ID : 4519 Inheritance • Inheritance is the transmission of genetic information from generation to generation. • Genetic information is stored in the form of DNA within the cell nucleus. Here are some key definitions that you must be aware of: • Chromosome is a thread like structure of DNA • A gene is a length of DNA which codes for a specific protein • An allele is a version of a gene • Haploid nucleus: a nucleus containing a single set of unpaired chromosomes (e.g. sperm and egg) • Diploid nucleus: a nucleus containing two sets of chromosomes (e.g. in body cells) Sex inheritance Normal human cells have 23 pairs of chromosomes. These called known as diploid cells. One of the pairs of chromosomes codes for sex inheritance. Sex inheritance depends on the presence of X and Y chromosomes. • Males have one X chromosome and one Y chromosome (XY) • Females have two X chromosomes (XX) Color Blindness • Females, having two copies of the X chromosome, are likely to inherit one dominant allele that masks the effect of the recessive allele • A female with one recessive allele masked in this way is known as a carrier; she doesn’t have the disease, but she has a 50% chance of passing it on to her offspringI • f that offspring is a male, he will have the disease because males only have one X chromosome, so this gene will always be expressed. DNA & Protein Synthesis • DNA: control cell functions by controlling production of • proteins, antibodies and receptors for neurotransmitters • DNA has 2 long strands and 4 nucleotides, AT and CG All body cells in an organism contain the same genes, but many genes in a particular cell are not expressed because the cell only makes the specific proteins it needs How proteins are made: • Made from long chains of amino acids. DNA bases are read as triplets • DNA held within the nucleus of the cell. Let us consider a particular gene (gene A) that makes a certain protein (protein A). 1) A molecule called mRNA ‘copy’ the DNA base sequences found within gene A – This is called transcription 2) mRNA molecule leaves the nucleus 3) mRNA passes through the ribosomes in the cytoplasm 4) Ribosomes ‘read’ the base sequences and assemble various amino acids in a specific order based on the base sequences – This is called translation Plenary (MCQ) 1) Which name is given to the observable features of an organism? A- alleles B- genes C- genotype D- phenotype
2) Which of these cells is haploid?
A- liver cell B- red blood cell C- sperm cell D- zygote Plenary (MCQ) MS • 1. D • 2. C Good Luck For Final exams