANSI/AAM/ ISO 11137 - 1995 “Sterilisation of
Health Care Products (Requirements for Validation and Routine Control - Radiation Sterilisation)”, Ethylene Oxide (EtO) in
accordance with ISO 11135 - 1994 “Validation and Routine Control of Ethylene Oxide Sterilisation” or Moist Heat Sterilisation
in accordance with EN554 : 1994 “Sterilisation of Medical Devices - Validation and Routine Control of Sterilisation by Moist
Heat”. Microbiological environmental assessment for bio-burden levels is conducted regularly.
All BD Vacutainer® IVD’s and Medical Devices are sterilised to an SAL (Sterility Assurance Level) of 10-6, in accordance with EN
556 : 1995 - Requirement for terminally sterilised devices to be labelled “STERILE”.

BD and Environment
Responsible corporate citizenship is integrally tied to our global business strategy – and to our purpose of “Advancing the World
of Health.

Recognizing that human health and a healthy environment are inseparable, BD is committed to responsible environmental
stewardship in our business conduct. We are dedicated to the design, manufacture and distribution of safe, effective medical
technology products while minimizing environmental impacts. We strive to conserve energy, water, and natural resources and
to minimize the amount of waste from our manufacturing and administrative operations. We promote recycling and resource
recovery in our manufacturing operations. BD collects and reports environmental data on a calendar year basis and a BD
Sustainability report is available on request.

Technical Information Sheets (TIS) for each tube are available on request.
All BD Vacutainer® IVD’s and Medical Devices are sterilised to an SAL (Sterility Assurance Level) of 10-6, in accordance with EN
556 : 1995 - Requirement for terminally sterilised devices to be labelled “STERILE”.

54
F-Flammable

Additional

Additional information
information

Frequently Used Handling & Storage Hazard Misc. Recycle


F-Flammable
Symbols Symbols Symbols Symbols Symbols

ard Misc. Recycle F-Flammable

bols Symbols Symbols The CE mark, signifying compliance with


K2E
F-Flammable

Storage Hazard the European IVD MD Directive, 98/79/EC


Misc. or
Recycle EDTA - dipotassium salt
0086 0050
the MD Directive 93/42/EEC.
ols Symbols Symbols Symbols XXXX

ard Misc. Recycle

K3E
bols Symbols Catalogue
Symbols
or Lot number or batch
EDTA - tripotassium salt
re-order number number
T-Toxic
XXXX
F-Flammabl

Use by, expires


Use once or do
not reuse N2E EDTA - disodium salt
T-Toxic

XXXX

Sterile fluid path.


9NC
XXXX
Sterilised by
ge Hazard Misc.
moist heat Recycle Sterilised by Trisodium citrate 9:1
Symbols Symbols Symbols irradiation T-Toxic
F-Flammable

Sterilised by
irradiation
Sterilised by
Ethylene Oxide gas 4NC Trisodium citrate 4:1
T-Toxic

Keep away from


sunlight (may show
temperature range)
XXXX
Protect from any
light source FX Fluoride/Oxalate
F-Flammable F-Flammable

mable

Frequently
Fragile
Symbols
Used Handling & Storage
Symbols
Storage
temperature
Hazard
range
Symbols FE
Misc. Fluoride/EDTA
Symbols
Recycle
Symbols

mable
This way up Recycle FH
T-Toxic
Fluoride/Heparin

age Hazard Misc. Recycle


Date of
Symbols manufacture
Symbols Symbols Serial number LH Lithium heparin XXXX

“Caution” - consult

NH
T-Toxic
Frequently Used Handling
instructions for use for & Storage Hazard
Keep dry Misc. Recycle
Sodium heparin
important cautionary
Symbols information Symbols
F-Flammable Symbols Symbols Symbols T-Toxic

andling & Storage Hazard Misc. Recycle


In vitro diagnostic
Z
xic XXXX
T-Toxic

Symbols Manufacturer
Symbols
F-Flammable Symbols medicalSymbols None (no additive)
device

Authorised
Consult instructions The abbreviationsXXXX
used in this catalogue have the follow-
xic
representative in ing meanings:
for use
the EU community PU = Packaging unit
G = Gauge
RT = Room temperature
XXXX RCF = Relative centrifugal force
g = g-number
IVD = in vitro diagnostics

55
T-Toxic
F-Flammable
Disclaimer: The information provided herein is not meant to be used, nor should it be used, to diagnose or treat any medical condition. All content, including text,
graphics, images and information etc., Contained in or available through this literature is for general information purposes only. For diagnosis or treatment of any
medical condition, please consult your physician/doctor. Becton Dickinson India Private Limited and or its affiliates and its employees are not liable for any
damages/claims to any person in any manner whatsoever.

BD Life Sciences – Specimen Management


Becton Dickinson India Private Limited
5th & 6th Floor, Signature Tower -B,
South City - 1, Gurgaon-122001
Haryana, India
Tel: 91-124-4124300, Fax: 91-124-2383224/5/6

bd.com
©2021 BD. BD, the BD Logo and Vacutainer are trademarks of
Becton, Dickinson and Company. Printed in India
56

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