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Neoplastic growth
Causes in children versus adults
Theories
Genetic trigger
Environmental irritation
Cell mutation
Oncogenic virus
Assessment
Nursing diagnosis
Outcome identification and planning
Implementation
Outcome evaluation
History
Physical and laboratory examination
o Biopsy
o Staging
Hodgkin disease
o One painless, enlarged, rubbery-feeling cervical lymph
node followed by enlargement of other nodes and liver,
spleen, bone marrow, CNS; anorexia; malaise; night
sweats; elevated sedimentation rate; anemia
o Biopsy of lymph nodes; chest, abdominal CT;
lymphangiogram
Non-Hodgkin lymphoma
o Enlarged lymph glands of neck and chest; possibly of
axillary, abdominal, inguinal nodes; if mediastinal lymph
glands involved, cough or chest “tightness”; edema of
face
o Biopsy of affected lymph nodes, bone marrow
Burkitt lymphoma
o Enlarged, painless lymph node of neck or abdomen
blocking a body system; growth so rapid cell mass may
double in size in as few as 24 hours
Osteogenic sarcoma
o Taller than average; painful, swollen site; possibly
inflamed, feels warm; report of recent trauma to site
o Elevated serum alkaline phosphatase; biopsy of site
Ewing sarcoma
o Intermittent pain at site, becomes constant and severe;
“onion-skin” reaction on X-ray
o Bone scan, bone marrow aspiration, biopsy, CT scan of
lungs, and IV pyelogram or kidney MRI
Neuroblastoma
o Palpable abdominal mass after weight loss, anorexia;
possibly excessive sweating, flushed face, hypertension;
possibly abdominal pain, constipation; possibly loss of
motor function in lower extremities
o Arteriogram; ultrasound, CT, or MRI scan of chest,
abdomen, pelvis; gallium bone scan; bone marrow
aspiration and biopsy
Pain
Imbalanced nutrition
Risk for infection
Disturbed body image
Compromised family coping
Radiation therapy
o Immediate side effects
o Long-term side effects
o Effects on bone
o Effects on hormones
o Effects on nervous system
o Effects on organs of chest, abdomen
Radiation therapy—(cont.)
o Before treatment
o During treatment
o After treatment
Chemotherapy
o Types
Alkylating agents
Antimetabolites
Plant alkaloids
Antitumor antibiotics
Chemotherapy—(cont.)
o Types—(cont.)
Nitrosoureas
Corticosteroids
Immunotherapy
Chemotherapy—(cont.)
o Protocols
o Side effects and toxic reactions
Alopecia
Cushingoid appearance
C. Abdominal mass
Rationale: A Wilms tumor grows on the anterior surface of
the kidney, so it is felt as an abdominal mass.