Ferrous Fumarate

Antimony gluconate
IUPAC name (E)-But-2-enedioate; iron(2+)
Ferrous fumarate is the iron(II) salt of fumaric acid, occurring as
a reddish-orange powder.
It is used to supplement iron intake.
Pure ferrous fumarate has an iron content of 32.87%,
therefore one tablet of 100 mg iron fumarate will contain 32.86 mg of
iron
Ferrous Fumarate (Iron II Sulphate)

Properties
Chemical formula C4H2FeO4
Molar mass 169.90 g/mol
Appearance reddish-brown powder
Odor odorless
3
Density 2.435 g/cm (20 °C)
Melting point 280 °C (536 °F; 553 K)
Solubility in water hardly soluble
Solubility in alcohol Slightly soluble
Preparation
The synthesis of iron(II) fumarate is based on the fumaric acid
conversion into disodium fumarate by neutralization (1:2). Disodium
fumarate, as intermediate mater, reacts with iron(II) sulfate (1:1),
yielding iron(II) fumarate, brick-red precipitate with over 98 % purity.
The reaction was performed in nitrogen atmosphere at
90 °C during 30 minutes providing an inert atmosphere
required to prevent oxidation of ferrous ions to ferric.
USES
• Pernicious anemia
• Iron deficiency anemia
• Iron deficiency
• When patient can’t tolerate other iron preparation.
Antimony gluconate