Biocompatible Microcrystalline Cellulose Particles From Cotton

Wool and Magnetization Via A Simple In Situ Copresipitation

Method

MEHNAZ RASHID, MOHAMMAD ABDUL GAFUR, MOSTAFA KAIYUM

SHARAFAT, HIDETO MINAMI, MOHD ABDUL JALIL MIAH, HASAN AHMAD.

Anggun S.W.A
NIM. 1508103010055

Chemistry Department, Faculty of Science Syiah Kuala University

 Introduction

Cellulose is a naturally occurring most

abundant renewable polymer on earth.

Cellulose is a polysaccharide
carbohydrate consisting of β -d-
glucopyranose units joined by β-1,4
glycosidic linkages in a linear
arrangement along with varied amounts
of hemicelluloses and lignin.

Chemistry Department, Faculty of Science Syiah Kuala University

MCC powder were prepared from the bleached pulp of cotton
wool hidrolyzed by sulfuric acid.

Can be useful as a green product for catalysis, designing drug

delivery systems and adsorbents for water and biomolecule
purification

Magneto graphic printing, electromagnetic shielding,

transparent films for magneto-optical applications, functional
cellulose composites, magnetic filters and a magnetic aerogels

Chemistry Department, Faculty of Science Syiah Kuala University

 The Objective of this Investigation

To synthesize microcrystalline cellulose

(MCC) nanocomposite particles with
superparamagnetic properties.

Chemistry Department, Faculty of Science Syiah Kuala University

 The Experimental

Preparation scheme of MCC/Fe3O4 nanocomposite particles from cotton wool

Chemistry Department, Faculty of Science Syiah Kuala University

 Results and Discussion

The FTIR spectra raw of cotton wool and MCC particles produced by
hydrolysis with sulfuric acid of variable strength with a) MCC particles without
hydrolysis; b) 40%; c) 50%; d) 55% and e) 70% sulfuric acid concentration

Chemistry Department, Faculty of Science Syiah Kuala University

 The XRD patterns of bleached cotton wool with a) MCC powder
without hydrolysis; b) 40% and c) 50% hydrolized by sulfuric acid
shows the crystallinity index of MCC.

Chemistry Department, Faculty of Science Syiah Kuala University

 MCC Particles
with Sulfuric Acid
Concentration

a. 40%
b. 50%
c. 55%
d. 70%

The Average
Length of MCC
Particles

a. 70 μm
b. 52 μm
c. 43 μm
d. 37 μm

The effect of sulfuric acid strength on the size and morphology of MCC particles

Chemistry Department, Faculty of Science Syiah Kuala University

 The FTIR spectra of MCC/Fe3O4 nanocomposite particles prepared
with variable Fe3O4 contents a) 1/0.1; b) 1/0.2 and c) 1/0.3

Chemistry Department, Faculty of Science Syiah Kuala University

 MCC to Fe3O4
a) 1/0.1
b) 1/0.2
c) 1/0.3

The surface morphology of MCC/Fe3O4 nanocomposite particles

prepared with variable iron oxide contents was evaluated by SEM
micrographs
Chemistry Department, Faculty of Science Syiah Kuala University
The XRD patterns of MCC/Fe3O4 nanocomposite particles prepared with
variable iron oxide with a)1/0.1; b) 1/0.2 and c) 1/0.3

Chemistry Department, Faculty of Science Syiah Kuala University

The XPS survey spectra used to confirm the surface composition of
MCC/Fe3O4 nanocomposite particles were prepared with variable iron
oxide with a) MCC/Fe3O4 nanocomposite particles; MCC to Fe3O4 b)
1/0.1; c) 1/0.2 and d) 1/0.3

Show the presence of Fe2p signal and the signal due to S2p derived from
FeSO4 is not visible indicating the absence of any impurity from the
starting materials in magnetically modified MCC particles.

Chemistry Department, Faculty of Science Syiah Kuala University

 TGA analysis of MCC particles hydrolyzed by 70% sulfuric acid shows a
minor initial mass loss, which is related to the evaporation of adsorbed
water.

a. MCC powder without b. Fe3O4 MCC to Fe3O4

hydrolysis nanoparticles c) 1/0.1; d) 1/0.2; e) 1/0.3

Chemistry Department, Faculty of Science Syiah Kuala University

 The accumulation of such nanocomposite particles towards the external magnetic
field
Fig. a. Shows the MCC after hydrolized by sulfuric acid.
Fig. b and c. Shows the MCC/Fe3O4 nanocomposite emulsion and accumulation of
dried MCC/Fe3O4 nanocomposite particles under the influence of external
magnetic field prepared with variable MCC to Fe3O4 rations.
Fig. d, e and f. Shows the ratios of MCC composite d. (1/0,1); e. (1/0,2); f (1/0,3).

Chemistry Department, Faculty of Science Syiah Kuala University

 The magnetic properties of magnetically separated MCC/Fe3O4
nanocomposite particles were performed by VSM analysis and the
hysteresis loop of nanocomposite particles prepared with different MCC
to Fe3O4 ratios.

Chemistry Department, Faculty of Science Syiah Kuala University

 The Conclusion is...
Biocompatible The value of
MCC/Fe3O4 nanocomposite particles
cotton wool derived crystallinity index
prepared from 70% acid possessed
MCC particles were reached maximum
good paramagnetic property and
prepared by when 50% sulfuric
could be accumulated both in
hydrolysis with acid
emulsion and dried states by
variable percentages concentrations.
external magnetic field.
of sulfuric acid.

The MCC/Fe3O4
Surface morphology nanocomposite However, to avoid the
confirmed the particles possessed by production of free the
distribution of Fe3O4 maximum saturation best MCC to iron oxide
nanoparticles along magnetization when weight ratio was found
the MCC fiber MCC to iron oxide to be 1/0.1.
matrix. weight ratio was set at
1/0.2.

Chemistry Department, Faculty of Science Syiah Kuala University