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Departement of Pediatric,
Faculty of Medical, Diponegoro University
Dr. Kariadi Hospital, Semarang
BACKGROUND
There was still a few study about risk factors of neonatal severe
acidosis
Ricki F, et al. Influence of Acidosis, Hypoxemia, and Hypotension on Neurodevelopmental Outcome in Very Low
Birth Weight Infants. Pediatrics 1995;95;238
OBJECTIVES
To determine risk factors for neonatal death of
severe acidosis in Dr. Kariadi General Hospital
METHODS
Case control study
Data collected from medical records in
NICU
Dr. Kariadi General Hospital
January - December 2015
Divided into 2 groups
• Case group severe acidosis (pH<7,0)
• Control group mild-moderate acidosis
(pH 7,0-7,2)
Analyzed by using logistic regression
analysis
• Risk factors studied :
• Maternal age
• Method of Delivery
• Gestational Age
• History of PROM
• History of Eclampsia/PE
Variables OR 95% CI P
Maternal Age 2,46 0,18 – 33,63 0,50
Low Birthweight 5,16 1,02 – 26,07 0,047
Congenital Deformity 111,04 1,734 – 109,54 0,026
Surgical Procedure 8,06 0,35 – 183,91 0,19
•De Franco S, Esposito S, Rossaro D, Bona G, Ferrero F. Risk factors in newborns with severe acidosis at birth.
Panminerva Med 2007;49:17–9
•Goldaber KB, Gilstrap LC III, Leveno KJ. Pathologic fetal acidemia. Obstet Gynecol. 1991; 78: 1103-
CONCLUSION