▪ Endocrine, CNS, Bone Quiz

‫ ۔‬G1:
1. Sequestrum is a:
A. Newly formed bone.
B. Dead bone. ✔️
C. Dead soft tissue.
D. Granulation tissue.

2. Grave's disease is:

A. Degenerative disease.
B. Autoimmune. ✔️

3. Alzheimer's disease is:

A. Demyelinating disease.
B.
C. Degenerating disease. ✔️

4. It is necessary to detect invasion in one of the thyroid tumor:

A. Papillary carcinoma.
B. Follicular carcinoma. ✔️
C. Medullary carcinoma.
D. Anaplastic carcinoma.

5. Rosette appearance is found in:

A. Oligodendroma.
B. Astrocytoma.
C. Ependymoma. ✔️

6. Osteoma is all the following except:

A. Painful but does not respond to aspirin. ✔️

2
T/F:
1. Osteophyte occurs in osteoarthritis. ✔️
2. Ewing sarcoma arises from osteoblast. ❌
3. Pheochromocytoma is associated with catecholamine releasing. ✔️

4. Medullary carcinoma of thyroid is not derived from parafollicular cells. ❌

5. Palisading arrangement appear in Antoni A of schwannoma. ✔️
6. Acute suppurative otitis media may cause meningitis. ❌

‫ ۔‬G2:
1. Mosaic histological pattern is feature of:
A. Paget's disease. ✔️
B. Osteoporosis.
C. Chronic osteoarthritis.
D. Chronic osteomyelitis.

2. The following is not cause of osteoporosis:

A. Old age.
B. Hyperparathyroidism.
C. Malnutrition.
D. Chronic osteomyelitis. ✔️

3. The following is not feature of meningiomas:

A. Usually occurs in children. ✔️
B. Has whorly appearance.
C. CHCH by psammoma bodies.
D. May related to hormone.

3
4. GBM shows:
A. Rosenthal fibre.
B. Rossette formation.
C. Vascular proliferation. ✔️
D. None of the above.

5. Simple goiter is due to:

A. Diet iodine deficiency. ✔️
B. Autoimmune reaction.
C. Thyroiditis.
D. All of the above.

6. The most important criteria of malignant pheochromocytoma is:

A. Cytological atypia.
B. Necrosis.
C. Vascular proliferation.
D. None of the above. ✔️

T/F:
1. Rheumatoid arthritis is a cause of amyloidosis. ✔️
2. The big toe is the commonest site of urate microcrystal deposition. ✔️
3. GBM İs a benign astrocytic tumor. ✔️

4. Active multiple sclerotic plaque doesn't show gliosis. ❌

5. Riedel's thyroiditis is a granulomatous lesion. ❌

6. Cytological features is important in diagnosis of papillary carcinoma. ✔️

‫ ۔‬G3:
1. Osteoid osteoma occurs in:
A. Cortex. ✔️
B. Medullary cavity.
C. Periosteum.

4
2. The common tumor in children:
A. Ependymoma.
B. Oligodendroglioma.
C. Schwannoma.
D. None of the above. ✔️

3. Osteomalacia occurs in:

A. Pelvis. ✔️
B. Spine.
C. Metatarsal.

4. What is type of tumor secrete catecholamine:

A. Pheochromocytoma. ✔️
B. Neuroblastoma.

5. Goiter toxic is caused by:

A. Autoimmune.
B. Thyroiditis.
C. Iodine Deficiency.
D. None of the above. ✔️

6. Astrocytoma shows:
A. Rosenthal fibres. ✔️
B. Rosettes appearance.

T/F:
1. Pigmented villonodular synovitis Isn't locally malignant tumor. ❌
2. Synovial sarcoma is always biphasic tumor. ❌

3. Anaplastic tumor secrete amyloid. ❌

4. Neurofibrillary is characterized features of Alzheimer disease. ✔️

5. Clear cell in grade 3 meningioma. ❌

5
▪ Female, Male, Breast
‫ ۔‬G1:
1. Fertilization of normal ovum by 2 sperms result in:
A. Choriocarcinoma.
B. Partial mole. ✔️
C. Invasive mole.
D. Complete mole.

2. Adenoacanthoma is:
A. Endometroid carcinoma with benign squamous epithelium. ✔️
B. Endometroid carcinoma with malignant squamous epithelium.
C. Not endometroid carcinoma.
D. None of the above.

3. The most important premalignant lesion in endometrial carcinoma is:

A. Endometrial polyps.
B. Endometriosis.
C. Endometrial hyperplasia. ✔️
D. Endometritis.

4. The most common tumor in old age is:

A. Seminoma. ✔️
B. Yolk sac.
C. Teratoma.
D. Embryonal carcinoma.

5. 35 years female come to the clinic with eczematous lesion red not
palpable mass in the areola of breast histological diagnosis show large
cell vacuolated at dermoepidermal junction the most diagnosis is:
A. Paget disease. ✔️
B. Intraductal carcinoma.
C. Inflammatory carcinoma.

6
6. Gynaecomastia is due to:
A. Increase progesterone.
B. Increase estrogen. ✔️
C. Decrease estrogen.
D. None of the above.

