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Necrotizing Enterocolitis: Department of Childhealth, School of Medicine, University of North Sumatera Medan
Necrotizing Enterocolitis: Department of Childhealth, School of Medicine, University of North Sumatera Medan
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gestational age
NECROTIZING ENTEROCOLITIS
An Acute Intestinal Necrosis Syndrome Resulting From
Complex Interaction :
= Gut Ischemia
= Poor Mucosal Integrity
= Microbial Infection
= Enteral Nutrition
MUCOSAL INJURY
INTESTINAL PERFORATION
Immaturity Ischaemia
Milk feeds
Loss of barrier function
Mucosal disruption
Mucus
enterocyt
Goblet cell
nucleus
ENTERAL FEEDING
B. Surgical
1. Perforation
2.Fixed dilated loop on serial x-ray
3.Abdominal wall cellulitis
4.Progressive deterioration despite maximal medical
support
Medical
1.Preventing futher injury
a. Cessation of feeding
b. Decompression
c. IntraVenous Fluid Drip ( IVFD )
2.Supportive
a. Respiration status
b. Coagulation profile
c. Electrolyte and Acid base balance
d. Antibiotics
PREVENTION
1. EXCLUSIVELY BREAST-FED
2. MINIMAL ENTERAL FEEDS FOLLOWED BY
JUDICIOUS VOLUME ADVANCEMENT
3. PROBIOTIC