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Translated from Indonesian to English - www.onlinedoctranslator.

com

Pathophysiology cough
Cough is effort defense lungs to various
stimulationwhichthere isandreflex
physiologicalwhichprotect lungs
fromtraumatizedmechanic,chemicalandtemper
ature.Cough Becomes pathological when felt as
disturbance.Cough like that often is sign
something diseaseinin or outside
lungsandsometimes form symptom beginning
from something disease.Cough is symptom
most common disease
respirationandproblemwhichoftentimefaced
● Cough could occur becausenormal processor pathology.Coughwhich is normalcould occur because no intentional nor
intentional.Generally cough is something reflexwhichcould arise consequence exists excitatory good mechanical,
chemical nor irritant.
● Component reflex cough composed from receptor,nerve afferent,center cough,nerve efferentandeffector
● Receptors cough:larynx,trachea, bronchi,ear.stomach,nose, paranasal sinuses,farings, andpericardium as well as
diaphragm.
● The nervesrole as nerve afferent: n. vagusnphrenicus, and n .trigeminal.
● Centercough:spread in a manner equallyonmedulla close center respiration.
● The nervesrole as nerve efferent:nvagus, n frenykus,dannintercostals
● effector oreally: onlarynx, trachea,bronchi,diaphragm, andintercostal
● Adava stimulationonreceptor cough will continuedbynerve afferent to center coughinmedulla. Dari center cough,
impulse nerve continued going to to effector vatu a number of musclewhichrole inprocessrespiratory_
● Stimulationonreceptor could characteristic exogenous norendogenous.
● pattern coughwhichoccur dependonthe placeandtype stimulation.
● Generally stimulation mechanic cause sensitiveonchannel respiratory proximal
● whereas respiratorydistalmore sensitive to stimulation chemical.
Phase–phase cough
● Chung, K.F.Pavord, ID 2008. Prevalence,
pathogenesis, and causes of chronic cough.
Experimental Studies Airway Disease Section.
371:1364–74.
● Bucher K Pathophysiology and pharmacology
ofcough. PharmacolRev. 1958; 10:43-58

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