Overview of Immunity • Immunity – a “condition of” (-ity) “not serving” (immun) disease • Lymphatic-immune system – “organ system that functions together to provide a broad prophylaxis or “guarding against” disease” (Layman, 2007, p. 92) • Acts as blood filtering system for: • Bacteremia – a “blood condition of” (-emia) invading “bacteria” (bacter) • Cancer cells • Tumor cells Lymphatic System Henry Vandyke Carter [Public domain], via Wikimedia Commons
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Overview of Immunity, cont. • Lymphatic circulation occurs within lymphatic vessels • “Shadow” the way blood circulates within blood vessels • Capillaries – tiny, narrow vessels that “have the nature of” (-ary) “tiny hairs” (capill) • Blood pressure (BP) – pushes blood through blood capillaries • Also pushes outward, causing a net filtration process • Filtration product then enters lymphatic capillaries and becomes lymph (resembles “clear spring water”) • Lymph then flows into larger lymphatic veins, then into lymphatic ducts. • Finally, the cleansed fluid returns back to the blood veins (Layman, 2007, p. 92-94)
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Immune Response • Antigen – a foreign protein that surrounds the outer membrane of an invading cell • Antigen – “produced” (-gen) “against” (anti-) • Certain types of lymphocytes (lymph cells) act as scouts to detect antigens • Lymphocytes then send a message to a second type of lymphocyte, which, transforms itself into a plasma cell • Plasma cells – main source of antibodies • Antibodies – types of proteins that act “against” (anti-) foreign invaders • Antigen-antibody reaction – Antibodies chemically attach and bind to antigens on bacterial cells
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Immune Response, cont. • Lysis – chemical “breakdown” (lys) that bacteria undergoes after the antigen-antibody reaction • Phagocytosis – a “process of” (-osis) “cell” (cyt) “eating” (phag) • Wandering macrophage – a “large” (macr) “eater” (phag) that is “present” (-e) • Cells that wander through lymphatic system and engulf foreign invaders • Clinical health – lack of disease achieved by immune response (Layman, 2007, p. 94-96)
Diagnosis • Diagnosis – “a condition of” (-is) “knowledge” (gnos) “through” (dia-) • E.g., acute coryza • Acute – “presence of” (-e) something “sudden” (acut) • Coryza – Greek for “runny nose”; also called rhinitis • Symptoms – “happenings” • Examples of other cold symptoms: • Edema (“swelling”) of nasal passages • Congestion – a “process of” (-ion) one’s nasal passages becoming “stuffed up” (congest)
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Diagnosis, cont. • Clinical signs – “marks” of illness or disease detected by a doctor or examiner • E.g., Febrile – “having” (-ile) a moderate “fever” (febr) • Syndrome – “together” (syn); from Greek, “running together” • Clinical syndrome – a group of clinical symptoms and signs that “run together” in a particular patient at the same time • Prodrome – “a running” (drome) “before” (pro-) • E.g., malaise – a feeling of body weakness or “discomfort” • Prognosis – “a condition of” (-is) “knowledge” (gnos) “before” (pro-) (Layman, 2007, p. 98-100)
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Diagnostic Tools and Techniques • Techniques: • Palpation – “a process of” (-ion) “touching” (palpat) • E.g., use of abdominal palpation to diagnose an enlarged liver • Percussion – “a process of” (-ion) “striking” (percuss) • Tapping a body surface with the fingertips in order to evaluate size, borders, and consistency of underlying internal organs • Auscultation – “a process of (-ion) “listening” (auscult) • In ancient times, physicians placed an ear directly on the patient’s body surface • Now, stethoscopes are used (Layman, 2007, p. 100-101)
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The Stethoscope • René Laennec – French physician (1781-1826) who invented the stethoscope • Stethoscope – “an instrument to examine” (scope) the sounds of the “chest” (steth) • Hollow, wooden cylinder over which Laennec placed his ears • Produced amplification – “enlargement (boosting)” of chest sounds (Layman, 2007, p. 101)
Four Laennec Stethoscopes
By Wellcome Images licensed under [CC BY 4.0], via Wikimedia Commons.
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Ultrasound • Ultrasonics – science “pertaining to” (-ic) vibrations that are far “beyond” (-ultra) the range of audible “sound” (son) • Ultrasound technology – developed by Ian Donald, a British physician • Donald altered ultrasonic technology used during World War II to detect enemy submarines • Medical ultrasonography – the “process of recording” (-graphy) extremely high-frequency sound waves reflected off internal body structures
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Ultrasound, cont. • Sonogram – visible tracing resulting from this process • E.g., fetal sonograms • Fetus – unborn “offspring” (fet) during later stages of pregnancy • Prenatal problems – those that occur “before” (pre-) “birth” (nat) (Layman, 2007, p. 101-103)
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X-rays • Radiography – the “process of recording” (-graphy) x-“rays” (radi) • W.K. Röntgen – German physicist who discovered x- rays. • Produced the first radiogram – “x-ray” (radi) “record” (gram) • Fluoroscopes – “instruments that examine” (-scopes) the interior of the body by casting x-ray “shadows” (fluor) of them
Early x-ray picture
By Wilhelm Röntgen; current version created by Old Moonraker. [Public domain], via Wikimedia Commons
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X-rays, cont. • Computed axial tomography scan – (CAT scan or CT scan); modern advanced radiological scan • Tomogram – an x-ray “record” (-gram) of only a particular “cut or slice” (tom) through the body • Tomography – “the process of recording” (-graphy) these thin cuts (Layman, 2007, p. 103-104)
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The Cause of Illness • Etiology – the “study of” (-ology) disease “causes” (eti) • Etiological – “Cause-related” • When the cause for an illness is not found, it is called essential or idiopathic. • Idiopathic – “own” (idio) private “disease” (path) (Layman, 2007, p. 105
Case History Key terms from medical case history: • Palatine – “refers to” (-ine) the “roof of the mouth” (palat) • Lingual – “relates to” (-al) the “tongue” (lingu) • Pharyngeal – “relates to” (-al) the “throat” (pharynx) • Adenoids – “gland” (aden) “resemblers” (-oids) • Adenoiditis – “inflammation” (-itis) of the adenoids • Adenoid hypertrophy – “a process of” (-y) “excessive” (hyper) “stimulation or nourishment” (troph) of the adenoids
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Case History, cont. • Tonsillitis - “inflammation” (-itis) of the tonsils • Chronic – present for a long “time” (chron) • Cephalalgia – an “ache or pain condition” (-algia) located within the “head” (cephal) • Cervical – the “collar” (cervic) area of the neck • Contraindicated – “against” (contra-) something • Tonsillectomy/Adenoidectomy – “removal of” (-ectomy) the tonsils and adenoids (Layman, 2007, p. 107-109)