Irungalur, Trichy - 621 105

AN EFFICIENT APPROACH FOR THE

DETECTION OF RETINOPATHY OF
PREMATURITY USING DEEP LEARNING
UNDER THE GUIDANCE OF
Dr. B. RAMASUBRAMANIAN
Vice Principal /HOD ECE
PRESENT BY
S. Priyadarshini -814718106033
V. Vinotha -814718106053

DEPARTMENT OF ELECTRONICS AND COMMUNICATION ENGINEERING

 ABSTRACT
• Retinopathy of Prematurity (ROP) is one of the main causes of childhood blindness. It is a
vascular proliferative retinal disease affecting premature and low birth-weight infants.
• Objective-To develop the automated screening system for diagnosis of ROP and evaluate the
performance of different deep learning network.
• First, if the images captured from the diabetic patients or else from the database.
• Second, the acquisition image that are taken from the database is input to the preprocessing.
• Preprocessed image is applied to the Deep Learning Network.
• Five different networks are deployed for the classification of normal and abnormal images.
• The best system out of these five networks will be identify and it will be proposed.
• Accuracy, Precision, Sensitivity, Specificity, ROC, AUC all the parameters will be measured, and
it will be compared.
• Our proposed system will outperform than all other existing system.

DEPARTMENT OF ECE, SRM TRP ENGINEERING COLLEGE,

10.05.2022
TRICHY.
 LITERATURE SURVEY
S.
No PAPER TITLE
1 Retinal image analysis using
machine learning
Graphical user interface for
2 enhanced retinal image analysis for
diagnosis diabetic retinopathy
Attention guided deep multi
3 instance learning for staging
retinopathy of prematurity
Retinal Vessel Segmentation Using
Deep Learning: A Review
4 segmentation including retinal
10.05.2022
AUTHOR
S. Prabha; S. Sai Ranjith Kumar;  July 28-30,
G. Gopal Reddy; K.Sakthidasan
Sankaran
B. Venkatalakshmi, V.Saravanan,
GJenny Niveditha
Shaobin chen, Rugang Zhang,
Guezhen Chen, Jinfeng Zhao, Tianfu
Wang, GuomingZhang, Baiying Lei.
Chunhui Chen , Joon Huang Chuah ,
Ali Raza, Yizhou Wang.
DEPARTMENT OF ECE, SRM TRP ENGINEERING COLLEGE,
TRICHY.
YEAR JOURNAL LIMITATION
IEEE Further the extracted blood vessels
are feed as an input to three
2020 International Conference on
techniques of machine learning such
Communication and Signal
Processing as SVM, logarithmic and KNN
algorithm. SVM shows accuracy of
84%.
2011 IEEE The main focus of the project is to
develop a GUI window, which has
TIFAC CORE in Pervasive
been developed with a good
Computing Technologies,
Velammal Engineering performance and success rate of 82%
College, Chennai
2021 IEEE The common models such as
AlexNet, VGG, ResNet50,
18th International
ResNet101 and Inceptionv4. Our
Symposium on Biomedical
Imaging (ISBI) method FCN+MIL had the best
accuracy 94.43 and sensitivity 92.71
2021 IEEE Access Currently, deep learning models have
been greatly used to image
images since they do not need any
handcrafted features and outperform
existing unsupervised methods.
 EXISTING SYSTEM
• The existing system focused only on one classifier to detect the Retinopathy of Prematurity (ROP).
• Through the analysis of these data, it takes too much time to produce a result.
• By using one classifier, detection is not sufficient for the Retinopathy of Prematurity.
• This type of classifier has a small application range which is not easy to identify the parameters.
• This system is focused on the traditional way of implementing the methodologies.

DEPARTMENT OF ECE, SRM TRP ENGINEERING COLLEGE,

10.05.2022
TRICHY.
 PROPOSED SYSTEM
• The propose system will be the effective method for Retinopathy of Prematurity (ROP).
• We use five different types of classifiers in Deep Learning such as AlexNet (Convolution neural
network that is 8 layers deep), VGG16 (16 layers deep neural networks), VGG19 (Advanced CNN
has 19 layer deep), GoogLeNet (Convolutional neural network that is 22 layers deep), and ResNet
(Residual Network database contains 60000, 32*32 color images in 10 different classes) it will be
produce the results in rapidly.
• This propose system will analyse the various types of parameters with more efficient than the
others.
• This system will classify network with more efficient to detect the Retinopathy of Prematurity
(ROP) in early stages.
• Accuracy, Precision, Sensitivity, Specificity, ROC, AUC all the parameters will be measured, and
it will be compared.