7. Which of the following tumor is usually benign tumor:

A. Seminoma.
B. Yolk sac.
C. Sertoli ledge cell tumor. ✔️
D. Embryonal carcinoma.

8. Which of the following tumor may show lung metastasis:

A. endometroid carcinoma. ✔️
B. Invasive mole.
C. Teratoma.
D. Seminoma.

T/F:
1. Papillary Serous carcinoma is benign tumor. ❌
2. Corpus luteal cyst associated with increased progesterone level. ✔️

3. HPV may cause condyloma acuminatum. ✔️

4. Indian file appearance isn't characteristics of tubular carcinoma. ✔️
5. All testicular germ cell tumor are benign tumor. ❌

6. Choriocarcinoma associated with low level of HCG. ❌

7. Grading ILCs depends on the mitotic activity. ❌
8. the prostatic hyperplasia take the periphery of the gland. ❌

7
‫ ۔‬G2:
1. Vulvular Paget's disease is a:
A. Carcinoma in situ. ✔️
B. Invasive carcinoma.
C. Inflammatory lesion.
D. Tumor- like lesion.

2. Adenomyosis is:
A. Type of leiomyoma.
B. Type of endometriosis. ✔️
C. Tumor like lesion.
D. None of the above.

3. Schiller Duvall bodies are CHCH of:

A. Teratoma.
B. Embryonal carcinoma.
C. Granulosa cell tumor.
D. Yolk sac tumor. ✔️

4. Choriocarcinoma consists of:

A. Malignant fibrous stroma.
B. Malignant Synocytotrophoblasts. ✔️
C. Chorionic villi.
D. All of the above.

5. A 19-year-old lady, she is on breast feeding for a month, but notes

that her left breast has gradually become swollen and painful to touch
over the past week. On physical examination her temperature is 38.2C.
Which of the following is the most likely diagnosis?
A. Acute mastitis. ✔️
B. Fibrocystic disease.
C. Fat necrosis.

6. Fibrocystic disease has all except:

A. Stromal fibrosis.
B. Cystic changes.
C. Squamous metaplasia. ✔️
D. Lymphocyte infiltration.

8
7. BPH is CHCH by all except:
A. Occurs in old age.
B. Firm and nodular.
C. Affect peripheral zone. ✔️
D. Not premalignant lesion.

8. The following conditions is the main risk factor of Neoplasm:

A. Chronic orchitis.
B. Undesending testis. ✔️
C. BPH.
D. Testicular atrophy.

T/F:
1. Psudomyxoma pertoneii is seen in case of serous endometrioid carcinoma. ❌
2. Subserosal Leiomyoma is the main cause of infertility. ❌

3. Adenoacanthoma is a benign uterine tumor. ✔️

4. Corpus lutum cyst is associated with increase estrogen level. ❌
5. Indian file pattern is a feature of tubular carcinoma. ❌

6. Fibrocystic lesions is a mobile breast mass. ❌

7. The main site of Prostate carcinoma metastasis is brain. ❌

8. Epididymitis is the main cause of seminoma. ❌

‫ ۔‬G3:
1. Condyloma accuminatum is not characterised by:
A. It is sexually transmitted.
B. It is induced by Epstein Barr virus. ✔️
C. It consists of proliferating squamous epithelium.
D. It is characterised by perinuclear vacuoliation.
E. It's precancerous.

9
2. Most common endometrial cancer is:
A. Endometrioid. ✔️
B. Adenoacanthoma.
C. Serous.

3. Grading of cervical intraepithelial neoplasia (CIN) depends on:

A. Thickness of the epithelium showing loss of maturation. ✔️
B. Nuclear-cytoplasmic ratio.
C. Number of the mitotic figures.
D. None of the above.

4. Fertilization of a dead egg with 2 sperm is:

A. Abortion.
B. Partial mole.
C. Complete mole. ✔️
D. Choriocarcinoma.

5. Which of the following is not malignant:

A. Seminoma.
B. Immature teratoma.
C. Yolk sac tumor.
D. None of the above. ✔️

6. The most important prognostic factor for Prostate cancer is:

A. Histological grade.
B. Tumor size.
C. PSA level. ✔️
D. All of the above.

7. A 45 women comes to the hospital with a lump in the left upper

quadrant of her left breast. Biopsy was done and revealed a benign
tumor. What is the most important ChCh to indicate malignancy:
A. Atypical hyperplasia. ✔️
B. Adenosis.
C. Apocrine metaplasia.

10
8. The most Important prognostic factor in beast carcinoma is:
A. The Histological tumor.
B. The tumor site.
C. axillary lymph node status. ✔️
D. All of the above

T/F:
1. Invasive mole may send distal metastasis. ✔️
2. Schiller duval bodies are chch of sertoli cell cancer. ❌
3. Phylloide carcinoma is of mesenchymal origin only. ❌
4. Endometrial hyperplasia is never metastasis. ✔️
5. Peua 'd orange of breast is due to size of the tumor. ❌

6. In Embryonal carcinoma AFP is elevated. ❌

7. presenceofbilateralovarian Signet ring carcinoma is always metastasis. ✔️
8. All germ cell tumors are malignant except immature teratoma. ❌

11