OF BLOOD COMPONENTS DR THULASIRAM INTRODUCTION A sufficient number of units of varying ABO and RhD specificities should be available to meet routine hospital needs.
An unanticipated increases in utilization from
emergency situations, and minimize component expiration and wastage Factors that influence determination of blood bank component inventory levels include
historic usage patterns
expiration/wastage rates and distance from suppliers. Inventory levels should be periodically evaluated in response to institutional changes that may affect component usage, Including expansion of inpatient beds or operating rooms, Implementation of new surgical procedures, or changes in hospital guidelines or medical practice that may influence transfusion behavior. The blood bank should also maintain a reserve of universally compatible RBCs for emergency use
And have a reliable emergency delivery system to
ensure adequate availability of blood components in unexpected situations when demand exceeds supply. In platelet inventory shortage, medical directors may approve the splitting of apheresis platelet units or pooling of 3 whole blood-derived platelet units (vs the usual adult dose of 4-6 pooled units) for prophylactic transfusion orders to conserve inventory. Routine inventory levels should be monitored daily to facilitate timely ordering from blood suppliers and maintain adequate inventory levels.
This can be particularly challenging for platelets
because of their limited shelf life. Surgical Blood Ordering Practices Component outdate rates are influenced by surgical ordering practices. For example, when RBC units are cross matched for surgical recipients, they are unavailable to other recipients and have a greater likelihood of expiring if the component is not returned to the uncross matched inventory The crossmatch-to transfusion (C:T) ratio is the number of RBC units cross matched divided by the number of RBC units actually transfused
And is most useful in determining individual
physician or specialty specific ordering practices. When C:T ratios are monitored, a C:T ratio of >2.0 may indicate excessive ordering of cross matched blood .
And may identify instances when a preoperative type
and screen order is more appropriate. One approach to reducing excessive C:T ratios is to identify procedures that do not typically require blood,
and use this information to develop guidelines for the
use of type and screen orders or hold-sample orders
(samples that are received in the transfusion service
but do not have any testing orders) instead of cross match orders. The Maximum surgical blood order schedules MSBOS serves as a guideline not only for how many units should be available, but also for which surgical procedures require a type and screen or not. The electronic cross matching have decreased the utility of the MSBOS, and this practice is useful now primarily in hospital transfusion services that lack the ability to perform electronic cross matching. A discussion with the clinician and the blood bank staff should occur to determine how many units to crossmatch for recipients
undergoing elective surgery who are known to have
clinically significant allo antibodies and require cross match-compatible, antigen negative blood. Return of Blood Components and Reissue The transfusion service may receive back into inventory units that meet acceptance specifications. These conditions include the following
The container closure has not been disturbed.
The component has been maintained at the appropriate temperature. At least one sealed segment remains integrally attached to the container, if RBCs.
Documentation indicates that the component has
been inspected and is acceptable for reissue Individual-unit temperature indicators or temperature-reading devices can be used to determine the acceptability of components for return to inventory. Blood and blood components may also be transported or stored in qualified containers using a validated process that has been shown to maintain acceptable temperatures for a defined interval. Acceptable time frames for returning blood components to inventory after issue should be validated by individual facilities.
Individual-unit temperature indicators or
temperature-reading devices may be used to determine component acceptability for return to inventory. Components meeting the acceptance criteria may be returned to the general blood inventory and reissued.
Components not meeting the acceptance criteria must
be quarantined for further investigation or discarded in a biohazard container to prevent inadvertent return to inventory Key points Human Resources and Training Stock Levels and Order Patterns Transparency of Inventories and Simple Procedures Focus on Freshness of Stock Internal Collaboration within the Hospital THE END