Professional Documents
Culture Documents
By
Bisrat Zeleke (Bsc.N, Msc.N Ass’t prof)
Course outline
– Course title: Nursing Research Methodology
– Program: Nursing
– Course code: Nurs 2103
– Degree Program: BSc Nursing
– Module Name: Health system research
– ECTS credits: 3 ECTS
– Contact hours: 32 hrs
– Target Group: BSC nursing students
– Year: III
– Status of the course: Major
– Pre-requisite: Biostatistics and epidemiology
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Course outline…..
Course description
Date…… 30/06/13
date 25/06/13
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Course outline…..
Course Policy
• Attendance: It is compulsory to come to class on time and every time. The students
are allowed to attend the class 100%. If you are going to miss one class during the
term without valid reason, you aren’t allowed to seat in the final examination.
• Quiz: Quiz will be given randomly at any time in the class room
• Cheating/plagiarism: Students must do their own work and not copy and get
answers from someone else. Any sort of cheating/plagiarism will result in
disqualification that work and disciplinary measures as per the university’s
legislation
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Course outline…..
References:
Title Author
1. Research methodology for HSS Getu D., Tegbar Y., 2006
2. Research strategies for health WHO, 1992
3. Writing research papers Nelissa walker, 1984
4. Principles and practice of Epidemiology M.Fletcher, 1992
5. Survey research methods Earl R. Babbie, 1973
Introduction to Research
Methodology
Chapter One
Learning Objectives
After completing this chapter, the student should be able
to:
1. Define research in general and health systems research
in particular
2. Enumerate the characteristics of research
3. Identify the different types of research
4. List the essential features of health systems research
5. Describe the broad divisions (steps) involved in the
research process
6. Explain the roles of research in development
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Chapter One
– Research is a systematic collection, analysis and
interpretation of data to generate new knowledge
and answer a certain question or solve a problem.
– We may think the answer is obvious, common sense even But until
we have subjected our problem to rigorous scientific scrutiny, our
'knowledge' remains little more than guess work or at best
intuition.
It requires a plan
negative findings
1. Based on Functions:
– Basic/fundamental…………..(building knowledge)
undertaken to extend the base of knowledge in a
discipline, or to formulate or refine a theory.
– Applied /action/operational……..(solution to
problems) Applied research focuses on finding
solutions to existing problems.
Biomedical, clinical…………….individual
Qualitative research:
– Is concerned with subjective assessment of attitudes,
opinions and behavior.
– Must be timely.
– Identifying a problem
– Preparing a research proposal
– Dissemination and
– Application of results
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Planning
Problem research
identification
Implementing
research
Applicati
on
Disseminatin
g
findings
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Chapter One….
Components of a Research Proposal
1. Preliminary part
– Acknowledgement
– Table of Contents
– List of Tables
– List of Figures
– Acronym/ Abbreviation
– Abstract / Summary (background, objective/aim, method, key words,
budget summary )
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Chapter One….
2. Body of the report
Chapter one
INTRODUCTION
Background information
Statement of the problem
Chapter two
Literature review
Conceptual/theorotical framework
Justification of the study / Significance of the study
Chapter Three
OBJECTIVES/ Hypothesis
General objective
Specific objectives
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Chapter One….
Chapter Four
METHODOLOGY/ Method and Materials
Study area and period
Study design/ type
Population (source population, study population, study unit)
Inclusion and exclusion criteria
sample size determination
sampling techniques/sampling procedure
Plan for Data collection procedures (instrument, personnel, data quality
control)
Plan for data processing and analysis
variables of the study
Operational definition (if any)
Data quality control management/ techniques
Ethical consideration
Dissemination plan
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Chapter One….
Chapter Five
WORK PLAN
Chapter Six
BUDGET
References
– List of Figures
– List of Tables
– Acknowledgement
Chapter two
Literature review
Justification of the study / Significance of the study
Chapter Three
OBJECTIVES/ Hypothesis
General objective
Specific objectives
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Chapter One….
Chapter Four
Chapter Six
Discussion
Chapter Seven
Conclusion and Recommendation
References
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Chapter One….
