Professional Documents
Culture Documents
(27217 - Histologi) Sistem Respirasi - Dr. Susianti
(27217 - Histologi) Sistem Respirasi - Dr. Susianti
Sc
GENERAL FEATURES OF THE
RESPIRATORY SYSTEM
Lobar bronchi
Primary bronchus give rise:
Right primary bronchus: 3 secondary bronchi
Left primary bronchus: 2 secondary bronchi
Segmental bronchi
Supplies one bronchopulmonary segment
(pulmonary lobule)
Histologic appearance is identical to that
of secondary bronchi
Branch several times to form smaller
branches
Tertiary (Segmental) Bronchus
D. BRONCHIOLES
Branches of the smallest bronchi
Largest bronchioles differ from the smallest
bronchi: absence of the cartilage and glands in
their walls
Large bronchioles:typical respiratory epithelium
Further: epithelial height and complexity
decrease to simple ciliated columnar or
cuboidal
Each bronchiole gives rise to 5-7 terminal
bronchiole
Bronchiolus
Vein
Alveolar walls
E. TERMINAL BRONCHIOLES
The smallest components of the conducting
portion
Lined by ciliated cuboidal or columnar
epithelium, have few or no goblet cells
Lining also: dome-shaped cilia-free Clara
cells
Each terminal bronchiole branches to form
2 or more respiratory bronchioles
F. RESPIRATORY BRONCHIOLES
2. Type II cells
Called type II alveolar cells, type II pneumocytes,
great alveolar cells, alveolar septal cells
Are roughly cuboidal with round nuclei
Large (0.2 m) membrane-limited lamellar bodies
Secretes pilmonary surfactant
3. Alveolar macrophages
Called dust cells
Mononuclear phagocyte system on the surface of
the alveolar septa and in the intersitium
Alveoli
Three-dimensional schematic diagram of pulmonary alveoli showing the interalveolar
septum and its structure. Observe the capillaries, connective tissue, and macrophages.
These can also be seen in or passing into the alveolar lumens. Alveolar pores are
numerous. Type II cells are identified by their abundant apical microvilli. The alveoli
are lined by a continuous epithelial layer of Type I cells.
C. PULMONARY SURFACTANT
Continously synthesized and secreted by
type II alveolar cells onto the alveolar
surface
2 Function:
Reduce surface tension in the alveoli
Have some bactericidal effects
2 layer:
Aqueous basal layer (hypophase)
Monomolecular fill of phospholipid (dipalmitoyl
lecithin)
PULMONARY CIRCULATION
A. BLOOD SUPPLY
1. Functional circulation
a. Pulmonary arteries
b. Pulmonary veins
2. Systemic circulation
a. Bronchial arteries
b. Bronchial veins
B. LYMPHATIC DRAINAGE