Amides

Amides contain one or

more nitrogen atoms
Amides are the product of
reaction between an amino
and a carboxylic acid and
derivative.
Simple Amides are soluble in
water
Amides do not behave like
bases
Amides are mainly solids at
room temperature and have very
high boiling points.
General Formula:
CO-NH
- It is an interaction between
an amino ( NH2 ) group and
a carbonyl ( CO2H ) group
Functional Group:
An amide functional group consist of a
carbonyl group bonded to a nitrogen.
In simple amides, two hydrogen atoms
are bonded to the nitrogen ( -CONH2 )
while in more complex amides, the
nitrogen is bonded to one or two
aliphatic or aromatic groups (
Functional Group:
O
R C
NH2
- Oxygen double bonded to carbon.
Amino and derivative connected to
carbon
Properties of Amides
Depending upon the structure and
the functional group, the main
physical properties of amides can
be categorized as:
Solubility, Basicity, Melting
and Boiling Point
Examples
and Uses
Examples:
Examples of amides include
carboxanamides, sulfonamides,
and phosphoramides. Nylon is a
polymide. Several drugs are
amides, including LCD, penicillin,
and paracetamol.
Uses:
Amides may be used to form
resilient structural ( e.g., nylon,
Kevlar). Dimethylformamide is an
important organic solvent. Plants
produce amides for a variety of
functions. Amides are found in many
drugs.
Nomenclature:
Examples
: O CH3 O
NH2 NH2
Ethanamide 3-
Methylbutanamide
Rules:
1. Amides are amine derivatives of
carboxylic acids
2. The root name is based on the
longest chain including the
carbonyl group of the amide
group.
Rules:
3. Since the amide group is at the
end of the chain, the C=O carbon
must be C1.
4. The amide suffix is appended after
the hydrocarbon suffix minus the “e”;
e.g. –ane + -amide =anamide etc
Rules:
5. If the amide nitrogen is
substituents are given- as the
6. The N-locant is listed first.
locant.
 Prepared By:

Angelo Banan
Josue Macarilay
Joyce Sibal