3. Supplementary part
Annex
Data collection instruments (questionnaire, interview guide)
Declaration
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Chapter Two
4. Identify and select his/her own topic (health problem) for research
based on certain guidelines.
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Chapter two….
– The development of a health project goes through a
number of stages.
– Discrepancy: All the 500 children at district “Y “should have completed their
vaccination but only 5% out of those who started vaccination have completed.
– Definite answer: Out of the 1 hospital, 2 health centers and 10 health stations
found in district “Y” only 2 health stations were functioning, the rest were
closed
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Chapter two….
– Is it researchable or not??????
– One good way to cut the length of titles is to avoid words that
add nothing to a reader's understanding, such as "Studies
on...," "Investigations...," or "Research on Some Problems in...."
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Chapter two….
Title:
The title should be written in a way that:
Indicate study subjects, study design, study area, objective of the study
and study period
Word length on average (5-14)
Have two title pages
First title page contains
The tile of the study, name of the researcher(s) with his/her title, name of
Department to be submitted/institution with date of submission
Second title page
In addition to those things in the 1 st page, name of the advisors and examiners will also
included here.
Not more than 20 word
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Chapter two….
Exercises
1. In a certain district (population, 150,000), sanitary
conditions are very poor (only 5% of households have
latrines) and diseases connected with poor sanitation,
such as, gastroenteritis and worms are very common.
The Ministry of Health has initiated a sanitation project
that aims at increasing the number of households with
latrines by 20% each year. The project provides materials
and the population should provide labour. Two years
later, less than half of the target has been reached.
– State the discrepancy, research question and the possible
answers.
– Is this problem situation researchable?
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Chapter two….
2. Walk around and identify three health problems in the
university compound. Discuss about these health
problems and rate them based on the selection
criteria.
Relevance
Avoidance of duplication
Feasibility
Political acceptability
Applicability
Ethical acceptability
Total
Problem statement
Chapter Three
Learning objectives
After completing this chapter, the student should be able to:
1. Describe the advantages of a systematic analysis of a
problem
• An analysis of the major factors that may influence the problem and a
convincing argument that available knowledge is insufficient to answer a
certain question and to update the previous knowledge.
• A brief description of any solutions that have been tried in the past, how
well they have worked, and why further research is needed.
Literature Review
Literature Review
Learning objectives
– After completing this chapter, the student should be able to:
1. Describe the reasons for reviewing available literature
and other information during the preparation of a
research proposal.
LR by Ayele S 71
Literature Review…..
A literature review is the effective evaluation of selected
documents on a research topic.
LR by Ayele S 72
Literature Review…..
A .‘good’ literature review….. A ‘poor’ literature review is…
way
LR by Ayele S 73
Literature Review…..
Purpose
Provide you with a handy guide to a particular topic.
It prevents you from duplicating work that has been done before.
LR by Ayele S 74
Literature Review…..
It increases your knowledge on the problem you want to study and
this may assist you in refining your "statement of the problem".
LR by Ayele S 75
Literature Review…..
LR by Ayele S 76
Literature Review…..
In a broader context Hart (1998) lists the following
purposes of a review:
– Distinguishing what has been done from what needs to be
done;
77
Literature Review…..
– Rationalizing the significance of the problem;
78
Literature Review…..
– Describe the relationship of each work to the others under
consideration
– Identify new ways to interpret, and shed light on any gaps in,
previous research
Sources of information
Journal articles: these are good especially for up-to-
date information.
82
Literature Review…..
Newspapers/Magazines:
Since they are intended for a general (not specialized)
audience, the information they provide will be of very limited
use for your literature review.
Often they are more helpful as providers of information about
recent trends, discoveries or changes.
Government/corporate reports:
Their published findings can provide a useful source of
information, depending on your field of study.
83
Literature Review…..
Theses and dissertations:
Can be useful sources of information. However there are
disadvantages:
84
Literature Review…..
Internet:
The fastest-growing source
It is impossible to characterize the information available
but here are some hints about using electronic sources:
Internet Search tools
Gateways
Databases eg. PubMed (database)
Search Engines eg.www.scholar.google.com,
Yahoo
Search widely: Library, Electronic search engines, Grey literature
85
Literature Review…..
