INTRODUCTION TO

MICROBIAL PATHOGENICITY
PRESENTED BY
GBADAMOSI DAMILOLA RUTH
MCB/2016/160

SEMINAR SUPERVISOR
DR. J. OMOLOLU-ASO

SEMINAR COORDINATOR
DR. O.O. OMOBOYE
1
 OUTLINE OF THIS PRESENTATION
• INTRODUCTION—INFECTIONS AND THEIR TRANSMISSION

• WHAT IS MICROBIAL PATHOGENICITY?

• TRANSMISSION OF INFECTION

• CHAIN OF INFECTION

• MICROBIAL MECHANISMS OF PATHOGENICITY

• FACTORS AFFECTING BACTERIAL PATHOGENICITY

• INFECTION CONTROL STRATEGIES

• CONCLUSION 2
WHAT IS MICROBIAL PATHOGENICITY?
• Pathogenicity
The ability of an infectious agent to
cause disease in a host
• Virulence
The degree of pathogenicity, the ability
of the pathogen to infect or damage the
host
• Portal of entry
The specific route by which a particular
pathogen gains access to the body

3
INTRODUCTION—INFECTIONS AND THEIR TRANSMISSION

• Infection is the invasion of an organism’s

body tissues by disease-causing agents, their
multiplication and the reaction of host tissues
to these organisms and the toxins they produce

• A number of infections have been a cause of

public health crisis over time with novel
methods of containing them coming into play
daily

4
TRANSMISSION OF INFECTION
Types of infectious diseases:
There are three links in the chain
Bacteremia—circulation of bacteria in the
of transmission of communicable blood
diseases:
Septicemia—toxins multiplication in
Reservoir blood stream
Mode of transmission Pyaemia—when a pyogenic bacteria
produces septicemia with multiple
Mechanism of microbial absceses in internal organs
pathogenicity
Inflammations—pharyngitis,
Gastroenteritis,
etc
5
CHAIN OF INFECTION

6
MICROBIAL MECHANISMS OF PATHOGENICITY

7
FACTORS AFFECTING BACTERIAL PATHOGENICITY

8
INFECTION CONTROL STRATEGIES

9
CONCLUSION
Microbial pathogenicity transcends a number of complex disciplines. It
has also been observed that microorganisms adapt to life within a host
by altered expression of several genes. Identification and
characterization of these genes will provide new insights into microbial
pathogenesis.

10
11