DEPARTMENT OF ECE, SRM TRP ENGINEERING COLLEGE,

10.05.2022
TRICHY.
 BLOCK DIAGRAM
DEEP LEARNING

Alex Net GoogLeNet VGG16

Image Preprocessing
IImage IImage
Acquisition
Res Net VGG19
Raspberry Pi

Normal Abnormal

Mild Moderate Severe

DEPARTMENT OF ECE, SRM TRP ENGINEERING COLLEGE,

10.05.2022
TRICHY.
 TOOLS USED
• HARDWARE USED
Raspberry Pi

• SOFTWARE USED
Python 3.8.1 with Deep Learning Open CV.
Operating system Linux.

DEPARTMENT OF ECE, SRM TRP ENGINEERING COLLEGE,

10.05.2022
TRICHY.
 REFERENCES

V. Yildiz et al., "Structural Visual Guidance Attention Networks In Retinopathy Of Prematurity," 2021 IEEE
18th International Symposium on Biomedical Imaging (ISBI), 2021, pp. 353-357, doi:
10.1109/ISBI48211.2021.9433881.

C. Chen, J. H. Chuah, R. Ali and Y. Wang, "Retinal Vessel Segmentation Using Deep Learning: A Review,“
in IEEE Access, vol. 9, pp. 111985-112004, 2021, doi: 10.1109/ACCESS.2021.3102176.

X. Li et al., "Deep Multiple Instance Learning with Spatial Attention for ROP Case Classification, Instance
Selection and Abnormality Localization," 2020 25th International Conference on Pattern Recognition (ICPR),
2021, pp. 7293-7298, doi: 10.1109/ICPR48806.2021.9412074.

Attallah, O. ‘’DIAROP: Automated Deep Learning-Based Diagnostic Tool for Retinopathy of
Prematurity’’. Diagnostics 2021, 11, 2034.

M. Z. Atwany, A. H. Sahyoun and M. Yaqub, "Deep Learning Techniques for Diabetic Retinopathy Classification:
A Survey," in IEEE Access, vol. 10, pp. 28642-28655, 2022, doi: 10.1109/ACCESS.2022.3157632.

Peng Y, Zhu W, Chen Z, Wang M, Geng L, Yu K, Zhou Y, Wang T, Xiang D, Chen F, Chen X. Automatic Staging
for Retinopathy of Prematurity With Deep Feature Fusion and Ordinal Classification Strategy. IEEE Trans Med
Imaging. 2021 Jul;40(7):1750-1762. doi: 10.1109/TMI.2021.3065753. Epub 2021 Jun 30. PMID: 33710954.

S. Chen et al., "Attention-guided Deep Multi-instance Learning for Staging Retinopathy of Prematurity," 2021
IEEE 18th International Symposium on Biomedical Imaging (ISBI), 2021, pp. 1025-1028, doi:
10.1109/ISBI48211.2021.9434012.
DEPARTMENT OF ECE, SRM TRP ENGINEERING COLLEGE,
10.05.2022
TRICHY.
 T. Nagi, M. Javed Awan, R. Javed and N. Ayesha, "A Comparison of Two-Stage Classifier Algorithm with
Ensemble Techniques On Detection of Diabetic Retinopathy," 2021 1st International Conference on
Artificial Intelligence and Data Analytics (CAIDA), 2021, pp. 212-215, doi:
10.1109/CAIDA51941.2021.9425129.
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Applications in Clinical Settings", Journal of Healthcare Engineering, vol. 2018, Article
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 B. M. ter Haar Romeny, "Vision for Vision — Deep Learning in Retinal Image Analysis," 2018 Signal
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10.23919/SPA.2018.8563421.
 M. C. V. Stella Mary, E. B. Rajsingh and G. R. Naik, "Retinal Fundus Image Analysis for Diagnosis of
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 T. Wu, L. Zhang, Y. Tong, Y. Qu, B. Xia, and D. Mu, "Retinopathy of Prematurity Among Very Low-Birth-
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DEPARTMENT OF ECE, SRM TRP ENGINEERING COLLEGE,
10.05.2022
TRICHY.
 THANK
YOU

10.05.2022 DEPARTMENT OF ECE, SRM TRP ENGINEERING COLLEGE, TRICHY.