86
Literature Review…..
87
Literature Review…..
CARRYING OUT A LITERATURE SEARCH
It outlines good practice in how to undertake a
literature search i.e., how to:
o Set search parameters
o Identify appropriate databases
o Write the search strategy and
o Record the results.
88
Literature Review…..
CARRYING OUT LR
• After collecting the required information, the
investigator should decide in which order he/she
wants to discuss previous research findings:
89
Literature Review…..
First, cover the basic categories
90
Steps for Writing a Literature Review
1. Planning: What Type of Literature Review am I Writing?
Focus, type, scope, Academic Discipline, etc
2. Reading & Research: What Materials am I Going to Use?
Collect and read material,
Summarize sources
Select only relevant books and articles.
3. Analyzing: How Do I Assess Existing Research?
A literature review is never just a list of studies—it always
offers an argument about a body of research.
Four Analysis Tasks: Summarize, Synthesize, Critique,
compare
4. Drafting: What Am I Going to Write? Organizing
Five common approaches to organize: Topical/Thematic,
Distant to close, Debate, Chronological, Seminal Study
5. Revising: How Can I modify My Draft?
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Literature Review…..
Ethical considerations
• Careless presentation and interpretation of data may put readers
who want to use the study’s findings on the wrong track
Research Objectives
Chapter Five….
Learning objectives
After completing this chapter, the student
should be able to:
1.Describe the need for the development of
research objectives
2. Differentiate between general and specific
objectives
3. Formulate specific objectives and hypotheses
General objectives:
Is the aim of the study in general terms
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Chapter Five….
Specific objectives:
Logically connected parts of the general objective
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Hypothesis Vs Research questions
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Chapter Six
Research communication:
The process of sharing research findings to the target
audiences with appropriate channels to influence
decision makers and to boost up the existing knowledge.
Research Report:
Before writing the report the researcher must know his or her
audience.
A. Technical report
B. Management report
A) Technical report:
Written for an audience of research community.
Technical reports has two types:
1. Long technical reports
2. Short technical report
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Chapter Six….
B. Management reports
– Designed for a non- technical audiences such as policy makers, study
communities etc
– Readers are less concerned with methodological details
– But they are more interested in learning quickly the major findings and
conclusions.
– The style of the report should encourage rapid reading and quick
comprehension of major findings
– Sentences and paragraphs should be short and direct.
– use of visual displays more sound and simplify
First draft:
Finding, discussion & conclusions has been completed.
Working group members and facilitators should read
critically & forward comments.
Second draft:
The authors may prepared a second draft taking in to
considerations all comments that have been made.
Final draft:
The facilitators & different groups read the 2nd draft again, then
the final version of the report will be prepared after
incorporating comments.
Contents:
• Includes table of content , list of figures and tables
Table of content:
• Should include all content of the document with their respective
pages and sequential order
• Formatting with heading and sub heading
List of figures and tables:
Put them with full tile and page numbers in different pages with
order of list of table followed by list of figures
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Chapter Six….
• When you write abbreviation or acronyms first you have state the
full form
Background
• Present general facts, truth and trends in your topic
• Clarify how your work adds important findings
• Try to briefly discuss what is known in the area and the gap that
should be filled by your research.
Conceptual Maps
• A conceptual map is simply a diagram of the concepts and
relationships expressed in a theoretical/conceptual framework.
Study Variable
The dependent(outcome of interest) and independent
variables should be identified and stated clearly
Data collection methods and tools
Consider both qualitative and quantitative data collection
techniques based on our design and objective.
Describe about data collectors, procedures, number of days,
data collection tools and technique.
• State the limitation of your study design and other problems that
encounter during your study
Reference:
– Those references used in the study should be included here
– Be consistent while putting references throughout the
whole document(don’t mix different styles in one
document)
– There are two style of writing references commonly used
1. Vancouver system.
2. Harvard system
Authors:
Author(s)’Surname followed by initials. Title of article. Name of
Journal. Year, Volume,(number): the first and last page numbers of
the article.
Example :
Deressa W, Hailemariam D, Ali A. Economic costs of epidemic
malaria to households in rural Ethiopia. Tropical Medicine and
International Health;2007;12(10):1148-1156.
