Etiology and Risk Factor of Deficiency

and Aplastic Anemia

Etiology:
 Increased Iron requirements &/or hematopoiesis
1. Growth
2. Pregnancy & lactation
 Increased Iron loss/Blood loss
Gastrointestinal tract, Genitourinary tract, respiratory tract,
blood donation, phlebotomy as treatment for polychythemia
vera
 Decreased Iron intake or absorption
1. Dietary insufficiency of bioavailable Iron
2. Impaired absorption of Iron: intestinal malabsorption, gastric
surgery,Iron−refractory Iron deficiency anemia
3. Acute or chronic inflammtion
ETIOLOGY
Aplastic
anemia

Primary Secondary

•Radiations
Congenital •Drugs
•Chemicals
•Viruses
Immunological •Pregnancy
mediated
acquired form •PNH
 Risk Factor
• A diet lacking in certain vitamins
• Intestinal disorder
• Menstruation
• Pregnancy
• Chronic Condition
• Family history
• Other factor (ex. drugs)
• Age
• Severe fatigue
• Heart problems