A Rare Case: ANTERIOR MEDIASTINAL

THYMIC CARCINOMA TYPE C THYMOMA T4N2M1 STAGE IVB

Rizki ROMADANI1, Indra YOVI1, Indi ESHA1, Hariadi HATTA 2, Ina RANGKUTI 3
1
Department of Pulmonology and Respirology Medicine, Medical Faculty University of Riau
2
Department of Thoracic and Cardiovascular Surgery, Medical Faculty University of Riau
3
Department of Anatomical Pathology, Medical Faculty University of Riau

Introduction
  Tn P
• Nonkeratinizing squamous cell carsinoma of thymus 47 yo
(type c thymoma) derived from thymic epithelial cells
is a rare case but mostly aggressive, easily
metastasized cancer with very poor prognosis.
• The incidence of type c thymoma is 0.06% of all
thymic neoplasms.
• The therapeutic modality is multidisciplinary
treatment such as surgery, chemotherapy and
radiotherapy.
Tn P Tn P Discussion
47 47 Diagnosis of type c thymoma is ultimately made by
yo yo histology from core needle biopsy. Debulking surgery was
not performed because the patient identified at an
Case Report advanced stage.
A 47-year-old male hospitalized at Arifin Achmad General
Hospital. Complained of breathlessness for a week
Conclusion
before admitted to hospital, right chest pain, swollen of
the neck and right hand for a month. Mass found at Type c thymoma requires special attention because it is
region lymph node at colli dextra size 7x4x2 cm soft mostly found at an advanced stage.
consistency and no pain. His blood counts leukocytosis Histopathological Result
and increased of tumor marker test (CEA). From the shows solid sheets of atypical epithelioid cells, necrosis nuclear
Bronchoscopy found encouragement at the main right enlargement with size variation, hyperchromasia and frequent
bronchus. CT scan revealed solid inhomogenous mass at mitotic figures.
anterior mediastinal, invasion to sternum and superior
vena cava. Histopathological result from core needle Refferences
biopsy is nonkeratinizing squamous cell carsinoma of the 1. El-Naggar: WHO Classification of head and Neck Tumours, 4th
Thymus. The patient received radiation therapy and Edition, 2017, Semin Diagn Pathol 2015; 32: 54)
systemic chemotherapy by using carboplatin and 2. Bennisler L. Respiratory system. In: Gray’s anatomy. Williams PL,
paclitaxel regiments but exploratory thoracotomy was Bennisler L, Berry LH, Collins P, Dyson M,et al. Editors. 38 th ed,
not performed. Churchill Livingstone, Edinburgh, 1999.p. 1627-76