List all authors, but if the number exceeds six, give the
first six followed by “et al” (but can vary from journal to
journal)
Example :
Rose ME, Huerbin MB, Melick J, Marion DW, Palmer AM,
Schiding JK, et al. Regulation of interstitial excitatory amino
acid concentrations after cortical contusion injury.
International journal of Health; 2002;935(2):40-6.
Internet Sources:
• Author, initials, title, date retrieved (accessed), retrieved from, full
website address.
Example:
• WHO and UNAIDS. Guidance on provider-initiated HIV testing
and counseling in health facilities. Geneva, World Health
Organization,2007 (http://www.who.int/hiv/pub/vct/pitc2007/en,
accessed 1 September 2009).
Harvard(author-date) System.
• This system uses the author's name and date of publication in the
body of the text, and it is listed alphabetically by author name on
the reference page.
Research utilization:
The stage where by research findings are used for decisions
making during policy formulation, resource allocation,
planning and management, program systems development and
strengthening and adaption of science and technology.
Needs multi desplenary efforts and coordination's to change
findings in to practice .
Despite its indispensable role for decision making, many
researches remains on the shelf due to several reasons.
Importance of Dissemination
– Advancement of scientific knowledge.
– Developing evidence-based practice
– Increase the access for research
– Planning for change and innovation
– Promote research finding implementation
Methodology
Chapter seven
Methodology
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Chapter seven….
Study design
– A study design is a specific plan or protocol for conducting the
study, which allows the investigator to translate the conceptual
hypothesis into an operational one.
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Types of Epidemiological Studies
Populations Ecologic
Descriptive Case-series
Individuals
Cross-sectional
Case-control
Observational
Prospective
Cohort
Analytical
Retrospective
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Descriptive studies:
Advantages
– Important link between clinical medicine and epidemiology.
– One of the first steps in outbreak investigation.
– Often useful for hypothesis generating and examining new
diseases.
Disadvantages
–Can’t be used to test hypotheses
–Based on the experience of one or few people
–Lacks comparison group
Intervention/experimental studies:
The researcher manipulates objects or situations
and measures the outcome of manipulations.
Selection of Controls
• Be comparable to the cases: as similar to a case as possible but without the
disease in question
• Must have the same opportunity for exposure as a case
• Must be subject to the same inclusion and exclusion criteria as cases
• Involves consideration of a number of issues: Scientific, economic and
practical considerations
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II. Cohort studies:
Study groups identified by exposure status prior to
ascertainment of their disease status
What is a cohort?
• A group of persons
– sharing the same experience
– followed for a specified period of time
• Examples
– birth cohort
– workers at a chemical plant
– graduating university class
– Attendants of this course
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Chapter seven….
Prospective
Retrospective (historical)
Limitations:
• Is inefficient for the evaluation of rare diseases
• Expensive and time consuming
• Validity of the results can be seriously affected by losses to
follow-up
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Chapter seven….
– Sampling involves+
– the selection of a number of study units from a defined
study population.
to draw a sample?
Example:
• You want to carry out a survey of 100 voters in a small
town with a population of 1,000 eligible voters. We could
write the names of all voters on a piece of paper, put all
pieces of paper into a box and draw 100 tickets at random.
You shake the box, draw a piece of paper and set it aside,
shake again, draw another, set it aside, etc. until you had
100 slips of paper. These 100 form your sample. And this
sample would be drawn through a SRS procedure - at each
draw, every name in the box had the same probability of
being chosen.
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2. Systematic random Sampling:
Technique:
• Desired sample size is established at some number (n).
222
Chapter seven….
than SRS.
• The first step is to find the total number of students (300) and
calculate the percentage in each group.
• Male, Regular = (50 / 300) x 100 =17
Total = 50
By Proportionate stratified sampling
227
Chapter seven….
Section 1 Section 2
Section 3
Section 5
Section 4
231
Chapter seven….
5. Multi-Stage Sampling:
Is appropriate when the population is large and widely
scattered.
