treatment for IC

U
① cefteriaxon
② Gentomycin
③ ampicillin
④ Declofenic
⑤ hydrocortisone
⑥ Dexomizon
⑦ adranel
⑧ ibuprofen
⑨ silver sulfadiaxon
Deffination ceftriaxon
e
• Ceftriaxone is a broad-spectrum third-generation ce
phalosporin antibiotic.1
machanical action of ceftriaxone

Mechanism of action

Ceftriaxone selectively and irreversibly inhibits bact

erial cell wall synthesis by binding to transpeptidase
s, also called transamidases
n infections caused by bacter

indication
d disease),

he female reproductive organ

at surround the brain and spi

act, blood, bones, joints, an

en before certain types of sur

side effects
rash,
diarrhea,
nausea,
vomiting,
upset stomach,
blood clots,
dizziness,

headache,
 contraindications
e the red blood cells burst call

born child

h Clostridium difficile bacteria

Gentomycin

part two
Gentomycin
This medication is used to prevent or treat a wide v
ariety of bacterial infections. Gentamicin belongs to
a class of drugs known as aminoglycoside antibiotic
s
machanicalaction of Gento

Gentamicin is bactericidal and is a broad spectrum

antibiotic (except against streptococci and anaerobi
c bacteria). Its mechanism of action involves inhibiti
on of bacterial protein synthesis
indication of Gentomyc
in
• Gentamicin (gentamicin injection pediatric) Injection is indicated in the treatment
of :-

① serious infections caused by susceptible strains of the following microorganism

s:-

② Pseudomonas aeruginosa,

③ Proteus species (indole-positive and

④ indole-negative),

⑤ Escherichia coli,

⑥ Klebsiella-Enterobacter-Serratia species, Citrobacter ...

side effects
nausea.

vomiting.

diarrhea.

decreased appetite.

pain at the injection site.

headache.

fever.

joint pain.
contraindications
① low amount of calcium in the blood

② dehydration

③ a type of movement disorder called parkinsonism

④ myasthenia gravis

⑤ a skeletal muscle disorder

⑥ ringing in the ears

⑦ disorder of nerve that controls hearing and balance

⑧ decreased kidney function

⑨ sensation of spinning or whirling

⑩ pregnancy

⑪ food poisoning of infant

ampicillin

third drug
overveiw
• Ampicillin is an antibiotic used to prevent and treat
a number of bacterial infections, such as respiratory
tract infections, urinary tract infections, meningitis,
salmonellosis, and endocarditis. It may also be used
to prevent group B streptococcal infection in newbo
rns
machanical action
Ampicillin acts as an irreversible inhibitor of the enz
yme transpeptidase, which is needed by bacteria to
make the cell wall. It inhibits the third and final stag
e of bacterial cell wall synthesis in binary fission, wh
ich ultimately leads to cell lysis; therefore, ampicilli
n is usually bacteriolytic.
indication for ampicillin
① For the treatment of severe infections, including bacteremia.

② For the treatment of meningitis. ...

③ For the treatment of infective endocarditis.

④ For the treatment of upper respiratory tract infections (URTI

s)

⑤ lower respiratory tract infections (LRTIs), including communit

y-acquired pneumonia (CAP).
side effects of ampicilli
n
① acute inflammatory skin eruption (erythema multiforme)

② redness and peeling of the skin (exfoliative dermatitis)

③ rash.

④ hives.

⑤ fever.

⑥ seizure.

⑦ black hairy tongue.

⑧ diarrhea.
contraindications
Dialysis, renal disease, renal failure, renal impairment
. ...
Asthma, carbapenem hypersensitivity, cephalosporin
hypersensitivity, eczema, penicillin hypersensitivity, s
erious rash, urticaria. ...
Mononucleosis. ...

