Laboratory

Standard
Laboratory use of
hazardous chemicals
 Chemical manipulations are
carried out on a laboratory
scale

 Multiple chemical procedures or

chemicals are used

1a
Laboratory use of
hazardous chemicals
 Procedures are not part of, and
do not simulate a production
process

 Protective laboratory practices

and equipment are available to
minimize employee exposure

1b
Permissible exposure
limits cannot be exceeded
 PEL is the level a person can be
regularly exposed to without
adverse effects
• Eight-hour time-weighted average
• Ceiling concentration limits
• Skin designation limits

2a
Permissible exposure
limits cannot be exceeded
 Action level is an exposure level
OSHA has designated for a
specific substance
• Eight-hour time-weighted average
• Exposures at action level initiate
exposure monitoring, medical
surveillance

2b
Exposure monitoring
 Measured when there is reason
to believe exposure levels
exceed action level or PEL

 Performed for substances

regulated by an OSHA standard
that requires monitoring

3a
Exposure monitoring
 Monitoring may be terminated in
accordance with regulation

 Employees must be notified of

monitoring results within 15
working days
• Individually
• Posting results in accessible location

3b
Chemical Hygiene Plan -
Basic operating procedures

 What to do for accidents and

spills

 How to avoid routine exposures

 How to choose chemicals

4a
Chemical Hygiene Plan -
Basic operating procedures

 Where to eat, drink, chew gum,

smoke, apply
cosmetics

4b
Chemical Hygiene Plan -
Basic operating procedures

 How to properly use glassware

and equipment

 Hygiene practices
upon leaving
laboratory

4c
Chemical Hygiene Plan -
Basic operating procedures

 Proper behavior in laboratory -

no horseplay

 How to pipette - no mouth

suction

 Appropriate personal apparel

and PPE
4d
Chemical Hygiene Plan -
Basic operating procedures

 Be aware of unsafe conditions -

plan ahead, follow warnings, work
under exhaust hoods

 Properly dispose of wastes

 Do not work alone when

performing hazardous procedures

4e
Chemical Hygiene Plan
 Potential laboratory hazards
• Allergens and Embryotoxins
• Moderate chronic and high acute
toxicity
• High chronic toxicity
• Animal work with chemicals of
high chronic toxicity

4f
Chemical Hygiene Plan
 Controls to reduce employee
exposure
• Engineering controls
• Work practice controls
• Hygiene practices
• PPE

4g
Chemical Hygiene Plan
 Ensure that fume hoods
function properly

 Employer approval is needed

before conducting some
operations, procedures,
activities

4h
Chemical Hygiene Plan
 Medical examinations and
consultation

4i
Chemical Hygiene Plan
 Personnel responsible for
implementation of hygiene plan
• Chemical
hygiene officer
• Chemical
hygiene
committee

4j
Chemical Hygiene Plan
 Provisions for employee
protection from:
• Select carcinogens
• Reproductive toxins
• Substances with high degree of
toxicity

4k
Chemical Hygiene Plan
 Provide information about:
• Designated areas
• Containment devices
• Safe removal of contaminated waste
• Decontamination procedures

 Review plan annually

4l
Training
 Location and availability of
MSDSs
 Training is required
upon initial
assignment,
and prior to new
exposure
situations

5a
Signs and symptoms of
exposure
 Each chemical has an MSDS

 Read MSDS to
determine signs
and symptoms
of exposure

6a
Methods of detection
of a release
 Monitoring is conducted

 Continuous monitoring devices

 Visual appearances

 Odor of hazardous chemicals

7a
Medical consultations/
examinations
 Reasons for medical attention

 Care provided by physician

without loss of pay

 Care provided at reasonable

time and place

8a
Medical consultations/
examinations
 Information provided to
physician
• Chemicals to which employee is
exposed
• Exposure conditions
• Signs and symptoms of exposure

8b
Medical consultations/
examinations
 Physician’s written opinion

 Confidentiality of information
not related
to exposure

8c
Labels
 Labels on
incoming
containers
cannot be
removed or
defaced

9a
Respirators - meet
1910.134 requirements
 Selection procedures

 Proper fit

 Proper use and care

 Limitations of respiratory
protection
10a
Recordkeeping
 Records retained for duration of
employment plus 30 years

 Includes tests and written

opinions

11a
Summary of main points
 Basic operating procedures

 PPE

 Hazards of chemicals used

 Signs and symptoms of

overexposure
12a
Summary of main points
 Detection methods of a release,
or presence of chemicals

 Permissible exposure limits

 Required monitoring

12b
Summary of main points
 Medical examination
requirements

 MSDSs and labels

 Respirator use

 Recordkeeping requirements
12c