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  • Farmakoterapi Kasus 1

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    Trisna Burhanudin
    6 views11 pages
    This document discusses angina pectoris, or chest pain. It covers the etiology, epidemiology, pathophysiology, and risk factors of the condition. The pathophysiology section explains that angina occurs due to insufficient oxygen supply to heart muscle cells, which can result from stiffening and narrowing of coronary arteries. When heart muscle cells do not receive enough oxygen, they switch to less efficient energy production through glycolysis rather than oxidative phosphorylation, producing lactic acid and lowering pH in heart muscle tissue. This causes the smooth muscle in coronary arteries to spasm, further restricting blood flow and exacerbating the oxygen shortage. The document then lists risk factors for angina on the following pages.

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    Study case farmakoterapi

    Original Title

    FARMAKOTERAPI KASUS 1

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    This document discusses angina pectoris, or chest pain. It covers the etiology, epidemiology, pathophysiology, and risk factors of the condition. The pathophysiology section explains that angina occurs due to insufficient oxygen supply to heart muscle cells, which can result from stiffening and narrowing of coronary arteries. When heart muscle cells do not receive enough oxygen, they switch to less efficient energy production through glycolysis rather than oxidative phosphorylation, producing lactic acid and lowering pH in heart muscle tissue. This causes the smooth muscle in coronary arteries to spasm, further restricting blood flow and exacerbating the oxygen shortage. The document then lists risk factors for angina on the following pages.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    6 views11 pages

    Farmakoterapi Kasus 1

    Uploaded by

    Trisna Burhanudin
    This document discusses angina pectoris, or chest pain. It covers the etiology, epidemiology, pathophysiology, and risk factors of the condition. The pathophysiology section explains that angina occurs due to insufficient oxygen supply to heart muscle cells, which can result from stiffening and narrowing of coronary arteries. When heart muscle cells do not receive enough oxygen, they switch to less efficient energy production through glycolysis rather than oxidative phosphorylation, producing lactic acid and lowering pH in heart muscle tissue. This causes the smooth muscle in coronary arteries to spasm, further restricting blood flow and exacerbating the oxygen shortage. The document then lists risk factors for angina on the following pages.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 11

    FARMAKOTERAPI

    KASUS 1

    KELOMPOK 2
    STUDY CASE

    Let’s Begin Now


    ANGINA PEKTORIS
    ANGINA PEKTORIS
    ETIOLOGI
    EPIDEMIOLOGI
    PATOFISIOLOGI

    Kekurangan supply Oksigen


    Kekakuan dan Penyempitan arteri koroner (sel-sel miokardium)
    Cedera endotel

    Hilangnya fungsi nitrat Oksida

    Pada metabolisme glikogen

    Menghasilkan asam laktat yang


    menurunkan ph miokardium

    otot polos berkontraksi dan timbul spasmus


    koroner yang memperberat penyempitan lumen

    keutuhan energi sel-sel jantung berkurang,


    maka suplai oksigen menjadi adekuat dan
    sel-sel otot kembali fosforilasi oksidatif untuk
    nyeri
    membentuk energi
    FAKTOR RESIKO

    8
    FAKTOR RESIKO

    9
    FAKTOR RESIKO

    10
    THANK YOU!
    Any Questions?

    Jun Akizaki – The Power of PowerPoint


    Used Font: Crimson Text

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