• Antimicrobial resistance.
declofenic
fourth-

part
declofenic
• is a nonsteroidal anti-inflammatory drug used to tre
at pain and inflammatory diseases such as gout. It i
s taken by mouth, rectally in a suppository, used by
injection, or applied to the skin. Improvements in p
ain last for as much as eight hours.
machanical action of declof
enic
diclofenac exerts its action via inhibition of prostagl
andin synthesis by inhibiting cyclooxygenase-1 (CO
X-1) and cyclooxygenase-2 (COX-2) with relative equ
ipotency.
indication for declofe
nic
 Diclofenac is a medicine that reduces inflammatio
n and pain.

 It's used to treat aches and pains, as well as proble

ms with joints, muscles and bones. These include: r
heumatoid arthritis, osteoarthritis and gout
side effects of declofenic
 The most common side effects are headaches, dizz
iness, stomach pain, feeling or being sick, diarrhoea
and rashes. Diclofenac tablets come as either diclof
enac potassium or diclofenac sodium.
contraindications of declofenic
I. meningitis not due to an infection.

II. systemic mastocytosis.

III. dehydration.

IV. hepatic porphyria.

V. anemia.

VI. increased risk of bleeding due to clotting disorder.

VII. an increased risk of bleeding.

VIII.alcoholism.
•Diazepam

Part five
Deffinition of diazepam
• is used to treat anxiety, alcohol withdrawal, and sei
zures. It is also used to relieve muscle spasms and t
o provide sedation before medical procedures
Mechanism of action of di
azepam
• Diazepam is a benzodiazepine. Benzodia
zepines presumably exert their effects b
y binding at stereo specific receptors at
several sites within the central nervous
system.
 Indication of diazepam

• Status epilepticus
• Sedation (for procedures)
• Muscle Spasm.
• Seizures
 Contraindication
• Respiratory depression, especially seen
with coexistent respiratory disease or m
yasthenia gravis; There is potential for g
rowing dependence, therefore only sho
rt-term use is recommended; Acute por
phyria.
 Side effect of diazepa
drowsiness m
dizziness
tiredness
muscle weakness
headache
dry mouth
nausea
constipation
confusion
difficulty urinating
frequent urination
• changes in sex drive or ability
•Hydrocortson

•Part six
Hydrocortison
Hydrocortisone is a corticosteroid medici
ne or ‘steroid’.
• It works by damping down the body’s i
mmune response to reduce pain, itchin
g and swelling.
 Mechanism of action
• Hydrocortisone is a Corticosteroid. T
he mechanism of action of hydrocor
tisone is as a Corticosteroid Hormon
e Receptor Agonist.
Side effect of hydroco
rtison
headache
increased sweating
trouble sleeping
unusual hair growth on your face or body
upset stomach
increased appetite
nausea
 Indication
• This medication is used to treat a variety of
skin conditions (e.g., insect bites, poison oa
k/ivy, eczema, dermatitis, allergies, rash, itc
hing of the outer female genitals, anal itchi
ng). Hydrocortisone reduces the swelling, it
ching, and redness that can occur in these
types of conditions. This medication is a mi
ld corticosteroid.
 Contraindication
1.inactive tuberculosis
2.herpes simplex infection of the eye.
3.an infection due to a fungus.
4.intestinal infection caused by the roundworm Stro
ngyloides.

5.a condition with low thyroid hormone levels

6.diabetes.
7.insufficiency of the hypothalamus and pituitary gl
and.
 Cont.....
10.high blood pressure
11.chronic heart failure
12.an ulcer from too much stomach acid

13.surgical joining of two parts of the int

estine
14.hardening of the liver
15.decreased kidney function
16.osteoporosis
 Deffinition of salbatamol

Salbutamol is used to relieve symptoms of ast

hma and chronic obstructive pulmonary disea
se (COPD) such as coughing, wheezing and fee
ling breathless. It works by relaxing the muscl
es of the airways into the lungs, which makes i
t easier to breathe.
Mechanism of action