Example:
• After selection of a sample of clusters (e.g.
household), further sampling of individuals
may be carried out within each household
selected. This constitutes two-stage sampling,
with the PSU being households and the SSU
being individuals
Disadvantage:
– less precise than SRS.
235
Chapter seven….
237
Chapter seven….
1. Volunteer/self selection Sampling
– Selected subjects are volunteers who show interest to participate in the
study.
– Common in trials demanding long duration.
– Payments for subjects some times be involved.
• Primarily used when there is a limited number of people that have expertise
in the area being researched
The nurse who conducts an observational study of women delivering twins at the
local hospital is also relying on a convenience sample.
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Chapter seven….
4. Quota sampling
• Is a method that ensures a certain number of sample from different
categories with specific characteristics appear in the sample so that all these
characteristics are represented.
• The population is first segmented into mutually exclusive sub-groups as in
stratified sampling.
• Stratification should be based on one or more variables that would reflect
important differences in the dependent variable under study like (age,
gender, ethnicity, educational attainment, medical diagnosis etc).
• Convenience is used to select subjects until a specific number of units/quota/
for various sub-groups has been filled.
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Chapter seven….
5. Snowball
– Is usually done when there is very small population size.
– Involves a process of “chain referrals”
– Start with one or two key informants and ask them if they know
persons who know a lot about the topic of interest.
– Used when trying to interview hard to reach groups.
242
Errors in sampling procedures
•When taking a sample, the results will not exactly equal to results for the population. i.e. it will
be subject to error.
•This error has two components: sampling and non-sampling errors.
a) Sampling error (i.e., random error)
•Random error, consists of random deviations from the true value, which can occur
in any direction.
•Sampling error (random error) can be minimized by increasing sample size.
•Opposite of random error is reliability.
Reliability (or precision): : This refers to the repeatability of a measurement.
•Is about degree of closeness between repeated measurement of the same value.
•Reliability addresses the question, if the same thing is measured several times, how close are
the measurements to each other?
The sources of variation resulting in poor reliability include:
-Variation in the characteristic of the subject being measured. E.g.: blood pressure
-The measuring instruments, e.g. questionnaires
-The persons collecting the information (observer variation)
Inter-observer variation: differences between observers in measuring the same observation
Intra-observer variation: differences in measuring the same observation by the same observer
on different occasions.
b) Non Sampling error (i.e., bias)
•Bias, consists of systematic deviations from the true value, always in the
same direction.
•It is possible to eliminate or reduce the non-sampling error (bias)
by careful design of the study procedures.
•The opposite of bias is validity.
Validity: This refers to the degree of closeness between a measurement
and the true value of what is being measured.
• Validity addresses the question, how close is the measured value to
the true value?
•To be accurate, a measuring device must be both valid and reliable.
•However, if one cannot have both:-
– validity is more important in situations when we are interested in the
absolute value of what is being measured.
– Reliability on the other hand is more important when it is not essential to
know the absolute value, but rather we are interested in finding out if
there is a trend, or to rank values.
Examples of types of bias in sampling include:
• Bias resulting from incompleteness of the sampling frame, accessibility bias,
seasonality bias, self-reporting bias, volunteer bias, non-response bias etc.
Non-response bias: is failure to obtain information on some of the study subjects. It
results in significant bias when the following two situations are both fulfilled.
– When non-respondents constitute a significant proportion of the sample.
– When non-respondents differ significantly from respondents
A). Non-response should be considered during the planning stage of the study and
Non-response should be kept to a minimum. E.g. below 15%.
Methods that may help in maintaining non-response at a low level could be:
• Subjects should be contacted in a respectful way and convinced about the study
• Incentives to encourage participation. but, consider potential problems in the
future.
• making repeated attempts to contact study subjects who were absent at initial
visit.
B).The number of non-responses should be documented according to type, so as to
facilitate an assessment of the extent of bias introduced by non-response.
