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Malaria Treatment Protocol: Third Edition
Malaria Treatment Protocol: Third Edition
Third edition
June 2007
Ministry of Health
Republic Democratic of Timor- Leste
UNCOMPLICATED MALARIA
Uncomplicated malaria definition:
Fever and any of the following:
Headache,
Spleenomegaly
Confirmed Diagnosis of Malaria
All clinically suspected malaria cases require
laboratory examination and confirmation.
Only in case where laboratory confirmation is
not possible start treatment immediately.
Parasitological confirmation is done by thin-
thick blood smear microscopy examination or
by dipstick (Rapid Diagnostic Test [RDT]).
Differential diagnosis for
uncomplicated malaria
Consider other illnesses, such as:
Upper respiratory tract infection
(Pharyngitis, tonsillitis, ear infection),
pneumonia , measles, dengue, influenza,
typhoid fever.
Remember that the patient may be suffering
from more than one illness.
Uncomplicated malaria treatment
P. falciparum malaria
The treatment of uncomplicated P. falciparum
malaria is undertaken after diagnosis of
malaria by light microscopy or Dipstick.
Patients with positive think-thick blood
smears or dipstick for P. falciparum malaria
is treated by blisters of Coartem® (artemether
20mg/lumefantrine 120mg). See Table 1 for
details of prescription.
Table 1 : Dosage and administration Coartem (Artemether 20
4 months 1 tb , 1 tb , 1 tb ,
5 to 14 kg Yellow
to 5yrs
1 tb 1 tb 1 tb
2 tb , 2 tb , 2 tb ,
6 to 11y 15 to 24 kg Blue
2 tb 2 tb 2 tb
3 tb , 3 tb , 3 tb ,
12 to 14y 25 to 34 kg Orange
3 tb 3 tb 3 tb
4 tb , 4 tb , 4 tb ,
> 14y > 34 Green
4 tb 4 tb 4 tb
Weight
Age Group Artesunate or *Quinine
group
Oral
** IM first dose Quinine 10
***Oral
Artesunate 1.2 mg/TID for
0-4 Artesunate
<5 kg mg/kg or IM 4 days
months 2mg/kg/day
Arthemeter 1.6 then 15-20
day 2 to day 7
mg/kg) mg/kg TID
for 4 days
Source: Malaria in Children, Department of tropical Pediatrics, Faculty of Tropical Medicine, Mahidol University.
CHLOROQUINE
PRIMAQUINE
(150 mg base) 10 mg/kg on the
(15 mg base)
first two days.
* Weight 0.5 mg/kg bw
Age Group 5 mg/kg on day 3
group (Kg)
Give for 3 days
Start concurrently with CQ
Day 1 Day 2 Day 3 and give daily for 14 days
4 months up
4 - <10 ½ ½ ¼ -
to 12 months
13 months up
10 - <19 1 1 ½ ¼
to 5 years
6 - 7 years 19 - < 24 1½ 1½ 1 ½
8 - 11 years 24 - <35 2½ 2½ 1 ¾
12 - 14 years 35 - < 50 3 3 2 1½
15 + 50 or more 4 4 2 2
P. vivax malaria
Young infant less than 5kg or below 4
months should be treated with Chloroquine
alone for three days consecutive (Table 4b).
Table 4b. Dosage and administration of Chloroquine
for malaria vivax in young infant
Chloroquine
Age Weight
Group group
Day 1 Day 2 Day 3
0-4
<5 kg 10 mg/kg 5 mg/kg 5 mg/kg
months
P. falciparum and P. vivax
(mixed infections)