Name:
THE CELL CYCLE AND CANCER
Video Handout
This handout accompanies the The Cell Cycle (and cancer) video by the Amoeba Sisters on
YouTube. Complete the Before the Show section first. Then, try to guess the answers to the
Showtime questions before starting the video.
Full URL: https://www.youtube.com/watch?v=QVCjdNxJreE&t=357s Tiny URL: https://tinyurl.com/ycxnj88c
BEFORE THE SHOW (answer before you start video)
What types of activities do you think the cells in your body are performing right now? Brainstorm and list any activities
or processes you believe your cells are currently doing.
SHOWTIME QUESTIONS (answer while viewing the video)
1. How does a multicellular organism grow? 9. What occurs in the S phase of interphase?
a. existing cells grow in size a. the cell grows
b. existing cells divide and reproduce b. the cell divides
c. new cells replace existing cells c. the cell replicates its DNA
2. Which process allows your body to create more cells? 10. What does the cell check in the G1 checkpoint?
a. meiosis a. if the cell is growing and if its DNA is
b. binary fission damaged
c. mitosis b. if the DNA is replicated correctly
c. if the chromosomes are replicated correctly
3. What is cancer?
a. uncontrolled cell division 11. In which mitotic phase does the cell check to make
b. uncontrolled cytokinesis sure that chromosomes are lined up correctly?
c. controlled cell division a. prophase
b. metaphase
4. Which of the following is NOT true of cancer cells? c. anaphase
a. they may overcommunicate with healthy cells
b. they may not be able to carry out normal cell 12. What happens if a cell doesn’t meet the
functions requirements of a checkpoint and can’t be fixed?
c. they may develop into a tumor a. it mutates
d. they can take nutrients away from healthy cells b. it is replaced with a healthy cell
c. it undergoes apoptosis
5. In which phase of the cell cycle are cells growing,
replicating DNA, and carrying out cell functions? 13. What proteins rise and fall during the cell cycle to
a. interphase determine if the cell should move on to the next
b. mitosis phase?
c. meiosis a. mitosis
b. cyclin
6. In which phase are cells actively dividing? c. cytocyclin
a. interphase
b. mitosis 14. Which type of regulators are involved in apoptosis?
c. meiosis a. positive regulators
b. negative regulators
7. Cytokinesis is the splitting of the cytoplasm. c. CdK regulators
a. true
b. false 15. Which types of cells are in the G0 resting phase
and typically do not replicate?
8. Where do cells spend most of their time? a. heart and liver cells
a. mitosis b. red and white blood cells
b. cytokinesis c. neurons in the brain and spinal cord
c. interphase © SCIENCE IS REAL
AFTER PARTY QUESTIONS (answer after you finish video) Name:
A. Label the name of each part of the cell cycle on the diagram below. Then, fill in the table to summarize what occurs
at each phase.
Phase Summary
G1
S Phase
G2
M Phase
Cytokinesis
B. Complete the crossword puzzle.
Across 1
1. a negative regulator that is involved in
initiating apoptosis
4. the splitting of cytoplasm
6. uncontrolled cell growth
7. chromosome alignment is checked during 2
this stage of mitosis
10. type of regulator that allows for moving
forward in the cell cycle 3 4 5
11. the process of cell division
Down 6 7
1. regulators are made up of this
type of biomolecule
2. self-destruction of a cell
8
3. this is replicated during the S
phase
4. along the cell cycle are _____
that check if the cell is growing
and replicating its DNA correctly
9
5. phase where cells spend most of
their time 10
6. this molecule rises and falls in the
cell cycle to determine when the 11
cell should move on to the next
cell cycle phase
8. a type of regulator that may stop
the cell cycle
9. a clump or collection of cancer
cells
EXTENSION
Research one type of cancer treatment (chemotherapy, radiation therapy, or immunotherapy) and summarize how
this treatment works to destroy cancer cells.
© SCIENCE IS REAL
