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Tutorial Case 3

Tutor A2

Acquired Immune
Deficiency Syndrome
(AIDS)
Nabila Fairuz
1910211038
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● AIDS = kumpulan gejala yang diakibatkan oleh berbagai macam patogen
akibat menurunnya daya tahan tubuh

● HIV → imunitas menurun → patogen → Infeksi Oportunisitik

● AIDS = <200 sel T/mm3 = Stadium HIV Lanjut

● NonProgressor = develop Aids very slowly or never at all → genetic difference that
prevent the virus from significantly damaging immune system

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Penderita HIV butuh ARV untuk menurunkan jumlah virus agar tidak masuk
ke stadium AIDS

Penderita AIDS butuh ARV untuk cegah terjadinya infeksi oportunistik dan
komplikasinya

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Infeksi Oportunistik
Viral Infetion Bacterial Infetion
• Cytomegalovirus (CMV) -> • Recurrent bacterial pneumonia (commonly
Herpes simplex, chicken Streptococcus pneumoniae)
pox • Mycobacterium tuberculosis
• Molluscum contagiosum - • Non-tuberculosis mycobacteriosis
> bintil kulit (particularly M. avium-intracellulare
• Herpes zoster complex)
• Campak • Systemic non-typhoid Salmonella
• Kutil kelamin, kanker infections* (notably S. enteritidis and S.
• Sarkoma Kaposi : kanker typhimurium)
yg menyebabkan lesi pada • Pseudomonas spp. septicaemia and
jaringan lunak `vasculitis'
• Epstein-Barr virus (EBV) • Bartonella spp. (causing bacillary
angiomatosis) 6
Fungal Infection Tumor
• Candida severe infection • Kaposi's sarcoma
• Pneumocystis jiroveci • Primary cerebral lymphoma
pneumonia • High-grade non-Hodgkin
• Cryptococcus neoformans lymphoma
• Histoplasma capsulatum • Carcinoma (invasive) of the
• Coccidioides immitis cervix
• Aspergillus spp. • Carcinoma of the conjunctiva
• Penicillium marneffei • Carcinoma of the anus
• Protozoal infections • T-cell lymphoma
• Toxoplasma gondii • Hodgkin's disease
• Cryptosporidium parvum • Lymphoproliferative disease,
• Isospora belli pre-lymphomatous
• Leishmania spp.
• Microsporidia spp.
• Acanthamoeba spp.
• Trypanosoma cruzi
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Lainnya
• HIV-wasting syndrome (fever, weight loss, diarrhoea)
• HIV-associated dementia or memory loss
• Various dermatitis patterns (e.g. pruritic rash, eosinophilic folliculitis)
• Skeletal myopathy
• Peripheral and autono
• Peripheral and autonomic neuropathy
• Cardiomyopathy
• Pulmonary hypertension
• Vasculitis
• HIV-associated nephropathy (HIVAN)
• Haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopaenic
purpura (TTP)
• Oral and oesophageal ulcers
• Dyshaemopoiesis and marrow serous atrophy
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Gejala

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REFERENSI

• Infodatin Kemenkes 2020


• Konsulat Jenderal Republik Indonesia
https://kemlu.go.id/download/L1NoYXJlZCUyMERvY3VtZW50cy9UQUJMT0lEL3R
hYmxvaWQlMjBCcm9zdXIlMjBBSURTLnBkZg==

• Informasi Dasar HIV & AIDS. Buku Kader Pemberdayaan Kampung 2017
• https://www.news-medical.net/health/AIDS-Pathophysiology.aspx#:~:text=Acq
uired%20immune%20deficiency%20syndrome%20(AIDS,opportunistic%20infe
ctions%20and%20certain%20cancers
.

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THANKS
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