• MORPHOGENIC STAGE

• ORGANISING STAGE
• FORMATIVE STAGE
• MATURATIVE STAGE
• PROTECTIVE STAGE
• DESMOLYTIC STAGE

• PRESECRETORY STAGE
• SECRETORY,
• TRANSITION,
• MATURATION AND
• POSTMATURATION
Outer enamel Epithelium

Stellate Reticulum

Stratum Intermedium

Inner Enamel Epithelium

Dental Papilla
1) early ameloblast; 2)reversal of polarity; 3) the cell secretes the initial enamel; 4a) Crystallites are formed at both surfaces of
the process; 4b) Towards the end of secretion, most of the high nuclei have moved to a low position; ruffled (5a) and a
smooth (5b) surface apposed to the enamel; 6) they serve to protect the enamel surface during eruption and later will
contribute to form the junctional epithelium
growth factors (TGF-β)
dentine sialophosphoprotein (DSPP)
 basal
lamina of the pre-ameloblasts disappears.
enamel spindles
reversal of polarity.
 Cell web

preameloblasts
Secretion of enamel matrix starts from two sites:
 the final
few enamel increments, just as first few, do not contain any rod.
AMELOGENESIS IMPERFECTA
Hypocalcified enamel
Termination of amelogenesis
No true enamel
 altered junctional
epithelial attachment
serine proteases
Transverse section of prisms showing
type III keyhole pattern
Hunter–Schreger bands