C). As much information as possible should be collected on non-respondents, so as
to see in what ways they may differ from respondents.
alid
Neither Valid
nor Reliable
not V
e but
bl
Relia
Validity and Reliability
b le
Relia
id &
Val
Tadesse, Chanyalew & Yeshitila 246
Sample size determination
255
Example: The proportion of nurses leaving the health service is compared
between two regions. In one region 30% of nurses is estimated to leave the
service. In other region it is probably 15%. The required sample to show, with
a 90% likelihood (power), that the percentage of nurses is different in these
two regions would be:
Given: α= 5% (assume a confidence level of 95%) ,β= 90%, P1= 0.3, q1= 0.7,
p2= 0.15 q2=0.85
Solution: n = (1.28+1.96) ² ((.3×.7) +(.15 ×.85)) / (.30 - .15) ² = 158
• 158 nurses are required in each region
Sample size for comparison of two means (sample size in each group):
n = (s1² + s2² ) (z1-α +z1-β) ² / (m1 - m2)²
Where, m1 and s1 are mean and standard deviation of group 1 respectively.
• m2 and s2 are mean and standard deviation of group 2 respectively
•Having decided on how to design the research study, the next is how to
collect information.
•Practical and resource considerations, such as, the need for personnel,
time, equipment and other facilities, in relation to what is available.
Self-administered questionnaire:
•the respondents read the questions and fills in the answers by themselves
• sometimes interviewer may be present, who stands by to give assistance if
necessary.
•The use of self-administered questionnaires is simpler and cheaper
•such questionnaires can be administered to many persons simultaneously.
Questionnaire Design
4. Information bias:
• Sometimes the information itself has weaknesses.
• Medical records may have many blanks or be unreadable. This tells something
about the quality of the data and has to be recorded.
• Another common information bias is due to gaps in people’s memory; this is
called memory or recall bias.
– E.g. A mother may not remember all details of her child’s last diarrhoea
episode and of the treatment she gave two or three months ago.
Data processing and analysis
• Data processing and analysis should start in the field, with checking for
completeness of the data and performing quality control
• Data of small samples may even be processed and analyzed as soon as
collected.
• a data processing and analysis issues should include the following :
– Sorting data
– Performing quality-control checks
– Data processing and
– Data analysis
Sorting data:
• Sorting the data is important for facilitating subsequent processing and
analysis.
• If you have different study populations (for example village health workers,
village health committees and the general population), you obviously would
number the questionnaires separately.
• In a comparative study it is best to sort the data right after collection into the
two or three groups that will be compared.
Performing quality control checks
• Usually the data have already been checked that all information has been
properly collected and recorded.
• Before and during data processing, the information should be checked again
for completeness and internal consistency.
• If a questionnaire has not been filled in completely you will have MISSING
DATA for some of your variables.
• If there are many missing data in a particular questionnaire, you may decide to
exclude the whole questionnaire from further analysis.
• If an inconsistency is clearly due to a mistake made by the researcher/research
assistant it may still be possible to check with the person who conducted the
interview
• If the inconsistency is less clearly a mistake in recording, it may be possible (in
a small scale study) to return to the respondent and ask for clarification.
• If it is not possible to correct information that is clearly inconsistent
• If a certain question produces ambiguous or vague answers throughout, the
whole question should be excluded from further analysis.
• For computer data analysis, quality control checks of data must also include a
verification of how the data has been transformed into codes
Data processing – quantitative data
• A GANTT chart is a planning tool that depicts graphically the order in which
various tasks must be completed and the duration of each activity. The length of
each task is shown by a bar that extends over the number of days, weeks or
months the task is expected to take.
• A management tool for the Team Leader and members of the research
team, showing what tasks and activities are planned, their timing, and
when various staff members will be involved in various tasks.
• A tool for monitoring and evaluation, when the current status of the
project is compared to what had been foreseen in the work plan.
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Chapter Eight…..
Budget
Why do we need to design a budget?
• A detailed budget will help you to identify which
resources are already locally available and which
additional resources may be required.
• The budget for the fieldwork component of the work plan will
include funds for personnel, transport and supplies.
• Note that UNIT COST (e.g., per diem or cost of petrol per km), the
MULTIPLYING FACTOR (number of days), and TOTAL COST are
required for all budget categories.
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Chapter Eight…..
Budget justification
• It is not sufficient to present a budget without explanation.
• Make sure you give clear explanations concerning why items that may
seem questionable or that are particularly costly are needed and discuss
how complicated expenses have been calculated.